Sentinel Lymph Node Detection in Thyroid Carcinoma Using ⁶⁸Ga-Tilmanocept PET/CT: A Proof-of-Concept Study Protocol

References

• Durante C , HaddyN, BaudinEet al. Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma: benefits and limits of radioiodine therapy. J. Clin. Endocrinol. Metab.91(8), 2892–2899 (2006).
   PubMed Web of Science ®Google Scholar
• Haugen BR , AlexanderEK, BibleKCet al. 2015 American Thyroid Association Management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer. Thyroid26(1), 1–133 (2016).
   PubMed Web of Science ®Google Scholar
• Shah MH , GoldnerWS, BensonABet al. Neuroendocrine and adrenal tumors, version 2.2021. J. Natl Compr. Canc. Netw.19(7), 839–868 (2021).
   PubMedGoogle Scholar
• Van Nostrand D . The benefits and risks of I-131 therapy in patients with well-differentiated thyroid cancer. Thyroid19(12), 1381–1391 (2009).
   PubMed Web of Science ®Google Scholar
• Mallick U , HarmerC, HackshawA. The HiLo trial: a multicentre randomised trial of high- versus low-dose radioiodine, with or without recombinant human thyroid stimulating hormone, for remnant ablation after surgery for differentiated thyroid cancer. Clin. Oncol.20(5), 325–326 (2008).
   PubMed Web of Science ®Google Scholar
• Schlumberger M , BogdanC, BorgetIet al. Strategies of radioiodine ablation in patients with low-risk thyroid cancer. N. Engl. J. Med.366(18), 1663–1673 (2012).
   PubMed Web of Science ®Google Scholar
• Schlumberger M , LeboulleuxS, CatargiBet al. Outcome after ablation in patients with low-risk thyroid cancer (ESTIMABL1): 5-year follow-up results of a randomised, phase 3, equivalence trial. Lancet Diabetes Endocrinol.6(8), 618–626 (2018).
   PubMed Web of Science ®Google Scholar
• Mallick U , HarmerC, HackshawA, MossL. Iodine or not (IoN) for low-risk differentiated thyroid cancer: the next UK National Cancer Research Network randomised trial following HiLo. Clin. Oncol.24(3), 159–161 (2012).
   PubMed Web of Science ®Google Scholar
• Cakir M , GrossmanAB. At the cutting edge. Medullary thyroid cancer: molecular biology and novel molecular therapies. Neuroendocrinology90(4), 323–348 (2009).
   PubMed Web of Science ®Google Scholar
• Kebebew E , ItuartePHG, SipersteinAE, DuhQ-Y, ClarkOH. Medullary thyroid carcinoma. Clinical characteristics, treatment, prognostic factors, and a comparison of staging systems. Cancer88(5), 1139–1148 (2000).
   PubMed Web of Science ®Google Scholar
• Wells SA , AsaSL, DralleHet al. Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma. Thyroid25(6), 567–610 (2015).
   PubMed Web of Science ®Google Scholar
• Meijer JAA , BakkerLEH, ValkGDet al. Radioactive iodine in the treatment of medullary thyroid carcinoma: a controlled multicenter study. Eur. J. Endocrinol.168(5), 779–786 (2013).
   PubMed Web of Science ®Google Scholar
• van Beek D-J , AlmquistM, BergenfelzAOet al. Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE® databases. Br. J. Surg.108(6), 691–701 (2020).
   Web of Science ®Google Scholar
• Scollo C , BaudinE, TravagliJ-PTet al. Rationale for central and bilateral lymph node dissection in sporadic and hereditary medullary thyroid cancer. J. Clin. Endocrinol. Metab.88(5), 2070–2075 (2003).
   PubMed Web of Science ®Google Scholar
• Kuo EJ , ShoS, LiN, ZanoccoKA, YehMW, LivhitsMJ. Risk factors associated with reoperation and disease-specific mortality in patients with medullary thyroid carcinoma. JAMA Surg.153(1), 52–59 (2018).
   PubMed Web of Science ®Google Scholar
• Schilling C , StoeckliSJ, VigiliMGet al. Surgical consensus guidelines on sentinel node biopsy (SNB) in patients with oral cancer. Head Neck41(8), 2655–2664 (2019).
   PubMed Web of Science ®Google Scholar
• Albers MB , NordenströmE, WohlfahrtJ, BergenfelzA, AlmquistM. Sentinel lymph node biopsy in thyroid cancer. World J. Surg.44(1), 142–147 (2020).
   PubMed Web of Science ®Google Scholar
• Puccini M , MancaG, NeriCMet al. Effect of sentinel node biopsy in clinically N0, BRAF V600E-mutated, small papillary thyroid carcinoma: a pilot study. Clin. Nucl. Med.44(5), 359–364 (2019).
   PubMed Web of Science ®Google Scholar
• Garau LM , RubelloD, MorgantiRet al. Sentinel lymph node biopsy in small papillary thyroid cancer: a meta-analysis. Clin. Nucl. Med.44(2), 108–118 (2019).
   Web of Science ®Google Scholar
• González Ó , ZafonC, CaubetEet al. Selective sentinel lymph node biopsy in papillary thyroid carcinoma in patients with no preoperative evidence of lymph node metastasis. Endocrinol. Diabetes Nutr.64(8), 451–455 (2017).
