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Review

Fetal Cell Microchimerism in Cancer: A Meaningful Event?

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Pages 1441-1448 | Published online: 10 Nov 2009

Bibliography

  • Reed W , HannisdalE, SkovlundE, ThoresenS, LillengP, NeslandJM: Pregnancy and breast cancer: a population-based study.Virchows Arch.443(1), 44–50 (2003).
  • Slingluff CL Jr , ReintgenDS, VollmerRT, SeiglerHF: Malignant melanoma arising during pregnancy. A study of 100 patients.Ann. Surg.211(5), 552–557 (1990).
  • Khosrotehrani K , BianchiDW: Multi-lineage potential of fetal cells in maternal tissue: a legacy in reverse.J. Cell Sci.118(Pt 8), 1559–1563 (2005).
  • Nguyen Huu S , DubernardG, AractingiS, KhosrotehraniK: Feto–maternal cell trafficking: a transfer of pregnancy associated progenitor cells.Stem Cell Rev.2(2), 111–116 (2006).
  • Ariga H , OhtoH, BuschMPet al.: Kinetics of fetal cellular and cell-free DNA in the maternal circulation during and after pregnancy: implications for noninvasive prenatal diagnosis.Transfusion41(12), 1524–1530 (2001).
  • Krabchi K , Gros-LouisF, YanJet al.: Quantification of all fetal nucleated cells in maternal blood between the 18th and 22nd weeks of pregnancy using molecular cytogenetic techniques.Clin. Genet.60(2), 145–150 (2001).
  • Holzgreve W , GhezziF, Di NaroE, GanshirtD, MaymonE, HahnS: Disturbed feto–maternal cell traffic in preeclampsia.Obstet. Gynecol.91(5 Pt 1), 669–672 (1998).
  • Bianchi DW , WilliamsJM, SullivanLM, HansonFW, KlingerKW, ShuberAP: PCR quantitation of fetal cells in maternal blood in normal and aneuploid pregnancies.Am. J. Hum. Genet.61(4), 822–829 (1997).
  • Bianchi DW , FarinaA, WeberWet al.: Significant fetal-maternal hemorrhage after termination of pregnancy: implications for development of fetal cell microchimerism.Am. J. Obstet. Gynecol.184(4), 703–706 (2001).
  • Khosrotehrani K , JohnsonKL, LauJ, DupuyA, ChaDH, BianchiDW: The influence of fetal loss on the presence of fetal cell microchimerism: a systematic review.Arthritis Rheum.48(11), 3237–3241 (2003).
  • Bonney EA , MatzingerP: The maternal immune system’s interaction with circulating fetal cells.J. Immunol.158(1), 40–47 (1997).
  • Khosrotehrani K , JohnsonKL, GueganS, StrohH, BianchiDW: Natural history of fetal cell microchimerism during and following murine pregnancy.J. Reprod. Immunol.66(1), 1–12 (2005).
  • Lambert NC , EvansPC, HashizumiTLet al.: Cutting edge: persistent fetal microchimerism in T lymphocytes is associated with HLA-DQA1*0501: implications in autoimmunity.J. Immunol.164(11), 5545–5548 (2000).
  • Artlett CM , O’HanlonTP, LopezAM, SongYW, MillerFW, RiderLG: HLA-DQA1 is not an apparent risk factor for microchimerism in patients with various autoimmune diseases and in healthy individuals.Arthritis Rheum.48(9), 2567–2572 (2003).
  • Bianchi DW : Fetal cells in the mother: from genetic diagnosis to diseases associated with fetal cell microchimerism.Eur. J. Obstet. Gynecol. Reprod. Biol.92(1), 103–108 (2000).
  • O’Donoghue K , ChoolaniM, ChanJet al.: Identification of fetal mesenchymal stem cells in maternal blood: implications for noninvasive prenatal diagnosis.Mol. Hum. Reprod.9(8), 497–502 (2003).
  • O’Donoghue K , ChanJ, De LaFJet al.: Microchimerism in female bone marrow and bone decades after fetal mesenchymal stem-cell trafficking in pregnancy.Lancet364(9429), 179–182 (2004).
  • Bianchi DW , ZickwolfGK, WeilGJ, SylvesterS, DeMariaMA: Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum.Proc. Natl Acad. Sci. USA93(2), 705–708 (1996).
  • Lambert NC , LoYM, EricksonTDet al.: Male microchimerism in healthy women and women with scleroderma: cells or circulating DNA? A quantitative answer.Blood100(8), 2845–2851 (2002).
  • Artlett CM , CoxLA, RamosRCet al.: Increased microchimeric CD4+ T lymphocytes in peripheral blood from women with systemic sclerosis.Clin. Immunol.103(3 Pt 1), 303–308 (2002).
  • Nelson JL : Maternal-fetal immunology and autoimmune disease: is some autoimmune disease auto-alloimmune or allo-autoimmune?Arthritis Rheum.39(2), 191–194 (1996).
