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Scandinavian Journal of Gastroenterology Volume 27, 1992 - Issue 2
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Original Article

The Effects of Omeprazole on Interdigestive Motility and Early Postprandial Levels of Gastrin and Secretin

L. Rasmussen Depts. of Surgical and Medical Gastroenterology, Odense University Hospital, Copenhagen, Denmark; Dept. of Clinical Physiology, Division of Diagnostic Nuclear Medicine, Odense University Hospital, Copenhagen, Denmark; Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, Denmark
,
E. Øster-Jørgensen Depts. of Surgical and Medical Gastroenterology, Odense University Hospital, Copenhagen, Denmark; Dept. of Clinical Physiology, Division of Diagnostic Nuclear Medicine, Odense University Hospital, Copenhagen, Denmark; Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, Denmark
,
N. Qvist Depts. of Surgical and Medical Gastroenterology, Odense University Hospital, Copenhagen, Denmark; Dept. of Clinical Physiology, Division of Diagnostic Nuclear Medicine, Odense University Hospital, Copenhagen, Denmark; Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, Denmark
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C. P. Hovendal Depts. of Surgical and Medical Gastroenterology, Odense University Hospital, Copenhagen, Denmark; Dept. of Clinical Physiology, Division of Diagnostic Nuclear Medicine, Odense University Hospital, Copenhagen, Denmark; Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, Denmark
,
K. Kraglund Depts. of Surgical and Medical Gastroenterology, Odense University Hospital, Copenhagen, Denmark; Dept. of Clinical Physiology, Division of Diagnostic Nuclear Medicine, Odense University Hospital, Copenhagen, Denmark; Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, Denmark
,
O. Olsen Depts. of Surgical and Medical Gastroenterology, Odense University Hospital, Copenhagen, Denmark; Dept. of Clinical Physiology, Division of Diagnostic Nuclear Medicine, Odense University Hospital, Copenhagen, Denmark; Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, Denmark
,
O. B. Schaffalitzky de Muckadell Depts. of Surgical and Medical Gastroenterology, Odense University Hospital, Copenhagen, Denmark; Dept. of Clinical Physiology, Division of Diagnostic Nuclear Medicine, Odense University Hospital, Copenhagen, Denmark; Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, Denmark
,
J. Rehfeld Depts. of Surgical and Medical Gastroenterology, Odense University Hospital, Copenhagen, Denmark; Dept. of Clinical Physiology, Division of Diagnostic Nuclear Medicine, Odense University Hospital, Copenhagen, Denmark; Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, Denmark
&
S. A. Pedersen Depts. of Surgical and Medical Gastroenterology, Odense University Hospital, Copenhagen, Denmark; Dept. of Clinical Physiology, Division of Diagnostic Nuclear Medicine, Odense University Hospital, Copenhagen, Denmark; Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, Denmark
 show all
Pages 119-123 | Received 26 Jun 1991, Accepted 16 Sep 1991, Published online: 05 Aug 2009

References

  • Vantrappen G R, Peeters T L, Janssens J. The secretory component of the interdigestive migrating motor complex in humans. Scand J Gastroenterol 1979; 14: 663–667
  • Keane F B, DiMagno E P, Malagelada J R. Duodenogastric reflux in humans: its relationship to fasting antroduodenal motility and gastric, pancreatic, and biliary secretion. Gastroenterology 1981; 81: 726–731
  • Schaffalitzky de Muckadell O B, Fahrenkrug J. Radioimmunoassay of secretin in plasma. Scand J Clin Lab Invest 1977; 37: 155–162
  • Jacobsen O, Bardram L, Rehfeld J F. The requirement for gastrin measurements. Scand J Clin Lab Invest 1986; 46: 423–426
  • Pedersen S A, Kraglund K, Vinter-Jensen L. The effects of omeprazole on gastro-oesophageal sphincter pressure, intragastric pH, and the migrating motor complex in fasting healthy subjects. Scand J Gastroenterol 1987; 22: 725–730
  • Peters M N, Feldman M, Walsh J H, Richardson C T. Effect of gastric alkalinization on serum gastrin concentration in humans. Gastroenterology 1983; 85: 35–39
  • Greenberg G R, McCloy R F, Baron J H, Bryant M G, Bloom S R. Gastric acid regulates the release of plasma secretin in man. Eur J Clin Invest 1982; 12: 361–372
  • Schaffalitzky de Muckadell O B, Fahrenkrug J. Secretion pattern of secretin in man: regulation by gastric acid. Gut 1978; 19: 812–818
  • Festen H P M, Thijs J C, Lamers C B H W, et al. Effect of oral omeprazole on serum gastrin and serum pepsinogen I levels. Gastroenterology 1984; 87: 1030–1034
  • You C H, Chey W Y. Secretin is an enterogastrone in humans. Dig Dis Sci 1987; 32: 466–471
  • Simoens C, Woussen-Colle M C, De Graef J. Effect of cimetidine, ranitidine and omeprazole on post-prandial gastrin and somatostatin release in conscious dogs. Regul Peptides 1988; 22: 285–293
  • Schaffalitzky de Muckadell O B, Olsen O, Cantor P, Magid E. Concentration of secretin and CCK in plasma and pancreaticobiliary secretion in response to intraduodenal acid and fat. Pancreas 1986; 1: 536–543

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