Polymeric Micelles Loaded In Situ Gel with Prednisolone Acetate for Ocular Inflammation: Development and Evaluation

References

• Al Khateb K , OzhmukhametovaEK, MussinMNet al. In situ gelling systems based on pluronic F127/pluronic F68 formulations for ocular drug delivery. Int. J. Pharm.502(1–2), 70–79 (2016).
   PubMedGoogle Scholar
• Alami-Milani M , Zakeri-MilaniP, ValizadehH, SalehiR, JelvehgariM. Preparation and evaluation of PCL-PEG-PCL micelles as potential nanocarriers for ocular delivery of dexamethasone. Iranian J. Basic Med. Sci.21(2), 153–164 (2018).
   PubMed Web of Science ®Google Scholar
• Alshamsan A , AbulKalam M, VakiliMRet al. Treatment of endotoxin-induced uveitis by topical application of cyclosporine a-loaded PolyGel™ in rabbit eyes. Int. J. Pharm.569, 118573 (2019).
   PubMedGoogle Scholar
• Augusto de Castro M , HenriqueReis P, FernandesCet al. Thermoresponsive in-situ gel containing hyaluronic acid and indomethacin for the treatment of corneal chemical burn. Int. J. Pharm.631, 122468 (2023).
   PubMedGoogle Scholar
• Charbe NB , AmnerkarND, RameshBet al. Small interfering RNA for cancer treatment: overcoming hurdles in delivery. Acta Pharmaceutica Sinica. B10(11), 2075–2109 (2020).
   PubMed Web of Science ®Google Scholar
• Devi S , SainiV, KumarM, BhattS, GuptaS, DeepA. A novel approach of drug localization through development of polymeric micellar system containing azelastine HCl for ocular delivery. Pharm. Nanotechnol.7(4), 314–327 (2019).
   PubMedGoogle Scholar
• Kaur J , GulatiM, FamtaPet al. Polymeric micelles loaded with glyburide and vanillic acid: I. Formulation development, in-vitro characterization and bioavailability studies. Int. J. Pharm.624, 121987 (2022).
   PubMedGoogle Scholar
• Duan Y , CaiX, DuH, ZhaiG. Novel in situ gel systems based on P123/TPGS mixed micelles and gellan gum for ophthalmic delivery of curcumin. Colloids Surfaces B. Biointerf.128, 322–330 (2015).
   PubMed Web of Science ®Google Scholar
• Famili A , KahookMY, ParkD. A combined micelle and poly(serinol hexamethylene urea)-co-poly(N-isopropylacrylamide) reverse thermal gel as an injectable ocular drug delivery system. Macromolec. Biosci.14(12), 1719–1729 (2014).
   PubMed Web of Science ®Google Scholar
• Kaur J , GulatiM, GowthamarajanKet al. Combination therapy of vanillic acid and oxaliplatin co-loaded in polysaccharide based functionalized polymeric micelles could offer effective treatment for colon cancer: a hypothesis. Med. Hypotheses156, 110679 (2021).
   PubMed Web of Science ®Google Scholar
• Mofidfar M , AbdiB, AhadianSet al. Drug delivery to the anterior segment of the eye: a review of current and future treatment strategies. Int. J. Pharmaceut.607, 120924 (2021).
   PubMed Web of Science ®Google Scholar
• Zhao X , SeahI, XueKet al. Anti-angiogenic nanomicelles for the topical delivery of aflibercept to treat retinal neovascular disease. Adv. Mater.34, 2108360 (2022).
   PubMed Web of Science ®Google Scholar
• Kurnik I , D’AngeloN, MazzolaPet al. Polymeric micelles using cholinium-based ionic liquids for the encapsulation and drug release of hydrophobic molecules. Biomat. Sci.9(9), (2021).
   PubMedGoogle Scholar
• Desai A , ChaonB, BerkenstockM. Neurosarcoidosis and ocular inflammation: a case series and literature review. J. Neuro-Ophthalmol.41(2), e259–e266 (2020).
   Web of Science ®Google Scholar
• Xing Y , ZhuL, ZhangK, LiT, HuangS. Nanodelivery of triamcinolone acetonide with PLGA-chitosan nanoparticles for the treatment of ocular inflammation. Artif. Cell. Nanomed. Biotechnol.49(1), 308–316 (2021).
   PubMed Web of Science ®Google Scholar
• Kaur J , GulatiM, KapoorBet al. Advances in designing of polymeric micelles for biomedical application in brain related diseases. Chemico-Biol. Interact.361, 109960 (2022).
