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Review

Monitoring Kidney Function and Renal Disease in Children Following Transplant

Ajay Parkash Sharma MDa Department of Paediatrics, Children’s Hospital at London Health Science Centre, University of Western Ontario, London, Ontario, Canada Tel.: +1 519 685 8379 Fax.: +1 519 685 [email protected]View further author information
&
Guido Filler MD,PhD,FRCPCb Department of Paediatrics, University of Western Ontario, Children’s Hospital, London Health Science Centre, 800 Commissioners Road East, London, Ontario, Canada, N6A 5W9 Tel.: +1 519 685 8377 Fax.: +1 519 685 [email protected]Correspondence[email protected]
View further author information
Pages 155-163 | Published online: 09 Apr 2009

Bibliography

  • Filler G , PayneRP, OrrbineE, CliffordT, DrukkerA, McLainePN: Changing trends in the referral patterns of pediatric nephrology patients.Pediatr. Nephrol.20, 603–608(2005).
  • Wühl E , SchaeferF: Therapeutic strategies to slow chronic kidney disease progression.Pediatr. Nephrol.23, 705–716(2008).
  • Vikse BE , IrgensLM, LeivestadT, HallanS, IversenBM: Low birth weight increases risk for end-stage renal disease.J. Am. Soc. Nephrol.19, 151–157(2008).
  • Goldenberg RL , CulhaneJF, IamsJD, RomeroR: Epidemiology and causes of preterm birth.Lancet371(9606), 75–84(2008).
  • Filler G , RayarMS, da Silva O, Buffo I, Pepelassis D, Sharma AP: Should prevention of chronic kidney disease start before pregnancy? Int. Urol. Nephrol.40, 483–488(2008).
  • Manley HJ : Disease progression and the application of evidence-based treatment guidelines diagnose it early: a case for screening and appropriate management.J. Manag. Care Pharm.13(9 Suppl. D), S6–S12 (2007).
  • Filler G , SharmaAP: High prevalence of chronic kidney disease in pediatric solid organ transplantation.Pediatr. Transplant. DOI: 10.1111/j.1399-3046.2008.01077.x (2008) (Epub ahead of print).
  • Ojo AO , HeldPJ, PortFKet al.: Chronic renal failure after transplantation of a nonrenal organ.N. Engl. J. Med.349, 931–940(2003).
  • Remuzzi G , PericoN, MaciaM, RuggenentiP: The role of renin–angiotensin–aldosterone system in the progression of chronic kidney disease.Kidney Int. Suppl.99, S57–S65 (2005).
  • Keller G , ZimmerG, MallG, RitzE, AmannK: Nephron number in patients with primary hypertension.N. Engl. J. Med.348, 101–108(2003).
  • L⊘drup AB , KarstoftK, DissingTH, PedersenM, NyengaardJR: Kidney biopsies can be used for estimations of glomerular number and volume: a pig study.Virchows Arch.452(4), 393–403(2008).
  • Rahn KH , HeidenreichS, BrücknerD: How to assess glomerular function and damage in humans.J. Hypertens.17, 309–317(1999).
  • Smith HW , GoldringW, ChasisH: The measurement of tubular excretory mass, effective blood flow and filtration rate in the normal human kidney.J. Clin. Invest.17, 263–270(1938).
  • Hostetter TH , OlsonJL, RennkeHG, VenkatachalamMA, BrennerBM: Hyperfiltration in remnant nephrons: a potentially adverse response to renal ablation.Am. J. Physiol.241, F85–F93 (1981).
  • Filler G , BrowneR, SeikalyMG: Glomerular filtration rate as a putative ‘surrogate end-point’ for renal transplant clinical trials in children.Pediatr. Transplant.7, 18–24(2003).
  • Jennings DL , KalusJS, ColemanCI, ManierskiC, YeeJ: Combination therapy with an ACE inhibitor and an angiotensin receptor blocker for diabetic nephropathy: a meta-analysis.Diabet. Med.24, 486–493(2007).
