Impact of Hemodialysis on Exhaled Volatile Organic Compounds in End-Stage Renal Disease: A Pilot Study

• National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am. J. Kidney Dis.39(2 Suppl. 1), S1–S266 (2002).
   PubMed Web of Science ®Google Scholar
• Levey AS , AtkinsR, CoreshJet al. Chronic kidney disease as a global public health problem: approaches and initiatives a position statement from Kidney Disease Improving Global Outcomes. Kidney Int. 72(3), 247–259 (2007).
   PubMed Web of Science ®Google Scholar
• Meyer TW , HostetterTH. Uremia. N. Engl. J. Med.357(13), 1316–1325 (2007).
   PubMed Web of Science ®Google Scholar
• Collins AJ , FoleyRN, HerzogCet al. US Renal Data System 2010 Annual Data Report. Am. J. Kidney Dis. 57 (1 Suppl. 1), A1–A8, e1–e526 (2011).
   PubMed Web of Science ®Google Scholar
• Dor A , PaulyMV, EichleayMA, HeldPJ. End-stage renal disease and economic incentives: the International Study of Health Care Organization and Financing (ISHCOF). Int. J. Health Care Finance Econ.7(2–3), 73–111 (2007).
   PubMedGoogle Scholar
• Lysaght MJ . Maintenance dialysis population dynamics: current trends and long-term implications. J. Am. Soc. Nephrol.13(Suppl. 1), S37–S40 (2002).
   PubMed Web of Science ®Google Scholar
• Atkins RC . The epidemiology of chronic kidney disease. Kidney Int. Suppl.67(Suppl. 94), S14–S18 (2005).
   Google Scholar
• Grassmann A , GiobergeS, MoellerS, BrownG. End-stage renal disease: global demographics in 2005 and observed trends. Artif. Organs30(12), 895–897 (2006).
   PubMed Web of Science ®Google Scholar
• Portugal-Cohen M , OronM, Ma‘orZet al. Noninvasive skin measurements to monitor chronic renal failure pathogenesis. Biomed. Pharmacother. 65(4), 280–285 (2011).
   PubMed Web of Science ®Google Scholar
• Vanholder R , BaurmeisterU, BrunetP, CohenG, GlorieuxG, JankowskiJ. A bench to bedside view of uremic toxins. J. Am. Soc. Nephrol.19(5), 863–870 (2008).
   PubMed Web of Science ®Google Scholar
• Rastogi A , NissensonAR. Technological advances in renal replacement therapy: five years and beyond. Clin. J. Am. Soc. Nephrol. (4 Suppl. 1), S132–S136 (2009).
   PubMed Web of Science ®Google Scholar
• Jacobs C . Renal replacement therapy by hemodialysis: an overview. Nephrol. Ther.5(4), 306–312 (2009).
   PubMed Web of Science ®Google Scholar
• Rabindranath KS , StrippoliGF, DalyC, RoderickPJ, WallaceS, MacLeodAM. Haemodiafiltration, haemofiltration and haemodialysis for end-stage kidney disease. Cochrane Database Syst. Rev.4, CD006258 (2006).
   Google Scholar
• Shinaberger JH . Quantitation of dialysis: historical perspective. Semin. Dial.14(4), 238–245 (2001).
   PubMed Web of Science ®Google Scholar
• Canaud B . Adequacy target in hemodialysis. J. Nephrol.17(Suppl. 8), S77–S86 (2004).
   PubMedGoogle Scholar
• National Kidney Foundation. KDOQI clinical practice guidelines and clinical practice recommendations for 2006 updates: hemodialysis adequacy. Am. J. Kidney Dis.48(Suppl. 1), S1–S90 (2006).
   PubMed Web of Science ®Google Scholar
• Buszewski B , KesyM, LigorT, AmannA. Human exhaled air analytics: biomarkers of diseases. Biomed. Chromatogr.21(6), 553–566 (2007).
