Continuous progesterone exposure associated with high contraction frequency in human term myometrial strips

References

• Csapo A. ‘Progesterone block’. Am J Anat 1956; 98: 273–91
   PubMedGoogle Scholar
• Beck P, Adler P, Szlachter N, Goldsmit L T, Steinetz B G, Weiss G. Synergistical effect of human relaxin and progesterone on human myometrial contractions. Int J Gynaecol Obstet 1982; 20: 141–4
   Google Scholar
• Barnafi L, Larraquibel R. The in vitro effect of progesterone and oestrogens on the spontaneous and oxytocin-induced activity of the human myometrium. Acta Endocrinol 1974; 76: 172–7
   Google Scholar
• Löfgren M, Hoist J, BÄckstrÖm T. Effects in vitro of progesterone and two 5α-reduced progestins, 5α-pregnane-3,20-dione and 5α-pregnane-3α-ol-20-one, on contracting human myometrium at term. Acta Obstet Gynecol Scand 1992; 71: 28–33
   PubMed Web of Science ®Google Scholar
• Milewich L, Gomez-Sanchez C, Madden J D, MacDonald P C. Isolation and characterization of 5α-pregnane-3,20-dione and progesterone in peripheral blood of pregnant women. Measurement throughout pregnancy. Gynecol Invest 1975; 6: 291–306
   PubMedGoogle Scholar
• Stoa K F, Bessen A. Identification and quantitation of 5α-pregnanedione in human pregnancy plasma. J Steroid Bio-chem Mol Biol 1975; 6: 21–5
   Google Scholar
• Löfgren M, BÄckstrÖm T, Joelsson I. Decrease in serum concentration of 5α-pregnane-3,20-dione prior to spontaneous labor. Acta Obstet Gynecol Scand 1988; 67: 467–70
   Web of Science ®Google Scholar
• Sanyal M, Villee C. Production and physiologic effects of progesterone metabolites in pregnant and pseudopregnant rats. Endocrinol. 1973; 92: 83–93
   Google Scholar
• Rahman S, Billiar R B, Little M. Induction of uteroglobin in rabbits by progestagens, estradiol 17p and ACTH. Biol Reprod 1992; 12: 305–14
   Google Scholar
• Milewich L, Smith S L, MacDonald P C. Nonrespiratory functions of the human lung: In vitro metabolism of tritium-labeled progesterone and pregnenolone. J Clin Endocrinol Metab 1980; 50: 507–15
   Google Scholar
• Arafat E S, Hargrove J T. Sedative and hypnotic effects of oral administration of micronized progesterone may be Progestins and myometrium 191 mediated through its metabolites. Am J Obstet Gynecol 1988; 159: 1203–9
   PubMed Web of Science ®Google Scholar
• Norberg L, Wahlstrom G, BÄckstrÖm T. The anesthetic potency of 3α-hydroxy-5α-Pregnan-20-one and 3α-hydroxy-5α-Pregnan-20-one determined with an intravenous EEG-threshold method in male rats. Acta Pharmacol et Toxicol 1987; 61: 42–7
   Google Scholar
• Karavolas H J, Hodges R D. Steroids and neuronal activity. Ciba Foundation Symposium 153. John Wiley & Sons, New York 1990; 22–46
   Google Scholar
• Saitoh H, Hirato K, Yanaihara T, Nakayama T. A study of 5α-reductase in human fetal brain. Endocrinol Japan 1982; 29: 461–7
   Google Scholar
• Kubli-Garfias C, Hoyo-Vadillo C, Lopez-Nieto E, Ponce-Monter H. Inhibition of spontaneous contractions of the rat pregnant uterus by progesterone metabolites. Proc West Pharmacol Soc 1983; 115–8
   Google Scholar
• Bryman I, Nordstrom A, Lindblom B. Effects of PGE2 and PGF2a on the simulation by noradrenalin and oxytocin of human cervical muscle activity at term. Experientia 1985; 41: 1446–7
   Google Scholar
• Wikland M, Lindblom B, Wilhelmson L, Wiquist N. Oxytocin, prostaglandins and contractility of the human uterus at term pregnancy. Acta Obstet Gynecol Scand 1982; 61: 467–72
   PubMed Web of Science ®Google Scholar
• Löfgren M, BÄckstrÖm T. Progesterone concentrations in maternal and fetal serum are lower during functional dystocia than in normal labor. Obstet Gynecol 1992; 79: 752–9
   Google Scholar
• Kahn-Dawood F, Dawood Y. Estrogen and progesterone receptor and hormone levels in human myometrium and placenta in term pregnancy. Am J Obstet Gynecol 1984; 150: 501–5
   Google Scholar
• Gee K W. Steroid modulation of the GABA/benzodiazepine receptor-linked chloride ionophore. Mol Neurobiol 1988; 2: 219–31
   Google Scholar
• Maggi M, Fiscella A, Magini A, Giannini S, Fantoni G, Orlando C, et al. Steroid modulation of oxytocin/vasopressin receptors in uterus. J Steroid Biochem 1990; 36(suppl)5S
   Google Scholar
• Schumacher M, Cohuni H, Pfaff D W, McEwen B C. Behavioral effects of progesterone associated with rapid modulation of oxytocin receptors. Science 1990; 250: 691–4
   Google Scholar
• Haluska G J, Stanczyk F Z, Cook M J, Novy M J. Temporal changes in uterine activity and prostaglandin response to RU486 in Rhesus Macaques in late gestation. Am J Obstet Gynecol 1987; 157: 1489–95
   Google Scholar
• Wolf J P, Sinosich M, Anderson T L, Ulmann A, Baulieu E E, Hodgen G D. Progesterone antagonist (RU486) for cervical dilation, labor induction, and delivery in monkeys: Effectiveness in combination with oxytocin. Am J Obstet Gynecol 1989; 160: 45–7
   Google Scholar