11,338
Views
1
CrossRef citations to date
0
Altmetric
Review

Prescribing Naloxone for Opioid Overdose Intervention

Pages 197-208 | Received 28 Nov 2017, Accepted 23 Feb 2018, Published online: 18 Apr 2018

References

  • Wilkerson RG , KimHK , WindsorTA , MareinissDP . The opioid epidemic in the United States . Emerg. Med. Clin. North Am.34 ( 2 ), e1 – e23 ( 2016 ).
  • Fischer B , RehmJ . Revisiting the ‘paradigm shift’ in opioid use: developments and implications 10 years later . Drug Alcohol Rev.37 ( Suppl. 1 ), S199 – S202 ( 2017 ).
  • Kolodny A , CourtwrightDT , HwangCSet al. The prescription opioid and heroin crisis: a public health approach to an epidemic of addiction . Annu. Rev. Public. Health36 , 559 – 574 ( 2015 ).
  • Rudd RA , AleshireN , ZibbellJE , GladdenRM . Increases in drug and opioid overdose deaths – United States, 2000–2014 . MMWR Morb. Mortal. Wkly Rep.64 ( 50–51 ), 1378 – 1382 ( 2016 ).
  • Rudd RA , SethP , DavidF , SchollL . Increases in drug and opioid-involved overdose deaths – United States, 2010–2015 . MMWR Morb. Mortal. Wkly Rep.65 ( 50–51 ), 1445 – 1452 ( 2016 ).
  • Peterson AB , GladdenRM , DelcherCet al. Increases in fentanyl-related overdose deaths – Florida and Ohio, 2013–2015 . MMWR Morb. Mortal. Wkly Rep.65 ( 33 ), 844 – 849 ( 2016 ).
  • Hawk KF , VacaFE , D’OnofrioG . Reducing fatal opioid overdose: prevention, treatment and harm reduction strategies . Yale J. Biol. Med.88 ( 3 ), 235 – 245 ( 2015 ).
  • Kim HK , NelsonLS . Reducing the harm of opioid overdose with the safe use of naloxone: a pharmacologic review . Expert Opin. Drug Saf.14 ( 7 ), 1137 – 1146 ( 2015 ).
  • Davis C . Naloxone for Community Opioid Overdose Reversal.Center for Public Health Law Research , PA, USA ( 2015 ). http://prescribetoprevent.org/wp2015/wp-content/uploads/PHLRKnowledgeAsset_Naloxone_FINALfull_8June15.pdf
  • Compton WM , VolkowND , ThrockmortonDC , LurieP . Expanded access to opioid overdose intervention: research, practice, and policy needs . Ann. Intern. Med.158 ( 1 ), 65 – 66 ( 2013 ).
  • Wheeler E , JonesTS , GilbertMK , DavidsonPJ . Opioid overdose prevention programs providing naloxone to laypersons – United States, 2014 . MMWR Morb. Mortal. Wkly Rep.64 ( 23 ), 631 – 635 ( 2015 ).
  • Doe-Simkins M , WalleyAY , EpsteinA , MoyerP . Saved by the nose: bystander-administered intranasal naloxone hydrochloride for opioid overdose . Am. J. Public Health99 ( 5 ), 788 – 791 ( 2009 ).
  • Rando J , BroeringD , OlsonJE , MarcoC , EvansSB . Intranasal naloxone administration by police first responders is associated with decreased opioid overdose deaths . Am. J. Emerg. Med.33 ( 9 ), 1201 – 1204 ( 2015 ).
  • Fisher R , O’DonnellD , RayB , RusyniakD . Police officers can safely and effectively administer intranasal naloxone . Prehosp. Emerg. Care20 ( 6 ), 675 – 680 ( 2016 ).
  • Strang J , McDonaldR , TasB , DayE . Clinical provision of improvised nasal naloxone without experimental testing and without regulatory approval: imaginative shortcut or dangerous bypass of essential safety procedures?Addiction111 ( 4 ), 574 – 582 ( 2016 ).
