Advanced search
Publication Cover
Scandinavian Journal of Clinical and Laboratory Investigation Volume 44, 1984 - Issue 1
Submit an article Journal homepage
36
Views
56
CrossRef citations to date
0
Altmetric
Original Article

Reference values for CSF-IgM, CSF-IgM/S-IgM ratio and IgM index, and its application to patients with multiple sclerosis and aseptic meningoencephalitis

P. Forsberg Department of Infectious Diseases, Karolinska Institutet, Huddinge Hospital, Stockholm, Sweden
,
A. Henriksson Department of Neurology, Karolinska Institutet, Huddinge Hospital, Stockholm, Sweden
,
H. Link Department of Neurology, Karolinska Institutet, Huddinge Hospital, Stockholm, Sweden
&
S. Öhman Clinical Chemistry, University Hospital, Linköping
Pages 7-12 | Received 08 Apr 1983, Accepted 25 Aug 1983, Published online: 08 Jul 2009

References

  • Diem K. Documenta Geigy. Scientific Tables6th edn. Basle 1962
  • Engvall E., Perlman P. Enzyme-linked immunosorbent assay (ELISA). Quantitative assay of immunoglobulin G. Immunochemistry. Pergamon Press. 1971; 8: 871
  • Forsberg P., Kam-Hansen S. Immunoglobulin-producing cells in blood and cerebrospinal fluid during the course of aseptic meningoencephalitis. Scand. J. Immunol. 1983; 17: 531
  • Frydén A., Link H. Predominance of oligoclonal IgG type lambda in CSF in aseptic meningitis. Archs. Neurol. 1979; 36: 478
  • Frydén A., Link H., Norrby E. Cerebrospinal fluid and serum immunoglobulins and antibody titers in mumps meningitis and aseptic meningitis of other etiology. Infect. Immun. 1978; 21: 852
  • Henriksson A., Kam-Hansen S., Anderson R. Immunoglobulin-producing cells in CSF and blood from patients with multiple sclerosis and other inflammatory neurological diseases enumerated by Protein A plaque assay. J. Neuroimmunol. 1981; 1: 299
  • Hische E. A. H., Van der Helm H. J., Out T. Estimation of IgM in cerebrospinal fluid by fluoroimmunoassay. Clinica chim. Acta 1979; 97: 93
  • Keir G., Walker R. W. H., Thompson E. J. Oligoclonal immunoglobulin M in cerebrospinal fluid from multiple sclerosis patients. J. Neurol. Sci. 1982; 57: 281
  • Kobatake K., Shinohara Y., Yoshimura S. Immunoglobulins in cerebrospinal fluid. Enzyme-Immunoassay. J. Neurol. Sci. 1980; 47: 273
  • Lamourex G., Jolicoeur R., Giard N., St-Hilaire M., Duplantis F. Cerebrospinal fluid proteins in multiple sclerosis. Neurology 1975; 25: 537
  • Larsson L., Ohman S. Serum calcium low activity. Some aspects on methodological differences and intraindividual variation. Clin. Biochem. 1979; 12: 138
  • Link H. Comparison of electrophoresis on agar gel and agarose in the evaluation of gamma-globulin abnormalities in cerebrospinal fluid and serum in multiple sclerosis. Clinica chim. Acta 1973; 46: 383
  • Link H. Immunoglobulin abnormalities in the Guillain- Barré syndrome. J. Neurol. Sci. 1973; 18: 11
  • Link H., Müller R. Immunoglobulins in multiple sclerosis and infections of the nervous system. Archs Neurol. 1971; 25: 326
  • Link H., Wahren B., Norrby E. Pleocytosis and immunoglobulin changes in cerebrospinal fluid and herpes virus serology in patients with Guillain-Barré syndrome. J. Clin. Microbiol. 1979; 9: 305
  • Mingioli E. S., Strober W., Tourtellotte W. W., Whitaker J. N., McFarlin D. E. Quantitation of IgG, IgA and IgM in the CSF by radioimmunoassay. Neurology 1978; 28: 991
  • Nerenberg S. T., Prasad R. Radioimmunoassays for Ig classes G, A, M, D, and E in spinal fluids: normal values of different age groups. J. Lab. Clin. Med. 1975; 86: 887
  • Nerenberg S. T., Prasad R., Rotham M. E. Cerebrospinal fluid IgG, IgA, IgM, IgD, and IgE levels in central nervous system disorders. Neurology 1978; 28: 988
  • Oxelius V.-A., Rorsman H., Laurell A.-B. Immunoglobulins of cerebrospinal fluid in syphilis. Br. J. vener. Dis. 1969; 45: 121
  • Reed A. H., Henry R. J., Mason W. B. Influence of statistical method used on the resulting estimate of normal range. Clin. Chem. 1971; 17: 275
  • Schneck S. A., Claman H. N. CSF immunoglobulins in multiple sclerosis and other neurologic diseases. Archs Neurol. 1969; 20: 132
  • Sindic C. J. M., Cambiaso C. L., Depré A., Laterre E. C., Masson P. L. The concentration of IgM in the cerebrospinal fluid of neurological patients. J. Neurol. Sci. 1982; 55: 339
  • Sindic C. J. M., Chalon M. P., Cambiaso C. L., Collet-Cassart D., Masson P. L. Particle counting immunoassay (PACIA). Part 6 (The determination of rabbit IgG antibodies against myelin basic protein using IgM rheumatoid factor). Mol. Immunol. 1981b; 10: 293
  • Snedecor G. W., Cochran W. G. Statistical Methods6th edn. Ames, Iowa 1967
  • Pedersen Strandberg N., Kam-Hansen S., Link H., Mavra M. Specificity of immunoglobulins synthesized within the central nervous system in neurosyphilis. Acta pathol. microbiol. scand. ‘C’ 1982; 90: 97
  • Tibbling G., Link H., Öhman S. Principles of albumin and IgG analyses in neurological disorders. I. Establishment of reference values. Scand. J. clin. Lab. Invest. 1977; 31: 385
  • Voller A., Bidwell D. E., Bartlett A. Enzyme immunoassays in diagnostic medicine. Bull. Wld Hlth Org. 1976; 53: 55
  • Williams A. C., Mingioli E. S., McFarland H. F., Tourtellotte W. W., McFarlin D. E. Increased CSF IgM in multiple sclerosis. Neurology 1978; 28: 996

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.