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Editorial

Complete Genome Sequencing and Network Modeling to Overcome Trastuzumab Resistance

Pages 1039-1043 | Published online: 12 Aug 2010

Bibliography

  • The human genome at ten. Nature464(7289) , 649–650 (2010).
  • Collins F : Has the revolution arrived?Nature464(7289) , 674–675 (2010).
  • Venter JC : Multiple personal genomes await.Nature464(7289) , 676–677 (2010).
  • Check Hayden E : Human genome at ten: life is complicated.Nature464(7289) , 664–667 (2010).
  • Ledford H : Big science: the cancer genome challenge.Nature464(7291) , 972–974 (2010).
  • Ding L , EllisMJ, LiS et al.: Genome remodelling in a basal-like breast cancer metastasis and xenograft.Nature464(7291) , 999–1005 (2010).
  • Kamangar F , DoresGM, AndersonWF: Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world.J. Clin. Oncol.24(14) , 2137–2150 (2006).
  • Jemal A , SiegelR, WardE et al.: Cancer statistics 2009.CA Cancer J. Clin.59 , 225–249 (2009).
  • Baselga J , SwainSM: Novel anticancer targets: revisiting ERBB2 and discovering ERBB3.Nat. Rev. Cancer9(7) , 463–475 (2009).
  • Slamon DJ , Leyland-JonesB, ShakS et al.: Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.N. Engl. J. Med.344 , 783–792 (2001).
  • van Cutsem E , KangY, ChungH et al.: Efficacy results from the ToGA trial: a Phase III study of trastuzumab added to standard chemotherapy (CT) in first-line human epidermal growth factor receptor 2 (HER2)-positive advanced gastric cancer (GC).J. Clin. Oncol.27(Suppl.) , 18S (2009) (Abstract No. LBA4509).
  • Roukos DH : Targeting gastric cancer with trastuzumab: new clinical practice and innovative developments to overcome resistance.Ann. Surg. Oncol.17 , 14–17 (2010).
  • Petrelli NJ , WinerEP, BrahmerJ et al.: Clinical cancer advances 2009: major research advances in cancer treatment, prevention, and screening – a report from the American Society of Clinical Oncology.J. Clin. Oncol.27(35) , 6052–6069 (2009).
  • Hortobagyi GN : Trastuzumab in the treatment of breast cancer.N. Engl. J. Med.353(16) , 1734–1736 (2005).
  • Dahabreh IJ , LinardouH, SiannisF, FountzilasG, MurrayS: Trastuzumab in the adjuvant treatment of early-stage breast cancer: a systematic review and meta-analysis of randomized controlled trials.Oncologist13(6) , 620–630 (2008).
  • Roukos DH : Personalized cancer diagnostics and therapeutics.Expert Rev. Mol. Diagn.9(3) , 227–229 (2009).
  • Stephens PJ , McBrideDJ, LinML et al.: Complex landscapes of somatic rearrangement in human breast cancer genomes.Nature462(7276) , 1005–1010 (2009).
  • Beroukhim R , MermelCH, PorterD et al.: The landscape of somatic copy-number alteration across human cancers.Nature463(7283) , 899–905 (2010).
  • International Cancer Genome Consortium: International network of cancer genome projects. Nature464 , 993–998 (2010).
  • Ziogas D , RoukosDH: Genetics and personal genomics for personalized breast cancer surgery: progress and challenges in research and clinical practice.Ann. Surg. Oncol.16(7) , 1771–1782 (2009).
  • Roukos DH : Genome-wide association studies and aggressive surgery toward individualized prevention, and improved local control and overall survival for gastric cancer.Ann. Surg. Oncol.16(4) , 795–798 (2009).
  • Rockman MV : Reverse engineering the genotype–phenotype map with natural genetic variation.Nature456 , 738–744 (2008).
  • Bohman T : Mathematics. Emergence of connectivity in networks.Science323(5920) , 1438–1439 (2009).
  • Roukos DH : Novel clinico-genome network modeling for revolutionizing genotype–phenotype-based personalized cancer care.Expert Rev. Mol. Diagn.10(1) , 33–48 (2010).
  • Schadt EE : Molecular networks as sensors and drivers of common human diseases.Nature461(7261) , 218–223 (2009).
  • Roukos DH : Systems medicine: a real approach for future personalized oncology?Pharmacogenomics11(3) , 283–287 (2010).
  • Roukos DH : Bionetworks-based personalized medicine versus comparative-effectiveness research or harmonization of both in cancer management?Expert Rev. Mol. Diagn.10(3) , 247–250 (2010).
  • Weinberg R : Point: hypotheses first.Nature464(7289) , 678 (2010).
  • Roukos DH , KatsiosC, LiakakosT: Genotype-phenotype map and molecular networks: a promising solution in overcoming colorectal cancer resistance to targeted treatment.Expert Rev. Mol. Diagn.10(5) , 541–545 (2010).
  • Hahn WC , WeinbergRA: Modelling the molecular circuitry of cancer.Nat. Rev. Cancer2(5) , 331–341 (2002).
  • Jones S , ZhangX, ParsonsDW: Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.Science321(5897) , 1801–1806 (2008).
  • Roukos DH : Beyond HER2 and trastuzumab: heterogeneity, systems biology, and cancer origin research may guide the future for personalized treatment of very early but aggressive breast cancer.J. Clin. Oncol.28(17) , E279–E280 (2010).

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