  • Edwards ET , EdwardsES , DavisE , MulcareM , WiklundM , KelleyG . Comparative usability study of a novel auto-injector and an intranasal system for naloxone delivery . Pain Ther.4 ( 1 ), 89 – 105 ( 2015 ).
  • NARCAN® (naloxone hydrochloride) nasal spray, package insert . Adapt Pharma, Inc. , PA, USA ( 2017 ).
  • Krieter P , ChiangN , GyawSet al. Pharmacokinetic properties and human use characteristics of an FDA-approved intranasal naloxone product for the treatment of opioid overdose . J. Clin. Pharmacol.56 ( 10 ), 1243 – 1253 ( 2016 ).
  • Green TC , DauriaEF , BratbergJ , DavisCS , WalleyAY . Orienting patients to greater opioid safety: models of community pharmacy-based naloxone . Harm Reduct. J.12 , 25 ( 2015 ).
  • Coffin PO , BeharE , RoweCet al. Nonrandomized intervention study of naloxone coprescription for primary care patients receiving long-term opioid therapy for pain . Ann. Intern. Med.165 ( 4 ), 245 – 252 ( 2016 ).
  • Wilson CG , RodriguezF , CarringtonAC , FaganEB . Development of a targeted naloxone coprescribing program in a primary care practice . J. Am. Pharm. Assoc.57 ( 2S ), S130 – S134 ( 2017 ).
  • Takeda MY , KatzmanJG , DoleEet al. Co-prescription of naloxone as a universal precautions model for patients on chronic opioid therapy–observational study . Subst. Abus.37 ( 4 ), 591 – 596 ( 2016 ).
  • Katzman J , TakedaMY , BhattSR , BalaschM , GreenbergN . Lives saved with take-home naloxone for patients in medication-assisted treatment . Addict. Med.11 ( 3 ), 1 ( 2017 ).
  • Green TC , BowmanSE , RayM , McKenzieM , LordSE , RichJD . Development of an incarceration-specific overdose prevention video: staying alive on the outside . Health Educ. J.74 ( 5 ), 627 – 637 ( 2015 ).
  • Green TC , RayM , BowmanSE , McKenzieM , RichJD . Two cases of intranasal naloxone self-administration in opioid overdose . Subst. Abus.35 ( 2 ), 129 – 132 ( 2014 ).
  • Knezevich A . Maryland jail inmates to be trained to administer overdose drug ( 2016 ). http://www.baltimoresun.com/news/maryland/bs-md-naloxone-jails-20161225-story.html
  • Albert M , McCaigLF , UddinS . Emergency Department Visits for Drug Poisoning: United States, 2008–2011.US Department of Health & Human Services , MD, USA ( 2015 ).
  • Weiss AJ , ElixhauserA , BarrettML , SteinerCA , BaileyMK , O’MalleyL . Opioid-Related Inpatient Stays and Emergency Department Visits by State, 2009–2014. HCUP Statistical Brief #219.Agency for Healthcare Research and Quality , MD, USA ( 2016 ). http://www.hcup-us.ahrq.gov/reports/statbriefs/sb219-Opioid-Hospital-Stays-ED-Visits-by-State.pdf
  • Yokell MA , DelgadoMK , ZallerND , WangNE , McGowanSK , GreenTC . Presentation of prescription and nonprescription opioid overdoses to US emergency departments . JAMA Intern. Med.174 ( 12 ), 2034 – 2037 ( 2014 ).
  • Braden JB , RussoJ , FanMYet al. Emergency department visits among recipients of chronic opioid therapy . Arch. Intern. Med.170 ( 16 ), 1425 – 1432 ( 2010 ).
  • Hasegawa K , BrownDFM , TsugawaY , CamargoCAJr . Epidemiology of emergency department visits for opioid overdose: a population-based study . Mayo Clin. Proc.89 ( 4 ), 462 – 471 ( 2014 ).
