145
Views
0
CrossRef citations to date
0
Altmetric
Research Article

New Pegylated Polyaspartamide-Based Polyplexes as Gene Delivery Vectors

, , , &
Pages 243-258 | Published online: 11 Feb 2010

Bibliography

  • Merdan T , KopecekJ, KisselT: Prospects for cationic polymers in gene and oligonucleotide therapy against cancer.Adv. Drug Del. Rev.54(5) 715–758 (2002).
  • Lechardeur D , VerkmanAS, LukacsGL: Intracellular routing of plasmid DNA during non-viral gene transfer.Adv. Drug Del. Rev.57(5) 755–767 (2005).
  • Lungwitz U , BreunigM, BlunkT, GoepferichA: Polyethylenimine-based non-viral gene delivery systems,Eur. J. Pharm. Biopharm.60(2) 247–266 (2005).
  • Gabrielson NP , PackDW: Acetylation of polyethylenimine enhances gene delivery via weakened polymer/DNA interactions.Biomacromolecules7(8) 2427–2435 (2006).
  • Gebhart CL , KabanovAV: Perspectives on polymeric gene delivery.J Bioact. Biocompat. Polym.18(2) 147–166 (2003).
  • Zeng Y , CullenBR: RNA interference in human cells is restricted to the cytoplasm.RNA8(7) 855–860 (2002).
  • Miyata K , FukushimaS, NishiyamaN, YamasakiY, KataokaK: PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection efficacy.J. Control. Release122(3) 252–260 (2007).
  • Neu M , FisherD, KisselT: Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives.J. Gene Med.7(8) 992–1009 (2005).
  • Akinc A , ThomasM, KlibanovAM, LangerR: Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis.J Gene Med.7(5) 657–663 (2005).
  • Pouton C .W, Seymour LW: Key issues in non-viral gene delivery. Adv. Drug Deliv. Rev.46(1–3) 187–203 (2001).
  • Ogris M , SteinleinP, CarottaS, BrunnerS, WagnerE: DNA/polyethylenimine transfection particles: influence of ligands, polymer size, and PEGylation on internalization and gene expression.Pharm. Sci.3(3) E21 (2001).
  • Lutz GJ , SirsiSR, WilliamsJH: PEG–PEI copolymers for oligonucleotide delivery to cells and tissues.Methods Mol. Biol.433, 141–158 (2008).
  • Mao S , NeuM, GermershausOet al.: Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/siRNA polyplexes.Bioconjug. Chem.17(5) 1209–1218 (2006).
  • Zhang XG , TengDY, WuZMet al.: PEG-grafted chitosan nanoparticles as an injectable carrier for sustained protein release.J. Mater. Sci. Mater. Med.19(12) 3525–3533 (2008).
  • Eliyahu H , ServelN, DombAJ, BarenholzY.: Lipoplex-induced hemoagglutination: potential involvement in intravenous gene delivery. Gene Ther.9(13) 850–858 (2002).
  • Clift MJD , Rothen-RutishauserB, BrownDMet al.: The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line.Toxicol. Appl. Pharmacol.232(3) 418–427 (2008).
  • Cavallaro G , ScirèS, LicciardiM, OgrisM, WagnerE, GiammonaG: Polyhydroxyethylaspartamide–spermine copolymers: efficient vectors for gene delivery.J. Control. Release131(1) 54–63 (2008).
  • Giammona G , CarlisiB, PalazzoS: Reaction of α,β-poly(hydroxyethyl)-DL -aspartamide with derivatives of carboxylic acid.J. Polym. Sci. Pol. Chem.25(10) 2813–2818 (1987).
  • Craparo EF , CavallaroG, BondìML, MandracchiaD, GiammonaG: PEGylated nanoparticles based on a polyaspartamide. Preparation, physico–chemical characterization, and intracellular uptake.Biomacromolecules7(11) 3083–3092 (2006).
  • Wolf H , RaadM, SnelCet al.: Biodegradable poly(2-dimethylamino ethylamino)phosphazene for in vivo gene delivery to tumor cells. Effect of polymer molecular weight.Pharm. Res.24(8) 1572–1580 (2007).
  • Parker AL , OupickyD, DashPR, SeymourLW: Methodologies for monitoring nanoparticle formation by self-assembly of DNA with poly(L-lysine).Anal. Biochem.302(1), 75–80 (2002).
  • Cavallaro G , LicciardiM, MandracchiaD, PitarresiG, GiammonaG: Hydrophilic and hydrophobic copolymers of a polyaspartylhydrazide bearing positive charges as vector for gene therapy.Polym. Int.57708–713 (2008).
  • Moreau E , Domurado Pascal Chapon M, Vert M, Domurado D: Biocompatibility of polycations: in vitro agglutination and lysis of red blood cells and in vivo toxicity. J. Drug Target10(2) 161–173 (2002).
  • Kichler A , LeborgneC, CoeytauxE, DanosO: Polyethylenimine-mediated gene delivery: a mechanistic study.J. Gene Med.3(2) 135–144 (2001)

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.