Mechanical factors activate ß‐catenin‐dependent oncogene expression in APC^1638N/+ mouse colon

References

• Anderson , CB , Neufeld , KL and White , RL . 2002 . “Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon.” . Proc. Natl. Acad. Sci. U.S.A. , 99 (13) : 8683 – 8688 .
   PubMed Web of Science ®Google Scholar
• Andreu , P . 2005 . “Crypt‐restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.” . Development , 132 (6) : 1443 – 1451 .
   PubMed Web of Science ®Google Scholar
• Aoki , K . 2007 . “Chromosomal instability by [beta]‐catenin//TCF transcription in APC or [beta]‐catenin mutant cells.” . Oncogene, , 26 (24) : 3511 – 3520 .
   PubMed Web of Science ®Google Scholar
• Avvisato , CL , Yang , X , Shah , S , Hoxter , B , Li , W , Gaynor , R , Pestell , R , Tozeren , A and Byers , SW . 2007 . “Mechanical force modulates global gene expression and beta‐catenin signaling in colon cancer cells.” . J. Cell. Sci. , 120 (15) : 2672 – 2682 .
   PubMed Web of Science ®Google Scholar
• Bain , J , McLauchlan , H , Elliott , M and Cohen , P . 2003 . “The specificities of protein kinase inhibitors: an update.” . Biochem. J. , 371 (Pt 1) : 199 – 204 .
   PubMedGoogle Scholar
• Basson , MD . 2003 . “Paradigms for mechanical signal transduction in the intestinal epithelium.” . Digestion , 68 (4) : 217 – 225 .
   PubMed Web of Science ®Google Scholar
• Bissell , MJ , Kenny , PA and Radisky , DC . 2005 . “Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes.” . Cold Spring Harbor Symposia on Quantitative Biology , 70 (1) : 343 – 356 .
   PubMedGoogle Scholar
• Blake , RA , Broome , MA , Liu , X , Wu , J , Gishizky , M , Sun , L and Courtneidge , SA . 2000 . “SU6656 a selective Src family kinase inhibitor, used to probe growth factor signaling.” . Mol. Cell. Biol. , 20 (23) : 9018 – 9027 .
   PubMed Web of Science ®Google Scholar
• Boucher , Y and Jain , RK . 1992 . “Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse.” . Cancer Res. , 52 (18) : 5110 – 5114 .
   PubMed Web of Science ®Google Scholar
• Brabletz , T , Jung , A , Spaderna , S , Hlubek , F and Kirchner , T . 2005 . “Migrating cancer stem cells—an integrated concept of malignant tumour progression.” . Nat. Rev. Cancer , 5 (9) : 744 – 749 .
   PubMed Web of Science ®Google Scholar
• Brouzes , E , Supatto , W and Farge , E . 2004 . “Is mechano‐sensitive expression of twist involved in mesoderm formation?” . Biol. Cell , 96 (7) : 471 – 477 .
   PubMed Web of Science ®Google Scholar
• Chen , CS , Alonso , JL , Ostuni , E , Whitesides , GM and Ingber , DE . 2004 . “Cell shape provides global control of focal adhesion assembly?” . Biochem. Biophys. Res. Commun. , 307 (2) : 355 – 361 .
   Web of Science ®Google Scholar
• Draviam , VM , Shapiro , I , Aldridge , B and Sorger , PK . 2006 . “Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1‐or APC‐depleted cells.” . EMBO J. , 25 (12) : 2814 – 2827 .
   PubMed Web of Science ®Google Scholar
• Farge , E . 2003 . “Mechanical induction of twist in the Drosophila foregut/stomodeal primordium.” . Curr. Biol. , 13 (16) : 1365 – 1377 .
   PubMed Web of Science ®Google Scholar
• Fodde , R and Brabletz , T . 2007 . “Wnt/beta‐catenin signaling in cancer stemness and malignant behavior.” . Curr. Opin. Cell Biol. , 19 (2) : 150 – 158 .