   PubMed Web of Science ®Google Scholar
• Pelizzo MR , ToniatoA, SorgatoNet al. 99Tc nanocolloid sentinel node procedure in papillary thyroid carcinoma: our mono-institutional experience on a large series of patients. Acta Otorhinolaryngol. Ital.29(6), 321–325 (2009).
   PubMed Web of Science ®Google Scholar
• Lee SK , ChoiJH, LimHIet al. Sentinel lymph node biopsy in papillary thyroid cancer: comparison study of blue dye method and combined radioisotope and blue dye method in papillary thyroid cancer. Eur. J. Surg. Oncol.35(9), 974–979 (2009).
   PubMed Web of Science ®Google Scholar
• Jozaghi Y , RichardsonK, AnandSet al. Frozen section analysis and sentinel lymph node biopsy in well differentiated thyroid cancer. J. Otolaryngol. Head Neck Surg.42(Sep), (2013).
   PubMedGoogle Scholar
• Puccini M , MancaG, UgoliniCet al. Interest of sentinel node biopsy in apparently intrathyroidal medullary thyroid cancer: a pilot study. J. Endocrinol. Invest.37(9), 829–834 (2014).
   PubMed Web of Science ®Google Scholar
• Boni G , MazzarriS, GrossoMet al. Sentinel node radioguided biopsy in surgical management of the medullary thyroid carcinoma a case report. Ann. Ital. Chir.85(ePub), 1–4 (2014).
   PubMedGoogle Scholar
• Kim MJ , BackK, ChoeJ-H, KimJ-H, KimJS. Feasibility of lateral sentinel lymph node biopsy in medullary thyroid cancer: surrogate tool for determining prophylactic lateral neck dissection – a pilot study. Head Neck43(11), 3276–3286 (2021).
   PubMed Web of Science ®Google Scholar
• Bluemel C , RubelloD, CollettiPM, de BreeR, HerrmannK. Sentinel lymph node biopsy in oral and oropharyngeal squamous cell carcinoma: current status and unresolved challenges. Eur. J. Nucl. Med. Mol. Imaging42(9), 1469–1480 (2015).
   PubMed Web of Science ®Google Scholar
• de Bree R , TakesRP, ShahJPet al. Elective neck dissection in oral squamous cell carcinoma: past, present and future. Oral Oncol.90, 87–93 (2019).
   PubMed Web of Science ®Google Scholar
• Zhang X , ShenY-P, LiJ-G, ChenG. Clinical feasibility of imaging with indocyanine green combined with carbon nanoparticles for sentinel lymph node identification in papillary thyroid microcarcinoma. Medicine (Baltimore)98(36), 1–6 (2019).
   Web of Science ®Google Scholar
• Ahmed M , PurushothamAD, DouekM. Novel techniques for sentinel lymph node biopsy in breast cancer: a systematic review. Lancet Oncol.15(8), e351–e362 (2014).
   PubMed Web of Science ®Google Scholar
• den Toom IJ , MahieuR, van RooijRet al. Sentinel lymph node detection in oral cancer: a within-patient comparison between [99mTc]Tc-tilmanocept and [99mTc]Tc-nanocolloid. Eur. J. Nucl. Med. Mol. Imaging48(3), 851–858 (2021).
   PubMed Web of Science ®Google Scholar
• Kasbollah A , EuP, CowellS, DebP. Review on production of 89Zr in a medical cyclotron for PET radiopharmaceuticals. J. Nucl. Med. Technol.41(1), 35–41 (2013).
   PubMedGoogle Scholar
• Martiniova L , DePalatis L, EtchebehereE, RavizziniG. Gallium-68 in medical imaging. Curr. Radiopharm.9(3), 187–207 (2016).
   PubMedGoogle Scholar
• Anderson KM , BarbackCV, QinZet al. Molecular imaging of endometrial sentinel lymph nodes utilizing fluorescent-labeled tilmanocept during robotic-assisted surgery in a porcine model. PLOS ONE13(7), 1–13 (2018).
   Web of Science ®Google Scholar
• Qin Z , HohCK, HallDJ, VeraDR. A tri-modal molecular imaging agent for sentinel lymph node mapping. Nucl. Med. Biol.42(12), 917–922 (2015).
   PubMed Web of Science ®Google Scholar
• Stroup SP , KaneCJ, Farchshchi-HeydariSet al. Preoperative sentinel lymph node mapping of the prostate using PET/CT fusion imaging and Ga-68-labeled tilmanocept in an animal model. Clin. Exp. Metastasis29(7), 673–680 (2012).
   PubMed Web of Science ®Google Scholar
• Mahieu R , KrijgerGC, VerversFFTTet al. [68Ga]Ga-tilmanocept PET/CT lymphoscintigraphy: a novel technique for sentinel lymph node imaging. Eur. J. Nucl. Med. Mol. Imaging48(4), 963–965 (2021).
   PubMed Web of Science ®Google Scholar
• Mahieu R , KrijgerGC, VerversFFTTet al. [68Ga]Ga-tilmanocept PET/CT lymphoscintigraphy for sentinel lymph node detection in early-stage oral cavity carcinoma. Eur. J. Nucl. Med. Mol. Imaging48, 3–4 (2020).
   PubMed Web of Science ®Google Scholar