Potential Utility of Peptides Against Damage Induced by Ionizing Radiation

References

• Bray F , FerlayJ, SoerjomataramIet al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin.68, 394–424 (2018).
   PubMed Web of Science ®Google Scholar
• Yaromina A , KrauseM, BaumannM. Individualization of cancer treatment from radiotherapy perspective. Mol. Oncol.6, 211–221 (2012).
   PubMed Web of Science ®Google Scholar
• Citrin D , CotrimAP, HyodoFet al. Radioprotectors and mitigators of radiation-induced normal tissue injury. Oncologist.15(4), 360–371 (2010).
   PubMed Web of Science ®Google Scholar
• Patel VN , GuptaS, ShareefMM, AhmedMM. Contemporary radiation countermeasure. Defence Sci. J.61(2), 138–145 (2011).
   Web of Science ®Google Scholar
• Stone HB , MoulderJE, ColemanCNet al. Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3–4, 2003. Radiat. Res.162(6), 711–28 (2004).
   PubMed Web of Science ®Google Scholar
• Kamran MZ , RanjanA, KaurNet al. Radioprotective agents: strategies and translational advances. Med. Res. Rev.36(3), 461–493 (2016).
   PubMed Web of Science ®Google Scholar
• Singh VK , NewmanVL, RomainePLet al. Radiation countermeasure agents:anupdate (2011–2014). Expert Opin. Ther. Pat.24(11), 1229–1255 (2014).
   PubMed Web of Science ®Google Scholar
• Fields K , FallaTJ, RodanK, BushL. Bioactive peptides: signaling the future. J. Cosmet. Dermatol.8(1), 8–13 (2009).
   PubMed Web of Science ®Google Scholar
• Pai VV , BhandariP, ShuklaP. Topical peptides as cosmeceuticals. Indian J. Dermatol. Venereol. Leprol.83(1), 9–18 (2017).
   PubMed Web of Science ®Google Scholar
• Groß A , HashimotoC, StichtH, EichlerJ. Synthetic peptides as protein. Front. Bioeng. Biotechnol.19(3), 211 (2016).
   Google Scholar
• Painuli S , KumarN. Prospects in the development of natural radioprotective therapeutics with anti-cancer properties from the plants of Uttarakhand region of India. J. Ayurveda Integr. Med.7(1), 62–68 (2016).
   PubMed Web of Science ®Google Scholar
• Singh VK , PollardHB. Patents for toll-like receptor ligands as radiation countermeasure for acute radiation syndrome. Expert Opin. Ther. Pat.25(10), 1085–1092 (2015).
   PubMed Web of Science ®Google Scholar
• Hosseinimehr SJ . Trends in the development of radioprotective agents. Drug Discov. Today.12(19–20), 794–805 (2007).
   PubMed Web of Science ®Google Scholar
• Asghari M , ShaghaghiZ, FarzipourS, HosseinimehrSJ. Radioprotective effect of olanzapine as an anti-psychotic drug against genotoxicity and apoptosis induced by ionizing radiation on human lymphocytes. Mol. Biol. Rep.46, 5909–5917 (2019).
   PubMed Web of Science ®Google Scholar
• Pouri M , ShaghaghiZ, GhasemiA, HosseinimehrSJ. Radioprotective effect of gliclazide as an anti-hyperglycemic agent against genotoxicity induced by ionizing radiation on human lymphocytes. Cardiovasc. Hematol. Agents Med. Chem.17(1), 40–46 (2019).
   PubMedGoogle Scholar
• Jagetia GC . Radioprtective potential of plants and herbs against the effects of ionizing radiation. J. Clin. Biochem. Nutr.40(2), 74–81 (2007).
   PubMed Web of Science ®Google Scholar
• Naeimi A , AbbasspourS, TorabizadehSA. The first and low cost copper Schiff base/manganese oxide bio nanocomposite from unwanted plants as a robust industrial catalyst. Artif. Cells Nanomed. Biotechnol.48(1), 560–571 (2020).
   PubMed Web of Science ®Google Scholar
• Torabizadeh SA , RezaeifarM, JomehzadehAet al. Radioprotective potential of sulindac sulfide to prevent DNA damage due to ionizing radiation. Drug Des. Devel. Ther.6(13), 4127–4134 (2019).
   Google Scholar
• Burdelya LG , KrivokrysenkoVI, TallantTCet al. An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models. Science.320(5873), 226–230 (2008).
   PubMed Web of Science ®Google Scholar
• Rodemann HP , DittmannK, GüvenN, MayerC. Peptide with radio protective effect. US6645934B1 (2003).
   Google Scholar
• Wang ZD , QiaoYL, TianXFet al. Toll-like receptor 5 agonism protects mice from radiation pneumonitis and pulmonary fibrosis. Asian Pac. J. Cancer Prev.13(9), 4763–4767 (2012).
   PubMedGoogle Scholar
• McConnell KW , MuenzerJT, ChangKCet al. Anti-apoptotic peptides protect against radiation-induced cell death. Biochem. Biophys. Res. Commun.355(2), 501–507 (2007).