   PubMed Web of Science ®Google Scholar
• Fodde , R . 1994 . “A targeted chain‐termination mutation in the mouse Apc gene results in multiple intestinal tumors.” . Proc. Natl. Acad. Sci. U.S.A. , 91 (19) : 8969 – 8973 .
   PubMed Web of Science ®Google Scholar
• Fodde , R . 2001 . “Mutations in the APC tumour suppressor gene cause chromosomal instability.” . Nat. Cell Biol. , 3 (4) : 433 – 438 .
   PubMed Web of Science ®Google Scholar
• Fre , S , Vignjevic , D , Schoumacher , M , Duffy , SL , Janssen , K‐P , Robine , S and Louvard , D . 2008 . “Epithelial morphogenesis and intestinal cancer: new insights in signaling mechanisms.” . Adv. Cancer Res. , 100 : 85 – 111 .
   PubMed Web of Science ®Google Scholar
• Gregorieff , A and Clevers , H . 2005 . “Wnt signaling in the intestinal epithelium: from endoderm to cancer.” . Genes Dev. , 19 (8) : 877 – 890 .
   PubMed Web of Science ®Google Scholar
• Hao , XP , Pretlow , TG , Rao , JS and Pretlow , TP . 2001 . “Beta‐catenin expression is altered in human colonic aberrant crypt foci.” . Cancer Res. , 61 (22) : 8085 – 8088 .
   PubMed Web of Science ®Google Scholar
• Harris , TJC and Peifer , M . 2005 . “Decisions, decisions: Beta‐catenin chooses between adhesion and transcription.” . Trends Cell Biol. , 15 (5) : 234 – 237 .
   PubMed Web of Science ®Google Scholar
• Harzmann , R , Schubert , GE , Gericke , D , Altenahr , E and Bichler , KH . 1983 . “Morphology of the urinary bladder following long‐term experimental irritation of the urothelium.” . Urol. Int. , 38 (3) : 166 – 172 .
   PubMed Web of Science ®Google Scholar
• Hayashi , S , Rubinfeld , B , Souza , B , Polakis , P , Wieschaus , E and Levine , AJ . 1997 . “A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down‐regulates beta‐catenin but its zygotic expression is not essential for the regulation of armadillo.” . Proc. Natl. Acad. Sci. U.S.A. , 94 (1) : 242 – 247 .
   PubMed Web of Science ®Google Scholar
• He , T‐C , Sparks , AB , Rago , C , Hermeking , H , Zawel , L , da Costa , LT , Morin , PJ , Vogelstein , B and Kinzler , KW . 1998 . “Identification of c‐MYC as a target of the APC pathway.” . Science , 281 (5382) : 1509 – 1512 .
   PubMed Web of Science ®Google Scholar
• Hens , J , Wilson , K , Dann , P , Chen , X , Horowitz , M and Wysolmerski , J . 2005 . “TOPGAL mice show that the canonical Wnt signaling pathway is active during bone development and growth and is activated by mechanical loading in vitro.” . J. Bone Miner. Res. , 20 (7) : 1103 – 1113 .
   PubMed Web of Science ®Google Scholar
• Hirokawa , M . 1997 . “Pressure stimulates proliferation and DNA synthesis in rat intestinal epithelial cells.” . Life Sci. , 61 (7) : 667 – 672 .
   PubMed Web of Science ®Google Scholar
• Hirokawa , M . 2001 . “Loading of mechanical pressure activates mitogen‐activated protein kinase and early immediate gene in intestinal epithelial cells.” . Dig. Dis. Sci. , 46 (9) : 1993 – 2003 .
   PubMed Web of Science ®Google Scholar
• Howe , LR , Watanabe , O , Leonard , J and Brown , AM . 2003 . “Twist is up‐regulated in response to Wnt1 and inhibits mouse mammary cell differentiation.” . Cancer Res. , 63 (8) : 1906 – 1913 .
   PubMed Web of Science ®Google Scholar
• Iwamoto , M , Ahnen , DJ , Franklin , WA and Maltzman , TH . 2000 . “Expression of beta‐catenin and full‐length APC protein in normal and neoplastic colonic tissues.” . Carcinogenesis , 21 (11) : 1935 – 1940 .