  • Nelson JL , FurstDE, MaloneySet al.: Microchimerism and HLA-compatible relationships of pregnancy in scleroderma.Lancet351(9102), 559–562 (1998).
  • Artlett CM , SmithJB, JimenezSA: Identification of fetal DNA and cells in skin lesions from women with systemic sclerosis.N. Engl. J. Med.338(17), 1186–1191 (1998).
  • Gannage M , AmouraZ, LantzO, PietteJC, Caillat-ZucmanS: Feto–maternal microchimerism in connective tissue diseases.Eur. J. Immunol.32(12), 3405–3413 (2002).
  • Scaletti C , VultaggioA, BonifacioSet al.: Th2-oriented profile of male offspring T cells present in women with systemic sclerosis and reactive with maternal major histocompatibility complex antigens.Arthritis Rheum.46(2), 445–450 (2002).
  • Khosrotehrani K , BianchiDW: Fetal cell microchimerism: helpful or harmful to the parous woman?Curr. Opin. Obstet. Gynecol.15(2), 195–199 (2003).
  • Khosrotehrani K , LeducM, BachyVet al.: Pregnancy allows the transfer and differentiation of fetal lymphoid progenitors into functional T and B cells in mothers.J. Immunol.180(2), 889–897 (2008).
  • Mold JE , MichaelssonJ, BurtTDet al.: Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero.Science.322(5907), 1562–1565 (2008).
  • Matsuoka K , IchinoheT, HashimotoD, AsakuraS, TanimotoM, TeshimaT: Fetal tolerance to maternal antigens improves the outcome of allogeneic bone marrow transplantation by a CD4+ CD25+ T-cell-dependent mechanism.Blood.107(1), 404–409 (2006).
  • Burlingham WJ , GrailerAP, HeiseyDMet al.: The effect of tolerance to noninherited maternal HLA antigens on the survival of renal transplants from sibling donors.N. Engl. J. Med.339(23), 1657–1664 (1998).
  • van Rood JJ , LoberizaFRJr, ZhangMJet al.: Effect of tolerance to noninherited maternal antigens on the occurrence of graft-versus-host disease after bone marrow transplantation from a parent or an HLA-haploidentical sibling.Blood.99(5), 1572–1577 (2002).
  • Molitor-Dart ML , AndrassyJ, KwunJet al.: Developmental exposure to noninherited maternal antigens induces CD4+ T regulatory cells: relevance to mechanism of heart allograft tolerance.J. Immunol.179(10), 6749–6761 (2007).
  • Burlingham WJ : A lesson in tolerance – maternal instruction to fetal cells.N. Engl. J. Med.360(13), 1355–1357 (2009).
  • Khosrotehrani K , JohnsonKL, ChaDH, SalomonRN, BianchiDW: Transfer of fetal cells with multilineage potential to maternal tissue.JAMA292(1), 75–80 (2004).
  • Khosrotehrani K , ReyesRR, JohnsonKLet al.: Fetal cells participate over time in the response to specific types of murine maternal hepatic injury.Hum. Reprod.22(3), 654–661 (2007).
  • Wang Y , IwataniH, ItoTet al.: Fetal cells in mother rats contribute to the remodeling of liver and kidney after injury.Biochem. Biophys. Res. Commun.325(3), 961–967 (2004).
  • Tan XW , LiaoH, SunL, OkabeM, XiaoZC, DaweGS: Fetal microchimerism in the maternal mouse brain: a novel population of fetal progenitor or stem cells able to cross the blood-brain barrier?Stem Cells23(10), 1443–1452 (2005).
  • Nguyen Huu S , OsterM, UzanS, ChareyreF, AractingiS, KhosrotehraniK: Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells.Proc. Natl Acad. Sci. USA104(6), 1871–1876 (2007).
  • Rosen JM , JordanCT: The increasing complexity of the cancer stem cell paradigm.Science324(5935), 1670–1673 (2009).
  • Aractingi S , KanitakisJ, EuvrardSet al.: Skin carcinoma arising from donor cells in a kidney transplant recipient.Cancer Res.65(5), 1755–1760 (2005).
  • Barozzi P , LuppiM, FacchettiFet al.: Post-transplant Kaposi sarcoma originates from the seeding of donor-derived progenitors.Nat. Med.9(5), 554–561 (2003).
  • Gadi VK , NelsonJL: Fetal microchimerism in women with breast cancer.Cancer Res.67(19), 9035–9038 (2007).
  • Gadi VK , MaloneKE, GuthrieKA, PorterPL, NelsonJL: Case–control study of fetal microchimerism and breast cancer.PLoS ONE3(3), E1706 (2008).
  • Gilmore GL , HaqB, ShadduckRK, JasthySL, ListerJ: Fetal–maternal microchimerism in normal parous females and parous female cancer patients.Exp. Hematol.36(9), 1073–1077 (2008).
