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Research Article

Antimicrobial susceptibility Patterns of Bacteria that Commonly Cause Bacteremia at a Tertiary Hospital in Zambia

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Pages 1735-1745 | Received 09 Oct 2020, Accepted 25 Nov 2020, Published online: 14 Dec 2020

References

  • Schellack N , MessinaA. “Esprit de corps”: towards collaborative integration of pharmacists and nurses into antimicrobial stewardship programmes in South Africa. S. Afr. Med. J.106(10), 973–974 (2016).
  • Bulabula N , JekinsA , MehtarS , NathwaniD. Education and management of antimicrobials amongst nurses in Africa a situation analysis: An Infection Control Africa Network (ICAN)/BSAC online survey. J. Antimicrob. Chemother.73(5), 1408–1415 (2018).
  • Musicha P , CornickJ , Bar-ZeevNet al. Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998–2016): a surveillance study. Lancet Infect. Dis.17(10), 1042–1052 (2017).
  • Gajdács M . The concept of an ideal antibiotic: implications for drug design. Molecules24, 892 (2019).
  • Gajdács M , AlbericioF. Antibiotic resistance: from the bench to patients. Antibiotics8, 129 (2019).
  • Christaki E , Giamarellos-BourboulisJ. The complex pathogenesis of bacteremia: from antimicrobial clearance mechanisms to the genetic background of the host. Virulence5(1), 57–65 (2014).
  • Bennett L , BeesonB. Bacteremia: a consideration of some experimental and clinical aspects. Yale J. Biol. Med.26(4), 241–262 (1954).
  • Guimaraes O , CaoK , HongO , MaybaM. A prognostic model of persistent bacteremia and mortality in complictated Staphylococcus aureus bloodstream infection. Clin. Infect. Dis.68(9), 1502–1511 (2019).
  • Ahmed N , HussainT. Antimicrobial susceptibility patterns of leading bacterial pathogens isolated from laboratory confirmed blood stream infections in a multi-specialty sanatorium. J. Glob. Infect Dis.6, 141–146 (2014).
  • Reddy A , ShawV , CrumpA. Community-acquired bloodstream infections in Africa: a systematic review and meta-analysis. Lancet Infect. Dis.10(6), 417–432 (2010).
  • Tambekar D , DhanorkarD , GulhaneSet al. Bacterial pathogens and their antimicrobial susceptibility in Gaza strip, Palestine. J. Med. Sci.7, 493–496 (2014).
  • Pourakbari B , SadrA , AshtianiMet al. Five-year evaluation of the antimicrobial susceptibility patterns of bacteria causing bloodstream infections in Iran. J. Infect. Dev. Ctries.6(2), 120–125 (2012).
  • Ugrakli S , OkumuşE , DoğanM. Identification of bacterial pathogens in blood specimens and antibiotic resistance profiles of Acinetobacter species in a University Hospital, Kenya. J. Clin. Microbiol. Biochem. Technol.3(1), 004–008 (2017).
  • Asante K , BoamahE , AbdulaiMet al. Knowledge of antibiotic resistance and antibiotic prescription practices among prescribers in the Brong Ahafo Region of Ghana; a cross-sectional study. BMC Health. Serv. Res.17(1), 422 (2017).
  • Leopold S , van LethF , TarekegnH , SchultszC. Antimicrobial drug resistance among clinically relevant bacterial isolates in sub-Saharan Africa: a systematic review. J. Antimicrob. Chemother.69, 2337–2353 (2014).
  • Farley E , StewartA , DaviesM , GovindM , vanden Bergh D , BoylesT. Antibiotic use and resistance: knowledge, attitudes and perceptions among primary care prescribers in South Africa. S. Afr. Med. J.108(9), 763–771 (2018).
  • Rehman I , AsadM , BukhshAet al. Knowledge and practice of pharmacists toward antimicrobial Stewardship in Pakistan. Pharmacy6, 116 (2018).
