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Editorial

Unraveling the Pathophysiology of Chronic Stroke Lesions Could Yield Treatments for Stroke-Related Dementia

Pages 1-4 | Received 30 Nov 2015, Accepted 08 Dec 2015, Published online: 11 Jan 2016

References

  • Strokecenter.org. www.strokecenter.org/patients/about-stroke/stroke-statistics/.
  • Doyle KP , SimonRP, Stenzel-PooreMP. Mechanisms of ischemic brain damage. Neuropharmacology55(3), 310–318 (2008).
  • Doyle KP , QuachLN, SoleMet al. B-lymphocyte-mediated delayed cognitive impairment following stroke. J. Neurosci.35(5), 2133–2145 (2015).
  • Yang J , D'EsterreC, CerutiSet al. Temporal changes in blood–brain barrier permeability and cerebral perfusion in lacunar/subcortical ischemic stroke. BMC Neurol.15, 214 (2015).
  • Rosenberg GA . Neurological diseases in relation to the blood–brain barrier. J. Cereb. Blood Flow Metab.32(7), 1139–1151 (2012).
  • Seghier ML , RamsdenS, LimL, LeffAP, PriceCJ. Gradual lesion expansion and brain shrinkage years after stroke. Stroke45(3), 877–879 (2014).
  • Gupta A , WatkinsA, ThomasPet al. Coagulation and inflammatory markers in Alzheimer's and vascular dementia. Int. J. Clin. Pract.59(1), 52–57 (2005).
  • Levin EC , AcharyaNK, HanMet al. Brain-reactive autoantibodies are nearly ubiquitous in human sera and may be linked to pathology in the context of blood–brain barrier breakdown. Brain Res.1345, 221–232 (2010).
  • Simone MJ , TanZS. The role of inflammation in the pathogenesis of delirium and dementia in older adults: a review. CNS Neurosci. Ther.17(5), 506–513 (2011).
  • Roman GC , ErkinjunttiT, WallinA, PantoniL, ChuiHC. Subcortical ischaemic vascular dementia. Lancet Neurol.1(7), 426–436 (2002).
  • Troncoso JC , ZondermanAB, ResnickSM, CrainB, PletnikovaO, O'BrienRJ. Effect of infarcts on dementia in the Baltimore longitudinal study of aging. Ann. Neurol.64(2), 168–176 (2008).
  • Barba R , Martinez-EspinosaS, Rodriguez-GarciaE, PondalM, VivancosJ, Del SerT. Poststroke dementia: clinical features and risk factors. Stroke31(7), 1494–1501 (2000).
  • Gorelick PB , ScuteriA, BlackSEet al. Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke42(9), 2672–2713 (2011).
  • Savva GM , StephanBC. Epidemiological studies of the effect of stroke on incident dementia: a systematic review. Stroke41(1), e41–e46 (2010).
  • Leys D , HenonH, Mackowiak-CordolianiMA, PasquierF. Poststroke dementia. Lancet Neurol.4(11), 752–759 (2005).
  • Ivan CS , SeshadriS, BeiserAet al. Dementia after stroke: the Framingham Study. Stroke35(6), 1264–1268 (2004).
  • Yu SW , FriedmanB, ChengQ, LydenPD. Stroke-evoked angiogenesis results in a transient population of microvessels. J. Cereb. Blood Flow Metab.27(4), 755–763 (2007).
  • Orth M , BellostaS. Cholesterol: its regulation and role in central nervous system disorders. Cholesterol2012(2012), 292598 (2012).
  • Lech M , AndersHJ. Macrophages and fibrosis: how resident and infiltrating mononuclear phagocytes orchestrate all phases of tissue injury and repair. Biochim. Biophys. Acta1832(7), 989–997 (2013).
  • Wang X , CaoK, SunXet al. Macrophages in spinal cord injury: phenotypic and functional change from exposure to myelin debris. Glia63(4), 635–651 (2015).

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