  • Brady JE , DiMaggioCJ , KeyesKM , DoyleJJ , RichardsonLD , LiG . Emergency department utilization and subsequent prescription drug overdose death . Ann. Epidemiol.25 ( 8 ), 613 – 619.e612 ( 2015 ).
  • Hoppe JA , NelsonLS , PerroneJet al. Opioid prescribing in a cross section of US emergency departments . Ann. Emerg. Med.66 ( 3 ), 253 – 259.e251 ( 2015 ).
  • Weiner SG , RajaAS , BittnerJCet al. Opioid-related policies in New England emergency departments . Acad. Emerg. Med.23 ( 9 ), 1086 – 1090 ( 2016 ).
  • Samuels EA , DwyerK , MelloMJ , BairdJ , KelloggAR , BernsteinE . Emergency department-based opioid harm reduction: moving physicians from willing to doing . Acad. Emerg. Med.23 ( 4 ), 455 – 465 ( 2016 ).
  • Lacroix L , ThurgurL , OrkinAM , PerryJJ , StiellIG . Emergency physicians’ attitudes and perceived barriers to the implementation of take-home naloxone programs in Canadian emergency departments . CJEM20 ( 1 ), 46 – 52 ( 2017 ).
  • Gupta R , ShahND , RossJS . The rising price of naloxone – risks to efforts to stem overdose deaths . N. Engl. J. Med.375 ( 23 ), 2213 – 2215 ( 2016 ).
  • Davis CS , CarrD . Legal changes to increase access to naloxone for opioid overdose reversal in the United States . Drug Alcohol Depend.157 , 112 – 120 ( 2015 ).
  • Davis C , CarrD . State legal innovations to encourage naloxone dispensing . J. Am. Pharm. Assoc.57 ( 2S ), S180 – S184 ( 2017 ).
  • Dowell D , HaegerichTM , ChouR . CDC guideline for prescribing opioids for chronic pain – United States, 2016 . JAMA315 ( 15 ), 1624 – 1645 ( 2016 ).
  • Kestler A , BuxtonJ , MecklingGet al. Factors associated with participation in an emergency department-based take-home naloxone program for at-risk opioid users . Ann. Emerg. Med.69 ( 3 ), 340 – 346 ( 2017 ).
  • Wilson JD , SpicynN , MatsonP , AlvanzoA , FeldmanL . Internal medicine resident knowledge, attitudes, and barriers to naloxone prescription in hospital and clinic settings . Subst. Abus.37 ( 3 ), 480 – 487 ( 2016 ).
  • Barry T , KlimasJ , TobinH , EganM , BuryG . Opiate addiction and overdose: experiences, attitudes, and appetite for community naloxone provision . Br. J. Gen. Pract.67 ( 657 ), e267 – e273 ( 2017 ).
  • Behar E , RoweC , SantosGMet al. Acceptability of naloxone co-prescription among primary care providers treating patients on long-term opioid therapy for pain . J. Gen. Intern. Med.32 ( 3 ), 291 – 295 ( 2017 ).
  • Behar E , RoweC , SantosGM , SantosN , CoffinPO . Academic detailing pilot for naloxone prescribing among primary care providers in San Francisco . Fam. Med.49 ( 2 ), 122 – 126 ( 2017 ).
  • Bounthavong M , HarveyMA , WellsDLet al. Trends in naloxone prescriptions prescribed after implementation of a National Academic Detailing Service in the Veterans Health Administration: a preliminary analysis . J. Am. Pharm. Assoc.57 ( 2S ), S68 – S72 ( 2017 ).
  • Nielsen S , PeacockA , LintzerisN , BrunoR , LaranceB , DegenhardtL . Knowledge of opioid overdose and attitudes to supply of take-home naloxone among people with chronic noncancer pain prescribed opioids . Pain Med.19 ( 3 ), 533 – 540 ( 2017 ).
