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Original Article

Ultrastructural Alterations in the Liver of Rats Fed Photomirex (8-Monohydromirex)

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Pages 487-496 | Published online: 06 Jul 2009

References

  • Hallett D. J., Norstrom R. J., Onvjska F. I. Mass spectral confirmation and analysis by the Hall detector of mirex and photomirex in herring gulls from Lake Ontario. J. Agric. FoodChem. 1976; 24: 1189–1193
  • Gaines T. B., Kimbrouoh R. D. Oral toxicity of mirex in adult and suckling rats with notes on the ultrastructure of liver changes. Arch. Environ. Health 1970; 21: 7–14
  • Baker R. C.L., Coons B., Mailman R. B., Hodgson E. Induction of hepatic mixed function oxidases by the insecticide, mirex. Environ. Res. 1972; 5: 418–424
  • Davison K. L., Mellenhauer H. H., Younger R. L., Cox J. H. Mirex-induced hepatic changes in chickens, Japanese quail, and rats. Arch. Environ. Contam. Toxicol. 1976; 4: 469–482
  • Fulfs J., Abraham R., Drobeck B. Species differences in the hepatic response to mirex: Ultrastructural and histochemical studies. Ecoloxicol. Environ. Safety 1977; 1: 327–342
  • Kendall W. M. Light and electron microscopic observations of the acute sublethal hepatotoxic effects of mirex in the rat. Arch. Environ. Contam. Toxicol. 1979; 8: 25–41
  • Chu I., Villeneuve D. C, Secours V. The absorption, distribution and excretion of photomirex in the rat. Drug Metab. Dispos. 1979; 7: 24–27
  • Watson M. L. Staining of tissue sections for electron microscopy with heavy metals. J. Biophys. Biochem. Cytol. 1958; 4: 475–478
  • Reynolds E. S. The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. J. Cell Biol. 1963; 17: 202–212
  • Villeneuve D. C, Valli V. E., Chu I. Ninety-day toxicity of photomirex in male rat. Toxicology 1979; 12: 235–250
  • Greenawalt J. W., Rossi C. S., Lehninger A. L. Effect of active accumulation of calcium and phosphate ions on the structure of rat liver mitochondria. J. Cell Biol. 1964; 23: 21–38
  • Watrach A. M. Degeneration of mitochondria in lead poisoning. J. Ultrastruct. Res. 1964; 10: 177–181
  • Lehninger A. L. The Mitochondrion. Molecular Basis of Structure and Function. Benjamin, New York 1965; 16–40
  • Van Dam K., Nieuwenhuis F. J. R.M., Steins J. H. W.L. Permeability of the mitochondrial membrane for ions and the relation between ion permeation and energy. Mitochondria: Biogenesis and Bioencrgetics. Eighth Meeting, Federation of European Biochemical Societies, North-Holland, Amsterdam, 1972; 387
  • Ghadially F. N. Ultrastructural Pathology of the Cell. A Text and Atlas of Physiological and Pathological Alterations in Cell Fine Structure. Butterworths, London 1975; 101–185
  • Byard J. L., Koepke U. C, Abraham R. Biochemical changes in the liver of mice fed mirex. Toxicol. Appl. Pharmacol. 1975; 33: 70–77
  • Chesney C. F., Allen J. R. Oxidative phosphorylation and respiration by liver mitochondria from polychlorinated biphenyl-intoxicated rats. Biochem. Pharmacol. 1974; 23: 1577–1582
  • Settlemire C. T., Huston A. S., Jacobs L. S. Action of some insecticides on membranes of mouse liver mitochondria. Bull Environ. Contam. Toxicol. 1974; 11: 169–173
  • Allen J. R., Carstens L. A., Abrahamson L. J. Responses of rats exposed to poly-chlorinated biphenyls for fifty-two weeks. I. Comparison of tissue levels of PCB and biological changes. Arch. Environ. Contam. 1976; 4: 404–419
  • Kasza L., Weinberger M. A., Carter C. Acute, subacute, and residual effects of polychlorinated biphenyl (PCB) in rats. II. Pathology and electron microscopy of liver and serum enzyme study. J. Toxicol. Environ. Health 1976; 1: 689–703
  • Ortega P. Light and electron microscopy of dichlorodiphenyltrichloroethane (DDT) poisoning in the rat liver. Lab. Invest. 1966; 15: 657–679
  • Nishizumi M. Light and electron microscope study of chlorobiphenyl poisoning in mouse and monkey liver. Arch. Environ. Health 1970; 21: 620–632
  • Kimbrough R. D., Linder R. E., Gaines T. B. Morphological changes in livers of rats fed polychlorinated biphenyls: Light microscopy and ultrastructure. Arch. Environ. Health 1972; 25: 354–364
