43
Views
0
CrossRef citations to date
0
Altmetric
Editorial

Vaccine Therapy + Dasatinib for the Treatment of Patients with Stage IIIB–IV Melanoma

, &
Pages 251-254 | Received 15 May 2016, Accepted 03 Jun 2016, Published online: 29 Nov 2016

References

  • Cancer Facts and Figures 2016. American Cancer Society, Atlanta, GA, USA (2016). www.cancer.org/acs/groups/content/@research/documents/document/acspc-047079.pdf
  • Balch CM , GershenwaldJE, SoongSJet al. Final version of 2009 AJCC melanoma staging and classification. J. Clin. Oncol.27 (36), 6199 – 6206 (2007).
  • Harries M , MalvehyJ, LebbeCet al. Treatment patterns of advanced malignant melanoma (stage III–IV) – a review of current standards in Europe. Eur. J. Cancer60, 179 – 189 (2016).
  • Larkin J , Chiarion-SileniV, GonzalezRet al. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N. Engl. J. Med.373 (1), 23 – 34 (2015).
  • Ascierto ML , MeleroI, AsciertoPA. Melanoma: from incurable beast to a curable bet. The success of immunotherapy. Front. Oncol.5, 152 (2015).
  • Zarour HM . Reversing T-cell dysfunction and exhaustion in cancer. Clin. Cancer Res.22 (8), 1856 – 1864 (2016).
  • Melero I , GaudernackG, GerritsenWet al. Therapeutic vaccines for cancer: an overview of clinical trials. Nat. Rev. Clin. Oncol.11 (9), 509 – 524 (2014).
  • Chi M , DudekAZ. Vaccine therapy for metastatic melanoma: systematic review and meta-analysis of clinical trials. Melanoma Res.21 (3), 165 – 174 (2011).
  • Salerno EP , SheaSM, OlsonWCet al. Activation, dysfunction and retention of T cells in vaccine sites after injection of incomplete Freund’s adjuvant, with or without peptide. Cancer Immunol. Immunother.62 (7), 1149 – 1159 (2013).
  • Zhang Y , ErtlHC. Starved and asphyxiated: how can CD8+ T cells within a tumor microenvironment prevent tumor progression. Front. Immunol.7, 32 (2016).
  • Ohta A . A metabolic immune checkpoint: adenosine in tumor microenvironment. Front. Immunol.7, 109 (2016).
  • Zhao X , BoseA, KomitaHet al. Vaccines targeting tumor blood vessel antigens promote CD8+ T cell-dependent tumor eradication or dormancy in HLA-A2 transgenic mice. J. Immunol.188 (4), 1782 – 1788 (2012).
  • Chi Sabins N , TaylorJL, FabianKPet al. DLK1: a novel target for immunotherapeutic remodeling of the tumor blood vasculature. Mol. Ther.21 (10), 1958 – 1968 (2013).
  • Huang Y , GoelS, DudaDG, FukumuraD, JainRK. Vascular normalization as an emerging strategy to enhance cancer immunotherapy. Cancer Res.73 (10), 2943 – 2948 (2013).
  • Kwilas AR , DonahueRN, TsangKY, HodgeJW. Immune consequences of tyrosine kinase inhibitors that synergize with cancer immunotherapy. Cancer Cell Microenviron.2 (1), e677 (2015).
  • Lowe DB , BoseA, TaylorJLet al. Dasatinib promotes the expansion of a therapeutically superior T-cell repertoire in response to dendritic cell vaccination against melanoma. Oncoimmunology3 (1), e27589 (2014).
  • Maes H , KuchnioA, PericAet al. Tumor vessel normalization by chloroquine independent of autophagy. Cancer Cell26 (2), 190 – 206 (2014).
  • BMS-354825 , Bristol-Myers Squibb Investigator Brochure, Version no. 5, Version date: 26-Jan-2006. BMS Document Control No. 930003494.
  • ClinicalTrials Database: NCT01876212 . https://clinicaltrials.gov/ct2/show/NCT01876212
  • Kluger HM , DudekAZ, McCannCet al. A phase 2 trial of dasatinib in advanced melanoma. Cancer117, 2202 – 2208 (2011).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.