  • Berha A , AminD , AlebachewM. Awareness and beliefs of antimicrobial resistance among health professionals working at Tikur Anbessa Specialized Hospital, Addis Ababa: Ethiopia. J. Bioanal. Biomed.9, 123–129 (2017).
  • De Kraker M , JarlierV , MonemJ , HeuerO , Vande Sande N , GrundmannH. The changing epidemiology of bacteraemias in Europe: trends from the European Antimicrobial Resistance Surveillance System. Clin. Microbiol. Infect.13, 860–868 (2013).
  • De Kraker E , StewardsonA , HarbarthS. Will 10 million people die a year due to antimicrobial resistance by 2050?PLoS Med.13(11), e1002184 (2016).
  • CLSI . Performance Standards for Antimicrobial Susceptibility Testing. (27th Edition) WayneC (Ed.). Clinical and Laboratory Standards Institute, PA, USA, (2017).
  • Sader S , FlammR , MendesR , FarrellD , JonesR. Antimicrobial activities of ceftaroline and comparator agents against bacterial organisms causing bacteremia in patients with skin and skin structure infections in US medical centers, 2008 to 2014. Antimicrob. Agents Chemother.60(4), 2558–2563 (2016).
  • Marando R , SeniJ , MiramboMet al. Predictors of the extended-spectrum-beta lactamases producing Enterobacteriaceae neonatal sepsis at a tertiary hospital, Tanzania. Int. J. Med. Microbiol.308(7), 803–811 (2018).
  • Ghotaslou R , GhorashiZ , NahaeiM. Klebsiella pneumoniae in neonatal sepsis: a 3-year-study in the pediatric hospital of Tabriz Iran. Jpn J. Infect. Dis.60(2–3), 126–128 (2007).
  • Namikawa H , NikiM , NikiM , YamadaK , NakaieK. Clinical and virulence factors related to the 30-day mortality of Klebsiella pneumoniae bacteremia at a tertiary hospital: a case–control study. Eur. J. Clin. Microbiol. Infect. Dis.38(12), 2291–2297 (2019).
  • Moffa M , GuoW , LiT , CronkR , AbebeL , BartramJ. A systematic review of nosocomial waterborne infections in neonates and mothers. Int. J. Hyg. Environ. Health220(8), 1199–1206 (2017).
  • Bengoechea A , SaPessoa J. Klebsiella pneumoniae infection biology: living to counteract host defences. FEMS Microbiol. Rev.43(2), 123–144 (2019).
  • Gajdács M , BátoriZ , ÁbrókM , LázárA , BuriánK. Characterization of resistance in gram-negative urinary isolates using existing and novel indicators of clinical relevance: a 10-year data analysis. Life10(2), 16 (2020).
  • Iacchini S , SabbatucciM , GagliottiC , RossoliniG , MoroM. Bloodstream infections due to carbapenemase-producing Enterobacteriaceae in Italy: results from nationwide surveillance. Euro. Surveill.24(5), 1800159 (2019).
  • Chiyangi H , MumaB , MalamaSet al. Identification and antimicrobial resistance patterns of bacterial enteropathogens from children aged 0–59 months at the University Teaching Hospital, Lusaka, Zambia: a prospective cross-sectional study. BMC Infect. Dis.17(1), 117 (2017).
  • Chishimba K , Hang'ombeB , MuzanduKet al. Detection of extended-spectrum beta-lactamase-producing Escherichia coli in market-ready chickens in Zambia. Int. J. Microbiol.2016, 1–5 (2016).
  • Zulu A , MatafwaliS , BandaM , MudendaS. Assessment of knowledge, attitude, and practices on antibiotic resistance among undergraduate medical students in the school of medicine at the University of Zambia. Int. J. Basic Clin. Pharmacol.9, 263–270 (2020).
  • Kalungia A , MwambulaH , MunkombweDet al. Antimicrobial stewardship knowledge and perception among physicians and pharmacists at leading tertiary teaching hospitals in Zambia: implications for future policy and practice. J. Chemother.31(7–8), 378–387 (2019).
  • Saleem Z , SaeedH , AhmadMet al. Antibiotic self-prescribing trends, experiences and attitudes in upper respiratory tract infection among pharmacy and non-pharmacy students: a study from Lahore. PLoS ONE11(2), e0149929 (2016).