   PubMed Web of Science ®Google Scholar
• Horvath I , LazarZ, GyulaiN, KollaiM, LosonczyG. Exhaled biomarkers in lung cancer. Eur. Respir. J.34(1), 261–275 (2009).
   PubMed Web of Science ®Google Scholar
• Simenhoff ML , BurkeJF, SaukkonenJJ, OrdinarioAT, DotyR. Biochemical profile or uremic breath. N. Engl. J. Med.297(3), 132–135 (1977).
   PubMed Web of Science ®Google Scholar
• Song G , QinT, LiuHet al. Quantitative breath analysis of volatile organic compounds of lung cancer patients. Lung Cancer 67(2), 227–231 (2010).
   PubMed Web of Science ®Google Scholar
• Tisch U , HaickH. Arrays of chemisensitive monolayer-capped metallic nanoparticles for diagnostic breath testing. Rev. Chem. Eng.26, 171–179 (2011).
   Web of Science ®Google Scholar
• Tisch U , HaickH. Nanomaterials for cross-reactive sensor arrays. MRS Bull.35(10), 797–803 (2010).
   Web of Science ®Google Scholar
• Tisch U , AlufY, IonescuRet al. Detection of asymptomatic nigrostriatal dopaminergic lesion in rats by exhaled air analysis using carbon nanotube sensors. ACS Chem. Neurosci. 3(3), 161–166 (2012).
   PubMed Web of Science ®Google Scholar
• Peng S , HakimM, BrozaYYet al. Detection of lung, breast, colorectal, and prostate cancers from exhaled breath using a single array of nanosensors. Br. J. Cancer 103, 542–551 (2010).
   PubMed Web of Science ®Google Scholar
• Peng G , TischU, AdamsOet al. Diagnosing lung cancer in exhaled breath using gold nanoparticles. Nature Nanotechnol. 4(10), 669–673 (2009).
   PubMed Web of Science ®Google Scholar
• Marom O , NakhoulF, TischU, ShibanA, AbassiZ, HaickH. Gold nanoparticle sensors for detecting chronic kidney disease and disease progression. Nanomedicine (Lond.)7(5), 639–650 (2012).
   PubMed Web of Science ®Google Scholar
• Ionescu R , BrozaY, ShaltieliHet al. Detection of multiple sclerosis from exhaled breath using bilayers of polycyclic aromatic hydrocarbons and single-wall carbon nanotubes. ACS Chem. Neurosci. 2(12), 687–693 (2011).
   PubMed Web of Science ®Google Scholar
• Hakim M , BillanS, TischUet al. Diagnosis of head- and neck-cancer from exhaled breath. Br. J. Cancer 104, 1649–1655 (2011).
   PubMed Web of Science ®Google Scholar
• Haick H , HakimM, PatrascuMet al. Sniffing chronic renal failure in rat model by an array of random networks of single-walled carbon nanotubes. ACS Nano 3(5), 1258–1266 (2009).
   PubMed Web of Science ®Google Scholar
• Zilberman Y , IonescuR, FengX, MullenK, HaickH. An array of polycyclic aromatic hydrocarbons and carbon nanotubes for accurate and predictive detection of organic compounds in real-world environmental humidity. ACS Nano5, 6743–6753 (2011).
   PubMed Web of Science ®Google Scholar
• Tisch U , HaickH. Sensors based on monolayer-capped metal nanoparticles. In: Chemical Sensors: Nanostructured Materials (Volume 2). Korotcenkov G (Ed.). Momentum Press, LLC, NY, USA, 141–202 (2010).
   Google Scholar
• Peng G , TrockE, HaickH. Detecting simulated patterns of lung cancer biomarkers by random network of single-walled carbon nanotubes coated with nonpolymeric organic materials. Nano. Lett.8(11), 3631–3635 (2008).
   PubMed Web of Science ®Google Scholar
• Konvalina G , HaickH. Effect of humidity on nanoparticle-based chemiresistors: a comparison between synthetic and real-world samples. ACS Appl. Mater. Interf.4, 317–325 (2012).