  • Peeters P , VanholderR: Therapeutic interventions favorably influencing delayed and slow graft function in kidney transplantation: mission impossible?Transplantation85(Suppl. 7), S31–S37 (2008).
  • Djamali A : Oxidative stress as a common pathway to chronic tubulointerstitial injury in kidney allografts.Am. J. Physiol. Renal Physiol.293(2), F445–F455 (2007).
  • Hubsch H , MontanéB, AbitbolCet al.: Recurrent focal glomerulosclerosis in pediatric renal allografts: the Miami experience.Pediatr. Nephrol.20(2), 210–216(2005).
  • Al Aly Z , AbbasS, MooreE, DialloO, HauptmanPJ, BastaniB: The natural history of renal function following orthotopic heart transplant.Clin. Transplant19, 683–689(2005).
  • Bharat W , ManlhiotC, McCrindleBW, Pollock-BarzivS, DipchandAI: The profile of renal function over time in a cohort of pediatric heart transplant recipients.Pediatr. Transplant. DOI: 10.1111/j.1399-3046.2007.00848.x (2007) (Epub ahead of print).
  • Neu AM , HoPL, FineRN, FurthSL, FivushBA: Tacrolimus vs. cyclosporine A as primary immunosuppression in pediatric renal transplantation: a NAPRTCS study.Pediatr. Transplant.7, 217–222(2003).
  • McCulloch MI , BurgerH, SpearmanCWet al.: Nephrotoxic effects of immunosuppressant therapy in pediatric liver transplant recipients.Transplant. Proc.37, 1220–1223(2005).
  • Loo RM , AriyarajahV, OhC, ShenL, AwMM, PrabhakaranK: Comparison between effects of cyclosporine and tacrolimus on glomerular filtration rate in pediatric post-orthotopic liver transplant patients.Pediatr. Transplant.10, 55–59(2006).
  • Arora-Gupta N , DaviesP, McKiernanP, KellyDA: The effect of long-term calcineurin inhibitor therapy on renal function in children after liver transplantation.Pediatr. Transplant.8, 145–150(2004).
  • Mention K , Lahoche-ManucciA, BonnevalleMet al.: Renal function outcome in pediatric liver transplant recipients.Pediatr. Transplant.9, 201–207(2005).
  • Richards AN , WestfallBB, BottPA: Renal excretion of inulin, creatinine and xylose in normal dogs.Proc. Soc. Exper. Boil Med.32, 73–87(1934).
  • Smith HW : Measurement of filtration rate: In: The Kidney: Structure and Function. Oxford University Press, NY, USA 39–62(1951).
  • Malamos B , DontasAS, KoutrasDAet al.: The determination of glomerular filtration-rate in clinical practice.Lancet1(7444), 943–945(1966).
  • Pastore A , BernardiniS, Dello Strologo L, Rizzoni G, Cortese C, Federici G: Simultaneous determination of inulin and p-aminohippuric acid in plasma and urine by reversed-phase high-performance liquid chromatography. J. Chromatogr. B Biomed. Sci. Appl.751, 187–191(2001).
  • Russell CD : Optimum sample times for single-injection, multisample renal clearance methods.J. Nucl. Med.34, 1761–1765(1993).
  • Houlihan C , JenkinsM, OsickaT, ScottA, ParkinD, JerumsG: A comparison of the plasma disappearance of iohexol and 99mTc-DTPA for the measurement of glomerular filtration rate (GFR) in diabetes.Aust. NZ J. Med.29, 693–700(1999).
  • Frennby B , SternerG, AlmenT, ChaiCM, JonssonBA, ManssonS: Clearance of iohexol, chromium-51-ethylenediaminetetraacetic acid, and creatinine for determining the glomerular filtration rate in pigs with normal renal function: comparison of different clearance techniques.Acad. Radiol.3, 651–659(1996).
