4
Views
5
CrossRef citations to date
0
Altmetric
Original Article

The Molecular Mode of Brain Mrna Processing Damage Followed by the Suppression of Post-Transcriptional Poly(A) Synthesis with Cordycepin

&
Pages 53-67 | Received 15 Jan 1988, Accepted 22 Dec 1989, Published online: 07 Jul 2009

References

  • Alonso A., Winter H., Krieg L. Isolation and purification of hnRNA from the nuclei and hnRNP particles of mammalian cells. Biochemica et Biophysica Acta 1981; 652: 72–81
  • Brown T. L., Rosen J. M. Isolation and charaterization of milk protein nuclear RNAs from rat mammary gland. Analytical Biochemistry 1986; 153: 211–220
  • Clawson R. I., Smuckler E. A. Poly(A) containing and lacking messenger RNAs and their nuclear precursors in eucaryotic cells. A review. Journal of Theoretical Biology 1982; 95: 607–613
  • Curry J. B., Hersh R. T. Cytoplasmic water soluble proteins of rat brain tissue. Biochemical and Biophysical Research Communications 1962; 6: 415–419
  • Doel M., Carey N. H. Artificially deadenylated messenger RNA for rat liver albumin promotes an active translation in Xenopus laevis oocytes. Cell 1976; 8: 51–58
  • O'Farrell P. Z., Goodman H. M., O'Farrell P. H. Two-dimensional electrophoretic mapping of the SV40 virus induced proteins isolated form cytoplasm of HeLa and 3T3 cells. Cell 1977; 12: 1133–1142
  • Greenwood F. C., Hunter W. M. The in vitro iodation of highly purified proteins and polypeptides: an improved chemical technique using a simple inorgangic medium. Biochemical Journal 1963; 89: 114–123
  • Huez G., Marbaix G., Birny A. Globin deadenylated mRNA template activity in the ribonuclease pre-treated rabbit reticulocyte lysate. Nature 1977; 266: 473–475
  • Katinakis P. K., Slater A., Burdon R. H. Poly(A) lacking messenger RNAs in eucaryotic cells. FEBS Letters 1980; 116: 1–7
  • Kuznetsov D. A. mRNA metabolism in rat brain cortical cells during the normal ontogenesis. Cand. Biol. Sci. I. M. Sechenov School of Medicine Press, Moscow (in Russian) 1981; 54–69, (Ph.D.) Thesis, 1st Moscow
  • Kuznetsov D. A., Khasigov P. Z. Metabolic heterogenity of rat brain polysomal mRNA: half-lifes and processing time values durijg the normal ontogenesis. Biokhimia 1981; 46: 1526–1530, (in Russian)
  • Kuznetsov D. A., Khasigov P. Z., Musaev N. I. Quantitative estimation of unlabelled cordycepin in the acid soluble pool isolated from rat brain tissue after a single intraperitoneal injection of the inhibitor. Journal of Biochemical and Biophysical Methods 1982; 6: 341–349
  • Lowry O. H., Rosenbrough N. J., Farr A. L., Randall R. T. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 1951; 193: 265–275
  • Millkarek C., Price R. P., Penman S. Cordycepin effect on the biosynthesis of different RNA populations in mammalian cells. Cell 1974; 1: 1–10
  • Munro H. N., Fleck A. Recent developments in the nucleic acids measurements in biological material. Analyst 1966; 91: 78–88
  • Munroe S. H., Pederson T. On the sensitivity of hnRNP particles from the mammalian cultured cells to the digestion by ribonucleases of different types. Journal of Molecular Biology 1981; 147: 437–449
  • Murthy M. R. V. The kinetics of labelling of mRNA and rRNA in rat liver and brain tissues by a single intraperitoneal injection of radioactively labelled L-amino acids. Biochemica et Biophysica Acta 1968; 166: 115–123
  • Van Ness J., Maxwell I. H., Hahn W. E. The kinetic complexicity of poly(A)-containing and poly(A)-lacking populations of total polysomal mRNA in HeLa cells. Cell 1979; 18: 1341–1350
  • Ohlsson R. I., Van Eekelen C., Philipson L. Protein-RNA interactions in the hnRNP particles isolated from rat liver nuclei. A significance of the nuclei-spesific proteins. Nucleic Acids Research 1982; 10: 3053–3068
  • Pelham H. R. B., Jackson R. J. The efficient mRNA-dependent translation for reticulocyte lysate. European Journal of Biochemistry 1976; 67: 247–256
  • Perry R. P. mRNA processing in eucaryotic cells. Journal of cell Biology 1981; 91: 28–38
  • Petri R., Dimmock N. J. An improved method for a two-dimensional analysis of a complex mixtures of polypeptide chains isolated form the virus-infected mammalian cells. Journal of General Virology 1982; 57: 185–196
  • Sheiness D., Puckett L., Darnell J. E. mRNA Poly(A) segment shortening in HeLa cells treated with actinomycin D and emethine. Proceedings of the National Academy of Sciences of the USA 1975; 72: 1077–1081
  • Sieliwanowicz B. The fate of hnRNAs and cytoplasmic polysomal and non-polysomal RNAs after the complete blocking of intranuclear polyadenylation process by cordycepin in pigeon liver and spleen cells. Acta Biochimica Polonica 1985; 32: 239–245
  • Sippel A. E., Hynes N., Groner B., Schutz G. Isolation and an in vitro testing of highly purified and native nuclei from mouse embryonic tissues with a special microscopic control for their integrity. European Journal of Biochemistry 1977; 77: 141–151
  • Spieth J., Whitely A. H. The effect of cordycepin on protein synthesis in Arthemia salina embryos during the full duration of embryonic development. Development Biology 1980; 79: 95–106
  • Stanley H. F., Fink G. Synthesis of specific brain proteins is influenced by testosterone at mRNA level in the neonatal rat. Brain Research 1986; 370: 223–231
  • Tarantul V. Z., Gazaryan G. K. The biological significance of mRNA poly(A)-segments in eucaryotic cells: an overview. Advances in biological Chemistry of the USSR 1985; 22: 26–62, (in Russian and English)
  • Winkler E. Biostatistical approach to the investigation of protein turnover in animal cells. Acta Biologica et Medica Germanica 1984; 40: 227–255, (in German)
  • Zeevi M., Nevins J. R., Darnell J. E. Messenger RNA formation in the presence of cordycepin and cycloheximide in cultured 3T3 cells. Molecular and Cellular Biology 1982; 2: 517–525
  • Zieve G., Penman S. Heterogenous nuclear RNA and RNP from different types of human cultured cells. Journal of Molecular Biology 1981; 145: 501–523
  • Zomzely C. E., Roberts S., Peache S. Isolation and characterization of the native translatable polysomes and polysomal messenger RNA from rat brain cortex. Proceedings of the National Academy of Sciences of the USA 1970; 67: 644–651

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.