   PubMed Web of Science ®Google Scholar
• Wilcoxon F . Individual comparisons by ranking methods. Biometrics Bulletin1(6), 80–83 (1945).
   Google Scholar
• Siegel S . Nonparametric statistics. Am. Stat.11(3), 13–19 (1957).
   Web of Science ®Google Scholar
• McDonald JH . Handbook of Biological Statistics. Sparky House Publishing, MA, USA (2009).
   Google Scholar
• Brereton RG . Chemometrics: Applications of Mathematics and Statistics to Laboratory Systems. Ellis Horwood, Chichester, UK (1990).
   Google Scholar
• Ionescu R , LlobetE, VilanovaXet al. Quantitative analysis of NO2 in the presence of CO using a single tungsten oxide semiconductor sensor and dynamic signal processing. Analyst 127, 1237–1246 (2002).
   PubMed Web of Science ®Google Scholar
• Daugirdas JT , GreeneT, DepnerTAet al. Factors that affect postdialysis rebound in serum urea concentration, including the rate of dialysis: results from the HEMO Study. J. Am. Soc. Nephrol. 15(1), 194–203 (2004).
   PubMed Web of Science ®Google Scholar
• Tattersall JE , DeTakatsD, ChamneyP, GreenwoodRN, FarringtonK. The post-hemodialysis rebound: predicting and quantifying its effect on Kt/V. Kidney Int.50(6), 2094–2102 (1996).
   PubMed Web of Science ®Google Scholar
• Narasimhan LR , GoodmanW, PatelCKN. Correlation of breath ammonia with blood urea nitrogen and creatinine during hemodialysis. Proc. Natl Acad. Sci. USA98(8), 4617–4621 (2001).
   PubMed Web of Science ®Google Scholar
• Ponda MP , QuanZ, MelamedML, RaffA, MeyerTW, HostetterTH. Methylamine clearance by haemodialysis is low. Nephrol. Dial. Transpl.25(5), 1608 (2010).
   PubMed Web of Science ®Google Scholar
• Endre ZH , PickeringJW, StorerMKet al. Breath ammonia and trimethylamine allow real-time monitoring of haemodialysis efficacy. Physiol. Meas. 32(1), 115–130 (2011).
   PubMed Web of Science ®Google Scholar
• Dowty B , CarlisleD, LaseterJL, GonzalezFM. Gas chromatographic mass spectrometric computer analysis of volatile components in blood plasma from hemodialysis patients. Biol. Mass Spectrom.2(3), 142–147 (1975).
   Google Scholar
• Corradi M , GergelovaP, MuttiA. Chapter 10: exhaled volatile organic compounds in nonrespiratory diseases. Eur. Respir. Soc. Monograph.49, 140–151 (2010).
   Google Scholar
• Sprenger KBG , KratzW, LewisAE, StadtmullerU. Kinetic modeling of hemodialysis, hemofiltration and hemodiafiltration. Kidney Int.24, 143–151 (1983).
   PubMed Web of Science ®Google Scholar
• Lee HJ , MeinardiS, PahlMV, VaziriND, BlakeDR. Exposure to potentially toxic hydrocarbons and halocarbons released from the dialyzer and tubing set during hemodialysis. Am. J. Kidney Dis.60(4), 609–616 (2012).
   PubMed Web of Science ®Google Scholar
• Terre‘Blanche G , HeyerN, BerghJJ, MienieLJ, van der Schyf CJ, Harvey BH. The styrene metabolite, phenylglyoxylic acid, induces striatal-motor toxicity in the rat: influence of dose escalation/reduction over time. Neurotox. Res.20(1), 97–101 (2011).
   PubMed Web of Science ®Google Scholar

Website

• ClinicalTrials.gov. Impact of hemodialysis on exhaled volatile organic compounds in end stage renal disease. http://clinicaltrials.gov/ct2/show/NCT01684228?term=NCT01684228&rank=1
   Google Scholar