  • Markovic-Pekovic V , GrubisaN. Self-medication with antibiotics in the Republic of Srpska community pharmacies: pharmacy staff behavior. Pharmacoepidemiol. Drug Saf.21(10), 1130–1133 (2012).
  • Franco BE , AltagraciaMartínez M , SánchezRodríguez MA , WertheimerAI. The determinants of the antibiotic resistance process. Infect. Drug Resist.2, 1–11 (2009).
  • Folgori L , BielickiJ. Advances in pediatric septic shock: future challenges in pediatric and neonatal sepsis: emerging pathogens and antimicrobial resistance. J. Pediatr. Intensive Care8(1), 17–24 (2019).
  • Gajdács M . Epidemiology and antibiotic resistance trends of Pantoea species in a tertiary-care teaching hospital: a 12-year retrospective study. Dev. Health Sci.2(3), 72–75 (2019).
  • Kalonga J , HangomaJ , BandaM , MunkombweD , MudendaS. Antibiotic Prescribing Patterns in Paediatric Patients at Levy Mwanawasa University Teaching Hospital in Lusaka. Int. J. Pharm. Pharmacol.4(1), 138 (2020).
  • Saleem Z , HassaliM , GodmanB , FatimaM , AhmadZ , SajidA. Sale of WHO AWaRe groups antibiotics without a prescription in Pakistan: a simulated client study. J. Pharm. Policy Pract.13, 26 (2020).
  • Sharland M , PulciniC , HarbarthSet al. Classifying antibiotics in the WHO Essential Medicines List for optimal use – be AWaRe. Lancet Infect. Dis.18(1), 18–20 (2018).
  • WHO . WHO Model List of Essential Medicines. (20th Edition). (2017). http://www.who.int/medicines/publications/essentialmedicines/20th_EML2017.pdf?
  • Budd E , CrampE , SharlandMet al. Adaptation of the WHO Essential Medicines List for national antibiotic stewardship policy in England: being AWaRe. J. Antimicrob. Chemother.74(11), 3384–3389 (2019).
  • Hsia Y , LeeB , VersportenA , YangY , BielickiJ , JacksonC. Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries. Lancet Glob. Health7, e861–871 (2019).
  • Johnson A , Muller-PebodyB , BuddE , Ashiru-OredopeD , LadenheimD. Improving feedback of surveillance data on antimicrobial consumption, resistance and stewardship in England: putting the data at your Fingertips. J. Antimicrob. Chemother.72(4), 953–956 (2017).
  • Godman B , HaqueM , MckimmJet al. Ongoing strategies to improve the management of upper respiratory tract infections and reduce inappropriate antibiotic use particularly among lower and middle-income countries: findings and implications for the future. Curr. Med. Res. Opin.36(2), 301–327 (2020).
  • Mudenda S , BangaraF , SitaliJ , BandaM. Knowledge, attitude, and practices on antibiotic resistance among Pharmacists at the University Teaching hospitals in Lusaka, Zambia. J. Harmon. Res. Pharm.8(2), 12–25 (2019).
  • Godman B , FadareJ , KibuuleDet al. Initiatives across countries to reduce antibiotic utilisation and resistance patterns: impact and implications. In: Drug Resistance in Bacteria, Fungi, Malaria, and Cancer.AroraG, SajidA, KaliaVC (Eds). Springer, Cham,Switzerland, 539–576 (2017).
  • Saleem Z , HassaliM , HashmiF. Pakistan’s national action plan for antimicrobial resistance: translating ideas into reality. Lancet Infect. Dis.18(10), 1066–1067 (2018).
  • Gajdács M , PaulikE , SzabóA. Knowledge, attitude and practice of community pharmacists regarding antibiotic use and infectious diseases: a cross-sectional survey in Hungary (KAPPhA-HU). Antibiotics9(2), 41 (2020).
  • Gajdács M . Carbapenem-Resistant but cephalosporin-susceptible Pseudomonas aeruginosa in urinary tract infections: opportunity for colistin sparing. Antibiotics9(4), 153 (2020).

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