  • Behar E , RoweC , SantosGM , MurphyS , CoffinPO . Primary care patient experience with naloxone prescription . Ann. Fam. Med.14 ( 5 ), 431 – 436 ( 2016 ).
  • Bazazi AR , ZallerND , FuJJ , RichJD . Preventing opiate overdose deaths: examining objections to take-home naloxone . J. Health Care Poor Underserved21 ( 4 ), 1108 – 1113 ( 2010 ).
  • Winograd RP , DavisCS , NiculeteM , OlivaE , MartielliRP . Medical providers’ knowledge and concerns about opioid overdose education and take-home naloxone rescue kits within Veterans Affairs health care medical treatment settings . Subst. Abus.38 ( 2 ), 135 – 140 ( 2017 ).
  • Kim D , IrwinKS , KhoshnoodK . Expanded access to naloxone: options for critical response to the epidemic of opioid overdose mortality . Am. J. Public Health99 ( 3 ), 402 – 407 ( 2009 ).
  • Seal KH , DowningM , KralAHet al. Attitudes about prescribing take-home naloxone to injection drug users for the management of heroin overdose: a survey of street-recruited injectors in the San Francisco Bay Area . J. Urban Health80 ( 2 ), 291 – 301 ( 2003 ).
  • Jones JD , CampbellA , MetzVE , ComerSD . No evidence of compensatory drug use risk behavior among heroin users after receiving take-home naloxone . Addict. Behav.71 , 104 – 106 ( 2017 ).
  • Enteen L , BauerJ , McLeanRet al. Overdose prevention and naloxone prescription for opioid users in San Francisco . J. Urban Health87 ( 6 ), 931 – 941 ( 2010 ).
  • Wakeman SE , BowmanSE , McKenzieM , JeronimoA , RichJD . Preventing death among the recently incarcerated: an argument for naloxone prescription before release . J. Addict. Dis.28 ( 2 ), 124 – 129 ( 2009 ).
  • Binswanger IA , SternMF , DeyoRAet al. Release from prison – a high risk of death for former inmates . N. Engl. J. Med.356 ( 2 ), 157 – 165 ( 2007 ).
  • Binswanger IA , BlatchfordPJ , MuellerSR , SternMF . Mortality after prison release: opioid overdose and other causes of death, risk factors, and time trends from 1999 to 2009 . Ann. Intern. Med.159 ( 9 ), 592 – 600 ( 2013 ).
  • Davis C , ChangS , CarrD , Hernandez-DelgadoH . Legal Interventions to Reduce Overdose Mortality: Naloxone Access and Overdose Good Samaritan Laws.The Network for Public Health Law , MN, USA ( 2017 ).
  • Morton KJ , HarrandB , FloydCCet al. Pharmacy-based statewide naloxone distribution: a novel “top-down, bottom-up” approach . J. Am. Pharm. Assoc.57 ( 2S ), S99 – S106.e105 ( 2017 ).
  • WHO . Community Management of Opioid Overdose.Geneva, Switzerland ( 2014 ). http://www.who.int/substance_abuse/publications/management_opioid_overdose/en/
  • Substance Abuse and Mental Health Administration . Opioid Overdose Prevention Toolkit.MD, USA ( 2016 ).
  • American Academy of Pain Management . Co-prescribing of naloxone in conjunction with opioid therapy ( 2016 ). http://blog.aapainmanage.org/co-prescribing-of-naloxone-in-conjunction-with-opioid-therapy/
  • American Society of Addiction Medicine . Public Policy Statement on the Use of Naloxone for the Prevention of Drug Overdose Deaths.ASAM , MD, USA ( 2014 ).
  • American Society of Addiction Medicine . The ASAM National Practice Guideline for the Use of Medications in the Treatment of Addiction Involving Opioid Use.ASAM , MD, USA ( 2015 ). http://www.asam.org/quality-practice/guidelines-and-consensus-documents/npg
  • Davis CS , BurrisS , BeletskyL , BinswangerI . Co-prescribing naloxone does not increase liability risk . Subst. Abus.37 ( 4 ), 498 – 500 ( 2016 ).