  • Lambert NC , EricksonTD, YanZet al.: Quantification of maternal microchimerism by HLA-specific real-time polymerase chain reaction: studies of healthy women and women with scleroderma.Arthritis Rheum.50(3), 906–914 (2004).
  • Evans PC , LambertN, MaloneyS, FurstDE, MooreJM, NelsonJL: Long-term fetal microchimerism in peripheral blood mononuclear cell subsets in healthy women and women with scleroderma.Blood93(6), 2033–2037 (1999).
  • Darrasse-Jeze G , BergotAS, DurgeauAet al.: Tumor emergence is sensed by self-specific CD44hi memory Tregs that create a dominant tolerogenic environment for tumors in mice.J. Clin. Invest.119(9), 2648–2662 (2009).
  • Pack GT , ScharnagelIM: The prognosis for malignant melanoma in the pregnant woman.Cancer4(2), 324–334 (1951).
  • Houghton AN , FlanneryJ, ViolaMV: Malignant melanoma of the skin occurring during pregnancy.Cancer48(2), 407–410 (1981).
  • Reintgen DS , McCartyKSJr, VollmerR, CoxE, SeiglerHF: Malignant melanoma and pregnancy.Cancer55(6), 1340–1344 (1985).
  • O’Meara AT , CressR, XingG, DanielsenB, SmithLH: Malignant melanoma in pregnancy. A population-based evaluation.Cancer.103(6), 1217–1226 (2005).
  • MacKie RM , BufalinoR, MorabitoA, SutherlandC, CascinelliN: Lack of effect of pregnancy on outcome of melanoma. For the World Health Organisation melanoma programme.Lancet337(8742), 653–655 (1991).
  • Travers RL , SoberAJ, BerwickM, MihmMCJr, BarnhillRL, DuncanLM: Increased thickness of pregnancy-associated melanoma.Br. J. Dermatol.132(6), 876–883 (1995).
  • Albrektsen G , HeuchI, KvaleG: The short-term and long-term effect of a pregnancy on breast cancer risk: a prospective study of 802,457 parous Norwegian women.Br. J. Cancer.72(2), 480–484 (1995).
  • Lambe M , HsiehC, TrichopoulosD, EkbomA, PaviaM, AdamiHO: Transient increase in the risk of breast cancer after giving birth.N. Engl. J. Med.331(1), 5–9 (1994).
  • Cha D , KhosrotehraniK, KimY, StrohH, BianchiDW, JohnsonKL: Cervical cancer and microchimerism.Obstet. Gynecol.102(4), 774–781 (2003).
  • O’Donoghue K , SultanHA, Al AllafFA, AndersonJR, Wyatt-AshmeadJ, FiskNM: Microchimeric fetal cells cluster at sites of tissue injury in lung decades after pregnancy.Reprod. Biomed. Online.16(3), 382–390 (2008).
  • Cirello V , RecalcatiMP, MuzzaMet al.: Fetal cell microchimerism in papillary thyroid cancer: a possible role in tumor damage and tissue repair.Cancer Res.68(20), 8482–8488 (2008).
  • Dubernard G , OsterM, ChareyreFet al.: Increased fetal cell microchimerism in high grade breast carcinomas occurring during pregnancy.Int. J. Cancer.124(5), 1054–1059 (2009).
  • Nguyen Huu S , KhosrotehraniK, OsterM, MogueletP, EspieMJ, AractingiS: Early phase of maternal skin carcinogenesis recruits long-term engrafted fetal cells.Int. J. Cancer.123(11), 2512–2517 (2008).
  • Dubernard G , AractingiS, OsterMet al.: Breast cancer stroma frequently recruits fetal derived cells during pregnancy.Breast Cancer Res.10(1), R14 (2008).
  • Nguyen Huu S , OsterM, AvrilMFet al.: Fetal microchimeric cells participate in tumor angiogenesis in melanomas occurring during pregnancy.Am. J. Pathol.174(2), 630–637 (2009).
  • Sawicki JA : Fetal microchimerism and cancer.Cancer Res.68(23), 9567–9569 (2008).
  • Galiano RD , TepperOM, PeloCRet al.: Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis and by mobilizing and recruiting bone marrow-derived cells.Am. J. Pathol.164(6), 1935–1947 (2004).
  • Studeny M , MariniFC, ChamplinRE, ZompettaC, FidlerIJ, AndreeffM: Bone marrow-derived mesenchymal stem cells as vehicles for interferon-β delivery into tumors.Cancer Res.62(13), 3603–3608 (2002).
  • Karnoub AE , DashAB, VoAPet al.: Mesenchymal stem cells within tumor stroma promote breast cancer metastasis.Nature.449(7162), 557–563 (2007).
  • Dadras SS , Lange-AsschenfeldtB, VelascoPet al.: Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes.Mod. Pathol.18(9), 1232–1242 (2005).
  • Dadras SS , PaulT, BertonciniJet al.: Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival.Am. J. Pathol.162(6), 1951–1960 (2003).

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