Young age is associated with inferior outcomes in early-stage luminal B breast cancer patients who undergo mastectomy

References

• WHO . Globocan 2020 Global Cancer Observatory. World Health Organization. http://gco.iarc.fr
   Google Scholar
• Chen W , ZhengR, BaadePDet al. Cancer statistics in China, 2015. CA Cancer J. Clin.66(2), 115–132 (2015).
   Web of Science ®Google Scholar
• Assi HA , KhouryKE, DboukH, KhalilLE, MouhieddineTH, ElSaghir NS. Epidemiology and prognosis of breast cancer in young women. J. Thorac. Dis.5(Suppl. 1), S2–S8 (2013).
   PubMedGoogle Scholar
• Maishman T , CutressRI, HernandezAet al. Local recurrence and breast oncological surgery in young women with breast cancer: the POSH observational cohort study. Ann. Surg.266(1), 165–172 (2017).
   PubMed Web of Science ®Google Scholar
• Anders CK , FanC, ParkerJSet al. Breast carcinomas arising at a young age: unique biology or a surrogate for aggressive intrinsic subtypes? J. Clin. Oncol. 29(1), e18–e20 (2010).
   PubMed Web of Science ®Google Scholar
• Collins LC , MarottiJD, GelberSet al. Pathologic features and molecular phenotype by patient age in a large cohort of young women with breast cancer. Breast Cancer Res. Treat.131(3), 1061–1066 (2012).
   PubMed Web of Science ®Google Scholar
• Gnerlich JL , DeshpandeAD, JeffeDB, SweetA, WhiteN, MargenthalarJA. Elevated breast cancer mortality in women younger than age 40 years compared with older women is attributed to poorer survival in early-stage disease. J. Am. Coll. Surg.208(3), 341–347 (2008).
   Web of Science ®Google Scholar
• Fredholm H , EakerS, FrisellJ, HolmbergL, FredrikssonI, LindmanH. Breast cancer in young women: poor survival despite intensive treatment. PLOS ONE4(11), e7695 (2009).
   PubMed Web of Science ®Google Scholar
• Laurberg T , LyngholmCD, ChristiansenP, AlserJ, OvergrrrdJ. Long-term age-dependent failure pattern after breast-conserving therapy or mastectomy among Danish lymph-node-negative breast cancer patients. Radiother. Oncol.120(1), 98–106 (2016).
   PubMed Web of Science ®Google Scholar
• Hartmann-Johnsen OJ , KåresenR, SchlichtingE, NygårdJF. Survival is better after breast conserving therapy than mastectomy for early stage breast cancer: a registry-based follow-up study of Norwegian women primary operated between 1998 and 2008. Ann. Surg. Oncol.22(12), 3836–3845 (2015).
   PubMed Web of Science ®Google Scholar
• Marissa CM , LindaM, GeertruidaHBet al. 10 year survival after breast-conserving surgery plus radiotherapy compared with mastectomy in early breast cancer in the Netherlands: a population-based study. Lancet Oncol.17(8), 1158–1170 (2016).
   PubMed Web of Science ®Google Scholar
• Amin MB , GreeneFL, EdgeSBet al. The Eighth Edition AJCC Cancer Staging Manual: continuing to build a bridge from a population-based to a more ‘personalized’ approach to cancer staging. CA Cancer J. Clin.67(2), 93–99 (2017).
   PubMed Web of Science ®Google Scholar
• Guo R , SiJ, XueJet al. Changing patterns and survival improvements of young breast cancer in China and SEER database, 1999–2017. Chin. J. Cancer Res.31(4), 653–662 (2019).
   PubMed Web of Science ®Google Scholar
• Cao M , LiH, SunD, ChenW. Cancer burden of major cancers in China: a need for sustainable actions. Cancer Commun.40(5), 205–210 (2020).
   PubMed Web of Science ®Google Scholar
• Fan L , Strasser-WeipplK, LiJ-Jet al. Breast cancer in China. Lancet Oncol.15(7), e279–e289 (2014).
   PubMed Web of Science ®Google Scholar
• Hammond ME , HayesDF, DowsettMet al. American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. J. Clin. Oncol.28(16), 2784–95 (2010).
