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Research Article

Transforming Growth Factor β2 Level is Elevated in Neurons of Alzheimer's Disease Brains

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Pages 168-175 | Published online: 08 Apr 2010

REFERENCES

  • Böttner, M., Krieglstein, K., & Unsicker, K. (2000). The transforming growth factor-βs: Structure, signaling, and roles in nervous system development and functions. Journal of Neurochemistry, 75, 2227–2240.
  • Chao, C. C., Hu, S., Frey, W. H., Ala, T. A., Tourtellotte, W. W., & Peterson, P. K. (1994). Transforming growth factor β in Alzheimer's disease. Clinical and Diagnostic Laboratory Immunology, 1, 109–110.
  • Flanders, K. C., Lippa, C. F., Smith, T. W., Pollen, D. A., & Sporn, M. B. (1995). Altered expression of transforming growth factor-beta in Alzheimer's disease. Neurology, 45, 1561–1569.
  • Hardy, J., & Selkoe, D. J. (2002). The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science, 297, 353–356.
  • Hashimoto, Y., Chiba, T., Yamada, M., Nawa, M., Kanekura, K., Suzuki, H., (2005). Transforming growth factor beta2 is a neuronal cell death-inducing ligand for amyloid-β precursor protein. Molecular and Cell Biology, 25, 9304–9317.
  • Hashimoto, Y., Nawa, M., Chiba, T., Aiso, S., Nishimoto, I., & Matsuoka, M. (2006). Transforming growth factor beta2 autocrinally mediates neuronal cell death induced by amyloid-beta. Journal of Neuroscience Research, 83, 1039–1047.
  • Krieglstein, K., Richter, S., Farkas, L., Schuster, N., Dunker, N., Oppenheim, R. W., (2000). Reduction of endogenous transforming growth factors β prevents ontogenetic neuron death. Nature Neuroscience, 3, 1085–1090.
  • Krieglstein, K., Suter-Crazzolara, C., Fischer, W. H., & Unsicker, K. (1995). TGF-β superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP + toxicity. EMBO Journal, 14, 736–742.
  • Massagué, J., Blain, S. W., & Lo, R. S. (2000). TGFβ signaling in growth control, cancer, and heritable disorders. Cell, 103, 295–309.
  • Matsuoka, M., Hashimoto, Y., Aiso, S., & Nishimoto, I. (2006). Humanin and Colivelin: Neuronal-death-suppressing peptides for Alzheimer's disease and ALS. CNS Drug Reviews, 12, 113–122.
  • Mattson, M. P. (2000). Apoptosis in neurodegenerative disorders. Nature Reviews Molecular Cell Biology, 1, 120–130.
  • Poulson, K. T., Armanini, M. P., Klein, R. D., Hynes, M. A., Phillips, H. S., Rosenthal, A. (1994). TGF-β2 and TGF-β3 are potent survival factors for midbrain dopaminergic neurons. Neuron, 13, 1245–1252.
  • Schuster, N., & Krieglstein, K. (2000). Mechanisms of TGF-β-mediated apoptosis. Cell and Tissue Research, 307, 1–14.
  • Van de Lest, C. H., Versteeg, E. M., Veerkamp, J. H., & Van Kuppevelt. (1995). Elimination of autofluorescence in immunofluorescence microscopy with digital image processing. Journal of Histochemistry and Cytochemistry, 43, 727–730.

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