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Review

From Discovery to the Clinic: The Novel DNA Methylation Biomarker mSEPT9 For The Detection of Colorectal Cancer in Blood

Pages 575-585 | Published online: 05 Aug 2010

Bibliography

  • Laird PW , JaenischR: The role of DNA methylation in cancer genetic and epigenetics.Annu. Rev. Genet.30 , 441–464 (1996).
  • Wolffe AP , MatzkeMA: Epigenetics: regulation through repression.Science286(5439) , 481–486 (1999).
  • Issa JP : The epigenetics of colorectal cancer.Ann. NY Acad. Sci.910 , 140–153; discussion 153–145 (2000).
  • Markowitz SD , BertagnolliMM: Molecular origins of cancer: molecular basis of colorectal cancer.N. Engl. J. Med.361(25) , 2449–2460 (2009).
  • Kramer BS , CroswellJM: Cancer screening: the clash of science and intuition.Annu. Rev. Med.60 , 125–137 (2009).
  • Mandel JS , BondJH, ChurchTRet al.: Reducing mortality from colorectal cancer by screening for fecal occult blood. Minnesota colon cancer control study.N. Engl. J. Med.328(19) , 1365–1371 (1993).
  • Winawer SJ , ZauberAG, HoMNet al.: Prevention of colorectal cancer by colonoscopic polypectomy. The national polyp study workgroup.N. Engl. J. Med.329(27) , 1977–1981 (1993).
  • Baxter NN , GoldwasserMA, PaszatLF, SaskinR, UrbachDR, RabeneckL: Association of colonoscopy and death from colorectal cancer.Ann. Intern. Med.150(1) , 1–8 (2009).
  • Jemal A , SiegelR, WardE, HaoY, XuJ, ThunMJ: Cancer statistics, 2009.CA Cancer J. Clin.59(4) , 225–249 (2009).
  • Hofstetter W , SwisherSG, CorreaAMet al.: Treatment outcomes of resected esophageal cancer.Ann. Surg.236(3) , 376–384; discussion 384–375 (2002).
  • Internullo E , MoonsJ, NafteuxPet al.: Outcome after esophagectomy for cancer of the esophagus and gej in patients aged over 75 years.Eur. J. Cardiothorac. Surg.33(6) , 1096–1104 (2008).
  • Sakr WA , HaasGP, CassinBF, PontesJE, CrissmanJD: The frequency of carcinoma and intraepithelial neoplasia of the prostate in young male patients.J. Urol.150(2 Pt 1) , 379–385 (1993).
  • Warren JL , KlabundeCN, MariottoABet al.: Adverse events after outpatient colonoscopy in the medicare population.Ann. Intern. Med.150(12) , 849–857, W152 (2009).
  • Allen JD , BarlowWE, DuncanRPet al.: NIH state-of-the-science conference draft statement: enhancing use and quality of colorectal screening.NIH Consens. State Sci. Statements27(1) , 1–21 (2010).
  • Mandel JS , ChurchTR, BondJHet al.: The effect of fecal occult-blood screening on the incidence of colorectal cancer.N. Engl. J. Med.343(22) , 1603–1607 (2000).
  • Shapiro JA , SeeffLC, ThompsonTD, NadelMR, KlabundeCN, VernonSW: Colorectal cancer test use from the 2005 national health interview survey.Cancer Epidemiol. BiomarkersPrev. 17(7) , 1623–1630 (2008).
  • Mandel P , MetaisP: Les acides nucleiques du plasma sanguin chez l‘homme.C. R. Seances Soc. Biol. Fil.142(3–4) , 241–243 (1948).
  • O‘Mullan P , CraftD, YiJ, GelfandCA: Thrombin induces broad spectrum proteolysis in human serum samples.Clin. Chem. Lab. Med.47(6) , 685–693 (2009).
  • Laird PW : Principles and challenges of genome-wide DNA methylation analysis.Nat. Rev. Genet.11(3) , 191–203
  • Lofton-Day C , LescheR: DNA methylation markers in patients with gastrointestinal cancers. Current understanding, potential applications for disease management and development of diagnostic tools.Dig. Dis.21(4) , 299–308 (2003).
  • Gonzalgo ML , LiangG, SpruckCH 3rd, Zingg JM, Rideout WM 3rd, Jones PA: Identification and characterization of differentially methylated regions of genomic DNA by methylation-sensitive arbitrarily primed PCR. Cancer Res.57(4) , 594–599 (1997).