   PubMed Web of Science ®Google Scholar
• Mandal A , BishtR, RupenthalI, MitraA. Polymeric micelles for ocular drug delivery: from structural frameworks to recent preclinical studies. J. Control. Rel.248, 96–116 (2017).
   PubMed Web of Science ®Google Scholar
• Ghezzi M , PescinaS, PadulaCet al. Polymeric micelles in drug delivery: an insight of the techniques for their characterization and assessment in biorelevant conditions. J. Control. Rel.332, 312–336 (2021).
   PubMed Web of Science ®Google Scholar
• Parra A , JarakI, SantosA, VeigaF, FigueirasA. Polymeric micelles: a promising pathway for dermal drug delivery. Materials (Basel, Switzerland)14(23), (2021).
   Web of Science ®Google Scholar
• Zhang X , WeiD, XuY, ZhuQ. Hyaluronic acid in ocular drug delivery. Carbohydr. Polym.264, 118006 (2021).
   PubMed Web of Science ®Google Scholar
• Allyn MM , LuoRH, HellwarthEB, Swindle-ReillyKE. Considerations for polymers used in ocular drug delivery. Front. Med.8, 787644 (2021).
   Web of Science ®Google Scholar
• Dave RS , GoostreyTC, ZiolkowskaM, Czerny-HolowniaS, HoareT, SheardownH. Ocular drug delivery to the anterior segment using nanocarriers: a mucoadhesive/mucopenetrative perspective. J. Control. Rel.336, 71–88 (2021).
   PubMed Web of Science ®Google Scholar
• Fang G , YangX, WangQ, ZhangA, TangB. Hydrogels-based ophthalmic drug delivery systems for treatment of ocular diseases. Mater. Sci. Eng. C. Mater. Biol. Appl.127, 112212 (2021).
   PubMed Web of Science ®Google Scholar
• Dosmar E , WalshJ, DoyelMet al. Targeting ocular drug delivery: an examination of local anatomy and current approaches. Bioengineering (Basel, Switzerland)9(1), (2022).
   PubMedGoogle Scholar
• Tiwari R , SethiyaNK, GulbakeAS, MehraNK, MurtyUSN, GulbakeA. A review on albumin as a biomaterial for ocular drug delivery. Int. J. Biol. Macromol.191, 591–599 (2021).
   PubMed Web of Science ®Google Scholar
• Tundisi LL , MostaçoGB, CarricondoPC, PetriDFS. Hydroxypropyl methylcellulose: physicochemical properties and ocular drug delivery formulations. Eur. J. Pharmaceut. Sci.159, 105736 (2021).
   PubMed Web of Science ®Google Scholar
• Achouri D , AlhanoutK, PiccerelleP, AndrieuV. Recent advances in ocular drug delivery. Drug Dev. Industr. Pharm.39(11), 1599–1617 (2013).
   PubMed Web of Science ®Google Scholar
• Sipos B , Budai-SzűcsM, KókaiDet al. Erythromycin-loaded polymeric micelles: in situ gel development, in vitro and ex vivo ocular investigations. Eur. J. Pharmaceut. Biopharmaceut.180, 81–90 (2022).
   PubMed Web of Science ®Google Scholar
• Sipos B , CsókaI, AmbrusRet al. Spray-dried indomethacin-loaded polymeric micelles for the improvement of intestinal drug release and permeability. Eur. J. Pharmaceut. Sci.174, 106200 (2022).
   PubMed Web of Science ®Google Scholar
• Suksiriworapong J , RungvimolsinT, A-GomolA, JunyaprasertVB, ChantasartD. Development and characterization of lyophilized diazepam-loaded polymeric micelles. AAPS Pharm. Sci. Tech.15(1), 52–64 (2014).
   PubMed Web of Science ®Google Scholar
• Valenzuela-Oses JK , GarcíaMC, FeitosaVAet al. Development and characterization of miltefosine-loaded polymeric micelles for cancer treatment. Mater. Sci. Eng. C. Mater. Biol. Appl.81, 327–333 (2017).
   PubMed Web of Science ®Google Scholar
• Wang MY , QuY, HuDRet al. Methotrexate-loaded biodegradable polymeric micelles for lymphoma therapy. Int. J. Pharm.557, 74–85 (2019).
