Acquired immunogenicity of DNA after modification with malondialdehyde in patients with alopecia areata

References

• Ito T. Recent advances in the pathogenesis of autoimmune hair loss disease alopecia areata. Clin Dev Immunol 2013; 2013:348–546.
   Google Scholar
• Alkhalifah A. Alopecia areata update. Dermatol Clin 2013;31:93–108.
   PubMed Web of Science ®Google Scholar
• Bertolini M, Gilhar A, Paus R. Alopecia areata as a model for T cell-dependent autoimmune diseases. Exp Dermatol 2012;21:477–9.
   Google Scholar
• Seetharam KA. Alopecia areata: an update. Indian J Dermatol Venereol Leprol 2013;79:563–75.
   PubMed Web of Science ®Google Scholar
• Thomas EA, Kadyan RS. Alopecia areata and autoimmunity: a clinical study. Indian J Dermatol 2008;53:70–4.
   PubMedGoogle Scholar
• Hordinsky M, Ericson M. Autoimmunity: alopecia areata. J Investig Dermatol Symp Proc 2004;9:73–8.
   PubMed Web of Science ®Google Scholar
• Gilhar A, Etzioni A, Paus R. Alopecia areata. N Engl J Med 2012;366:1515–25.
   PubMed Web of Science ®Google Scholar
• Wang E, McElwee KJ. Etiopathogenesis of alopecia areata: why do our patients get it?. Dermatol Ther 2011; 24:337–47.
   PubMed Web of Science ®Google Scholar
• Bernot KM, Coulombe PA, McGowan KM. Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle. J Invest Dermatol 2002;119:1137–49.
   PubMedGoogle Scholar
• Leung MC, Sutton CW, Fenton DA, Tobin DJ. Trichohyalin is a potential major autoantigen in human alopecia areata. J Proteome Res 2010;9:5153–63.
   PubMed Web of Science ®Google Scholar
• Tobin DJ. Characterization of hair follicle antigens targeted by the anti-hair follicle immune response. J Investig Dermatol Symp Proc 2003;8:176–81.
   PubMedGoogle Scholar
• Koury EL, Price VH. No cell-surface-reactive antibodies against cultured autologous melanocytes found in alopecia areata sera. J Invest Dermatol 1995;104:S24.
   Google Scholar
• Galbraith GMP, Miller D, Emerson DL. Western blot analysis of serum antibody reactivity with human melanoma cell antigens in alopecia areata and vitiligo. Clin Immunol Immunopathol 1988;48:317–24.
   PubMedGoogle Scholar
• Friedmann PS. Alopecia areata and auto-immunity. Br J Dermatol 1981;105:153–7.
   PubMed Web of Science ®Google Scholar
• Kurtev A, Iliev E. Thyroid autoimmunity in children and adolescents with alopecia areata. Int J Dermatol 2005;44: 457–61.
   PubMed Web of Science ®Google Scholar
• Yano S, Ihn H, Nakamura K, Okochi H, Tamaki K. Antinuclear and antithyroid antibodies in 68 Japanese patients with alopecia areata. Dermatology 1999;199:191.
   Google Scholar
• Kuwano Y, Fujimoto M, Watanabe R, Asashima N, Nakashima H, Ohno H, Yano S, Yazawa N, Okochi H, Tamaki K. Serum anti-Fcgamma receptor autoantibodies in patients with alopecia areata. Arch Dermatol Res 2007; 298:493–8.
   Google Scholar
• Kemp EH, Sandhu HK, Weetman AP, McDonagh AJ. Demonstration of autoantibodies against tyrosine hydroxylase in patients with alopecia areata. Br J Dermatol 2011;165:1236–43.
   Google Scholar
• Abdel Fattah NS, Ebrahim AA, El Okda ES. Lipid peroxidation/antioxidant activity in patients with alopecia areata. J Eur Acad Dermatol Venereol 2011;25:403–8.
   PubMed Web of Science ®Google Scholar
• Akar A, Arca E, Erbil H, Akay C, Sayal A, Gur AR. Antioxidant enzymes and lipid peroxidation in the scalp of patients with alopecia areata. J Dermatol Sci 2002;29: 85–90.
   PubMed Web of Science ®Google Scholar
• Al-Shobaili HA, Alzolibani AA, Al Robaee AA, Meki AR, Rasheed Z. Biochemical markers of oxidative and nitrosative stress in acne vulgaris: correlation with disease activity. J Clin Lab Anal 2013;27:45–52.