  • Bohnert AS , ValensteinM , BairMJet al. Association between opioid prescribing patterns and opioid overdose-related deaths . JAMA305 ( 13 ), 1315 – 1321 ( 2011 ).
  • Dunn KM , SaundersKW , RutterCMet al. Opioid prescriptions for chronic pain and overdose: a cohort study . Ann. Intern. Med.152 ( 2 ), 85 – 92 ( 2010 ).
  • Zedler B , XieL , WangLet al. Risk factors for serious prescription opioid-related toxicity or overdose among Veterans Health Administration patients . Pain Med.15 ( 11 ), 1911 – 1929 ( 2014 ).
  • Miller M , BarberCW , LeathermanSet al. Prescription opioid duration of action and the risk of unintentional overdose among patients receiving opioid therapy . JAMA Intern. Med.175 ( 4 ), 608 – 615 ( 2015 ).
  • Larochelle MR , LiebschutzJM , ZhangF , Ross-DegnanD , WharamJF . Opioid prescribing after nonfatal overdose and association with repeated overdose: a cohort study . Ann. Intern. Med.164 ( 1 ), 1 – 9 ( 2016 ).
  • Boscarino JA , KirchnerHL , PitcavageJMet al. Factors associated with opioid overdose: a 10-year retrospective study of patients in a large integrated health care system . Subst. Abuse Rehabil.7 , 131 – 141 ( 2016 ).
  • Kerensky T , WalleyAY . Opioid overdose prevention and naloxone rescue kits: what we know and what we don’t know . Addict. Sci. Clin. Pract.12 ( 1 ), 4 ( 2017 ).
  • Webster LR , WebsterRM . Predicting aberrant behaviors in opioid-treated patients: preliminary validation of the opioid risk tool . Pain Med.6 ( 6 ), 432 – 442 ( 2005 ).
  • Butler SF , FernandezK , BenoitC , BudmanSH , JamisonRN . Validation of the revised Screener and Opioid Assessment for Patients with Pain (SOAPP-R) . J. Pain9 ( 4 ), 360 – 372 ( 2008 ).
  • Substance Abuse and Mental Health Services Administration . Substance Abuse Treatment for Persons with Co-Occurring Disorders.MD, USA ( 2005 ).
  • Devries J , RafieS , PolstonG . Implementing an overdose education and naloxone distribution program in a health system . J. Am. Pharm. Assoc.57 ( 2S ), S154 – S160 ( 2017 ).
  • Mueller SR , KoesterS , GlanzJM , GardnerEM , BinswangerIA . Attitudes toward naloxone prescribing in clinical settings: a qualitative study of patients prescribed high dose opioids for chronic non-cancer pain . J. Gen. Intern. Med.32 ( 3 ), 277 – 283 ( 2017 ).
  • Wickramatilake S , ZurJ , Mulvaney-DayN , Campopiano von KlimoM , SelmiE , HarwoodH . How states are tackling the opioid crisis . Public Health Rep.132 ( 2 ), 171 – 179 ( 2017 ).
  • Strang J , McDonaldR , AlqurshiA , RoyallP , TaylorD , ForbesB . Naloxone without the needle – systematic review of candidate routes for non-injectable naloxone for opioid overdose reversal . Drug Alcohol Depend.16316 – 23 ( 2016 ).
  • McDonald R , LorchU , WoodwardJet al. Pharmacokinetics of concentrated naloxone nasal spray for opioid overdose reversal: Phase I healthy volunteer study . Addiction113 ( 3 ), 484 – 493 ( 2017 ).
  • Tylleskar I , SkulbergAK , NilsenT , SkarraS , JansookP , DaleO . Pharmacokinetics of a new, nasal formulation of naloxone . Eur. J. Clin. Pharmacol.73 ( 5 ), 555 – 562 ( 2017 ).