   PubMedGoogle Scholar
• Zhao L , ShiY, ZouS, SunM, LilL, ZhailG. Formulation and in vitro evaluation of quercetin loaded polymeric micelles composed of pluronic P123 and D-a-tocopheryl polyethylene glycol succinate. J. Biomed. Nanotechnol.7(3), 358–365 (2011).
   PubMed Web of Science ®Google Scholar
• Akhter MH , AhmadI, AlshahraniMYet al. Drug delivery challenges and current progress in nanocarrier-based ocular therapeutic system. Gels (Basel, Switzerland)8(2), (2022).
   Web of Science ®Google Scholar
• Koutsoviti M , SiamidiA, PavlouP, VlachouM. Recent advances in the excipients used for modified ocular drug delivery. Materials (Basel, Switzerland)14(15), (2021).
   PubMed Web of Science ®Google Scholar
• Gupta B , MishraV, GharatS, MominM, OmriA. Cellulosic polymers for enhancing drug bioavailability in ocular drug delivery systems. Pharmaceuticals (Basel, Switzerland)14(11), (2021).
   Google Scholar
• Berillo D , ZharkinbekovZ, KimY, RaziyevaK, TemirkhanovaK, SaparovA. Stimuli-responsive polymers for transdermal, transmucosal and ocular drug delivery. Pharmaceutics13(12), (2021).
   PubMed Web of Science ®Google Scholar
• Bhandari A . Ocular fluid mechanics and drug delivery: a review of mathematical and computational models. Pharm. Res.38(12), 2003–2033 (2021).
   PubMed Web of Science ®Google Scholar
• Bodoki AE , IacobBC, DinteE, VostinaruO, SamoilaO, BodokiE. Perspectives of molecularly imprinted polymer-based drug delivery systems in ocular therapy. Polymers13(21), (2021).
   PubMed Web of Science ®Google Scholar
• Conrady CD , YehS. A review of ocular drug delivery platforms and drugs for infectious and noninfectious uveitis: the past, present, and future. Pharmaceutics13(8), (2021).
   PubMed Web of Science ®Google Scholar
• Abd-Elsalam WH , El-ZahabySA, Al-MahallawiAM. Formulation and in vivo assessment of terconazole-loaded polymeric mixed micelles enriched with Cremophor EL as dual functioning mediator for augmenting physical stability and skin delivery. Drug Deliv.25(1), 484–492 (2018).
   PubMed Web of Science ®Google Scholar
• Abdollahi AR , FirouzianF, HaddadiR, NourianA. Indomethacin loaded dextran stearate polymeric micelles improve adjuvant-induced arthritis in rats: design and in vivo evaluation. Inflammopharmacology29(1), 107–121 (2021).
   PubMed Web of Science ®Google Scholar
• Bagheri M , FensMH, KleijnTGet al. In vitro and in vivo studies on HPMA-based polymeric micelles loaded with curcumin. Mol. Pharmaceut.18(3), 1247–1263 (2021).
   PubMed Web of Science ®Google Scholar
• Cabral H , KataokaK. Progress of drug-loaded polymeric micelles into clinical studies. J. Control. Rel.190, 465–476 (2014).
   PubMed Web of Science ®Google Scholar
• Deshmukh AS , ChauhanPN, NoolviMNet al. Polymeric micelles: basic research to clinical practice. Int. J. Pharm.532(1), 249–268 (2017).
   PubMed Web of Science ®Google Scholar
• Fan H , ZhangP, ZhouLet al. Naringin-loaded polymeric micelles as buccal tablets: formulation, characterization, in vitro release, cytotoxicity and histopathology studies. Pharmaceut. Develop. Technol.25(5), 547–555 (2020).
   PubMed Web of Science ®Google Scholar
• Ghezzi M , FerraboschiI, DelledonneAet al. Cyclosporine-loaded micelles for ocular delivery: investigating the penetration mechanisms. J. Control. Rel.349, 744–755 (2022).
   PubMed Web of Science ®Google Scholar
• Gupta A , CostaAP, XuXet al. Formulation and characterization of curcumin loaded polymeric micelles produced via continuous processing. Int. J. Pharm.583, 119340 (2020).
   PubMedGoogle Scholar
• Janas C , MostaphaouiZ, SchmiedererL, BauerJ, WackerMG. Novel polymeric micelles for drug delivery: material characterization and formulation screening. Int. J. Pharm.509(1–2), 197–207 (2016).
