Calcium clamp technique: Suppression of serum intact PTH by induced hypercalcaemia in normal man and primary hyperparathyroidism

References

• Habener J F, Rosenblatt M, Potts J T. Parathyroid hormone: biochemical aspects of biosynthesis, secretion, action and metabolism. Physiol Rev 1984; 64: 985–1053
   PubMed Web of Science ®Google Scholar
• Rutledge R, Stiegel M, Thomas C G, Wild R E. The relation of serum calcium and immunoparathyroid hormone levels to parathyroid size and weight in primary hyperparathyroidism. Surgery 1985; 98: 1107–12
   PubMed Web of Science ®Google Scholar
• Manning R M, Adami S, Papadoupoulos S E, Gleed J H, Hendy G N, Rosenblatt M, O'Riordan J LH. A carboxy-terminal specific assay for human parathyroid hormone. Clin Endocrinol 1981; 15: 439–49
   PubMed Web of Science ®Google Scholar
• Papapoulos S E, Manning R M, Hendy G N, Lewin I G, O'Riordan J LH. Studies of circulating parathyroid hormone in man using a homologous ammino-terminal specific immunoradiometric assay. Clin Endocrinol 1980; 13: 57–67
   PubMed Web of Science ®Google Scholar
• Mayer G P, Keaton J A, Hurst J G, Hahener J F. Effects of plasma calcium concentration on the relative proportion of hormone and carboxyl fragments in parathyroid venous blood. Endocrinology 1979; 104: 1778–84
   PubMed Web of Science ®Google Scholar
• D'Amour P, Labelle F, Lecavalier L, Plourde V, Harvey D. Influence of Ca concentration on circulating molecular forms of PTH in three species. Am J Physiol 1986; 251: E680–7
   PubMed Web of Science ®Google Scholar
• Fogh-Andersen N. Renal and hepatic extraction of carhoxyl-terminal immunorcactivc parathyrin in normal man. J Clin Chem Clin Biochem 1984; 22: 479–82
   PubMedGoogle Scholar
• Martin K J, Hruska K A, Lewis J, Anderson C, Slatopolsky E. The renal handling of parathyroid hormone. Role of peritubular uptake and glomerular filtration. J Clin Invest 1977; 60: 808–14
   PubMed Web of Science ®Google Scholar
• Segre G V, Perkins A S, Witters L A, Potts J T. Metabolism of parathyroid hormone by isolated rat Kupffer cells and hcpatocytes. J Clin Invest 1981; 67: 449–57
   PubMed Web of Science ®Google Scholar
• Segre G V, D'Armour P, Hultman A, Potts J T. Effects of hepatectomy nephrectomy and nephrectomiauremia on the metabolism of parathyroid hormone in the rat. J Clin Invest 1981; 67: 439–48
   PubMed Web of Science ®Google Scholar
• Nussbaum S R, Zahradnik R I, Lavigne J R, Brennan G L, Nozawa-Ung K, Kim L Y, Keutmann H T, Wang C-A, Potts J T, Segre G V. Highly sensitive two-site immunoradiometric assay of parathyrin and its clinical utility in evaluating patients with hyperealeemia. Clin Chem 1987; 33: 1364–7
   PubMed Web of Science ®Google Scholar
• Blind E, Schmidt-Gayk H, Scharia Flentje D, Fisher S, Göhring U, Hintzler W. Two-site assay of intact parathyroid hormone in the investigation of primary hyperparathyroidism and other disorders of calcium metabolism compared with a midregion assay. J Clin Endocrinol McTab 1988; 67: 353–60
   PubMed Web of Science ®Google Scholar
• Pietilä K, Möski P, Pasternack A, Mustonen J, Koivula T. Intact parathyroid hormone ionized calcium and calcium infusion test in the evaluation of hyperparathyroidism in chronic renal failure. Nephron 1987; 47: 284–9
   PubMed Web of Science ®Google Scholar
• Mazzuoli G, Minisola S, Scarnecchia L, Pacitti M T, Carnevalc V, Romagnoli E, Bigi F, Bianchi G. Two-site assay of intact parathyroid hormone in primary hyperparathyroidism: studies in basal conditions following adenoma removal and during calcium and EDTA infusion. Clin Chim Acta 1990; 190: 239–48
   PubMed Web of Science ®Google Scholar
• Brent G A, LeBoff M S, Seely E W, Conlin P R, Brown E M. Relationship between the concentration and rate of change of calcium and serum intact parathyroid hormone levels in normal humans. J Clin Endocrinol Metab 1988; 67: 944–50
   PubMed Web of Science ®Google Scholar
• Lips P, Netelenbos J C, Van Doom L, Hackeng W HL, Lips C JM. Stimulation of intact parathyroid hormone (PTH1–84) in normal subjects and hyperparathyroid patients. Clin Endocrinol 1991; 35: 35–40
   PubMed Web of Science ®Google Scholar
• Arnaud C D. Hormonal regulation of calcium homcostasis. Assay of Calcium Regulating Hormones, DD Bikle. Springer-Verlag, New York 1983; 1–19
   Google Scholar
• Tørring O, Sjöberg HE. A ionized calcium regulated calcium clamp technique in man. Scand J Clin Lab Invest 1983; 43: 101–4, Suppl 165
   Web of Science ®Google Scholar
• Tørring O, Sjöberg HE. A calcium clamp technique in man. Acta Physiol Scand 1983; 119: 387–92
   PubMedGoogle Scholar
• Thode J. Ionized calcium and cyclic AMP in plasma and urine. Biochemical evaluation in calcium metabolic disease. Thesis, University of Copenhagen, 1989. Scand J Clin Lab Invest 1990; 50: 1–45, (suppl 197)
   PubMed Web of Science ®Google Scholar
• Walton R J, Bijvoet O LM. Nomogram for derivation of renal threshold phosphate concentration. Lancet 1975; ii: 309–10
   Web of Science ®Google Scholar
• Nordin B EC, Fraser R. The effect of intravenous calcium on phosphate excretion. Clin Sci 1954; 13: 477–90
   PubMed Web of Science ®Google Scholar
• Peacock M, Robertson W G, Nordin B EC. Relation between serum and urinary calcium with particular reference to parathyroid activity. Lancet 1969; 384–6
   PubMed Web of Science ®Google Scholar
• Nordin B EC, Hodgkinson A, Peacock M. The measurement and the meaning of urinary calcium. Calcium, Phosphate and Magnesium Metabolism, BEC Nordin. Churchill-Livingstone, Edinburgh and London 1976; 293–321
   Google Scholar
• Stewart A F, Horst R, Deftos L J, Cadman E C, Lang R, Broadus A E. Biochemical evaluation of patients with cancer-associated hypercalcemia. Evidence for humoral and non-humeral groups. N Engl J Med 1980; 303: 1377–83
   PubMed Web of Science ®Google Scholar
• Transbøl I. Hypercalcaemia: endocrine and metabolic aspects. Thesis. University of Copenhagen. 1978
   Google Scholar
• Kubler N, Krause U, Wagner P K, Beyer J, Rothmund M. The role of intraglandular PTH degradation in the pathogenesis of primary hyperparathyroidism. Abstract no. 209. XIX European symposium on calcified tissues, Stockholm, 1986
   Google Scholar
• Curlcy I R, Wheeler M H, Aston J P, Brown R C, Weeks I, Woodhead J S. Studies in patients with hyperparathyroidism using a new two-site immunochemiluminometric assay for circulating intact (1–84) parathyroid hormone. Surgery 1987; 102: 926–31
   PubMed Web of Science ®Google Scholar