302
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Differential Circular RNA Expression Profiling During Osteogenic Differentiation in Human Adipose-Derived Stem Cells

, , , , &
Pages 289-302 | Received 16 Dec 2019, Accepted 10 Jan 2020, Published online: 13 Feb 2020

References

  • Rada T , ReisRL , GomesME. Adipose tissue-derived stem cells and their application in bone and cartilage tissue engineering. Tissue Eng. Part B Rev.15(2), 113–125 (2009).
  • Im GI . Bone marrow-derived stem/stromal cells and adipose tissue-derived stem/stromal cells: their comparative efficacies and synergistic effects. J. Biomed. Mater. Res. A105(9), 2640–2648 (2017).
  • Huang S , YangB , ChenBJet al. The emerging role of circular RNAs in transcriptome regulation. Genomics109(5–6), 401–407 (2017).
  • Jeck WR , SharplessNE. Detecting and characterizing circular RNAs. Nat Biotechnol.32(5), 453–461 (2014).
  • Wilusz JE . A 360° view of circular RNAs: from biogenesis to functions. Wiley Interdiscip. Rev. RNA9(4), e1478 (2018).
  • Sanger HL , KlotzG , RiesnerD , GrossHJ , KleinschmidtAK. Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures. Proc. Natl Acad. Sci. USA73(11), 3852–3856 (1976).
  • Haque S , HarriesLW. Circular RNAs (circRNAs) in health and disease. Genes (Basel).8(12), pii: E353 (2017).
  • de Fraipont F , GazzeriS , ChoWC , EyminB. Circular RNAs and RNA splice variants as biomarkers for prognosis and therapeutic response in the liquid biopsies of lung cancer patients. Front. Genet.10, 390 (2019).
  • Suzuki H , TsukaharaT. A view of pre-mRNA splicing from RNase R resistant RNAs. Int. J. Mol. Sci.15(6), 9331–9342 (2014).
  • Cai J , ChenZ , ZuoX. circSMARCA5 functions as a diagnostic and prognostic biomarker for gastric cancer. Dis. Markers.2019, 2473652 (2019).
  • Zeng Y , DuWW , WuYet al. A circular RNA binds to and activates AKT phosphorylation and nuclear localization reducing apoptosis and enhancing cardiac repair. Theranostics7(16), 3842–3855 (2017).
  • Kumar L , Shamsuzzama , HaqueR , BaghelT , NazirA. Circular RNAs: the emerging class of non-coding RNAs and their potential role in human neurodegenerative diseases. Mol. Neurobiol.54(9), 7224–7234 (2017).
  • Chen BJ , HuangS , JanitzM. Changes in circular RNA expression patterns during human foetal brain development. Genomics111(4), 753–758 (2019).
  • Zheng Q , BaoC , GuoWet al. Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs. Nat. Commun.7, 11215 (2016).
  • Chen H , MaoM , JiangJ , ZhuD , LiP. Circular RNA CDR1as acts as a sponge of miR-135b-5p to suppress ovarian cancer progression. Onco. Targets Ther.12, 3869–3879 (2019).
  • Peng W , ZhuS , ChenJ , WangJ , RongQ , ChenS. Hsa_circRNA_33287 promotes the osteogenic differentiation of maxillary sinus membrane stem cells via miR-214-3p/Runx3. Biomed. Pharmacother.109, 1709–1717 (2019).
  • Yang R , XingL , ZhengX , SunY , WangX , ChenJ. The circRNA circAGFG1 acts as a sponge of miR-195-5p to promote triple-negative breast cancer progression through regulating CCNE1 expression. Mol. Cancer18(1), 4 (2019).
  • Zhang X , LiuX , JingZet al. The circINTS4/miR-146b/CARMA3 axis promotes tumorigenesis in bladder cancer. Cancer Gene Ther. (2019). Supplementary Table 1
  • Huang X , CenX , ZhangBet al. The roles of circRFWD2 and circINO80 during NELL-1- induced osteogenesis. J. Cell. Mol. Med.23(12), 8432–8441 (2019).
  • Li X , PengB , ZhuXet al. Changes in related circular RNAs following ERβ knockdown and the relationship to rBMSC osteogenesis. Biochem. Biophys. Res. Commun.493(1), 100–107 (2017).
  • Li X , ZhengY , ZhengYet al. Circular RNA CDR1as regulates osteoblastic differentiation of periodontal ligament stem cells via the miR-7/GDF5/SMAD and p38 MAPK signaling pathway. Stem Cell Res. Ther.9(1), 232 (2018).
  • Bunnell BA , FlaatM , GagliardiC , PatelB , RipollC. Adipose-derived stem cells: isolation, expansion and differentiation. Methods45(2), 115–120 (2008).
  • Gaur M , DobkeM , LunyakVV. Methods and strategies for procurement, isolation, characterization, and assessment of senescence of human mesenchymal stem cells from adipose tissue. Methods Mol. Biol.2045, 37–92 (2019).
  • Bourin P , BunnellBA , CasteillaLet al. Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT). Cytotherapy15(6), 641–648 (2013).
  • Dominici M , LeBlanc K , MuellerIet al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy8(4), 315–317 (2006).
  • Xu J , KangY , LiaoWM , YuL. MiR-194 regulates chondrogenic differentiation of human adipose-derived stem cells by targeting Sox5. PLoS ONE7(3), e31861 (2012).
  • Gou Q , WuK , ZhouJKet al. Profiling and bioinformatic analysis of circular RNA expression regulated by c-Myc. Oncotarget8(42), 71587 (2017).
  • Li Z , LiN , GeXet al. Differential circular RNA expression profiling during osteogenic differentiation of stem cells from apical papilla. Epigenomics11(9), 1057–1073 (2019).