   PubMed Web of Science ®Google Scholar
• Lian W , FuF, LinYet al. The impact of young age for prognosis by subtype in women with early breast cancer. Sci. Rep.7(1), 11625 (2017).
   PubMedGoogle Scholar
• Chen H-L , ZhouM-Q, TianW, MengK, HeH. Effect of age on breast cancer patient prognoses: a population-based study using the SEER 18 database. PLOS ONE11(10), e0165409 (2016).
   PubMed Web of Science ®Google Scholar
• Bharat A , AftRL, GaoF, MargenthalerJA. Patient and tumor characteristics associated with increased mortality in young women (< or =40 years) with breast cancer. J. Surg. Oncol.100(3), 248–251 (2009).
   PubMed Web of Science ®Google Scholar
• Tao L , SchwabRB, SanMiguel Yet al. Breast cancer mortality in older and younger patients in California. Cancer Epidemiol. Biomarkers Prev. 28(2), 303–310 (2019).
   PubMed Web of Science ®Google Scholar
• Kroman N , HoltvegH, WohlfahrtJet al. Effect of breast-conserving therapy versus radical mastectomy on prognosis for young women with breast carcinoma. Cancer100(4), 688–693 (2004).
   PubMed Web of Science ®Google Scholar
• Blichert-Toft M , NielsenM, DüringMet al. Long-term results of breast conserving surgery vs. mastectomy for early stage invasive breast cancer: 20-year follow-up of the Danish randomized DBCG-82TM protocol. Acta Oncol.47(4), 672–681 (2008).
   PubMed Web of Science ®Google Scholar
• Litière S , WerutskyG, FentimanISet al. Breast conserving therapy versus mastectomy for stage I–II breast cancer: 20 year follow-up of the EORTC 10.01 phase 3 randomised trial. Lancet Oncol.13(4), 412–419 (2012).
   PubMed Web of Science ®Google Scholar
• van der Sangen MJC , vande Wiel FMM, PoortmansPMPet al. Are breast conservation and mastectomy equally effective in the treatment of young women with early breast cancer? Long-term results of a population-based cohort of 1451 patients aged ≤40 years. Breast Cancer Res. Treat.127(1), 207–215 (2011).
   PubMed Web of Science ®Google Scholar
• Cao JQ , TruongPT, OlivottoIAet al. Should women younger than 40 years of age with invasive breast cancer have a mastectomy? 15-year outcomes in a population-based cohort. Int. J. Radiat. Oncol. Biol. Phys.90(3), 509–517 (2014).
   PubMed Web of Science ®Google Scholar
• Fisher B , BauerM, MargoleseRet al. Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer. N. Engl. J. Med.312(11), 665–673 (1985).
   PubMed Web of Science ®Google Scholar
• NCCN Clinical Practice Guidelines in Oncology: Breast Cancer V.1.2012. Jenkintown: The National Comprehensive Cancer Network. (2012). Available online: www.nccn.org
   Google Scholar
• Vila J , GandiniS, GentiliniO. Overall survival according to type of surgery in young (≤40 years) early breast cancer patients: a systematic meta-analysis comparing breast-conserving surgery versus mastectomy. Breast24(3), 175–181 (2015).
   PubMed Web of Science ®Google Scholar
• Fredholm H , MagnussonK, LindströmLSet al. Long-term outcome in young women with breast cancer: a population-based study. Breast Cancer Res. Treat.160(1), 131–143 (2016).
   PubMed Web of Science ®Google Scholar
• Tang L-C , JinX, YangH-Yet al. Luminal B subtype: a key factor for the worse prognosis of young breast cancer patients in China. BMC Cancer15, 201–210 (2015).
   PubMed Web of Science ®Google Scholar
• Fan C , OhDS, WesselsLet al. Concordance among gene-expression-based predictors for breast cancer. N. Engl. J. Med.355(6), 560–569 (2006).
   PubMed Web of Science ®Google Scholar
• Albain KS , BarlowWE, ShakSet al. Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial. Lancet Oncol.11(1), 55–65 (2010).
   PubMed Web of Science ®Google Scholar
• Gieni M , AvramR, DicksonLet al. Local breast cancer recurrence after mastectomy and immediate breast reconstruction for invasive cancer: a meta-analysis. Breast21(3), 230–236 (2011).