   PubMed Web of Science ®Google Scholar
• Kanai A , ZabbarovaI, AmoscatoAet al. Mitochondrial targeting of radioprotectants using peptidyl conjugates. Org. Biomol. Chem.5(2), 307–309 (2007).
   PubMed Web of Science ®Google Scholar
• Macias CA , ChiaoJW, XiaoJet al. Treatment with a novel hemigramicidin-TEMPO conjugate prolongs survival in a rat model of lethal hemorrhagic shock. Ann. Surg.245(2), 305–314 (2007).
   PubMed Web of Science ®Google Scholar
• Wipf P , XiaoJ, JiangJet al. Mitochondrial targeting of selective electron scavengers: synthesis and biological analysis of hemigramicidin-TEMPO Conjugates. J. Am. Chem. Soc.127(36), 12460–12461 (2005).
   PubMed Web of Science ®Google Scholar
• Kagan VE , WipfP, StoyanovskyDet al. Mitochondrial targeting of electron scavenging antioxidants: regulation of selective oxidation vs random chain reactions. Adv. Drug Deliv. Rev.61(14), 1375–1385 (2009).
   PubMed Web of Science ®Google Scholar
• Zhao K , ZhaoGM, DunliWUet al. Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury. J. Biol. Chem.279(33), 34682–34690 (2004).
   PubMed Web of Science ®Google Scholar
• Rocha M , Hernandez-MijaresA, Garcia-MalpartidaKet al. Mitochondria-targeted antioxidant peptides. Curr. Pharm. Des.16(28), 3124–3131 (2010).
   PubMed Web of Science ®Google Scholar
• Szeto HH . Cell-permeable, mitochondrial-targeted, peptide antioxidants. AAPS J.8(2), 277–283 (2006).
   PubMed Web of Science ®Google Scholar
• Dittmann KH , GuevenN, MayerC, RodemannHP. Characterization of the amino acids essential for the photo- and radioprotective effects of a Bowman–Birk protease inhibitor-derived nonapeptide. Protein Eng.14(3), 157–160 (2001).
   PubMedGoogle Scholar
• Odani S , IkenakaT. Studies on soybean trypsin inhibitors: XIII. Preparation and characterization of active fragments from Bowman–Birk proteinase inhibitor1. J. Biochem.83(3), 747–53 (1987).
   Google Scholar
• Gueven N , DittmannK, MayerC, RodemannHP. The radioprotective potential of the Bowman–Birk protease inhibitor is independent of its secondary structure. Cancer Lett.125(1–2), 77–82 (1998).
   PubMed Web of Science ®Google Scholar
• Dittmann K , LöfflerH, BambergM, RodemanHP. Bowman–Birk proteinase inhibitor (BBI) modulates radiosensitivity and radiation-induced differentiation of human fibroblasts in culture. Radiother. Oncol.34(2), 137–143 (1995).
   PubMed Web of Science ®Google Scholar
• Dittmann K , Virsik-KoppP, MayerCet al. Bowman–Birk protease inhibitor activates DNA-dependent protein kinase and reduces formation of radiation-induced dicentric chromosomes. Int. J. Radiat. Biol.79(10), 801–808 (2003).
   PubMed Web of Science ®Google Scholar
• Chen YW , HuangSC, Lin-ShiauSY, LinJK. Bowman–Birk inhibitor abates proteasome function and suppresses the proliferation of MCF7 breast cancer cells through accumulation of MAP kinase phosphatase-1. Carcinogenesis26(7), 1296–1306 (2005).
   PubMed Web of Science ®Google Scholar
• Jiang J , ABelikovaN, HoyeATet al. A mitochondria-targeted nitroxide/hemigramicidin S conjugate protects mouse embryonic cells against gamma irradiation. Int. J. Radiat. Oncol. Biol. Phys.70(3), 816–825 (2008).
   PubMed Web of Science ®Google Scholar
• Epperly MW , PierceJG, DixonTet al. The mitochondrial targeted GS-nitroxide JP4-039 is radioprotective in vitro and in vivo. Int. J. Radiat. Oncol. Biol. Phys.72(1), S82 (2008).
   Web of Science ®Google Scholar
• Dumont F , LeRoux A, BischoffP. Radiation countermeasure agents: an update. Expert Opin. Ther. Pat.20(1), 73–101 (2010).
   PubMed Web of Science ®Google Scholar
• Szeto HH . First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics. Br. J. Pharmacol.171(8), 2029–2050 (2014).
   PubMed Web of Science ®Google Scholar
• Wang C , ZhouM, LiTet al. Effects of scorpion venom peptide B5 on hematopoietic recovery in irradiated mice and the primary mechanisms. Sci. Rep.5, 153–163 (2015).
   Web of Science ®Google Scholar
• Wang Y , XingB, LiTet al. SVP-B5 peptide from Buthus martensii Karsch scorpion venom exerts hyperproliferative effects on irradiated hematopoietic cells. Exp. Ther. Med.14(5), 5081–5086 (2017).
   PubMed Web of Science ®Google Scholar
• McDunn JE , MuenzerJT, DunneBet al. An anti-apoptotic peptide improves survival in lethal total body irradiation. Biochem. Biophys. Res. Commun.382(4), 657–662 (2009).
