Advanced search
Publication Cover
Future Oncology Volume 7, 2011 - Issue 10
Submit an article Journal homepage
300
Views
0
CrossRef citations to date
0
Altmetric
Editorial

Is There a Potential Use for C-Reactive Protein as a Diagnostic and Prognostic Marker for Colorectal Cancer?

Adetunji T Toriola1 Division of Preventive Oncology, National Center for Tumor Diseases & German Cancer Research Center, Im Neuenheimer Feld 460, 69120, Heidelberg, GermanyView further author information
&
Cornelia M Ulrich1 Division of Preventive Oncology, National Center for Tumor Diseases & German Cancer Research Center, Im Neuenheimer Feld 460, 69120, Heidelberg, Germany;2 Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. [email protected]Correspondence[email protected]
View further author information
Pages 1125-1128 | Published online: 12 Oct 2011

Bibliography

  • Pepys MB , HirschfieldGM. C-reactive protein, a critical update.J. Clin. Invest.111, 1805–1812 (2003).
  • Tillett WS , FrancisT. Serological reactions in pneumonia with a non-protein somatic fraction of pneumococcus.J. Exp. Med.52, 561–571 (1930).
  • Pepys MB . CRP or not CRP? That is the question.Arterioscler. Thromb. Vasc. Biol.25, 1091–1094 (2005).
  • Gabay C , KushnerI. Acute-phase proteins and other systemic responses to inflammation.N. Engl. J. Med.340, 448–454 (1999).
  • Pepys MB , BaltzML. Acute phase proteins with special reference to C-reactive protein and related proteins (pentaxins) and serum amyloid A protein.Adv. Immunol.34, 141–212 (1983).
  • Hurlimann J , ThorbeckeGJ, HochwaldGM. The liver as the site of C-reactive protein formation.J. Exp. Med.123, 365–378 (1966).
  • Danesh J , MuirJ, WongYK, WardM, GallimoreJR, PepysMB. Risk factors for coronary heart disease and acute-phase proteins. A population-based study.Eur. Heart J.20, 954–959 (1999).
  • Yudkin JS , StehouwerCD, EmeisJJ, CoppackSW. C-reactive protein in healthy subjects, associations with obesity, insulin resistance, and endothelial dysfunction, a potential role for cytokines originating from adipose tissue?Arterioscler. Thromb. Vasc. Biol.19, 972–978 (1999).
  • Ockene IS , MatthewsCE, RifaiN, RidkerPM, ReedG, StanekE. Variability and classification accuracy of serial high-sensitivity C-reactive protein measurements in healthy adults.Clin. Chem.47, 444–450 (2001).
  • Vigushin DM , PepysMB, HawkinsPN. Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease.J. Clin. Invest.91, 1351–1357 (1993).
  • Kaptoge S , Di AngelantonioE, LoweGet al.; Emerging Risk Factors Collaboration. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality, an individual participant meta-analysis.Lancet375, 132–140 (2010).
  • Ulrich CM , BiglerJ, PotterJD. Non-steroidal anti-inflammatory drugs for cancer prevention, promise, perils, and pharmacogenetics.Nat. Rev. Cancer6, 130–140 (2006).
  • Ullman TA , ItzkowitzSH. Intestinal inflammation and cancer.Gastroenterology140, 1807–1816 (2011).
  • Rothwell PM , WilsonM, ElwinCEet al. Long-term effect of aspirin on colorectal cancer incidence and mortality, 20-year follow-up of five randomised trials. Lancet 376, 1741–1750 (2010).
  • Flossmann E , RothwellPM. Effect of aspirin on long-term risk of colorectal cancer, consistent evidence from randomised and observational studies.Lancet369, 1603–1613 (2007).
  • Vane JR . Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.Nat. New. Biol.231, 232–235 (1971).
  • Dubois RN . Nonsteroidal antiinflammatory drugs, cyclooxygenase-2, and colorectal cancer prevention.Curr. Opin Gastroenterol.17, 65–71 (2001).
  • Gunter MJ , CrossAJ, HuangWYet al. A prospective evaluation of C-reactive protein levels and colorectal adenoma development. Cancer Epidemiol. Biomarkers Prev. 20, 537–544 (2011).
  • Tsilidis KK , ErlingerTP, RifaiNet al. C-reactive protein and colorectal adenoma in the CLUE II cohort. Cancer Causes Control 19, 559–567 (2008).