   Web of Science ®Google Scholar
• Jagsi R , RaadRA, GoldbergSet al. Locoregional recurrence rates and prognostic factors for failure in node-negative patients treated with mastectomy: implications for postmastectomy radiation. Int. J. Radiat. Oncol. Biol. Phys.62(4), 1035–1039 (2004).
   Web of Science ®Google Scholar
• Wang X , ZhangL, ZhangXet al. Impact of clinical–pathological factors on locoregional recurrence in mastectomy patients with T1–2N1 breast cancer: who can omit adjuvant radiotherapy? Breast Cancer Res. Treat. 190(2), 277–286 (2021).
   PubMed Web of Science ®Google Scholar
• Arriagada R , LêMG, GuinebretièreJ-M, DunantA, RochardF, TurszT. Late local recurrences in a randomised trial comparing conservative treatment with total mastectomy in early breast cancer patients. Ann. Oncol.14(11), 1617–1622 (2003).
   PubMed Web of Science ®Google Scholar
• EBCTCG (Early Breast Cancer Trialists’ Collaborative Group) , McGaleP, TaylorCet al.Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials. Lancet383(9935), 2127–2135 (2014).
   PubMed Web of Science ®Google Scholar
• Early Breast Cancer Trialists’ Collaborative Group (EBCTCG) , DaviesC, GodwinJet al.Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials. Lancet378(9793), 771–784 (2011).
   PubMed Web of Science ®Google Scholar
• Francis PA , PaganiO, FlemingGFet al. Tailoring adjuvant endocrine therapy for premenopausal breast cancer. N. Engl. J. Med.379(2), 122–137 (2018).
   PubMed Web of Science ®Google Scholar
• Trovo M , DurofilE, PoleselJet al. Locoregional failure in early-stage breast cancer patients treated with radical mastectomy and adjuvant systemic therapy: which patients benefit from postmastectomy irradiation? Int. J. Radiat. Oncol. Biol. Phys. 83(2), e153–157 (2012).
   PubMed Web of Science ®Google Scholar
• Meattini I , LambertiniM, DesideriI, DeCaluwé A, Kaidar-PersonO, LiviL. Radiation therapy for young women with early breast cancer: current state of the art. Crit. Rev. Oncol. Hematol.137, 143–153 (2019).
   PubMed Web of Science ®Google Scholar
• Wallgren A , BonettiM, GelberRDet al. Risk factors for locoregional recurrence among breast cancer patients: results from International Breast Cancer Study Group trials I through VII. J. Clin. Oncol.21(7), 1205–1213 (2003).
   PubMed Web of Science ®Google Scholar
• Yildirim E , BerberogluU. Can a subgroup of node-negative breast carcinoma patients with T1–2 tumor who may benefit from postmastectomy radiotherapy be identified?Int. J. Radiat. Oncol. Biol. Phys.68(4), 1024–1029 (2007).
   PubMed Web of Science ®Google Scholar
• Copson ER , MaishmanTC, TapperWJet al. Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study. Lancet Oncol.19(2), 169–180 (2018).
   PubMed Web of Science ®Google Scholar
• Anders CK , HsuDS, BroadwaterGet al. Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression. J. Clin. Oncol.26(20), 3324–3330 (2007).
   Web of Science ®Google Scholar
• Magnoni F , CorsoG. Progress in breast cancer surgical management. Eur. J. Cancer Prev.31(6), 551–553 (2022).
   PubMed Web of Science ®Google Scholar
• Sun J , MengH, YaoLet al. Germline mutations in cancer susceptibility genes in a large series of unselected breast cancer patients. Clin. Cancer Res.23(20), 6113–6119 (2017).
   PubMed Web of Science ®Google Scholar
• Yao L , SunJ, ZhangJet al. Breast cancer risk in Chinese women with BRCA1 or BRCA2 mutations. Breast Cancer Res. Treat.156(3), 441–445 (2016).
   PubMed Web of Science ®Google Scholar
• Corso G , MagnoniF. Hereditary breast cancer: translation into clinical practice of recent American Society of Clinical Oncology, American Society of Radiation Oncology, and Society of Surgical Oncology recommendations. Eur. J. Cancer Prev.30(4), 311–314 (2021).
   PubMed Web of Science ®Google Scholar