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Scandinavian Journal of Gastroenterology Volume 27, 1992 - Issue 5
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Original Article

Stimulatory Effect of Epidermal Growth Factor on Liver Regeneration after Partial Hepatectomy in Rats

T. N. Rasmussen Dept. of Surgery C and Dept. of Medicine A, Rigshospitalet, University of Copenhagen, Denmark; Dept. of Medical Physiology C, The Panum Institute, University of Copenhagen, Denmark
,
P. E. JøSrgensen Dept. of Surgery C and Dept. of Medicine A, Rigshospitalet, University of Copenhagen, Denmark; Dept. of Medical Physiology C, The Panum Institute, University of Copenhagen, Denmark
,
T. Almdal Dept. of Surgery C and Dept. of Medicine A, Rigshospitalet, University of Copenhagen, Denmark; Dept. of Medical Physiology C, The Panum Institute, University of Copenhagen, Denmark
,
P. Kirkegaard Dept. of Surgery C and Dept. of Medicine A, Rigshospitalet, University of Copenhagen, Denmark; Dept. of Medical Physiology C, The Panum Institute, University of Copenhagen, Denmark
&
P. Skov Olsen Dept. of Surgery C and Dept. of Medicine A, Rigshospitalet, University of Copenhagen, Denmark; Dept. of Medical Physiology C, The Panum Institute, University of Copenhagen, Denmark
Pages 372-374 | Received 11 Jun 1991, Accepted 16 Nov 1991, Published online: 08 Jul 2009

References

  • Marti U, Burwen S J, Jones A L. Biological effects of epidermal growth factor, with special emphasis on the gastrointestinal tract and liver: an update. Hepatology 1989; 9: 126–38
  • Skov Olsen P. Role of epidermal growth factor in gastroduodenal mucosal protection. J Clin Gastroenterol 1988; S146–S151, Suppl 1
  • Oka Y, Orth D. Human plasma epidermal growth factor/β-urogastrone is associated with blood platelets. J Clin Invest 1983; 72: 249–59
  • Savage A P, Chatterjee V K, Gregory H, Bloom S R. Epidermal growth factor in blood. Regul Peptides 1986; 16: 199–206
  • Yeh Y C, Scheving L A, Tsai T H, Scheving L E. Circadian stage-dependent effects of epidermal growth factor on deoxyribonucleic acid synthesis in ten different organs of the adult male mouse. Endocrinology 1981; 109: 644–51
  • Leffert H L, Koch K S, Moran T, Rubalcava B. Hormonal control of rat liver regeneration. Gastroenterology 1979; 76: 1470–82
  • Francavilla A, Ove P, Polimeno L, et al. Different response to epidermal growth factor of hepatocytes in cultures isolated from male or female rat liver. Gastroenterology 1987; 93: 597–605
  • Francavilla A, Ove P, Polimeno L, Sciascia C, Coetzee M L, Starzl T E. Epidermal growth factor and proliferation in rat hepatocytes in primary culture isolated at different times after partial hepatectomy. Cancer Res 1986; 46: 1318–23
  • Bucher N LR, Palel U, Cohen S. Hormonal factors and liver growth. Advances in enzyme regulation, G Weber. Pergamon Press, London 1978; Vol. 16: 205–13
  • Skov Olsen P, Boesby S, Kirkegaard P, et al. Influence of epidermal growth factor on liver regeneration after partial hepatectomy in rats. Hepatology 1988; 8: 992–6
  • Opleta K, O'Loughlin E V, Shaffer E A, Hayden J, Hollenberg M, Gall D G. Effect of epidermal growth factor on growth and postnatal development of the rabbit liver. Am J Physiol 1987; 253: G622–6
  • Higgins G M, Anderson R M. Experimental pathology of the liver. Arch Pathol 1931; 12: 186–202
  • Monro A N, Fleck A. The determination of nucleic acids. Methods Biochem Anal 1966; 14: 113–76
  • Bucher N LR, Swaffield M N. The rate of incorporation of labeled thymidine into the deoxyribonucleic acid of regenerating rat liver in relation to the amount of liver excised. Cancer Res 1964; 24: 1611–25
  • Sand T-E, Brønstad G, Digernes V, et al. Quantitative aspects of the effects of insulin, epidermal growth factor and dex-amethasone on DNA synthesis in cultured rat hepatocytes. Acta Endocrinol 1985; 109: 369–77
  • Moore G PM, Panaretto B A, Robertson D. Effects of epidermal growth factor on hair growth in the mouse. J Endocr 1981; 88: 293–9
  • Cohen S. Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. J Biol Chem 1962; 237: 1555–62
  • Earp H S, O'Keefe E J. Epidermal growth factor receptor number decreases during rat liver regeneration. J Clin Invest 1981; 67: 1580–3
  • Sawada N. Hepatocytes from old rats retain responsiveness of c-myc expression to EGF in primary culture but do not enter S phase. Exp Cell Res 1989; 181: 584–8
  • Hollenberg M D. Epidermal growth factor-urogastrone, a polypeptide acquiring hormonal status. Vitam Horm 1979; 37: 69–110
  • Bucher N LR, Patel U, Cohen S. Hormonal factors concerned with liver regeneration. In: Hepatotrophic factors. Ciba Found Sym 1978, 55: 95–110, (new series)
  • Poulsen S S, Nexø E, Skov Olsen P, Hess J, Kirkegaard P. Immunohistochemical localization of epidermal growth factor in rat and man. Histochemistry 1986; 85: 389–94
  • Raper S E, Burwen S J, Barker M E, Jones A L. Translocation of epidermal growth factor to the hepatocyte nucleus during rat liver regeneration. Gastroenterology 1987; 92: 1243–50
  • Cornell R P. Gut-derived endotoxin elicits hepatotrophic factor secretion for liver regeneration. Am J Physiol 1985; 249: R551–62
  • Wollenberg G K, Harris L, Farber E, Hayes M A. Inverse relationship between epidermal growth factor induced proliferation and expression of high affinity surface epidermal growth factor receptors in rat hepatocytes. Lab Invest 1989; 60: 254–9

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