The incidence of Crohn’s disease and ulcerative colitis since 1995 in Danish children and adolescents <17 years – based on nationwide registry data

References

• Benchimol EI, Fortinsky KJ, Gozdyra P, et al. Epidemiology of pediatric inflammatory bowel disease: a systematic review of international trends. Inflamm Bowel Dis. 2011;17:423–439.
   PubMed Web of Science ®Google Scholar
• Day AS, Ledder O, Leach ST, et al. Crohn's and colitis in children and adolescents. World J Gastroenterol. 2012;18:5862–5869.
   PubMed Web of Science ®Google Scholar
• Jakobsen C, Paerregaard A, Munkholm P, et al. Pediatric inflammatory bowel disease: increasing incidence, decreasing surgery rate, and compromised nutritional status: a prospective population-based cohort study 2007-2009. Inflamm Bowel Dis. 2011;17:2541–2550.
   PubMed Web of Science ®Google Scholar
• Abraham BP, Mehta S, El-Serag HB. Natural history of pediatric-onset inflammatory bowel disease: a systematic review. J Clin Gastroenterol. 2012;46:581–589.
   PubMed Web of Science ®Google Scholar
• Schechter A, Griffiths C, Gana JC, et al. Early endoscopic, laboratory and clinical predictors of poor disease course in paediatric ulcerative colitis. Gut. 2015;64:580–588.
   PubMed Web of Science ®Google Scholar
• Van Limbergen J, Russell RK, Drummond HE, et al. Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease. Gastroenterology. 2008;135:1114–1122.
   PubMed Web of Science ®Google Scholar
• Herzog D, Fournier N, Buehr P, et al. Early-onset Crohn's disease is a risk factor for smaller final height. Eur J Gastroenterol Hepatol. 2014;26:1234–1239.
   PubMed Web of Science ®Google Scholar
• Ruemmele FM, Veres G, Kolho KL, et al. Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease. J Crohns Colitis. 2014;8:1179–1207.
   PubMed Web of Science ®Google Scholar
• Lynge E, Sandegaard JL, Rebolj M. The Danish National Patient Register. Scand J Public Health. 2011;39:30–33.
   PubMed Web of Science ®Google Scholar
• Andersen TF, Madsen M, Jorgensen J, et al. The Danish national hospital register. A valuable source of data for modern health sciences. Dan Med Bull. 1999;46:263–268.
   PubMed Web of Science ®Google Scholar
• Statistics Denmark. Statistiske efterretninger, Sociale forhold, sundhed og retsvæsen. [Statistical news, health, justice, 2011]. 2012:5.
   Google Scholar
• Pedersen CB. The Danish civil registration system. Scand J Public Health. 2011;39:22–25.
   PubMed Web of Science ®Google Scholar
• Schmidt M, Pedersen L, Sorensen HT. The Danish civil registration system as a tool in epidemiology. Eur J Epidemiol. 2014;29:541–549.
   PubMed Web of Science ®Google Scholar
• Levine A, Griffiths A, Markowitz J, et al. Pediatric modification of the montreal classification for inflammatory bowel disease: the Paris classification. Inflamm Bowel Dis. 2011;17:1314–1321.
   PubMed Web of Science ®Google Scholar
• Uhlig HH, Schwerd T, Koletzko S, et al. The diagnostic approach to monogenic very early onset inflammatory bowel disease. Gastroenterology. 2014;147:990–1007.e3.
   PubMed Web of Science ®Google Scholar
• Tiwari RC, Clegg LX, Zou Z. Efficient interval estimation for age-adjusted cancer rates. Stat Methods Med Res. 2006;15:547–569.
   PubMed Web of Science ®Google Scholar
• Norgard BM, Nielsen J, Fonager K, et al. The incidence of ulcerative colitis (1995–2011) and Crohn's disease (1995–2012) – based on nationwide Danish registry data. J Crohns Colitis. 2014;8:1274–1280.
   PubMed Web of Science ®Google Scholar
• Jakobsen C, Wewer V, Urne F, et al. Incidence of ulcerative colitis and Crohn's disease in Danish children: still rising or levelling out? J Crohns Colitis. 2008;2:152–157.