  • Norback D. H., Allen J. R. Chlorinated aromatic hydrocarbon induced modifications of the hepatic endoplasmic reticulum: Concentric membrane arrays. Environ. Health Perspect. 1972; 1: 137–143
  • Hansell M. M., Ecobichon D. J. Effects of chemically pure chlorobiphenyls on the morphology of rat liver. Toxicol. Appl. Pharmacol. 1974; 28: 418–427
  • Hinton D. E., Glaumann H., Trump B. F. Studies on the cellular toxicity of polychlorinated biphenyls (PCBs). I. Effect of PCBs on microsomal enzymes and on synthesis and turnover of microsomal and cytoplasmic lipids of rat liver–a morphological and biochemical study. Virch. Arch. (Cell Pathol.) 1978; 27: 279–306
  • Kohli K. K., Gupta B. N., Albro P. W. Biochemical effects of pure isomers of hexachlorobiphenyl: Fatty livers and cell structure. Chent. Biol. Interact. 1979; 25: 139–156
  • Sandberg P. O., Glaumann H. Studies on the cellular toxicity of polychlorinated biphenyls (PCBs). Partial block and alteration of intracellular migration of lipoprotein particles in rat liver. Exp. Mol. Pathol. 1980; 32: 1–22
  • Fowler B. A., Lucier G. W., Brown H. W., McDaniel O. S. Ultrastructural changes in rat liver cells following a single and oral dose of TCDD. Environ. Health Perspect. 1973; 5: 141–148
  • Remmer H., Merker H. J. Drug-induced changes in the liver endoplasmic reticulum: Association with drug-metabolizing enzymes. Science 1963; 142: 1657–1658
  • Jones A. L., Fawcett D. W. Hypertrophy of the agranular endoplasmic reticulum in hamster liver induced by pheno-barbital (with a review on the functions of this organelle in liver). J. Histochem. Cytochem. 1966; 14: 215–232
  • Schaffner F. Some unresolved ultra-structural problems encountered in the study of the liver and its diseases. The Liver and Its Diseases, F. Schaffner, S. Sherlock, S. M. Leevy. Intercontinental Medical Book Corporation, New York 1974; 7–18
  • Remmer H. Detoxification of drugs in the liver. Progress in Liver Diseases, H. Popper, F. Schaffner. Grune & Stratton, New York 1965; 116–133
  • Conney A. H. Pharmacological implications of microsomal enzyme induction. Pharmacol. Rev. 1967; 19: 317–366
  • Cardell R. R. Smooth endoplasmic reticulum in rat hepatocytes during glycogen deposition and depletion. Int. Rev. Cytol. 1977; 48: 221–279
  • Hutterer F., Schaffner F., Klion F. M., Popper H. Hypertrophic, hypoactive smooth endoplasmic reticulum: A sensitive indicator of hepatotoxicity exemplified by dieldrin. Science 1968; 161: 1017–1019
  • Hutterer F., Klion F. M., Wengraf A. Hepatocellular adaptation and injury: structural and biochemical changes following dieldrin and methyl butter yellow. Lab. Invest. 1969; 20: 455–464
  • Koller L. D., Zinkel J. G. Pathology of polychlorinated biphenyls in rabbits. Am. J. Pathol. 1973; 70: 363–378
  • Porter K. R., Brum C. An electron microscope study of the early effects of 3′-Me-DAB on rat liver cells. Cancer Res. 1959; 19: 997–1009
  • Le Marchand Y., Singh A., Assimacopoulos-Jeannet F., Orci L., Rouiller C., Jeanrenaud B. A role for the micro-tubular system in the release of very low density lipoproteins by perfused mouse livers. J. Biol. Chem. 1973; 248: 6862–6870
  • Orci L., Le Marchand Y., Singh A. Role of microtubules in lipoprotein secretion by the liver. Nature 1973; 224: 30–32
  • Singh A., Le Marchand Y., Orci L., Jeanrenaud B. Colchicine administration to mice: A metabolic and ultrastructural study. Eur. J. Clin. Invest. 1975; 5: 495–505
  • Stein O., Stein Y. Colchicine-induced inhibition of very low density lipoprotein release by rat liver in vivo. Biochem. Biophys. Acta 1973; 306: 142–147
  • Stein O., Singer L., Stein Y. Colchicine-induced inhibition of lipoprotein and protein secretion into the serum and lack of interference with secretion of biliary phospholipids and cholesterol by rat liver in vivo. J. Cell. Biol. 1974; 62: 90–103
  • Redman C. M., Banerjee D., Howell K., Palade G. E. Colchicine inhibition of plasma protein release from rat hepatocytes. Cell Biol. 1975; 66: 42–59

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