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Research Article

Genetic Polymorphisms of Drug-Metabolizing Enzymes and Anti-TB Drug-Induced Hepatitis

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Pages 1767-1779 | Published online: 05 Nov 2009

Bibliography

  • Dye C , WattCJ, BleedDM, HosseiniSM, RaviglioneMC: Evolution of tuberculosis control and prospects for reducing tuberculosis incidence, prevalence, and deaths globally.JAMA293 , 2767–2775 (2005).
  • Blumberg HM , BurmanWJ, ChaissonRE et al.: American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: treatment of tuberculosis.Am. J. Respir. Crit. Care Med.167 , 603–662 (2003).
  • Chemotherapy and management of tuberculosis in the United Kingdom: recommendations 1998. Joint Tuberculosis Committee of the British Thoracic Society. Thorax53 , 536–548 (1998).
  • Saukkonen JJ , CohnDL, RM Jasmer et al.: An official ATS statement: hepatotoxicity of antituberculosis therapy. Am. J. Respir. Crit. Care Med.174 , 935–952 (2006).
  • Pande JN , SinghSP, KhilnaniGC, KhilnaniS, TandonRK: Risk factors for hepatotoxicity from antituberculosis drugs: a case–control study.Thorax51 , 132–136 (1996).
  • Sharma SK , BalamuruganA, SahaPK, PandeyRM, MehraNK: Evaluation of clinical and immunogenetic risk factors for the development of hepatotoxicity during antituberculosis treatment.Am. J. Respir. Crit. Care Med.166 , 916–919 (2002).
  • Yee D , ValiquetteC, PelletierM, ParisienI, RocherI, MenziesD: Incidence of serious side effects from first-line antituberculosis drugs among patients treated for active tuberculosis.Am. J. Respir. Crit. Care Med.167 , 1472–1477 (2003).
  • Yew WW , LeungCC: Antituberculosis drugs and hepatotoxicity.Respirology11 , 699–707 (2006).
  • Lee WM : Drug-induced hepatotoxicity.N. Engl. J. Med.349 , 474–485 (2003).
  • Naisbitt DJ , WilliamsDP, PirmohamedM, KitteringhamNR, ParkBK: Reactive metabolites and their role in drug reactions.Curr. Opin. Allergy Clin. Immunol.1 , 317–325 (2001).
  • Huang YS , ChernHD, WJ Su et al.: Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis. Hepatology35 , 883–889 (2002).
  • Shimizu Y , DobashiK, Y Mita et al.: DNA microarray genotyping of N-acetyltransferase 2 polymorphism using carbodiimide as the linker for assessment of isoniazid hepatotoxicity. Tuberculosis (Edinb.)86(5) , 374–381 (2005).
  • Kita T , TanigawaraY, S Chikazawa et al.: N-acetyltransferase2 genotype correlated with isoniazid acetylation in Japanese tuberculous patients. Biol. Pharm. Bull.24 , 544–549 (2001).
  • Hiratsuka M , KishikawaY, TakekumaY et al.: Genotyping of the N-acetyltransferase 2 polymorphism in the prediction of adverse drug reactions to isoniazid in Japanese patients.Drug Metab. Pharmacokinet.17 , 357–362 (2002).
  • Ohno M , YamaguchiI, YamamotoI et al.: Slow N-acetyltransferase 2 genotype affects the incidence of isoniazid and rifampicin-induced hepatotoxicity.Int. J. Tuberc. Lung Dis.4 , 256–261 (2000).
  • Cho HJ , KohWJ, RyuYJ et al.: Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis.Tuberculosis (Edinb.)87 , 551–556 (2007).
  • Higuchi N , TaharaN, YanagiharaK et al.: NAT26A, a haplotype of the N-acetyltransferase 2 gene, is an important biomarker for risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis.World J. Gastroenterol.13 , 6003–6008 (2007).
  • Possuelo LG , CastelanJA, de Brito TC et al.: Association of slow N-acetyltransferase 2 profile and anti-TB drug-induced hepatotoxicity in patients from Southern Brazil. Eur. J. Clin. Pharmacol.64 , 673–681 (2008).
  • Huang YS , ChernHD, SuWJ et al.: Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis.Hepatology37 , 924–930 (2003).
  • Roy B , ChowdhuryA, KunduS et al.: Increased risk of antituberculosis drug-induced hepatotoxicity in individuals with glutathione S-transferase M1 ‘null‘ mutation.J. Gastroenterol. Hepatol.16 , 1033–1037 (2001).
  • Leiro V , Fernandez-VillarA, ValverdeD et al.: Influence of glutathione S-transferase M1 and T1 homozygous null mutations on the risk of antituberculosis drug-induced hepatotoxicity in a Caucasian population.Liver Int.28 , 835–839 (2008).
  • Benichou C : Criteria of drug-induced liver disorders. Report of an international consensus meeting.J. Hepatol.11 , 272–276 (1990).
  • Holden AL : The SNP consortium: summary of a private consortium effort to develop an applied map of the human genome.Biotechniques (Suppl. 22–24) , 26 (2002).
  • Han W , KangD, LeeJE et al.: A haplotype analysis of HER-2 gene polymorphisms: association with breast cancer risk, HER-2 protein expression in the tumor, and disease recurrence in Korea.Clin. Cancer Res.11 , 4775–4778 (2005).
  • Song SH , JunSH, ParkKU et al.: Simultaneous determination of first-line anti-tuberculosis drugs and their major metabolic ratios by liquid chromatography/tandem mass spectrometry.Rapid Commun. Mass Spectrom.21 , 1331–1338 (2007).
  • Urban A , NeukirchenS, JaegerKE: A rapid and efficient method for site-directed mutagenesis using one-step overlap extension PCR.Nucleic Acids Res.25 , 2227–2228 (1997).
  • Hein DW , GrantDM, SimE: Update on consensus arylamine N-acetyltransferase gene nomenclature.Pharmacogenetics10 , 291–292 (2000).
  • Wilke RA , LinDW, RodenDM et al.: Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges.Nat. Rev. Drug Discov.6 , 904–916 (2007).
  • Lee JE , ChoiJH, LeeJH, LeeMG: Gene SNPs and mutations in clinical genetic testing: haplotype-based testing and analysis.Mutat. Res.573 , 195–204 (2005).
  • Zhao H , PfeifferR, GailMH: Haplotype analysis in population genetics and association studies.Pharmacogenomics4 , 171–178 (2003).
  • Lee SY , LeeKA, KiCS et al.: Complete sequencing of a genetic polymorphism in NAT2 in the Korean population.Clin. Chem.48 , 775–777 (2002).
  • Hein DW , DollMA, RustanTD, FergusonRJ: Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: effects of 7 specific NAT2 nucleic acid substitutions.Cancer Res.55 , 3531–3536 (1995).
  • Walgren JL , MitchellMD, ThompsonDC: Role of metabolism in drug-induced idiosyncratic hepatotoxicity.Crit. Rev. Toxicol.35 , 325–361 (2005).
  • Sarich TC , AdamsSP, PetriccaG, WrightJM: Inhibition of isoniazid-induced hepatotoxicity in rabbits by pretreatment with an amidase inhibitor.J. Pharmacol. Exp. Ther.289 , 695–702 (1999).
  • Tafazoli S , MashregiM, O‘BrienPJ: Role of hydrazine in isoniazid-induced hepatotoxicity in a hepatocyte inflammation model.Toxicol. Appl. Pharmacol.229 , 94–101 (2008).

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