The Influence of Pregnancy and Contraceptive Steroids on the Biliary Tract and Its Reference to Cholesterol Gallstone Formation

References

• Boston Collaborative Drug Surveillancc Program. Oral contraceptive venous thrornhocmbolic disease. surgically confirmed gallbladdcr discase, and breast tumors. Lancet 1973; 1: 1399–3404
   PubMedGoogle Scholar
• Friedman G D, Kannel W B, Danbert T R. Thc epidemiology of gallbladder disease. Observations iii the Framingham study. J Cron Dis 1966; 19: 277–292
   Google Scholar
• Nilsson S. Gallbladder disease and sex hormon A statistical study. Acta Chir Scand 1960; 132: 27–279
   Google Scholar
• The Coronary Drug Research Group. Gallbladder disease as a side effect of drugs influencing lipid metabolism. N Engl J Med 1977; 296: 1185–1190
   PubMedGoogle Scholar
• Scragg R, McMichael A J, Seamark R F. Oral contraceptives, pregnancy and endogenous estrogen in gallbladder disease—a case control study. Br Med J 1984; 288: 1795–1799
   PubMed Web of Science ®Google Scholar
• Leissner K H, Wedel H, Scherstén T. Comparison between the use of oral contraceptives and the incidence of surgically confirmed gallbladder disease. Scand J Gastroenterol 1977; 12: 893–896
   PubMed Web of Science ®Google Scholar
• Royal College of General Practitioners. Diseases of the respiratory and digestive systems. Oral contraceptives and health. Pitham Medical, London 1974; 5759
   Google Scholar
• Boston Collaborative Drug Surveillance Program. Surgically confirmed gallbladder disease, venous thromboembolism, and breast tumors in relation to postmenopausal estrogen therapy. N Engl J Med 1974; 290: 15–18
   PubMed Web of Science ®Google Scholar
• Kern F, Jr, Eriksson H, Curstedt T, Sjovall J. Effect of ethinylestradiol on biliary excretion of bile acids, and cholesterol in the bile fistula rats. J Lip Res 1977; 18: 623–634
   PubMedGoogle Scholar
• Yousef J M, Fisher M M. Influence of pregnancy on bile acid pool of rats. Clin Res 1973; 21: 1036
   Google Scholar
• McSherry K C, Dietrick J E, May P S, et al. Biliary lipid metabolism in the pregnant baboon. Ann Surg 1971; 173: 569–577
   PubMed Web of Science ®Google Scholar
• Morrissey K, Panveliwalla D, MacSherry C, Dietrick J, Niemana W, Gupta G. Effects of contraceptive steroids and pregnancy on bile composition and kinetics in the baboon. J Surg Res 1977; 22: 598–604
   PubMedGoogle Scholar
• Reyes H, Kern F, Jr. Effect of pregnancy on bile flow and biliary lipids in the hamster. Gastroenterology 1979; 76: 144–150
   PubMedGoogle Scholar
• Rådberg G, Friman S, Samsioe G, Svanvik J. Enterohepatic bile acid circulation in the pregnant cat. Acta Physiol Scand 1988; 133: 19–24
   PubMedGoogle Scholar
• Holzbach R T, Marsh M E, Hallberg C M. The effect of pregnancy on lipid composition of guinea pig gallbladder bile. Gastroenterology 1971; 60: 288–293
   PubMedGoogle Scholar
• Martin D E, Wolf R C, Meyer R K. The effects of pregnancy on biliary lipids in Rhesus monkeys. Proc Soc Exp Biol Med 1972; 139: 115–117
   PubMedGoogle Scholar
• Riegel C, Ravdin I S, Morrison P J, Potter M J. Studies on gallbladder function. X. I. The composition of gallbladder bile in pregnancy. JAMA 1935; 105: 1343–1344
   Google Scholar
• Potter M J. Observations of the gallbladder and bile during pregnancy at term. JAMA 1936; 106: 1070–1074
   Google Scholar
