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Research article

Assessment of Psychomotor Performance In αCamk-Ii-4R Tau Mice: An Insight Into Human Tauopathies

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Pages 773-783 | Published online: 07 Nov 2012

References

  • Kirschner MW , SuterM, WeingartenMet al. The role of rings in the assembly of microtubules in vitro. Ann. NY Acad. Sci.253, 90–106 (1975).
  • Neve RL , HarrisP, KosikKSet al. Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2. Brain Res.387(3), 271–280 (1986).
  • Goedert M , SpillantiniMG, JakesRet al. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer‘s disease. Neuron3(4), 519–526 (1989).
  • Andreadis A , BrownWM, KosikKS. Structure and novel exons of the human tau gene. Biochemistry31(43), 10626–10633 (1992).
  • Himmler A , DrechselD, KirschnerMWet al. Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains. Mol. Cell. Biol.9(4), 1381–1388 (1989).
  • Spillantini MG , GoedertM. Tau protein pathology in neurodegenerative diseases. Trends Neurosci.21(10), 428–433 (1998).
  • Hirokawa N , ShiomuraY, OkabeS. Tau proteins: the molecular structure and mode of binding on microtubules. J. Cell. Biol.107(4), 1449–1459 (1988).
  • Amos LA . Microtubule structure and its stabilisation. Org. Biomol. Chem.2(15), 2153–2160 (2004).
  • Lindwall G , ColeRD. Phosphorylation affects the ability of tau protein to promote microtubule assembly. J. Biol. Chem.259(8), 5301–5305 (1984).
  • Hutton M , LendonCL, RizzuPet al. Association of missense and 5‘-splice-site mutations in tau with the inherited dementia FTDP-17. Nature393(6686), 702–705 (1998).
  • Poorkaj P , BirdTD, WijsmanEet al. Tau is a candidate gene for chromosome 17 frontotemporal dementia. Ann. Neurol.43(6), 815–825 (1998).
  • Spillantini MG , MurrellJR, GoedertMet al. Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proc. Natl Acad. Sci. USA95(13), 7737–7741 (1998).
  • Kovacs GG , MajtenyiK, SpinaSet al. White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration. J. Neuropathol. Exp. Neurol.67(10), 963–975 (2008).
  • Kumaran R , KingsburyA, CoulterIet al. DJ-1 (PARK7) is associated with 3R and 4R tau neuronal and glial inclusions in neurodegenerative disorders. Neurobiol. Dis.28(1), 122–132 (2007).
  • Alonso A , ZaidiT, NovakMet al. Interaction of tau isoforms with Alzheimer‘s disease abnormally hyperphosphorylated tau and in vitro phosphorylation into the disease-like protein. J. Biol. Chem.276(41), 37967–37973 (2001).
  • Gotz J , StrefferJR, DavidDet al. Transgenic animal models of Alzheimer‘s disease and related disorders: histopathology, behavior and therapy. Mol. Psychiatr.9(7), 664–683 (2004).
  • Gotz J , ChenF, BarmettlerRet al. Tau filament formation in transgenic mice expressing P301L tau. J. Biol. Chem.276(1), 529–534 (2001).
  • Gotz J , ChenF, van DorpeJet al. Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Aβ 42 fibrils. Science293(5534), 1491–1495 (2001).
  • Andorfer C , KressMY, Espinozaet al. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J. Neurochem.86(3), 582–590 (2003).
  • Sennvik K , BoekhoornK, LasradoRet al. Tau-4R suppresses proliferation and promotes neuronal differentiation in the hippocampus of tau knockin/knockout mice. FASEB J.21(9), 2149–2161 (2007).
  • Tatebayashi Y , MiyasakaT, ChuiDHet al. Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau. Proc. Natl Acad. Sci. USA99(21), 13896–13901 (2002).
  • Makimura H , MizunoTM, IsodaFet al. Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression. BMC Physiol.3, 5 (2003).
  • Tanemura K , AkagiT, MurayamaMet al. Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau. Neurobiol. Dis.8(6), 1036–1045 (2001).
  • Tanemura K , MurayamaM, AkagiTet al. Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau. J. Neurosci.22(1), 133–141 (2002).
  • Mayford M , WangJ, KandelERet al. CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP. Cell81(6), 891–904 (1995).
  • Tabuse M , YaguchiM, OhtaSet al. A simple behavioral test for locomotor function after brain injury in mice. J. Clin. Neurosci.17(11), 1412–1416 (2010).
  • Komada M , TakaoK, MiyakawaT. Elevated plus maze for mice. J. Vis. Exp. (22), 1088 (2008).
  • Takao K , MiyakawaT. Light/dark transition test for mice. J. Vis. Exp.13(1), 104 (2006).
  • Matsuo N , TakaoK, NakanishiKet al. Behavioral profiles of three C57BL/6 substrains. Front. Behav. Neurosci.4, 29 (2010).
  • Lewis J , McGowanE, RockwoodJet al. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat. Genet.25(4), 402–405 (2000).
  • Zomkowski AD , HammesL, LinJet al. Agmatine produces antidepressant-like effects in two models of depression in mice. Neuroreport13(4), 387–391 (2002).
  • Shiryaev N , JouroukhinY, GozesI. 3R tau expression modifies behavior in transgenic mice. J. Neurosci. Res.88(12), 2727–2735 (2010).
  • Ott BR . Cognition and behavior in patients with Alzheimer‘s disease. J. Gend. Specif. Med.2(3), 63–69 (1999).
  • Gozes I . Microtubules (tau) as an emerging therapeutic target: NAP (davunetide). Curr. Pharm. Des.17(31), 3413–3417 (2011).

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