  • Itoh K , TsushimaS, TsukamotoE, TamakiN: Accuracy of plasma sample methods for determination of glomerular filtration rate with 99mTc-DTPA.Ann. Nucl. Med.16, 39–44(2002).
  • Peters AM , HendersonBL, LuiD, BlunkettM, CosgriffPS, MyersMJ: Appropriate corrections to glomerular filtration rate and volume of distribution based on the bolus injection and single-compartment technique.Physiol. Meas.20, 313–327(1999).
  • Chantler C , BarrattTM: Estimation of glomerular rate from plasma clearance of 51-chromium edetic acid.Arch. Dis. Child.47, 613–617(1972).
  • Chantler C , GarnettES, ParsonsV, VeallN: Glomerular filtration rate measurement in man by the single injection methods using 51Cr-EDTA.Clin. Sci.37, 169–180(1969).
  • Filler G , WittI, PriemF, EhrichJH, JungK: Are cystatin C and β2-microglobulin better markers than serum creatinine for prediction of a normal glomerular filtration rate in pediatric subjects?Clin. Chem.43, 1077–1078(1997).
  • Shemesh O , GolbetzH, KrissJP, MyersBD: Limitations of creatinine as a filtration marker in glomerulopathic patients.Kidney Int.28, 830–838(1985).
  • Filler G , PriemF, LepageNet al.: β-trace protein, cystatin C, β(2)-microglobulin, and creatinine compared for detecting impaired glomerular filtration rates in children.Clin. Chem.48, 729–736(2002).
  • Russell CD : Optimum sample times for single-injection, multi-sample renal clearance methods.J. Nucl. Med.34, 1761–1765(1993)
  • Oberhausen E : Investigation of renal clearance in nuclear medicine (author‘s transl).Radiologe21(12), 548–552(1981).
  • Heilbron DC , HollidayMA, Al-DahwiA, KoganBA: Expressing glomerular filtration rate in children.Pediatr. Nephrol.5, 5–11(1991).
  • Popper H , MandelE: Filtrations- und Reabsorptionsleitung in der Nierenpathologie.Ergeb. Inn. Med. Kinderheilkd.53, 685–694(1937).
  • Heymsfield SB , ArteagaC, McManusC, SmithJ, MoffittS: Measurement of muscle mass in humans: validity of the 24-hour urinary creatinine method.Am. J. Clin. Nutr.37, 478–594(1983).
  • Vinge E , LindergardB, Nilsson-EhleP, GrubbA: Relationship among serum cystatin C, serum creatinine, lean tissue mass and glomerular filtration rate in healthy adults.Scand. J. Clin. Lab. Invest.59, 587–592(1999).
  • Pham-Huy A , LeonardM, LepageN, HaltonJ, FillerG: Measuring glomerular filtration rate with cystatin C and β-trace protein in children with spina bifida.J. Urol.169, 2312–2315(2003).
  • Thomassen SA , JohannesenIL, ErlandsenEJ, AbrahamsenJ, RandersE: Serum cystatin C as a marker of the renal function in patients with spinal cord injury.Spinal Cord40, 524–528(2002).
  • Brion LP , BoeckMA, GauthierB, NussbaumMP, SchwartzGJ: Estimation of glomerular filtration rate in anorectic adolescents.Pediatr. Nephrol.3, 16–21(1989).
  • Fitch CD , SintonDW: A study of creatine metabolism in diseases causing muscle wasting.J. Clin. Invest.43, 444–452(1964).
  • Shannon JA : The renal excretion of creatinine in man.J. Clin. Invest.14, 403–410(1935).
  • Horio M , OritaY: Comparison of Jaffe rate assay and enzymatic method for the measurement of creatinine clearance.Nippon Jinzo Gakkai Shi38, 296–299(1996).
  • Arant BS : Estimating glomerular filtration rate in infants.J. Pediatr.104, 890–892(1984).
  • Proficiency Testing Survey, Creatinine. College of American Pathologists, Northfield IL, USA 29–30(1995).