   PubMed Web of Science ®Google Scholar
• Alfieri AA , LiuL, BhanjaP, HarsanyiZ. Therapeutic protection of radiation-induced whole body damage by the small soluble peptide, EA230. Int. J. Radiat. Oncol. Biol. Phys.69, S125–S126 (2007).
   PubMed Web of Science ®Google Scholar
• Norfleet AM , BergmannJS, CarneyDH. Thrombin peptide, TP508, stimulates angiogenic responses in animal models of dermal wound healing, in chick chorioallantoic membranes, and in cultured human aortic and microvascular endothelial cells. Gen. Pharmacol.35(5), 249–54 (2000).
   PubMedGoogle Scholar
• Ryaby JT , ShellerMR, LevineBPet al. Thrombin peptide TP508 stimulates cellular events leading to angiogenesis, revascularization, and repair of dermal and musculoskeletal tissues. J. Bone Joint Surg. Am.88(3), 132–139 (2006).
   PubMedGoogle Scholar
• Kantara C , MoyaSM, HouchenCWet al. Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity. Lab. Invest.95(11), 1222–1233 (2015).
   PubMed Web of Science ®Google Scholar
• Olszewska-Pazdrak B , McVicarSD, RayavaraKet al. Nuclear countermeasure activity of TP508 linked to restoration of endothelial function and acceleration of DNA repair. Radiat. Res.186(2), 162–174 (2016).
   PubMed Web of Science ®Google Scholar
• Burdelya LG , BrackettCM, KojouharovBet al. Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist. Proc. Natl. Acad. Sci. USA110(20), 1857–1866 (2013).
   PubMed Web of Science ®Google Scholar
• Liu Z , LeiX, LiXE, CaiJMet al. Toll-like receptors and radiation protection. Eur. Rev. Med. Pharmacol. Sci.22(1), 31–39 (2018).
   PubMed Web of Science ®Google Scholar
• Burdelya LG , GleibermanAS, ToshkovIet al. Toll-like receptor 5 agonist protects mice from dermatitis and oral mucositis caused by local radiation: implications for head-and-neck cancer radiotherapy. Int. J. Radiat. Oncol. Biol. Phys.83(1), 228–34 (2012).
   PubMed Web of Science ®Google Scholar
• Shakhov AN , SinghVK, BoneFet al. Prevention and mitigation of acute radiation syndrome in mice by synthetic lipopeptide agonists of toll-like receptor 2 (TLR2). PLoS ONE.7(3), e33044 (2012).
   PubMed Web of Science ®Google Scholar
• Singh VK , DuceyEJ, FatanmiOOet al. CBLB613: a TLR 2/6 agonist, natural lipopeptide of Mycoplasma arginini, as a novel radiation countermeasure. Radiat. Res.177(5), 628–642 (2012).
   PubMed Web of Science ®Google Scholar
• Arunachalam KD , ArunachalamAM, JayakrishnaKet al. Radioprotective properties of casein phospho peptides (CPP) in gamma irradiated animal models. Natl. Symp. Radiat. Phys.44(30), 290–292 (2012).
   Google Scholar
• Chen W , ShinKH, KimSet al. hTERT peptide fragment GV1001 demonstrates radioprotective and antifibrotic effects through suppression of TGFbeta signaling. Int. J. Mol. Med.41(6), 3211–3220 (2018).
   PubMed Web of Science ®Google Scholar
• Zhu NA , LiuRui, HeLXet al. Radioprotective effect of walnut oligopeptides against gamma radiation-induced splenocyte apoptosis and intestinal injury in mice. Molecules24(8), 1582 (2019).
   PubMed Web of Science ®Google Scholar
• Berlett BS , LevineRL. Designing antioxidant peptides. Redox. Rep.19(2), 80–86 (2014).
   PubMed Web of Science ®Google Scholar
• Varanda EA , TavaresDC. Radioprotection: mechanism and radioprotective agents including honeybee venom. J. Venom. Anim. Toxins.4(1), 5–21 (1998).
   Google Scholar
• Peck ML , O'ConnorR, JohnsonTJet al. Radioprotective potential and chelating properties of glycylhistamine, an analog of histamine terminal peptides found in bee venom. Toxicon.16(6), 690–694 (1978).
   PubMed Web of Science ®Google Scholar
• Peck ML , O'ConnorR. Procamine and other basic peptides in the venom of the honeybee (Apis mellifera). J. Agric. Food Chem.22(1), 51–53 (1974).
   PubMed Web of Science ®Google Scholar
• Ginsberg NJ , DauerM, SlottaKH. Melittin used as a protective agent against X-irradiation. Nature1334 (1968).
   PubMed Web of Science ®Google Scholar
• Shaghaghi Z , AbediSM, HoeeeinimehrSJ. 99mTc-HYNIC-(Ser)3-J18 peptide: a radiotracer for non-small-cell lung cancer targeting. Chem. Biol. Drug Des.92(1), 1214–1220 (2018).
   PubMed Web of Science ®Google Scholar