  • Toyota M , HoC, AhujaNet al.: Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification.Cancer Res.59(10) , 2307–2312 (1999).
  • Shi H , YanPS, ChenCMet al.: Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells.Cancer Res.62(11) , 3214–3220 (2002).
  • Fassbender A , LewinJ, KonigTet al.: Quantitative DNA methylation profiling on a high-density oligonucleotide microarray.Methods Mol. Biol.576 , 155–170 (2010).
  • Model F , OsbornN, AhlquistDet al.: Identification and validation of colorectal neoplasia-specific methylation markers for accurate classification of disease.Mol. Cancer Res.5(2) , 153–163 (2007).
  • Sozzi G , ConteD, LeonMet al.: Quantification of free circulating DNA as a diagnostic marker in lung cancer.J. Clin. Oncol.21(21) , 3902–3908 (2003).
  • Papadopoulou E , DavilasE, SotiriouVet al.: Cell-free DNA and RNA in plasma as a new molecular marker for prostate and breast cancer.Ann. NY Acad. Sci.1075 , 235–243 (2006).
  • Weiss G , RoschT: Potential of a new blood test for colorectal cancer screening – the septin 9 gene biomarker.European Oncology6(1) , 1–4 (2010).
  • Lofton-Day C , ModelF, DevosTet al.: DNA methylation biomarkers for blood-based colorectal cancer screening.Clin. Chem.54(2) , 414–423 (2008).
  • Hartwell LH , CulottiJ, ReidB: Genetic control of the cell-division cycle in yeast. I. Detection of mutants.Proc. Natl Acad. Sci. USA66(2) , 352–359 (1970).
  • Hall PA , RussellSE: The pathobiology of the septin gene family.J. Pathol.204(4) , 489–505 (2004).
  • Russell SE , McilhattonMA, BurrowsJFet al.: Isolation and mapping of a human septin gene to a region on chromosome 17q, commonly deleted in sporadic epithelial ovarian tumors.Cancer Res.60(17) , 4729–4734 (2000).
  • Strehl S , KonigM, MeyerCet al.: Molecular dissection of t(11;17) in acute myeloid leukemia reveals a variety of gene fusions with heterogeneous fusion transcripts and multiple splice variants.Genes Chromosomes Cancer45(11) , 1041–1049 (2006).
  • Kreuziger LM , PorcherJC, KetterlingRP, SteensmaDP: A mixed-lineage leukemia-SEPT9 fusion and t(11;17)(q23;q25) associated with de novo myelodysplastic syndrome.Leuk. Res.31(8) , 1145–1148 (2007).
  • McDade SS , HallPA, RussellSE: Translational control of SEPT9 isoforms is perturbed in disease.Hum. Mol. Genet.16(7) , 742–752 (2007).
  • Pepe MS , EtzioniR, FengZet al.: Phases of biomarker development for early detection of cancer.J. Natl Cancer Inst.93(14) , 1054–1061 (2001).
  • Bossuyt PM , ReitsmaJB, BrunsDEet al.: Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Standards for reporting of diagnostic accuracy.Clin. Chem.49(1) , 1–6 (2003).
  • Devos T , TetznerR, ModelFet al.: Circulating methylated SEPT9 DNA in plasma is a biomarker for colorectal cancer.Clin. Chem.55(7) , 1337–1346 (2009).
  • Hall HI , Van Den Eeden SK, Tolsma DD et al.: Testing for prostate and colorectal cancer: comparison of self-report and medical record audit. Prev. Med.39(1) , 27–35 (2004).
  • Brenner H , HoffmeisterM, StegmaierC, BrennerG, AltenhofenL, HaugU: Risk of progression of advanced adenomas to colorectal cancer by age and sex: estimates based on 840,149 screening colonoscopies.Gut56(11) , 1585–1589 (2007).
  • Ross JS : Multigene classifiers, prognostic factors, and predictors of breast cancer clinical outcome.Adv. Anat. Pathol.16(4) , 204–215 (2009).
  • Gibbs J : Regulatory pathways for molecular dx: detailing the various options available and what each requires.Genetic Engineering & Biotechnology News2828(14) , 1– (2008).
  • Slodkwoska EA , RossJS: Mammaprint 70-gene signature: another milestone in personalized medical care for breast cancer patients.Expert Rev. Mol. Diagn9(5) , 417–422 (2009).

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