  • Olsen NV , LadefogedS, Feldt-RasmussenBet al.: The effects of cimetidine on creatinine excretion glomerular filtration rate and tubular function in renal transplant recipients:Scand. J. Clin. Lab. Invest.49, 155–159(1989).
  • Roubenoff R , DrewH, MoyerMet al.: Oral cimetidine improves the accuracy and precision of creatinine clearance in lupus nephritis.Ann. Int. Med.113, 501–506(1990).
  • Hellerstein S , ErwinP, WaradyBA: The cimetidine protocol: a convenient, accurate, and inexpensive way to measure glomerular filtration rate.Pediatr. Nephrol.18, 71–72(2003).
  • Schwartz GJ , BrionLP, SpitzerA: The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children and adolescents.Pediatr. Clin. N. Am.34, 571–90(1987).
  • Seikaly MG , BrowneR, BajajG, ArantBS Jr: Limitations to body length/serum creatinine ratio as an estimate of glomerular filtration in children. Pediatr. Nephrol.10, 709–711(1996).
  • Hellerstein S , AlonU, WaradyBA: Creatinine for estimation of glomerular filtration rate.Pediatr. Nephrol.6, 507–11(1992).
  • Filler G , FosterJ, AckerA, LepageN, AkbariA, EhrichJH: The Cockcroft-Gault formula should not be used in children.Kidney Int.67, 2321–2324(2005).
  • Jung K : Low-molecular-mass proteins in serum and their relationship to the glomerular filtration rate.Nephron47, 160–168(1987).
  • Grubb A , SimonsenO, SturfeltG, TruedssonL, ThysellH: Serum concentration of cystatin C, factor D and β2-microglobulin as a measure of glomerular filtration rate.Acta Med. Scand.218, 499–503(1985).
  • Jacobsson B , LignelidH, BergerheimUS: Transthyretin and cystatin C are catabolized in proximal tubular epithelial cells and the proteins are not useful as markers for renal cell carcinomas.Histopathology26, 559–564(1995).
  • Simonsen O , GrubbA, ThysellH: The blood serum concentration of cystatin C (γ-trace) as a measure of the glomerular filtration rate.Scand. J. Clin. Lab. Invest.45, 97–101(1985).
  • Löfberg H , GrubbAO: Quantitation of γ-trace in human biological fluids: indications for production in the central nervous system.Scand. J. Clin. Lab. Invest.39, 619–626(1979).
  • Bökenkamp A , van Wijk JA, Lentze MJ, Stoffel-Wagner B: Effect of corticosteroid therapy on serum cystatin C and β2-microglobulin concentrations. Clin. Chem.48, 1123–1126(2002).
  • Kyhse-Andersen J , SchmidtC, NordinGet al.: Serum cystatin C, determined by a rapid, automated particle-enhanced turbidimetric method, is a better marker than serum creatinine for glomerular filtration rate.Clin. Chem.40, 1921–1926(1994).
  • Newman DJ , ThakkarH, EdwardsRGet al.: Serum cystatin C measured by automated immunoassay: a more sensitive marker of changes in GFR than serum creatinine.Kidney Int.47, 312–318(1995).
  • Finney H , NewmanDJ, GruberW, MerleP, PriceCP: Initial evaluation of cystatin C measurement by particle-enhanced immunonephelometry on the Behring nephelometer systems (BNA, BN II).Clin. Chem.43, 1016–1022(1997).
  • Erlandsen EJ , RandersE, KristensenJH: Evaluation of the Dade Behring N latex cystatin C assay on the Dade Behring nephelometer II system.Scand. J. Clin. Lab. Invest.59, 1–8(1999).
  • Mussap M , RuzzanteN, VaragnoloM, PlebaniM: Quantitative automated particle-enhanced immunonephelometric assay for the routinary measurement of human cystatin C.Clin. Chem. Lab. Med.36, 859–865(1998).
  • Norlund L , FexG, LankeJet al.: Reference intervals for the glomerular filtration rate and cellproliferation markers: serum cystatin C and serum β2-microglobulin/cystatin C-ratio.Scand. J. Clin. Lab. Invest.57, 463–470(1997).