• Large A M, Johnston C G, Katsuki T, Fachnie H J. Gallstones in pregnancy; the composition of gallbladder bile in pregnant women at term. Am J Med Sci 1960; 91: 713–720
   Google Scholar
• Lindstedt S. The turnover of cholic acid in man. Acta Physiol Scand 1957; 40: 1–9
   PubMedGoogle Scholar
• Kern F, Everson G T, DeMark B, et al. Biliary lipids bile acid, and gallbladder function in the human female. Effects of pregnancy and ovulatory cycle. J Clin Invest 1981; 68: 1229–1242
   PubMed Web of Science ®Google Scholar
• Laatikainen T J, Lethonen P J, Hesso A E. Fetal sulfated and nonsulfated bile acids in intrahpeatic cholestasis of pregnancy. J Lab Clin Med 1978; 92: 185–193
   PubMed Web of Science ®Google Scholar
• Sjövall K, Sjövall J. Serum bile acid levels in pregnancy with pruritus. Clin Chim Acta 1966; 13: 207–211
   PubMed Web of Science ®Google Scholar
• Horness P S. Gastroentero-pancreatic hormones in pregnancy. Scand J Gastroenterol 1984; 19: 451–456
   PubMedGoogle Scholar
• Linden A, Eriksson M, Carlquist M. Uvnäs-Moberg K. Plasma levels of gastrin, somatostatin and chole-cystokinin immunoreactivity during pregnancy and lactation in dogs. Gastroenterology 1987; 92: 578–584
   PubMed Web of Science ®Google Scholar
• Rädberg G, Rehfeld J F, Cantor P, et al. Chole-cystokinin secretion in pregnancy. Scand J Gastroenterol 1987; 22: 687–690
   PubMed Web of Science ®Google Scholar
• Gerdes M, Boyden E. The rate of emptying of the human gallbladder in pregnancy. Surg Gynecol Obstet 1938; 66: 145–156
   Google Scholar
• Levyn L, Beck E, Aaron A. Cholecystography in the late month of pregnancy. Radiology 1928; 11: 48–52
   Google Scholar
• Braverman D Z, Johnson M L, Kern F, Jr. Effects of pregnancy and contraceptive steroids on gallbladder function. N Engl J Med 1980; 302: 362–364
   PubMed Web of Science ®Google Scholar
• Everson G T, McKinley C, Lawson M, Johnson M, Kern F, Jr. Gallbladder function in the human female: effects of the ovulatory cycle, pregnancy and contraceptive steroids. Gastroenterology 1982; 82: 711–719
   PubMed Web of Science ®Google Scholar
• Rädberg G, Asztely M, Cantor P, Rehfeld J F. Järnfeldt-Samsioe A, Svanvik J. Gastric and gallbladder emptying in relation to the secretion of cholecystokinin after a meal in late pregnancy. Digestion 1989; 42: 174–180
   PubMed Web of Science ®Google Scholar
• Ryan J P. Calcium and gallbladder smooth muscle contraction in the guinea pig: effect of pregnancy. Gastroenterology 1985; 89: 1279–1285
   PubMed Web of Science ®Google Scholar
• Rådberg G, Svanvik J. Influence of pregnancy, oophorectomy and contraceptive steroids on gallbladder concentrating function and hepatic bile flow in the cat. Gut 1986; 27: 10–14
   PubMedGoogle Scholar
• Pellecchia D, McCallion M, Ryan J P. Influence of progesterone in vivo on antral and gallbladder motility in vitro. Fed Proc 1981; 40: 577A
   Google Scholar
• Ryan J P, Bhojwani A, Wang M B. Effect of pregnancy on gastric motility in vivo and in vitro in the guinea pig. Gastroenterology 1987; 93: 29–34
   PubMedGoogle Scholar
• Parry E, Shields R, Thurnbull A C. Transit time in che small intestine in pregnancy. J Obstet Gynecol Br Commun 1970; 77: 900–901
   PubMedGoogle Scholar
• Wald A, Van Thiel D H, Hoechstetter L, et al. Effect of pregnancy on gastrointestinal transit. Dig Dis Sci 1982; 11: 1015–1018
   Google Scholar
• Schade R R, Pelekanos M J, Tauxe W N, Van Thiel D H. Gastric emptying during pregnancy ‘Abstract’. Gastroenterology 1984; 86: 1124