   PubMed Web of Science ®Google Scholar
• Jakobsen C, Paerregaard A, Munkholm P, et al. Paediatric inflammatory bowel disease during a 44-year period in Copenhagen county: occurrence, course and prognosis – a population-based study from the Danish Crohn Colitis database. Eur J Gastroenterol Hepatol. 2009;21:1291–1301.
   PubMed Web of Science ®Google Scholar
• Sjoberg D, Holmstrom T, Larsson M, et al. Incidence and clinical course of Crohn's disease during the first year – results from the IBD Cohort of the Uppsala region (ICURE) of Sweden 2005–2009. J Crohns Colitis. 2014;8:215–222.
   PubMed Web of Science ®Google Scholar
• Martin-de-Carpi J, Rodriguez A, Ramos E, et al. Increasing incidence of pediatric inflammatory bowel disease in Spain (1996-2009): the SPIRIT Registry. Inflamm Bowel Dis. 2013;19:73–80.
   PubMed Web of Science ®Google Scholar
• Lehtinen P, Ashorn M, Iltanen S, et al. Incidence trends of pediatric inflammatory bowel disease in Finland, 1987–2003, a nationwide study. Inflamm Bowel Dis. 2011;17:1778–1783.
   PubMed Web of Science ®Google Scholar
• Lovasz BD, Lakatos L, Horvath A, et al. Incidence rates and disease course of paediatric inflammatory bowel diseases in western Hungary between 1977 and 2011. Dig Liver Dis. 2014;46:405–411.
   PubMedGoogle Scholar
• Pozler O, Maly J, Bonova O, et al. Incidence of Crohn disease in the Czech Republic in the years 1990 to 2001 and assessment of pediatric population with inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2006;42:186–189.
   PubMed Web of Science ®Google Scholar
• Chouraki V, Savoye G, Dauchet L, et al. The changing pattern of Crohn's disease incidence in northern France: a continuing increase in the 10- to 19-year-old age bracket (1988–2007). Aliment Pharmacol Ther. 2011;33:1133–1142.
   PubMed Web of Science ®Google Scholar
• Grieci T, Butter A. The incidence of inflammatory bowel disease in the pediatric population of Southwestern Ontario. J Pediatr Surg. 2009;44:977–980.
   PubMed Web of Science ®Google Scholar
• El-Matary W, Moroz SP, Bernstein CN. Inflammatory bowel disease in children of Manitoba: 30 years' experience of a tertiary center. J Pediatr Gastroenterol Nutr. 2014;59:763–766.
   PubMed Web of Science ®Google Scholar
• Adamiak T, Walkiewicz-Jedrzejczak D, Fish D, et al. Incidence, clinical characteristics, and natural history of pediatric IBD in Wisconsin: a population-based epidemiological study. Inflamm Bowel Dis. 2013;19:1218–1223.
   PubMed Web of Science ®Google Scholar
• Orel R, Kamhi T, Vidmar G, et al. Epidemiology of pediatric chronic inflammatory bowel disease in central and western Slovenia, 1994–2005. J Pediatr Gastroenterol Nutr. 2009;48:579–586.
   PubMed Web of Science ®Google Scholar
• Savoye G, Salleron J, Gower-Rousseau C, et al. Clinical predictors at diagnosis of disabling pediatric Crohn's disease. Inflamm Bowel Dis. 2012;18:2072–2078.
   PubMed Web of Science ®Google Scholar
• Schildkraut V, Alex G, Cameron DJ, et al. Sixty-year study of incidence of childhood ulcerative colitis finds eleven-fold increase beginning in 1990s. Inflamm Bowel Dis. 2013;19:1–6.
   PubMed Web of Science ®Google Scholar
• Malmborg P, Grahnquist L, Lindholm J, et al. Increasing incidence of paediatric inflammatory bowel disease in northern Stockholm county, 2002-2007. J Pediatr Gastroenterol Nutr. 2013;57:29–34.
   PubMed Web of Science ®Google Scholar
• Ekbom A. The epidemiology of IBD: a lot of data but little knowledge. How shall we proceed? Inflamm Bowel Dis. 2004;10:S32–S34.
   PubMed Web of Science ®Google Scholar
• Fonager K, Sorensen HT, Rasmussen SN, et al. Assessment of the diagnoses of Crohn's disease and ulcerative colitis in a Danish hospital information system. Scand J Gastroenterol. 1996;31:154–159.
   PubMed Web of Science ®Google Scholar