6
Views
5
CrossRef citations to date
0
Altmetric
Original Article

Dose-Dependent Effects of Glycine, Alanine, and Glucose on Hepatic Bile Secretion, Oxygen Consumption, and Hemodynamics

&
Pages 1265-1273 | Received 23 Jan 1990, Accepted 06 Jun 1990, Published online: 08 Jul 2009

References

  • Mathisen Ø, Omland E. Amino acid- and glucose-induced cholestasis before and during secretin stimulation. Scand J Gastroenterol 1989; 24: 851–858
  • Hayashi N, Kasahara A, Meren H, et al. Delivery and use of oxygen in the hepatic tissue assessed by organ-reflectance spectrophotometry. Adv Exp Med Biol 1986; 200: 113–117
  • Van Dyke R W, Gollan J L, Scharschmidt B F. Oxygen consumption by rat liver: effects of taurocholate and sulfobromophthalein transport, glucagon and cation substitution. Am J Physiol 1983; 244: G523–G531
  • Scholtholt J. Das Verhalten der Durchblutung der Leber bei Steigung des Sauerstoffverbrauches der Leber. Pfluegers Arch 1970; 318: 202–216
  • Gusberg R J, Gump F E, Kinney J M. The demands of hyperalimentation on splanchnic blood flow and oxygen consumption. Surg Forum 1974; 25: 56–58
  • Tavoloni N, Reed J, Boyer J L. Hemodynamic effects on determinants of bile secretion in isolated rat liver. Am J Physiol 1978; 234: E584–E592
  • Matsumura T, Sato N, Kawano S, Hijoko T, Eguchi H, Kamada T. Effect of hepatic blood oxygenation on bile secretion in rats. Adv Exp Med Biol 1988; 222: 585–589
  • Mathisen O, Schistad O, Strand M. Role of osmosis in biliary NaCI secretion and bile formation. Scand J Gastroenterol 1985; 20: 971–977
  • Refsum H E, Sveinsson S L. Spectrophotometric determination of hemoglobin oxygen saturation in hemolyzed whole blood. Scand J Clin Invest 1956; 8: 67–70
  • Bartels H, Harms H. Sauerstoffdissoziationskurven des Blutes von Saugetieren. Pfluegers Arch Ges Physiol 1959; 268: 334–351
  • Legare D J, Lautt W W. Hepatic venous resistance site in the dog: localization and validation of intrahepatic pressure measurements. Can J Physiol Pharmacol 1987; 65: 352–359
  • Fausa O, Skalhegg B A. Quantitative determination of bile acids and their conjugates using thin layer chromatography and a purified 3-alpha-hydro-cysteroid dehydrogenase. Scand J Gastroenterol 1974; 9: 249–254
  • Snedecor G W, Cochran W G. Statistical methods. 6th ed. State University Press, Ames, Iowa 1967; 128–171
  • Graham M F, Tavill A S. Halpin TC, Louis LN. Inhibition of bile flow in the isolated perfused rat liver by a synthetic parenteral aminoacid mixture: associated net aminoacid fluxes. Hepatology 1984; 4: 69–73
  • Belli D G, Fournier A L, Lepage G, et al. Total parenteral nutrition-associated cholestasis in rats: Comparison of different aminoacid mixtures. JPEN 1987; 11: 67–73
  • Krarup N, Larsen J A. The effect of glucagon on hepatosplanchnic hemodynamics, functional capacity and metabolism of the liver in cats. Acta Physiol Scand 1974; 91: 42–52
  • Lucke J N, Hall G M. A technique for measuring hepatic blood flow and oxygen consumption in the anaesthetized pig. Res Vet Sci 1978; 25: 393–394
  • Hems R, Ross B D, Berry M N, Krebs H A. Gluco-neogenesis in the perfused rat liver. Biochem J 1966; 101: 284–292
  • Perez-Sala D, Parilla R, Ayosos S M. Key role of l-alanine in the control of hepatic protein synthesis. Biochem J 1987; 241: 491–498
  • Kristensen Lø. Associations between transport of alanine and cations across cell membranes in rat hepatocytes. Am J Physiol 1986; 251: G575–G584
  • Miiller M J, Möring J, Seitz H J. Regulation of hepatic glucose output by glucose in vivo. Metabolism 1988; 37: 55–60
  • Newsholme E A, Challiss R AJ, Crabtree B. Substrate cycles: their role in improving sensitivity in metabolic control. Trend Biochem Sci 1984; 9: 277–280
  • Reuben A. Bile formation: sites and mechanisms. Hepatology 1984; 4: 15S–24S
  • Sejersted O M, Mathisen Ø, Kiil F. Oxygen requirement of renal Na-K-ATPase-dependent sodium reabsorption. Am J Physiol 1977; 232: F152–F158
  • Mathisen Ø, Monclair T, Kiil F. Oxygen requirement of bicarbonate-dependent sodium reabsorption in the dog kidney. Am J Physiol 1980; 238: F175–F180
  • Johannesen J, Lie M, Kiil F. Renal energy metabolism and sodium reabsorption after 2,4-dinitro-phenol administration. Am J Physiol 1977; 233: F207–F212
  • Mathisen Ø, Omland E, Flatmark A. Cholestasis after cyclosporin A and glucose. Transplant Proc 1988; 20(suppl 1)160–161
  • Kock N G, Hahnloser P, Roding G B, et al. Interaction between portal venous and hepatic arterial blood flow: an experimental study in the dog. Surgery 1972; 72: 414–419
  • Lautt W W, Greenway C V. Conceptual review of the hepatic vascular bed. Hepatology 1987; 7: 952–963
  • Johannesen J, Lie M, Kiil F. Effect of glycine and glucagon on glomerular filtration and metabolic rate. Am J Physiol 1977; 233: F61–F66
  • Ferrannini E, DeFronzo R A, Gusberg R, et al. Splanchnic amino acid and glucose metabolism during aminoacid infusion in dogs. Diabetes 1988; 37: 237–245
  • Premen A J. Importance of the liver during gluc-agon-mediated increases in renal hemodynamics. Am J Physiol 1985; 249: F319–F322
  • Ohnhaus E E, Noelpp V B, Ramos M R. Liver blood flow and enzyme induction in man. Hepato-gastroenterology 1985; 32: 61–64
  • Bottje W G, Hassan A S, Holmes K R. Evidence for the association between total hepatic blood flow and hepatic glutathione content. Biochem Pharmacol 1986; 35: 1629–1632
  • Mathisen Ø, Raeder M. Role of sodium, bicarbonate and plasma osmolality in biliary secretion. Scand J Gastroenterol 1983; 18: 825–832
  • Mathisen Ø, Rseder M. Mechanism of hepatic bicarbonate secretion and bile acid independent bile secretion. Eur J Clin Invest 1983; 13: 193–200
  • Lowe P J, Miyai K, Steinbuch J H, Hardison W G. Hormonal regulation of hepatocyte tight junctional permeability. Am J Physiol 1988; 255: G454–G461

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.