313
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Real-world outcomes of systemic therapy in locally advanced, recurrent or metastatic cutaneous squamous cell carcinoma

, , , , , , , & ORCID Icon show all
Pages 2087-2099 | Received 28 Sep 2021, Accepted 16 Feb 2022, Published online: 04 Mar 2022

References

  • Rogers HW , WeinstockMA, FeldmanSR, ColdironBM. Incidence estimate of nonmelanoma skin cancer (keratinocyte carcinomas) in the U.S. population, 2012. JAMA Dermatol.151(10), 1081–1086 (2015).
  • Burton KA , AshackKA, KhachemouneA. Cutaneous squamous cell carcinoma: a review of high-risk and metastatic disease. Am. J. Clin. Dermatol.17(5), 491–508 (2016).
  • Karia PS , HanJ, SchmultsCD. Cutaneous squamous cell carcinoma: estimated incidence of disease, nodal metastasis, and deaths from disease in the United States, 2012. J. Am. Acad. Dermatol.68(6), 957–966 (2013).
  • Karia PS . Epidemiology and outcomes of cutaneous squamous cell carcinoma. In: High-Risk Cutaneous Squamous Cell Carcinoma.Springer-Verlag, Heidelberg, Germany (2016).
  • National Comprehensive Cancer Network . Clinical practice guidelines in oncology: squamous cell skin cancer. Version 2 (2021). www.nccn.org/professionals/physician_gls/pdf/squamous.pdf
  • US FDA . FDA approves cemiplimab-rwlc for metastatic or locally advanced cutaneous squamous cell carcinoma (2019). www.fda.gov/drugs/drug-approvals-and-databases/fda-approves-cemiplimab-rwlc-metastatic-or-locally-advanced-cutaneous-squamous-cell-carcinoma
  • Migden MR , RischinD, SchmultsCDet al. PD-1 blockade with cemiplimab in advanced cutaneous squamous-cell carcinoma. N. Engl. J. Med.379(4), 341–351 (2018).
  • US FDA . FDA approves pembrolizumab for cutaneous squamous cell carcinoma (2020). www.fda.gov/drugs/drug-approvals-and-databases/fda-approves-pembrolizumab-cutaneous-squamous-cell-carcinoma
  • Grob JJ , GonzalezR, Basset-SeguinNet al. Pembrolizumab monotherapy for recurrent or metastatic cutaneous squamous cell carcinoma: a single-arm phase II trial (KEYNOTE-629). J. Clin. Oncol.38(25), 2916–2925 (2020).
  • Eisenhauer EA , TherasseP, BogaertsJet al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur. J. Cancer45(2), 228–247 (2009).
  • Ma X , BellomoL, MageeKet al. Characterization of a real-world response variable and comparison with RECIST-based response rates from clinical trials in advanced NSCLC. Adv. Ther.38(4), 1843–1859 (2021).
  • The US Oncology Network. Empowering local cancer care(2022). www.usoncology.com/our-company
  • Khozin S , MiksadRA, AdamiJet al. Real-world progression, treatment, and survival outcomes during rapid adoption of immunotherapy for advanced non-small cell lung cancer. Cancer125(22), 4019–4032 (2019).
  • Feinberg BA , BharmalM, KlinkAJ, NabhanC, PhatakH. Using Response Evaluation Criteria in Solid Tumors in real-world evidence cancer research. Future Oncol.14(27), 2841–2848 (2018).
  • Friends of Cancer Research . Establishing a framework to evaluate real-world endpoints (2018). https://friendsofcancerresearch.org/publications/establishing-framework-evaluate-real-world-endpoints
  • Hillen U , LeiterU, HaaseSet al. Advanced cutaneous squamous cell carcinoma: a retrospective analysis of patient profiles and treatment patterns – results of a non-interventional study of the DeCOG. Eur. J. Cancer96, 34–43 (2018).
  • JarkowskiA3rd , HareR, LoudPet al. Systemic therapy in advanced cutaneous squamous cell carcinoma (CSCC): the Roswell Park experience and a review of the literature. Am. J. Clin. Oncol.39(6), 545–548 (2016).
  • Maubec E , PetrowP, Scheer-SenyarichIet al. Phase II study of cetuximab as first-line single-drug therapy in patients with unresectable squamous cell carcinoma of the skin. J. Clin. Oncol.29(25), 3419–3426 (2011).
  • Cowey CL , RobertNJ, EspiritoJLet al. Clinical outcomes among unresectable, locally advanced, and metastatic cutaneous squamous cell carcinoma patients treated with systemic therapy. Cancer Med.9(20), 7381–7387 (2020).
  • Walker B , BoydM, AguilarKet al. Comparisons of real-world time-to-event end points in oncology research. JCO Clin. Cancer Inform.5, 45–46 (2021).
  • Huang Bartlett C , MardekianJ, CotterMJet al. Concordance of real-world versus conventional progression-free survival from a phase 3 trial of endocrine therapy as first-line treatment for metastatic breast cancer. PLoS ONE15(4), e0227256 (2020).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.