   PubMed Web of Science ®Google Scholar
• Le Beyec , J , Xu , R , Lee , S‐Y , Nelson , CM , Rizki , A , Alcaraz , J and Bissell , MJ . 2007 . “Cell shape regulates global histone acetylation in human mammary epithelial cells.” . Exp. Cell Res. , 313 (14) : 3066 – 3075 .
   PubMed Web of Science ®Google Scholar
• Lockhart , PB , Norris , CM and Pulliam , C . 1998 . “Dental factors in the genesis of squamous cell carcinoma of the oral cavity.” . Oral Oncol. , 34 (2) : 133 – 139 .
   PubMed Web of Science ®Google Scholar
• Luebeck , EG and Moolgavkar , SH . 2002 . “Multistage carcinogenesis and the incidence of colorectal cancer.” . Proc. Natl. Acad. Sci. U.S.A. , 99 (23) : 15095 – 15100 .
   PubMed Web of Science ®Google Scholar
• Ma , L , Teruya‐Feldstein , J and Weinberg , RA . 2007 . “Tumour invasion and metastasis initiated by microRNA‐10b in breast cancer.” . Nature (London) , 449 (7163) : 682 – 688 .
   PubMed Web of Science ®Google Scholar
• Munne , A , Fabre , M , Marinoso , ML , Gallen , M , Real , FX and for the Colon Cancer Team at IMAS . 1999 . “Nuclear beta‐catenin in colorectal tumors: to freeze or not to freeze?” . J. Histochem. Cytochem. , 47 (8) : 1089 – 1094 .
   PubMed Web of Science ®Google Scholar
• Noria , S , Cowan , DB , Gotlieb , AI and Langille , BL . 1999 . “Transient and steady‐state effects of shear stress on endothelial cell adherens junctions.” . Circ. Res. , 85 (6) : 504 – 514 .
   PubMed Web of Science ®Google Scholar
• Padera , T , Stoll , B , Tooredman , J , Capen , D , Tomaso , Ed and Jain , R . 2004 . “Cancer cells compress intratumour vessels.” . Nature (London) , 427 (6976) : 695
   PubMed Web of Science ®Google Scholar
• Paszek , MJ . 2005 . “Tensional homeostasis and the malignant phenotype.” . Cancer Cells , 8 (3) : 241 – 254 .
   Web of Science ®Google Scholar
• Piedra , J , Martinez , D , Castano , J , Miravet , S , Dunach , M and de Herreros , AG . 2001 . “Regulation of beta‐catenin structure and activity by tyrosine phosphorylation.” . J. Biol. Chem. , 276 (23) : 20436 – 20443 .
   PubMed Web of Science ®Google Scholar
• Radisky , DC . 2005 . “Rac1b and reactive oxygen species mediate MMP‐3‐induced EMT and genomic instability.” . Nature (London) , 436 (7047) : 123 – 127 .
   PubMed Web of Science ®Google Scholar
• Rasband, WS, (1997–2007). ImageJ /, U. S. National Institutes of Health, Bethesda, Maryland, USA. http://rsb.info.nih.gov/ij (http://rsb.info.nih.gov/ij)
   Google Scholar
• Robinson , JA . 2006 . “Wnt/beta‐catenin signaling is a normal physiological response to mechanical loading in bone.” . J. Biol. Chem. , 281 (42) : 31720 – 31728 .
   PubMed Web of Science ®Google Scholar
• Roura , S , Miravet , S , Piedra , J , de Herreros , AG and Dunach , M . 1999 . “Regulation of e‐cadherin/catenin association by tyrosine phosphorylation.” . J. Biol. Chem. , 274 (51) : 36734 – 36740 .
   PubMed Web of Science ®Google Scholar
• Sawada , Y , Tamada , M , Dubin‐Thaler , B J , Cherniavskaya , O , Sakai , R , Tanaka , S and Sheetz , MP . 2006 . “Force sensing by mechanical extension of the Src family kinase substrate p130Cas.” . Cell , 127 (5) : 1015 – 1026 .