   Google Scholar
• Davison J S, Davison M C, Hay D M. Gastric emptying time in late pregnancy and labour. J Obstet Gynecol Br Commun 1970; 77: 37–43
   PubMedGoogle Scholar
• Clark J M, Seager S J. Gastric emptying following premedication with glycopyrolate or atropine. Br J Anaesth 1983; 55: 1195–1199
   PubMedGoogle Scholar
• Nakayama I, Van der Linden W. Stratification of bile in gallstone formation. Surg Gyn Obstet 1975; 141: 587–590
   PubMedGoogle Scholar
• Tera H. Stratification of human gallbladder bile in vivo. Acta Chir Scand 1960, suppl 256
   Google Scholar
• Thureborn E. Human hepatic bile ‘Thesis’. Acta Chir Scand 1962, suppl 303
   Google Scholar
• Ihasz M, Graffith C. Gallstones after vagotomy. Am J Surg 1981; 141: 48
   PubMedGoogle Scholar
• Björk S, Jansson R, Svanvik J. The concentrating function of the feline gallbladder after truncal vagotomy. Acta Chir Scand 1984; 150: 393–396
   PubMedGoogle Scholar
• O'Malley K, Stevensson I H, Crooks J. Impairment of human drug metabolism by oral contraceptive steroids. Clin Pharmacol Ther 1972; 13: 552–557
   PubMed Web of Science ®Google Scholar
• Dickey R P, Stone S C. Progestional potency of oral contraceptives. Surg Obstet Gynecol 1976; 47: 106–112
   Google Scholar
• Forker E L. The effect of estrogen on bile formation in the rat. J Clin Invest 1969; 48: 654–663
   PubMed Web of Science ®Google Scholar
• Porter L E, Elm L S, Van Thiel D H. Hepatic estrogen receptot in human liver disease. Gastro-enterology 1987; 92: 734–735
   Google Scholar
• Singletary B K, Van Thiel D H, Eagon P K. Estrogen and progcstcronc receptors in human gallbladder. Hepatology 1986; 6: 574–578
   PubMedGoogle Scholar
• Anderson A, James O, MacDonald H, Snowball S, Taylor W. The effect of ethinylestradiol on biliary lipid composition in young men. Eur J Clin Invest 1980; 10: 77–78
   PubMed Web of Science ®Google Scholar
• Bonorris G G, Coync M J, Chung A, Schoenfield L S. Mechanim of estrogen-induced saturated bile in the hamster. J Lab Clin Med 1977; 90: 963–970
   PubMedGoogle Scholar
• Davis R A, Kcrn F, Jr. Effects of ethinylcstradiol and phenobarbital on bile acid synthesis and biliary bile acid and cholestcrol extraction. Gastroen-terology 1976; 70: 1130–1135
   PubMed Web of Science ®Google Scholar
• DelPino V L, Carter J, La Russo M F. Ethinylestradiol inhibits bile flow and biliary protein secretion but stimulates release of lysosomal cnzymcs into bile. Gastroenterology 1976; 76: 1118
   Google Scholar
• Javitt N B, Panvelivalla D, Morissey K. Ethinylestradiol: long term effects on bile acid metabolism in the baboon. Clin Res 1975; 23: 439A
   Google Scholar
• Keeffe E B, Scarschmidt B F, Blankenship N M, Ockner R K. Studies of relationships among bile Anw, liver plasma membrane NA K-ATP-ase and membrane microviscosity in the rat. J Clin Invest 1979; 64: 1590–1598
   PubMed Web of Science ®Google Scholar
• Kern F, Jr, Eriksson H, Cursted T, Sjovall J. Effect of ethinylestradiol on biliary extraction of bile acids, phosphatidylcholines. and cholesterol in the bile fistula rat. J Lip Res 1977; 18: 623–634
   PubMedGoogle Scholar
• Lynn J L, Williams L, O'Brien J, Egdahl R H. Effects of estrogen upon bile. Implications with respect to gallstone formation. Ann Surg 1973; 178: 514–521
   PubMed Web of Science ®Google Scholar
