13
Views
15
CrossRef citations to date
0
Altmetric
Original Article

Abnormal Intestinal Permeability Pattern in Colonic Crohn's Disease: Absorption of Low Molecular Weight Polyethylene Glycols after Oral or Colonic Load

, , &
Pages 571-576 | Received 04 Aug 1988, Accepted 13 Jan 1989, Published online: 08 Jul 2009

References

  • Gebbers J O, Otto HF. Alterations of the intestinal mucosal block in ulcerative colitis and Crohn's disease. Immunological and ultrastructural findings, and considerations of the pathogenesis. Klin Paediatr 1985; 197: 341–348
  • Hodgson H JF, Potter B J, Jewell DP. Immune complexes in ulcerative colitis and Crohn's disease. CIin Exp Immunol 1977; 29: 187–196
  • Walker W A, Isselbacher KJ. Uptake and transport of macromolecules by the intestine. Possible role in clinical disorders. Gastroenterology 1974; 67: 531–550
  • Ward M. The pathogenesis of Crohn's disease. Lancet 1977; 2: 903–905
  • Magnusson K-E, Sundqvist T, Sjödahl R, Tagesson C. Altered intestinal permeability to low-molecular weight polyethyleneglycols (PEG 400) in patients with Crohn's disease. Acta Chir Scand 1983; 149: 323–327
  • Heuman R, Sjödahl R, Tagesson C. Passage of molecules through the wall of the gastrointestinal tract. Intestinal permeability to polyethyleneglycol 1000 in patients with Crohn's disease. Acta Chir Scand 1982; 148: 281–284
  • Olaison G, Sjödahl R, Tagesson C. Decreased permeability to different-sized polyethyleneglycols in ileocaecal Crohn's disease. A sign of jejunal abnormality. Acta Chir Scand 1987; 153: 373–377
  • Olaison G, Leandersson P, Sjödahl R, Tagesson C. Intestinal permeability to polyethyleneglycols 600 in Crohn's disease. Peroperative determination in a defined segment of the small intestine. Gut 1988; 29: 196–199
  • Morson BC. Histopathology of Crohn's disease. Proc R SOC Med 1968; 61: 79–81
  • Lockhart-Mummery H E, Morson BC. Crohn's disease (regional enteritis) of the large intestine and its distinction from ulcerative colitis. Gut 1960; 1: 87–105
  • Pera A, Bellando P, Caldera D, Ponfi V, Astegiano M, Barletti C, David E, et al. Colonoscopy in inflammatory bowel disease. Diagnostic accuracy and proposal of an endoscopic score. Gastroenterology 1987; 92: 181–185
  • Tagesson C, Anderson P A, Anderson T, Bolin T, Källberg M, Sjödahl R. Passage of molecules through the wall of the gastrointestinal tract. Measurement of intestinal permeability to polyethylene glycols in the 634–1338-dalton range (PEG 1000). Scand J Gastroenterol 1983; 18: 481–486
  • Menzies IS. Transmucosal passage of inert molecules in health and disease. Intestinal absorption and secretion, E Skadhauge, K Heintze. MTP Press Ltd, Lancaster 1983; 527–547
  • Maxton D G, Bjarnasson I, Reynolds A P, Catt S D, Peters T J, Menzies IS. Lactulose 51Cr-labelled ethylenediaminetetra-acetate, L-rhamnose and polyethyleneglycol 500 as probe markers for assessment in vivo of human intestinal permeability. Clin Sci 1986; 71: 71–80
  • Dunne W T, Cooke W T, Allan RN. Enzymatic and morphometric evidence for Crohn's disease as a diffuse lesion of the gastrointestinal tract. Gut 1977; 18: 290–294
  • Marin M L, Greenstein A J, Geller S A, Gordon R E, Aufses AH. A freeze fracture study of Crohn's disease of the terminal ileum: changes in epithelial tight junction organization. Am J Gastroenterol 1983; 78: 537–547
  • Rickert R R, Carter HW. The 'early' ulcerative lesion of Crohn's disease: correlative light- and scanning electron-microscopic studies. J Clin Gastroenterol 1980; 2: 11–19
  • O'Morain C A, Abelov C A, Cheruu L R, Fleischner GM. Chromium 51-ethylenediaminetetraacetate: a useful test in the assessment of inflammatory bowel disease. J Lab Clin Med 1986; 108: 430–435
  • Homan W P, Dineen P. Comparison of the results of resection, by-pass and by-pass with exclusion for ileocecal Crohn's disease. Ann Surg 1978; 187: 530–535
  • Muller J M, Keller H W, Erasmi H, Pichlmaier H. Total parenteral nutrition as the sole therapy in Crohn's disease—a prospective study. Br J Surg 1983; 70: 40–43
  • Fisher R B, Parsons DS. The gradient of mucosal surface area in the small intestine of the rat. J Anat 1950; 84: 272–282
  • Chadwick V S, Phillips S F, Hofmann AF. Measurements of intestinal permeability using low molecular weight polyethyleneglycols (PEG 400). II. Application to normal and abnormal permeability states in man and animals. Gastroenterology 1977; 73: 247–251

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.