Advanced search
Publication Cover
Scandinavian Journal of Gastroenterology Volume 26, 1991 - Issue 2
Submit an article Journal homepage
41
Views
39
CrossRef citations to date
0
Altmetric
Original Article

Neurophysiologic Studies of Patients with Crohn's Disease on Long-Term Treatment with Metronidazole

D. Ståhlberg Depts. of Medicine and Clinical Neurophysiology, Karolinska Institute at Huddinge University Hospital, Huddinge, Sweden; Depts. of Infectious Diseases and Clinical Neurophysiology, University Hospital, Lund, Sweden
,
F. Bárány Depts. of Medicine and Clinical Neurophysiology, Karolinska Institute at Huddinge University Hospital, Huddinge, Sweden; Depts. of Infectious Diseases and Clinical Neurophysiology, University Hospital, Lund, Sweden
,
K. Einarsson Depts. of Medicine and Clinical Neurophysiology, Karolinska Institute at Huddinge University Hospital, Huddinge, Sweden; Depts. of Infectious Diseases and Clinical Neurophysiology, University Hospital, Lund, Sweden
,
B. Ursing Depts. of Medicine and Clinical Neurophysiology, Karolinska Institute at Huddinge University Hospital, Huddinge, Sweden; Depts. of Infectious Diseases and Clinical Neurophysiology, University Hospital, Lund, Sweden
,
D. Elmqvist Depts. of Medicine and Clinical Neurophysiology, Karolinska Institute at Huddinge University Hospital, Huddinge, Sweden; Depts. of Infectious Diseases and Clinical Neurophysiology, University Hospital, Lund, Sweden
&
A. Persson Depts. of Medicine and Clinical Neurophysiology, Karolinska Institute at Huddinge University Hospital, Huddinge, Sweden; Depts. of Infectious Diseases and Clinical Neurophysiology, University Hospital, Lund, Sweden
Pages 219-224 | Received 18 Jun 1990, Accepted 08 Aug 1990, Published online: 08 Jul 2009

References

  • Ursing B, Kamme C. Metronidazole for Crohn's disease. Lancet 1975; 1: 775–777
  • Rosen A, Ursing B, Aim T, et al. A comparative study of metronidazole and sulfasalazine for active Crohn's disease: The Cooperative Crohn's Disease Study in Sweden. I. Design and methodological considerations. Gastroenterology 1982; 83: 541–549
  • Ursing B, Aim T, Bárány F, et al. A comparative study of metronidazole and sulfasalazine for active Crohn's disease: The Cooperative Crohn's Disease Study in Sweden. II. Results. Gastroenterology 1982; 83: 550–562
  • Bernstein L H, Frank M S, Brandt L J, Boley S J. Healing of perineal Crohn's disease with metronidazole. Gastroenterology 1980; 79: 357–365
  • Brandt L J, Bernstein L H, Boley S J, Frank M S. Metronidazole therapy for perineal Crohn's disease: a follow-up study. Gastroenterology 1982; 83: 383–387
  • Coxon A, Pallis C A. Metronidazole neuropathy. Neurol Neurosurg Psychiatry 1976; 39: 403–405
  • Bradley W G, Karlsson I J, Rassol C G. Metronidazole neuropathy. Br Med J 1977; 3: 610–611
  • Karlsson I J, Hamlyn A N. Metronidazole neuropathy. Br Med J 1977; 3: 832
  • Said G, Goasguen J, Laverdant C. Polynévrites au cours des traitements prolongés par le metronidazole. Rev Neurol (Paris) 1978; 134: 515–521
  • You B, Grilliat J P. La neuropathic au metronidazole. Nouv Presse Med 1981; 10: 708
  • Noring L. Metronidazolinducerad polyneuropati. Lakartidningen 1982; 79: 546
  • Duffy L F, Daum F, Fisher S E, et al. Peripheral neuropathy in Crohn's disease patients treated with metronidazole. Gastroenterology 1985; 88: 681–684
  • Hillbom M, Wennberg A. Prognosis of alcoholic peripheral neuropathy. J Neurol Neurosurg Psychiatry 1984; 47: 699–703
  • Goldberg J M, Lindblom U. Standardized method of determining vibratory perception thresholds for diagnosis and screening in neurological investigation. J Neurol Neurosurg Psychiatry 1979; 42: 793–803
  • Fruhstorfer H, Lindblom U, Schmidt W C. Method for quantitative estimation of thermal thresholds in patients. J Neurol Neurosurg Psychiatry 1976; 39: 1071–1075
  • Persson A, Solders G. R-R variations, a test of autonomic dysfunction. Acta Neurol Scand 1983; 67: 285–293
  • Peripheral nerve disorders. Butterworths international medical reviews: Neurology, A K Asbury, R W Gilliat. Butterworths, Boston 1984; Vol. 4: 97
  • Läsionen peripherer Nerven, M Mumenthaler, Schliack. Georg Thieme, Stuttgart 1982; 93
  • Argov Z, Mastaglia F L. Drug-induced peripheral neuropathies. Br Med J 1979; 1: 663–666
  • Rankin G B, Watts H D, Melnyk C S, Kelley M L. National cooperative Crohn's disease study: extraintestinal manifestations and perianal complications. Gastroenterology 1979; 77: 914–920
  • Gendelman S, Present D, Janowitz H D. Neurological complications of inflammatory bowel disease. Gastroenterology 1982; 82: 1065
  • Cohen M G, Webb J. Brachial neuritis with colitic arthritis. Ann Intern Med 1987; 106: 780–781
  • Humbert P, Monnier G, Billerey C, Birgen C, Dupont J L. Polyneuropathy: an unusual extraintestinal manifestation of Crohn's disease. Acta Neurol Scand 1989; 80: 301–306
  • Urtasun R C, Rabin H R, Partington J. Human pharmacokinetics and toxicity of high-dose metronidazole administered orally and intravenously. Surgery 1983; 93: 145–148
  • Graham D G. Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol Pharmacol 1978; 14: 633–643
  • Graham D G, Tiffany S M, Bell W R, Gutknecht W F. Autooxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds towards C1300 neuroblastoma cells in vitro. Mol Pharmacol 1978; 14: 644–653
  • Donaldson J, LaBella F S, Gesser D. Enhanced autooxidation of dopamine as a possible basis of manganese neurotoxicity. Neurotoxicity 1980; 2: 53–64
  • Rao D N R, Mason R P. Generation of nitro radical anions of some 5-nitrofurans, 2-and 5-nitroimidazoles by norepinephrine, dopamine, and serotonin. J Biol Chem 1987; 262: 11731–11736
  • Rose G P, Dewar A J, Stratford I J. A biochemical neurotoxicity study relating the neurotoxic potential of metronidazole and nitrofurantoin with misonidazole. Int J Radial Oncol Biol Phys 1982; 8: 781–785
  • Eifel P J, Brown D M, Lee W W, Brown J M. Misonidazole neurotoxicity in mice decreased by administration with pyridoxine. Int J Radial Oncol Biol Phys 1983; 9: 1513–1519

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.