  • Harmoinen A , YlinenE, Ala-HouhalaM, JanasM, KailaM, KouriT: Reference intervals for cystatin C in pre- and full-term infants and children.Pediatr. Nephrol.15, 105–108(2000).
  • Fischbach M , GraffV, TerzicJ, BergèreV, OudetM, HamelG: Impact of age on reference values for serum concentration of cystatin C in children.Pediatr. Nephrol.17, 104–106(2002).
  • Stickle D , ColeB, HockK, HruskaKA, ScottMG: Correlation of plasma concentrations of cystatin C and creatinine to inulin clearance in a pediatric population.Clin. Chem.44, 1334–1338(1998).
  • Bökenkamp A , DomanetzkiM, ZinckR, SchumannG, ByrdD, BrodehlJ: Cystatin C – a new marker of glomerular filtration rate in children independent of age and height.Pediatrics101, 875–881(1998).
  • Filler G , PriemF, VollmerI, GellermannJ, JungK: Diagnostic sensitivity of serum cystatin for impaired glomerular filtration rate.Pediatr. Nephrol.13, 501–505(1999).
  • Ylinen EA , Ala-HouhalaM, HarmoinenAP, KnipM: Cystatin C as a marker for glomerular filtration rate in pediatric patients.Pediatr. Nephrol.13, 506–509(1999).
  • Kilpatrick ES , KeevilBG, AddisonGM: Does adjustment of GFR to extracellular fluid volume improve the clinical utility of cystatin C?Arch. Dis. Child.82, 499–502(2000).
  • Vinge E , LindergardB, Nilsson-EhleP, GrubbA: Relationships among serum cystatin C, serum creatinine, lean tissue mass and glomerular filtration rate in healthy adults.Scand. J. Clin. Lab. Invest.59, 587–592(1999).
  • Woitas RP , Stoffel-WagnerB, FlommersfeldSet al.: Correlation of serum concentrations of cystatin C and creatinine to inulin clearance in liver cirrhosis.Clin. Chem.46, 712–715(2000).
  • Sharma AP , KathiraveluA, NadarajahR, YasinA, FillerG: Body mass does not have a clinically relevant effect on cystatin C eGFR in children.Nephrol. Dial. Transplant.24(2), 470–474(2008).
  • Thomassen SA , JohannesenIL, ErlandsenEJ, AbrahamsenJ, RandersE: Serum cystatin C as a marker of the renal function in patients with spinal cord injury.Spinal Cord40, 524–528(2002).
  • Filler G , LepageN: Should the Schwartz formula for estimation of GFR be replaced by cystatin C formula?Pediatr. Nephrol.18, 981–985(2003).
  • White C , AkbariA, HussainNet al.: Estimating glomerular filtration rate in kidney transplantation: a comparison between serum creatinine and cystatin C-based methods.J. Am. Soc. Nephrol.16, 3763–3770(2005).
  • Dharnidharka VR , KwonC, StevensG: Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis.Am. J. Kidney Dis.40, 221–226(2002).
  • Plebani M , Dall‘AmicoR, MussapMet al.: Is serum cystatin C a sensitive marker of glomerular filtration rate (GFR)? A preliminary study on renal transplant patients.Ren. Fail.20, 303–309(1998).
  • Risch L , BlumbergA, HuberA: Rapid and accurate assessment of glomerular filtration rate in patients with renal transplants using serum cystatin C.Nephrol. Dial. Transplant.14, 1991–1996(1999).
  • Bökenkamp A , OzdenN, DieterichC, SchumannG, EhrichJH, BrodehlJ: Cystatin C and creatinine after successful kidney transplantation in children.Clin. Nephrol.52, 371–376(1999).
  • Le Bricon T , ThervetE, BenlakehalM, BousquetB, LegendreC, ErlichD: Changes in plasma cystatin C after renal transplantation and acute rejection in adults.Clin. Chem.45, 2243–2249(1999).