• Davis R A, Kern F, Showalter R, Sutherland E, Sinensky M, Simon F. Alterations of hepatic Na-K-ATP-ase and bile flow by estrogen: Effects of liver surface membrane lipid structure and function. Proc Natl Acad Sci 1978; 75: 4130–4134
   PubMed Web of Science ®Google Scholar
• Nilsson S, Schersth T. Importance of bile acids for phospholipid secretion into human hepatic bile. Gastroenterology 1969; 57: 525–532
   PubMed Web of Science ®Google Scholar
• Northfield T C, Hoffman A F. Biliary output during threc meals and an overnight fast. Gut 1975; 16: 1–17
   PubMed Web of Science ®Google Scholar
• Lindblad L, Scherstén T. Jnfluence of cholic and chcnodcoxycholic acid on canalicular bile flow in miin. Gastroenterology 1976; 70: 1121–1124
   PubMedGoogle Scholar
• Scherstén T, Nilsson S, Cahlin E, Filipsson M, Brodin-Persson G. Relationship between the biliary excretion of bile acids and the excretion of water. lecithin, and cholesterol in man. Eur J Clin Invest 1971; 1: 242–247
   PubMed Web of Science ®Google Scholar
• Davis R A, Showalter R, Kern F. Reversal by Triton W. R. 1339 of cthinylestradiol induced hepatic cholesterol esterification. Biochem J 1978; 74: 4551
   Google Scholar
• Bennion L J, Ginsberg R I, Gamic M B, Bennet P H. Effects of oral contraceptives on the gallbladder bile of normal women. N Engl J Med 1976; 294: 189–192
   PubMed Web of Science ®Google Scholar
• Bennion L J, Mott D M, Howard B V. Oral contraceptives raise the cholesterol saturation of bile by increased biliary cholesterol secretion. Metabolism 1980; 29: 18–22
   PubMedGoogle Scholar
• Down R H L, Whitting M S, Watts J M, Jones W. Effect of synthetic estrogens and progestagens in contraceptives on bile lipid composition. Gut 1983; 24: 253–259
   PubMed Web of Science ®Google Scholar
• Hirst B H, Lund P K, Reed J C, Sanders D J, Shaw B, Taylor W. Effects of combined estrogen-progestin preparation on gastric acid and pepsin secretion, serum gastrin concentration and biliary secretion of bile acids, phospholipids and cholesterol in the cat. Br J Pharmacol 1979; 65: 87–95
   PubMedGoogle Scholar
• Pertsemlidis D, Panveliwalla D, Ahrens E H. Effects of clofibrate and of an estrogen-progestin combination on fasting biliary lipids and cholic acid kinetics in man. Gastroenterology 1974; 66: 565–573
   PubMed Web of Science ®Google Scholar
• White C M, Howat J M T, Shofield P F. Lithogen bile: a study in women taking oral contraceptives. Rr J Surg 1976; 63: 664
   Google Scholar
• Ridberg G, Friman S, Samsioe G, Svanvik J. Direct measurements of enterohepatic circulation of bile acids in the cat. Influence of contraceptive steroids and oophorectomy. Scand J Gastroenterol 1987; 22: 827–832
   PubMedGoogle Scholar
• Iqubal S, Mills C, Elias E. Biliary permeability during ethinylestradiol-induced cholestasis studied by segment retrograde intrabiliary injections in rats. Hepatology 1985; 1: 211–219
   Google Scholar
• Nervi F O, DelPosso R, Covarrubias C F, Ronco B O. The effect of progesterone on the regulatory mechanisms of biliary cholesterol secretion in the rat. Hepatology 1983; 3: 360–367
   PubMedGoogle Scholar
• Imamoglu K, Wangensteen S L, Root H P. Production of gallstones by prolonged administration of progesterone and estradiol in rabbits. Surg Forum 1959; 10: 246–249
   Google Scholar
• Carey M C. The enterohepatic circulation. The liver: biology and pathobiology, I Arias, H Popper, D Scachter, D A Shafritz. Raven Press, New York 1982
   Google Scholar