  • Hansen KD , WuZ , IrizarryRAet al. Sequencing technology does not eliminate biological variability. Nat. Biotechnol.29(7), 572 (2011).
  • Auer PL , DoergeRW. Statistical design and analysis of RNA sequencing data. Genetics185(2), 405–416 (2010).
  • Jalilian S , TeimooriA , MakvandiM , ZandiM. An in vitro transcription assay for development of Rotavirus VP7. Iran. J. Microbiol.9(3), 186–194 (2017).
  • Franks JM , CaiG , WhitfieldML. Feature specific quantile normalization enables cross-platform classification of molecular subtypes using gene expression data. Bioinformatics34(11), 1868–1874 (2018).
  • Long T , GuoZ , HanLet al. Differential expression profiles of circular RNAs during osteogenic differentiation of mouse adipose-derived stromal cells. Calcif. Tissue Int.103(3), 338–352 (2018).
  • Enright AJ , JohnB , GaulU , TuschlT , SanderC , MarksDS. MicroRNA targets in DrosophilaGenome Biol.5(1), R1 (2003).
  • Pasquinelli AE . MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. Nat. Rev. Genet.13(4), 271–282 (2012).
  • Wang Y , WuS , YangCet al. Construction and analysis of circRNA-miRNA-mRNA molecular regulatory networks during herba Gelsemium elegans intoxication. Front. Pharmacol.10, 1217 (2019).
  • Zuk PA , ZhuM , MizunoHet al. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng.7(2), 211–228 (2001).
  • Zuk PA , ZhuM , AshjianPet al. Human adipose tissue is a source of multipotent stem cells. Mol. Biol. Cell13(12), 4279–4295 (2002).
  • Li L , GuoJ , ChenY , ChangC , XuC. Comprehensive CircRNA expression profile and selection of key CircRNAs during priming phase of rat liver regeneration. BMC Genomics18(1), 80 (2017).
  • Yang ZG , AwanFM , DuWWet al. The circular RNA interacts with STAT3, increasing its nuclear translocation and wound repair by modulating Dnmt3a and miR-17 function. Mol. Ther.25(9), 2062–2074 (2017).
  • Gu X , LiM , JinY , LiuD , WeiF. Identification and integrated analysis of differentially expressed lncRNAs and circRNAs reveal the potential ceRNA networks during PDLSC osteogenic differentiation. BMC Genet.18(1), 100 (2017).
  • Li Y , ZhangJ , HuoCet al. Dynamic organization of lncRNA and circular RNA regulators collectively controlled cardiac differentiation in humans. E. Bio. Med.24, 137–146 (2017).
  • Lai Z , YangY , YanYet al. Analysis of co-expression networks for circular RNAs and mRNAs reveals that circular RNAs hsa_circ_0047905, hsa_circ_0138960 and has-circRNA7690-15 are candidate oncogenes in gastric cancer. Cell Cycle16(23), 2301–2311 (2017).
  • Bachmayr-Heyda A , ReinerAT , AuerKet al. Correlation of circular RNA abundance with proliferation – exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues. Sci. Rep.5, 8057 (2015).
  • Chen PC , LiuJF , FongYCet al. CCN3 facilitates Runx2 and Osterix expression by inhibiting miR-608 through PI3K/Akt signaling in osteoblasts. Int. J. Mol. Sci.20(13), 3300 (2019).
  • Fröhlich LF . MicroRNAs at the interface between osteogenesis and angiogenesis as targets for bone regeneration. Cells.8(2), pii: E121 (2019).
  • Shao W , YuanL , SuS , XinZ , MaJ , WangS. MIRNA-705 Regulates the osteogenic differentiation of adipose-derived stem cells in the microenvironment of osteoporosis. J. Biomater. Tiss. Eng.9(1), 119–123 (2019).
  • Atashi F , ModarressiA , PepperMS. The role of reactive oxygen species in mesenchymal stem cell adipogenic and osteogenic differentiation: a review. Stem Cells Dev.24(10), 1150–1163 (2015).
  • An J , YangH , ZhangQet al. Natural products for treatment of osteoporosis: the effects and mechanisms on promoting osteoblast-mediated bone formation. Life Sci.147, 46–58 (2016).
  • Chen D , GongY , XuL , ZhouM , LiJ , SongJ. Bidirectional regulation of osteogenic differentiation by the FOXO subfamily of Forkhead transcription factors in mammalian MSCs. Cell Prolif.52(2), e12540 (2019).
  • Tsang EJ , WuB , ZukP. MAPK signaling has stage-dependent osteogenic effects on human adipose-derived stem cells in vitro. Connect. Tissue Res.59(2), 129–146 (2018).
  • Yang Y , ChoiH , SeonM , ChoD , BangSI. LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway. Stem Cell Res. Ther.7(1), 58 (2016).
  • Pan BL , TongZW , LiSDet al.Decreased microRNA-182-5p helps alendronate promote osteoblast proliferation and differentiation in osteoporosis via the Rap1/MAPK pathway. Biosci. Rep.38(6), pii: BSR20180696 (2018).
  • Bai M , YinH , ZhaoJ , LiY , WuY. miR-182-5p overexpression inhibits chondrogenesis by down-regulating PTHLH. Cell Biol. Int.43(3), 222–232 (2019).
  • Liu F , WangX , YangY , HuR , WangW , WangY. The suppressive effects of miR-508-5p on the odontogenic differentiation of human dental pulp stem cells by targeting glycoprotein non-metastatic melanomal protein B. Stem Cell Res. Ther.10(1), 35 (2019).
  • Geng Q , YuS , ZhangY , WangH , SunF. miR-376b-3p promotes Runx2-induced early osteogenic differentiation of C2C12 cells. Chinese J. Tissue Eng. Res.17(28), 5108–5112 (2013).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.