   Google Scholar
• Rasheed Z, Al-Shobaili HA, Al Robaee AA, Alzolibani AA, Wadi WI, Khan MI, Al-Hamed HA. Preferential recognition of peroxynitrite damaged thymidine-monophosphate by anti-DNA autoantibodies in systemic lupus erythematosus. Nucleosides Nucleotides Nucleic Acids 2012;31:736–51.
   PubMed Web of Science ®Google Scholar
• Michel F, Bonnefont-Rousselot D, Mas E, Drai J, Therond P. Biomarkers of lipid peroxidation: analytical aspects. Ann Biol Clin (Paris) 2008;66:605–20.
   PubMed Web of Science ®Google Scholar
• Luczaj W, Skrzydlewska E. DNA damage caused by lipid peroxidation products. Cell Mol Biol Lett 2003;8:391–413.
   PubMed Web of Science ®Google Scholar
• Liu Y, Xu G ,Sayre LM. Carnosine inhibits (E)-4-hydroxy-2-nonenal-induced protein cross-linking: structural characterization of carnosine-HNE adducts. Chem Res Toxicol 2003;16:1589–97.
   PubMed Web of Science ®Google Scholar
• Al Arfaj AS, Chowdhary AR, Khalil N, Ali R. Immunogenicity of singlet oxygen modified human DNA: implications for anti-DNA antibodies in systemic lupus erythematosus. Clin Immunol 2007;124:83–9.
   PubMed Web of Science ®Google Scholar
• Chaudhary AK, Reddy GR, Blair IA, Marnett LJ. Characterization of an N6-oxopropenyl-2ʹ-deoxyadenosine adduct in malondialdehyde-modified DNA using liquid chromatography/electrospray ionization tandem mass spectrometry. Carcinogenesis 1996;17:1167–70.
   Google Scholar
• Nair V, Tumer GA, Offerman RJ. Novel adducts from the modification of nucleic acid bases by malondialdehyde. J Am Chem Soc 1984;106:3370–1.
   Google Scholar
• Stone K, Uzieblo A, Mamett LJ. Studies of the reaction of malondialdehyde with cytosine nucleosides. Chem Res Toxicol 1990;3:467–72.
   PubMed Web of Science ®Google Scholar
• Goda Y, Mamett LJ. High-performance liquid chromatography with electrochemical detection for determination of the major malondialdehyde-guianine adduct. Chem Res Toxicol 1991;4:520–4.
   PubMedGoogle Scholar
• Koca R, Armutcu F, Altinyazar C, Gurel A. Evaluation of lipid peroxidation, oxidant/antioxidant status, and serum nitric oxide levels in alopecia areata. Med Sci Monit 2005; 11:CR296–9.
   Google Scholar
• Mistry N, Podmore I, Cooke M, Butler P, Griffiths H, Herbert K, Lunec J. Novel monoclonal antibody recognition of oxidative DNA damage adduct, deoxycytidine-glyoxal. Lab Invest 2003;83:241–50.
   PubMed Web of Science ®Google Scholar
• Olsen E, Hordinsky M, McDonald-Hull S, Price V, Roberts J, Shapiro J, Stenn K. Alopecia areata investigational assessment guidelines. National alopecia areata foundation. J Am Acad Dermatol 1999;40:242–6.
   PubMed Web of Science ®Google Scholar
• Rasheed Z. Hydroxyl radical damaged immunoglobulin G in patients with rheumatoid arthritis: biochemical and immunological studies. Clin Biochem 2008;41:663–9.
   PubMed Web of Science ®Google Scholar
• Goding JW. Use of staphylococcal Protein-A as immunological reagent. J Immunol Methods 1978;20:241–54.
   PubMed Web of Science ®Google Scholar
• Al-Shobaili HA, Al Robaee AA, Alzolibani AA, Rasheed Z. Antibodies against 4-hydroxy-2-nonenal modified epitopes recognized chromatin and its oxidized forms: role of chromatin, oxidized forms of chromatin and 4-hydroxy-2-nonenal modified epitopes in the etiopathogenesis of SLE. Dis Markers 2012;33:19–34.
   PubMed Web of Science ®Google Scholar
• Rasheed Z, Al-Shobaili HA, Alzolibani AA, Ismail Khan M, Tariq Ayub M, Khan MI, Rasheed N. Immunological functions of oxidized human immunoglobulin G in type 1diabetes mellitus: its potential role in diabetic smokers as a biomarker of elevated oxidative stress. Dis Markers 2011; 31:47–54.
   PubMed Web of Science ®Google Scholar
• Draper HH, Hadley M. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol 1990;186: 421–31.