  • Le Bricon T , ThervetE, FroissartMet al.: Plasma cystatin C is superior to 24-h creatinine clearance and plasma creatinine for estimation of glomerular filtration rate 3 months after kidney transplantation.Clin. Chem.46, 1206–1207(2000).
  • Herget-Rosenthal S , TraboldS, HuesingJ, HeemannU, PhilippT, KribbenA: Cystatin C – an accurate marker of glomerular filtration rate after renal transplantation?Transp. Int.13, 285–289(2000).
  • Bogdanovic R : Diabetic nephropathy in children and adolescents.Pediatr. Nephrol.23, 507–25(2008).
  • Mortensen HB , MarinelliK, NorgaardKet al.: A nation-wide cross-sectional study of urinary albumin excretion rate, arterial blood pressure and blood glucose control in Danish children with Type 1 diabetes mellitus. Danish Study Group of Diabetes in Childhood.Diabet. Med.7, 887–897(1990).
  • Bangstad HJ , Dahl-JorgensenK, KjaersgaardP, MevoldK, HanssenKF: Urinary albumin excretion rate and puberty in non-diabetic children and adolescents.Acta Paediatr.82, 857–862(1993).
  • Garg AX , ClarkWF, SalvadoriMet al.: Microalbuminuria three years after recovery from Escherichia coli O157 hemolytic uremic syndrome due to municipal water contamination.Kidney Int.67, 1476–1482(2005).
  • Cobenas CJ , AlconcherLF, SpizzirriAP, RahmanRC: Long-term follow-up of Argentinean patients with hemolytic uremic syndrome who had not undergone dialysis.Pediatr. Nephrol.22, 1343–1347(2007).
  • Danne T , KordonouriO, HovenerG, WeberB: Diabetic angiopathy in children.Diabet. Med.14, 1012–1025(1997).
  • Holl RW , GrabertM, ThonA, HeinzeE: Urinary excretion of albumin in adolescents with Type 1 diabetes: persistent versus intermittent microalbuminuria and relationship to duration of diabetes, sex, and metabolic control.Diabetes Care22, 1555–1560(1999).
  • Lou-Meda R , OakesRS, GilstrapJN, WilliamsCG, SieglerRL: Prognostic significance of microalbuminuria in postdiarrheal hemolytic uremic syndrome.Pediatr. Nephrol.22, 117–120(2007).
  • Terpstra WF , MayJF, SmitAJ, de Graeff PA, Crijns HJ: Microalbuminuria is related to marked end organ damage in previously untreated, elderly hypertensive patients. Blood Press11, 84–90(2002).
  • Kitzmueller E , VecseiA, PichlerJet al.: Changes of blood pressure and left ventricular mass in pediatric renal transplantation.Pediatr. Nephrol.19, 1385–1389(2004).
  • Soergel M : Is ABPM clinically useful after pediatric solid organ transplantation?Pediatr. Transplant.8, 433–436(2004).
  • Morgan H , KhanI, HashmiA, HebertD, McCrindleBW, BalfeJW: Ambulatory blood pressure monitoring after renal transplantation in children.Pediatr. Nephrol.16, 843–847(2001).
  • Soergel M : Is ABPM clinically useful after pediatric solid organ transplantation?Pediatr. Transplant.8, 433–436(2004).
  • Lingens N , DobosE, LemmerB, ScharerK: Nocturnal blood pressure elevation in transplanted pediatric patients.Kidney Int. Suppl.55, S175–S176 (1996).
  • Crawford DH , EndreZH, AxelsenRAet al.: Universal occurrence of glomerular abnormalities in patients receiving liver transplants.Am. J. Kidney Dis.19, 339–344(1992).
  • Birk PE , StannardKM, KonradHBet al.: Surveillance biopsies are superior to functional studies for the diagnosis of acute and chronic renal allograft pathology in children.Pediatr. Transplant.8, 29–38(2004).

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