   PubMed Web of Science ®Google Scholar
• Sena , P , Saviano , M , Monni , S , Losi , L , Roncucci , L , Marzona , L and Pol , AD . 2006 . “Subcellular localization of beta‐catenin and APC proteins in colorectal preneoplastic and neoplastic lesions.” . Cancer Lett. , 241 (2) : 203 – 212 .
   PubMed Web of Science ®Google Scholar
• Smits , R . 1999 . “Apc1638T: A mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development.” . Genes Dev. , 13 (10) : 1309 – 1321 .
   PubMed Web of Science ®Google Scholar
• Takahashi , S , Ikeda , Y , Kimoto , N , Okochi , E , Cui , L , Nagao , M , Ushijima , T and Shirai , T . 2000 . “Mutation induction by mechanical irritation caused by uracil‐induced urolithiasis in Big Blue® rats.” . Mutat Res. , 447 (2) : 275 – 280 .
   PubMed Web of Science ®Google Scholar
• Takahashi , Y , Bontoux , M and Le Douarin , NM . 1991 . “Epithelio—mesenchymal interactions are critical for Quox 7 expression and membrane bone differentiation in the neural crest derived mandibular mesenchyme.” . EMBO J. , 10 (9) : 2387 – 2393 .
   PubMed Web of Science ®Google Scholar
• Tighe , A , Johnson , VL and Taylor , SS . 2004 . “Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability.” . J. Cell. Sci. , 117 (26) : 6339 – 6353 .
   PubMed Web of Science ®Google Scholar
• Tillmann , T . 1997 . “Subcutaneous soft tissue tumours at the site of implanted microchips in mice.” . Exp. Toxicol. Pathol. , 49 (3–4) : 197 – 200 .
   PubMedGoogle Scholar
• Tsukamoto , K , Ariga , H , Mantyh , C , Pappas , TN , Yanagi , H , Yamamura , T and Takahashi , T . 2007 . “Luminally released serotonin stimulates colonic motility and accelerates colonic transit in rats.” . Am. J.Physiol. , 293 (1) : R64 – 69 .
   Google Scholar
• Ukropec , JA , Hollinger , MK and Woolkalis , MJ . 2002 . “Regulation of VE‐cadherin linkage to the cytoskeleton in endothelial cells exposed to fluid shear stress.” . Exp. Cell Res. , 273 (2) : 240 – 247 .
   PubMed Web of Science ®Google Scholar
• Vitetta , L , Sali , A , Little , P and Mrazek , L . 2000 . “Gallstones and gall bladder carcinoma.” . ANZJ. Surg. , 70 (9) : 667 – 673 .
   Google Scholar
• Walsh , MF , Woo , RK , Gomez , R and Basson , MD . 2004 . “Extracellular pressure stimulates colon cancer cell proliferation via a mechanism requiring PKC and tyrosine kinase signals.” . Cell Prolif , 37 (6) : 427 – 441 .
   PubMed Web of Science ®Google Scholar
• Wang , Y , Botvinick , EL , Zhao , Y , Berns , MW , Usami , S , Tsien , RY and Chien , S . 2005 . “Visualizing the mechanical activation of Src.” . Nature (London) , 434 (7036) : 1040 – 1045 .
   PubMed Web of Science ®Google Scholar
• Wheeler , DL . 2003 . “Database resources of the National Center for Biotechnology.” . Nucleic Acids Res. , 31 (1) : 28 – 33 .
   PubMed Web of Science ®Google Scholar
• Yang , Z . 2007 . “Up‐regulation of gastric cancer cell invasion by Twist is accompanied by N‐cadherin and fibronectin expression.” . Biochem. Biophys. Res. Commun. , 358 (3) : 925 – 930 .
   PubMed Web of Science ®Google Scholar
• Young , TB , Ford , CN and Brandenburg , JH . 1986 . “An epidemiologic study of oral cancer in a statewide network.” . Am. J. Otolaryngol. , 7 (3) : 200 – 208 .
   PubMed Web of Science ®Google Scholar