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Editorial

Does Infection of Cerebellar Purkinje Neurons with Human Herpes Virus 6A or 6B (HHV-6) Increase the Risk of Developing Mood Disorders?

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Pages 85-88 | Received 09 Nov 2018, Accepted 28 Nov 2018, Published online: 15 Jan 2019

References

  • Craddock N , FortyL . Genetics of affective (mood) disorders . Eur. J. Human Genet.14 ( 6 ), 660 – 668 ( 2006 ).
  • Parboosing R , BaoY , ShenL , SchaeferCA , BrownAS . Gestational influenza and bipolar disorder in adult offspring . JAMA Psychiatry70 ( 7 ), 677 – 685 ( 2013 ).
  • Sutterland AL , FondG , KuinAet al. Beyond the association. Toxoplasma gondii in schizophrenia, bipolar disorder, and addiction: systematic review and meta-analysis . Acta Psychiatr. Scand.132 ( 3 ), 161 – 179 ( 2015 ).
  • Wang X , ZhangL , LeiYet al. Meta-analysis of infectious agents and depression . Sci. Rep.4 , 4530 ( 2014 ).
  • Prusty BK , GulveN , GovindSet al. Active HHV-6 infection of cerebellar Purkinje cells in mood disorders . Front. Microbiol.9 , 1955 ( 2018 ).
  • Agut H , BonnafousP , Gautheret-DejeanA . Laboratory and clinical aspects of human herpesvirus 6 infections . Clin. Microbiol. Rev.28 ( 2 ), 313 – 335 ( 2015 ).
  • Scola G , DuongA . Prenatal maternal immune activation and brain development with relevance to psychiatric disorders . Neuroscience346 , 403 – 408 ( 2017 ).
  • Ajdacic-Gross V , AleksandrowiczA , RodgersSet al. Social phobia is associated with delayed onset of chickenpox, measles, and mumps infections . Front. Psychiatry7 , 203 ( 2016 ).
  • Thacker EL , MirzaeiF , AscherioA . Infectious mononucleosis and risk for multiple sclerosis: a meta-analysis . Ann. Neurol.59 ( 3 ), 499 – 503 ( 2006 ).
  • Benros ME , WaltoftBL , NordentoftMet al. Autoimmune diseases and severe infections as risk factors for mood disorders: a nationwide study . JAMA Psychiatry70 ( 8 ), 812 – 820 ( 2013 ).
  • Tylee DS , SunJ , HessJLet al. Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data . Am J Med Genet B Neuropsychiatr Genet . 177 ( 17 ), 641 – 657 ( 2018 ).
  • Linnoila JJ , BinnickerMJ , MajedM , KleinCJ , McKeonA . CSF herpes virus and autoantibody profiles in the evaluation of encephalitis . Neurol. Neuroimmunol. Neuroinflamm.3 ( 4 ), e245 ( 2016 ).
  • Spatola M , Petit-PedrolM , SimabukuroMMet al. Investigations in GABAA receptor antibody-associated encephalitis . Neurology88 ( 11 ), 1012 – 1020 ( 2017 ).
  • Dickerson F , StallingsC , VaughanC , OrigoniA , KhushalaniS , YolkenR . Antibodies to the glutamate receptor in mania . Bipolar Disord.14 ( 5 ), 547 – 553 ( 2012 ).
  • Leibovitch EC , CarusoB , HaSKet al. Herpesvirus trigger accelerates neuroinflammation in a nonhuman primate model of multiple sclerosis . Proc. Natl Acad. Sci. U S A115 ( 44 ), 11292 – 11297 ( 2018 ).
  • Leto K , ArancilloM , BeckerEBet al. Consensus paper: cerebellar development . Cerebellum15 ( 6 ), 789 – 828 ( 2016 ).
  • Reynaud JM , JegouJF , WelschJC , HorvatB . Human herpesvirus 6A infection in CD46 transgenic mice: viral persistence in the brain and increased production of proinflammatory chemokines via Toll-like receptor 9 . J. Virol.88 ( 10 ), 5421 – 5436 ( 2014 ).
  • Readhead B , Haure-MirandeJV , FunkCCet al. Multiscalenalysis of independent Alzheimer‘s cohorts finds disruption of molecular, genetic, and clinical networks by human herpesvirus . Neuron99 ( 1 ), 64 – 82 ( 2018 ).
  • Prusty BK , GulveN , ChowdhurySRet al. HHV-6 encoded small non-coding RNAs define an intermediate and early stage in viral reactivation . NPJ Genom. Med.3 , 25 ( 2018 ).
  • Bycroft C , FreemanC , PetkovaDet al. The UK Biobank resource with deep phenotyping and genomic data . Nature562 ( 7726 ), 203 – 209 ( 2018 ).
  • Chen Z , ChenJ , CollinsRet al. China Kadoorie Biobank of 0.5 million people: survey methods, baseline characteristics and long-term follow-up . Int. J. Epidemiol.40 ( 6 ), 1652 – 1666 ( 2011 ).
  • Bassig BA , Willhauck-FleckensteinM , ShuXOet al. Serologic markers of viral infection and risk of non-Hodgkin lymphoma: a pooled study of three prospective cohorts in China and Singapore . Int. J. Cancer143 ( 3 ), 570 – 579 ( 2018 ).

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