   PubMedGoogle Scholar
• Madan JR , DereSG, AwasthiR, DuaK. Efavirenz loaded mixed polymeric micelles: formulation, optimization, and in vitro characterization. Assay Drug Dev. Technol.19(5), 322–334 (2021).
   PubMed Web of Science ®Google Scholar
• Majumder N , DasNG, DasSK. Polymeric micelles for anticancer drug delivery. Ther. Deliv.11(10), 613–635 (2020).
   PubMed Web of Science ®Google Scholar
• Mochida Y , CabralH, KataokaK. Polymeric micelles for targeted tumor therapy of platinum anticancer drugs. Expert Opin. Drug Deliv.14(12), 1423–1438 (2017).
   PubMed Web of Science ®Google Scholar
• Nardi M , SarubbiE, SomavarapuS. Eco-friendly synthesis of PEtOz-PA: a promising polymer for the formulation of curcumin-loaded micelles. Molecules (Basel, Switzerland)27(12), (2022).
   Web of Science ®Google Scholar
• Patil PH , WankhedePR, MahajanHS, ZawarLR. Aripiprazole-loaded polymeric micelles: fabrication, optimization and evaluation using response surface method. Recent Pat. Drug Deliv. Formul.12(1), 53–64 (2018).
   PubMedGoogle Scholar
• Saxena V , HussainMD. Formulation and in vitro evaluation of 17-allyamino-17-demethoxygeldanamycin (17-AAG) loaded polymeric mixed micelles for glioblastoma multiforme. Colloid. Surf. B. Biointerf.112, 350–355 (2013).
   PubMed Web of Science ®Google Scholar
• Sipos B , CsókaI, Budai-SzűcsMet al. Development of dexamethasone-loaded mixed polymeric micelles for nasal delivery. Eur. J. Pharmaceut. Sci.166, 105960 (2021).
   PubMed Web of Science ®Google Scholar
• Srivastava S , KumarA, YadavPKet al. Formulation and performance evaluation of polymeric mixed micelles encapsulated with baicalein for breast cancer treatment. Drug Develop. Industr. Pharm.47(9), 1512–1522 (2021).
   PubMed Web of Science ®Google Scholar
• Watanabe M , KawanoK, YokoyamaM, OpanasopitP, OkanoT, MaitaniY. Preparation of camptothecin-loaded polymeric micelles and evaluation of their incorporation and circulation stability. Int. J. Pharm.308(1–2), 183–189 (2006).
   PubMedGoogle Scholar
• Wei Z , HaoJ, YuanSet al. Paclitaxel-loaded pluronic P123/F127 mixed polymeric micelles: formulation, optimization and in vitro characterization. Int. J. Pharm.376(1–2), 176–185 (2009).
   PubMed Web of Science ®Google Scholar
• Sharma A , ShambhwaniD, PandeySet al. Advances in lung cancer treatment using nanomedicines. ACS Omega8(1), 10–41 (2023).
   PubMed Web of Science ®Google Scholar
• Kaur J , MishraV, SinghSKet al. Harnessing amphiphilic polymeric micelles for diagnostic and therapeutic applications: breakthroughs and bottlenecks. J. Control. Rel.334, 64–95 (2021).
   PubMed Web of Science ®Google Scholar
• Xie YJ , WangQL, Adu-FrimpongMet al. Preparation and evaluation of isoliquiritigenin-loaded F127/P123 polymeric micelles. Drug Develop. Industr. Pharm.45(8), 1224–1232 (2019).
   PubMed Web of Science ®Google Scholar
• Zhang Y , HuangY, LiS. Polymeric micelles: nanocarriers for cancer-targeted drug delivery. AAPS PharmSciTech15(4), 862–871 (2014).
   PubMed Web of Science ®Google Scholar
• Kaur J , GulatiM, ZacconiFet al. Biomedical applications of polymeric micelles in the treatment of diabetes mellitus: current success and future approaches. Expert Opin. Drug Deliv.19(7), 771–793 (2022).
   PubMed Web of Science ®Google Scholar
• Zhou H , QiZ, XueX, WangC. Novel pH-sensitive urushiol-loaded polymeric micelles for enhanced anticancer activity. Int. J. Nanomed.15, 3851–3868 (2020).
   PubMed Web of Science ®Google Scholar
• Zhou J , JiangXH. Formulation conditions on the drug loading properties of polymeric micelles. Pak. J. Pharm. Sci.32(2), 607–615 (2019).
   PubMed Web of Science ®Google Scholar