Pharmacogenomics, Volume 11, Issue 8 (2010)

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Pharmacogenomics, Volume 11, Issue 8 (2010)

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Editorial

Editorial
Cancer Pharmacogenomics: Do Cancer Cell Lines have the Right Stuff?
J Todd Auman
Pages: 1035-1037
Published online: 12 Aug 2010
First Page PreviewforCancer Pharmacogenomics: Do Cancer Cell Lines have the Right Stuff? | Full Text | References | PDF (514.4 KB)
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Editorial
Complete Genome Sequencing and Network Modeling to Overcome Trastuzumab Resistance
Dimitrios H Roukos
Pages: 1039-1043
Published online: 12 Aug 2010
First Page PreviewforComplete Genome Sequencing and Network Modeling to Overcome Trastuzumab Resistance | Full Text | References | PDF (586.8 KB)
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News & Views

News
News & Views in … Pharmacogenomics
Pages: 1045-1047
Published online: 12 Aug 2010
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News
Research Highlights
Karen-Lise Garm Spindler & Anders Jakobsen
Pages: 1049-1052
Published online: 12 Aug 2010
First Page PreviewforResearch Highlights | Full Text | References | PDF (368.3 KB)
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Research Article

Article
Genetic Variation in Three Candidate Genes and Nicotine Dependence, Withdrawal and Smoking Cessation in Hospitalized Patients
Kim De Ruyck, Kristiaan Nackaerts, Laurence Beels, Joke Werbrouck, Annick De Volder, Marc Meysman, Bihiyga Salhi, Jan Van Meerbeeck & Hubert Thierens
Pages: 1053-1063
Published online: 12 Aug 2010
AbstractforGenetic Variation in Three Candidate Genes and Nicotine Dependence, Withdrawal and Smoking Cessation in Hospitalized Patients | Full Text | References | PDF (683.6 KB) | Supplemental
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Article
Pharmacogenetic Interactions Between ABCB1 and SLCO1B1 Tagging SNPs and the Effectiveness of Statins in the Prevention of Myocardial Infarction
Bas JM Peters, Andrei S Rodin, Olaf H Klungel, Cornelia M van Duijn, Bruno H Ch Stricker, Ruben van‘t Slot, Anthonius de Boer & Anke-Hilse Maitland-van der Zee
Pages: 1065-1076
Published online: 12 Aug 2010
AbstractforPharmacogenetic Interactions Between ABCB1 and SLCO1B1 Tagging SNPs and the Effectiveness of Statins in the Prevention of Myocardial Infarction | Full Text | References | PDF (1,005.4 KB)
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Article
Interethnic Comparisons of Important Pharmacology Genes Using SNP Databases: Potential Application to Drug Regulatory Assessments
Jieming Chen, Yik Ying Teo, Dorothy SL Toh & Cynthia Sung
Pages: 1077-1094
Published online: 12 Aug 2010
AbstractforInterethnic Comparisons of Important Pharmacology Genes Using SNP Databases: Potential Application to Drug Regulatory Assessments | Full Text | References | PDF (3.1 MB) | Supplemental
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Article
Characterization of the Genetic Profile of CYP2C19 in Two South African Populations
Britt I Drögemöller, Galen EB Wright, Dana JH Niehaus, Liezl Koen, Stefanie Malan, Danielle M Da Silva, Renate Hillermann–Rebello, Anthony M La Grange, Mauritz Venter & Louise Warnich
Pages: 1095-1103
Published online: 12 Aug 2010
AbstractforCharacterization of the Genetic Profile of CYP2C19 in Two South African Populations | Full Text | References | PDF (919.2 KB) | Supplemental
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Article
CUL2 and STK11 as Novel Response-Predictive Genes for Neoadjuvant Radiochemotherapy in Esophageal Cancer
Ralf Metzger, Lukas Heukamp, Uta Drebber, Elfriede Bollschweiler, Thomas Zander, Arnulf H Hoelscher & Ute Warnecke-Eberz
Pages: 1105-1113
Published online: 12 Aug 2010
AbstractforCUL2 and STK11 as Novel Response-Predictive Genes for Neoadjuvant Radiochemotherapy in Esophageal Cancer | Full Text | References | PDF (719.5 KB)
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Review

Review Article
Tailored Therapy of ACE Inhibitors in Stable Coronary Artery Disease: Pharmacogenetic Profiling of Treatment Benefit
Jasper J Brugts, Eric Boersma & Maarten L Simoons
Pages: 1115-1126
Published online: 12 Aug 2010
AbstractforTailored Therapy of ACE Inhibitors in Stable Coronary Artery Disease: Pharmacogenetic Profiling of Treatment Benefit | Full Text | References | PDF (965 KB)
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Review Article
Toxicogenetics: Population-Based Testing of Drug and Chemical Safety in Mouse Models
Ivan Rusyn, Daniel M Gatti, Timothy Wilshire, Steven R Kleeberger & David W Threadgill
Pages: 1127-1136
Published online: 12 Aug 2010
AbstractforToxicogenetics: Population-Based Testing of Drug and Chemical Safety in Mouse Models | Full Text | References | PDF (581 KB)
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Review Article
IFN-β Pharmacogenomics in Multiple Sclerosis
Koen Vandenbroeck, Elena Urcelay & Manuel Comabella
Pages: 1137-1148
Published online: 12 Aug 2010
AbstractforIFN-β Pharmacogenomics in Multiple Sclerosis | Full Text | References | PDF (1.7 MB)
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Perspective

Review Article
Realities and Expectations of Pharmacogenomics and Personalized Medicine: Impact of Translating Genetic Knowledge into Clinical Practice
Alessio Squassina, Mirko Manchia, Vangelis G Manolopoulos, Mehmet Artac, Christina Lappa-Manakou, Sophia Karkabouna, Konstantinos Mitropoulos, Maria Del Zompo & George P Patrinos
Pages: 1149-1167
Published online: 12 Aug 2010
AbstractforRealities and Expectations of Pharmacogenomics and Personalized Medicine: Impact of Translating Genetic Knowledge into Clinical Practice | Full Text | References | PDF (915.8 KB)
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Technology Report

Review Article
Detection of KRAS Mutations in Colorectal Carcinoma Patients with an Integrated PCR/Sequencing and Real-Time PCR Approach
Pietro Carotenuto, Cristin Roma, Anna Maria Rachiglio, Fabiana Tatangelo, Carmine Pinto, Fortunato Ciardiello, Oscar Nappi, Vincenzo Iaffaioli, Gerardo Botti & Nicola Normanno
Pages: 1169-1179
Published online: 12 Aug 2010
AbstractforDetection of KRAS Mutations in Colorectal Carcinoma Patients with an Integrated PCR/Sequencing and Real-Time PCR Approach | Full Text | References | PDF (881.3 KB)
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Acknowledgements

Acknowledgements
Page: 1181
Published online: 12 Aug 2010
CitationforAcknowledgements | Full Text | PDF (102.5 KB)
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Erratum

Correction
Erratum
Pages: 1183-1184
Published online: 12 Aug 2010
CitationforErratum | Full Text | PDF (432.3 KB)
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