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Acta Oto-Laryngologica Volume 93, 1982 - Issue 1-6
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Original Article

Ototoxicity of the Anticancer Drug Cisplatin:An Experimental Study

Y. Nakai Department of Otolaryngology, Osaka City University Medical School, Osaka, Japan
,
K. Konishi Department of Otolaryngology, Osaka City University Medical School, Osaka, Japan
,
K. C. Chang Department of Otolaryngology, Osaka City University Medical School, Osaka, Japan
,
K. Ohashi Department of Otolaryngology, Osaka City University Medical School, Osaka, Japan
,
N. Morisaki Department of Otolaryngology, Osaka City University Medical School, Osaka, Japan
,
Y. Minowa Department of Otolaryngology, Osaka City University Medical School, Osaka, Japan
&
A. Morimoto Department of Otolaryngology, Osaka City University Medical School, Osaka, Japan
 show all
Pages 227-232 | Received 20 Apr 1981, Published online: 08 Jul 2009

References

  • Brummett R. E., Smith C. A., Ueno Y., Cameron S., Richter R. Delayed effects of ethacrynic acid on the stria vascularis of the guinea pig. Acta Otolaryngol (Stockh) 1977; 83: 98
  • Fleischman R. W., Standnicki S. W., Ethier M. F., Schaeppi U. Ototoxicity of cis-dichlorodiamine Platinum (II) in the guinea pig. Toxicol ApplPharmacol 1975; 33: 320
  • Helson L., Okonkwo E., Anton L., Cvitkovic E. Cis-Platinum ototoxicity. Clinical Toxicology 1978; 13: 469
  • Lundquist P. G., Wersäll J. Kanamycin-induced changes in cochlear hair cells of the guinea pig. Z Zell-forsch 1966; 72: 543
  • Nakai Y. Electron microscopic study of the inner ear after ethacrynic acid intoxication. Pract Oto-Rhino-Laryngol 1971; 33: 366
  • Nakai Y., Nakai S. Ototoxic effect of nitromin and some congenital deaf animal cochlea. An Electron microscopical study. Arch Klin OhrNas Kehlkopfheilk 1971; 198: 325
  • Nakai Y. Combined effect of 3', 4'-dideoxykana-mycin B and potent diuretics on the cochlea. (A scanning and transmission electron microscopic evaluation.). Laryngoscope 1977; 87: 1548
  • Nakai Y., Zushi K., Chang K.C., Yagi H., Toki-Moto T. An experimental study on the progres-siveness of cochlear damage by aminoglycoside drug. Acta Otolatyngol (Stockh). 1980, In Press
  • Standnicki S. W., Fleisehman R. W., Schaeppi U., Merriam P. Cu-dichlorodiamine Platinum (II) (NSC-119875). Hearing loss and other toxic effect in rhesus monkeys. Cancer Chemother Rep 1975; 59: 467

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