   PubMed Web of Science ®Google Scholar
• McElwee KJ, Gilhar A, Tobin DJ, Ramot Y, Sundberg JP, Nakamura M, Bertolini M, Inui S, Tokura Y, King LE Jr, Duque-Estrada B, Tosti A, Keren A, Itami S, Shoenfeld Y, Zlotogorski A, Paus R. What causes alopecia areata?. Exp Dermatol 2013;22:609–26.
   PubMed Web of Science ®Google Scholar
• Gilhar A, Landau M, Assy B, Shalaginov R, Serafimovich S, Kalish RS. Mediation of alopecia areata by cooperation between CD4 + and CD8 + T lymphocytes: transfer tohuman scalp explants on Prkdc(SCID) mice. Arch Dermatol 2002; 138:916–22.
   PubMed Web of Science ®Google Scholar
• McElwee KJ, Freyschmidt-Paul P, Hoffmann R, Kissling S, Hummel S, Vitacolonna M, Zöller M. Transfer of CD8(+) cells induces localized hair loss whereas CD4(+)/CD25(−) cells promote systemic alopecia areata and CD4(+)/CD25(+) cells blockade disease onset in the C3H/HeJ mouse model. J Invest Dermatol 2005;124:947–57.
   PubMed Web of Science ®Google Scholar
• Carroll JM, McElwee KJ, E King L, Byrne MC, Sundberg JP. Gene array profiling and immunomodulation studies define a cell-mediated immune response underlying the pathogenesis of alopecia areata in a mouse model and humans. J Invest Dermatol 2002;119:392–402.
   PubMed Web of Science ®Google Scholar
• Tobin DJ, Hann SK, Song MS, Bystryn JC. Hair follicle structures targeted by antibodies in patients with alopecia areata. Arch Dermatol 1997;133:57–61.
   PubMedGoogle Scholar
• McElwee KJ, Pickett P, Oliver RF. The DEBR rat, alopecia areata and autoantibodies to the hair follicle. Br J Dermatol 1996;134:55–63.
   PubMed Web of Science ®Google Scholar
• Gilhar A, Pillar T, Assay B, David M. Failure of passive transfer of serum from patients with alopecia areata and alopecia universalis to inhibit hair growth in transplants of human scalp skin grafted on to nude mice. Br J Dermatol 1992;126:166–71.
   PubMedGoogle Scholar
• Ahn KJ, Choi EA, Kim J, Lee JH, Lee KH, Bang D, Cho SB. Increased retinol-binding protein (RBP) 4 and anti-RBP4 antibody in alopecia areata. Br J Dermatol 2011; 165:837–44.
   Google Scholar
• Okamoto M, Ogawa Y, Watanabe A, Sugiura K, Shimomura Y, Aoki N, Nagasaka T, Tomita Y, Muro Y. Autoantibodies to DFS70/LEDGF are increased in alopecia areata patients. J Autoimmun 2004;23:257–66.
   Google Scholar
• Scofield RH, Kurien BT, Ganick S, McClain MT, Pye Q, James JA, Schneider RI, Broyles RH, Bachmann M, Hensley K. Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading. Free RadicBiol Med 2005;38:719–28.
   PubMed Web of Science ®Google Scholar
• Sultana R, Perluigi M, Allan Butterfield D. Lipid peroxidation triggers neurodegeneration: a redox proteomics view into the Alzheimer disease brain. Free Radic Biol Med 2012; S0891–5849:1161–6.
   Google Scholar
• Janero DR. Malondialdehyde and thiobarbituric acid- reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Radic Biol Med 1999;9: 515–40.
   Google Scholar
• Riggins JN, Marnett LJ. Mutagenicity of the malondialdehydeoligomerization products 2-(3ʹ-oxo-1ʹ-propenyl)-malondialdehyde and 2,4-dihydroxymethylene-3-(2,2, dimethoxy-ethyl) glutaraldehyde in Salmonella. Mutat Res 2001; 497:153–7.
   Google Scholar
• Niedernhofer LJ, Daniels JS, Rouzer CA, Greene RE, Marnett LJ. Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells. J Biol Chem 2003;278: 31426–33.
   PubMed Web of Science ®Google Scholar
• Fanelli SL, Castro JA. Carbon tetrachloride promoted malondialdehyde formation in liver microsomal and nuclear preparations from Sprague Dawley or Osborne Mendel male rats. Res Commun Chem Pathol Pharmacol 1993; 82:233–6.
   Google Scholar
• Marnett LJ. Oxy radicals, lipid peroxidation and DNA damage. Toxicology 2002;181–2:219–2.
   Google Scholar
• Zhang Y, Chen SY, Hsu T, Santella RM. Immunohistochemical detection of malondialdehyde-DNA adducts in human oral mucosa cells. Carcinogenesis 2002;23:207–11.
   PubMed Web of Science ®Google Scholar