  • Erlinger TP , PlatzEA, RifaiN, HelzlsouerKJ. C-reactive protein and the risk of incident colorectal cancer.JAMA291, 585–590 (2004).
  • Zhang SM , BuringJE, LeeIM, CookNR, RidkerPM. C-reactive protein levels are not associated with increased risk for colorectal cancer in women.Ann. Intern. Med.142, 425–432 (2005).
  • Ito Y , SuzukiK, TamakoshiKet al. Colorectal cancer and serum C-reactive protein levels: a case-control study nested in the JACC Study. J. Epidemiol. 15(Suppl. 2), S185–S189 (2005).
  • Il’Yasova D , ColbertLH, HarrisTBet al. Circulating levels of inflammatory markers and cancer risk in the health aging and body composition cohort. Cancer Epidemiol. Biomarkers Prev. 14, 2413–2418 (2005).
  • Gunter MJ , Stolzenberg-SolomonR, CrossAJet al. A prospective study of serum C-reactive protein and colorectal cancer risk in men. Cancer Res. 66, 2483–2487 (2006).
  • Otani T , IwasakiM, SasazukiSet al. Plasma C-reactive protein and risk of colorectal cancer in a nested case-control study: Japan Public Health Center-based prospective study. Cancer Epidemiol. Biomarkers Prev. 15, 690–695 (2006).
  • Trichopoulos D , PsaltopoulouT, OrfanosP, TrichopoulouA, BoffettaP. Plasma C-reactive protein and risk of cancer: a prospective study from Greece.Cancer Epidemiol. Biomarkers Prev.15, 381–384 (2006).
  • Siemes C , VisserLE, CoeberghJWet al. C-reactive protein levels, variation in the C-reactive protein gene, and cancer risk: the Rotterdam Study. J. Clin. Oncol. 24, 5216–5222 (2006).
  • Chiu HM , LinJT, ChenTHet al. Elevation of C-reactive protein level is associated with synchronous and advanced colorectal neoplasm in men. Am. J. Gastroenterol. 103, 2317–2325 (2008).
  • Heikkila K , HarrisR, LoweGet al. Associations of circulating C-reactive protein and interleukin-6 with cancer risk, findings from two prospective cohorts and a meta-analysis. Cancer Causes Control 20, 15–26 (2009).
  • Allin KH , BojesenSE, NordestgaardBG. Baseline C-reactive protein is associated with incident cancer and survival in patients with cancer.J. Clin. Oncol.27, 2217–2224 (2009).
  • Aleksandrova K , JenabM, BoeingHet al. Circulating C-reactive protein concentrations and risks of colon and rectal cancer: a nested case-control study within the European Prospective Investigation into Cancer and Nutrition. Am. J. Epidemiol. 172, 407–418 (2010).
  • Chan AT , OginoS, GiovannucciEL, FuchsCS. Inflammatory markers are associated with risk of colorectal cancer and chemopreventive response to anti-inflammatory drugs.Gastroenterology140, 799–808, quiz e711 (2011).
  • Prizment AE , AndersonKE, VisvanathanK, FolsomAR. Association of inflammatory markers with colorectal cancer incidence in the atherosclerosis risk in communities study.Cancer Epidemiol. Biomarkers Prev.20, 297–307 (2011).
  • Van Hemelrijck M , HolmbergL, GarmoHet al. Association between levels of C-reactive protein and leukocytes and cancer: three repeated measurements in the Swedish AMORIS study. Cancer Epidemiol. Biomarkers Prev. 20, 428–437 (2011).
  • Tsilidis KK , BranchiniC, GuallarE, HelzlsouerKJ, ErlingerTP, PlatzEA. C-reactive protein and colorectal cancer risk: a systematic review of prospective studies.Int. J. Cancer123, 1133–1140 (2008).
  • Helzlsouer KJ , ErlingerTP, PlatzEA. C-reactive protein levels and subsequent cancer outcomes, results from a prospective cohort study.Eur. J. Cancer42, 704–707 (2006).
  • Johnson JR , LaceyJV, Jr., LazovichDet al. Menopausal hormone therapy and risk of colorectal cancer. Cancer Epidemiol. Biomarkers Prev. 18, 196–203 (2009).
  • Hage FG , SzalaiAJ. C-reactive protein gene polymorphisms, C-reactive protein blood levels, and cardiovascular disease risk.J. Am. Coll. Cardiol.50, 1115–1122 (2007).
  • Slattery ML , CurtinK, PooleEMet al. Genetic variation in C-reactive protein in relation to colon and rectal cancer risk and survival. Int. J. Cancer 128, 2726–2734 (2011).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.