Comparison of Polysucrose 15000, ⁵¹Cr-labelled Ethylenediaminetetraacetic Acid, and ¹⁴C-Mannitol as Markers of Intestinal Permeability in Man

References

• Menzies IS. Transmucosal passage of inert molecules in health and disease. Falk symposium 36. Intestinal absorption and secretion., E Skadhauge, K Heintz. MTP Press Ltd, Lancaster 1984; 527–43
   Google Scholar
• Bjarnason I, Peters T J, Levi AJ. Intestinal permeability: clinical correlates. Dig Dis 1986; 483–92
   Google Scholar
• Maxton D G, Bjarnason I, Reynolds A P, Catt S D, Peters T J, Menzies IS. Lactulose, 51Cr-labelled ethylenediaminetetra-acetate, L-rhamnose and polyethyleneglycol 400 as probe markers for assessment in vivo of human intestinal permeability. Clin Sci 1986; 71: 71–80
   PubMed Web of Science ®Google Scholar
• Marcial M A, Carlson S L, Madara JL. Partitioning of paracellular conductance along the ileal crypt-villous axis: a hypothesis based on structural analysis with detailed consideration of tight junction structure-function relationships. J Membrane Biol 1984; 80: 59–70
   PubMed Web of Science ®Google Scholar
• Hollander D. The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn's disease. Scand J Gastroenterol 1992; 27: 721–6
   PubMed Web of Science ®Google Scholar
• Chadwick V S, Phillips S F, Hofmann AF. Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). I. Chemical analysis and biological properties of PEG 400. Gastroenterology 1977; 73: 241–6
   PubMed Web of Science ®Google Scholar
• Chadwick V S, Phillips S F, Hofmann AF. Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Application to normal and abnormal permeability states in man and animals. Gastroenterology 1977; 73: 247–51
   PubMed Web of Science ®Google Scholar
• Ukabam S O, Cooper BT. Small intestinal permeability to mannitd lactulose, and polyethylene glycol 400 in celiac disease. Dig Dis Sci 1984; 29: 809–16
   PubMed Web of Science ®Google Scholar
• Iqbal T H, Lewis K O, Cooper BT. Diffusion of polyethylene glycol-400 across lipid barriers in vitro. Clin Sci 1993; 85: 111–5
   Web of Science ®Google Scholar
• Ma T Y, Hollander D, Krugliak P, Katz K. Peg 400, a hydrophilic molecule probe for measuring intestinal permeability. Gastroenterology 1990; 98: 39–46
   PubMed Web of Science ®Google Scholar
• Bjarnas I, Williams P, So A, Zanelli G D, Levi A J, Gumpel J M, et al. Intestinal permeability and inflammation in rheumatoid arthritis: effects of non-steroidal anti-inflammatory drugs. Lancet 1984; 2: 1171–4
   PubMed Web of Science ®Google Scholar
• Bjarnason I, Peters T J, Wise RJ. The leaky gut of alcoholism: possible route of entry for toxic compounds. Lancet 1984; 1: 179–82
   PubMed Web of Science ®Google Scholar
• Öman H, Åkerblom E, Richter W, Johansson S GO. Chemical and physiological properties of polysucrose, a new marker of intestinal permeability to macromolecules. Int Arch Allergy Appl Immunol 1992; 98: 220–6
   Google Scholar
• Öman H, Henriksson K, Blomquist L, Johansson S GO. Increased intestinal permeability to a synthetic polysucrose in NSAID-treated patients. Eur J Gastroenterol Hepatol 1992; 4: 235–40
   Web of Science ®Google Scholar
• Blomquist L, Öman H, Henriksson K, Johansson S GO. Increased absorption of polysucrose, a marker of intestinal paracellular permeability, in Crohn's disease. Eur J Gastroenterol Hepatol 1993; 5: 913–7
   Web of Science ®Google Scholar
• Bjarnason I, Zanelli G, Smith T, Prouse P, Williams P, Smethurst P, et al. Nonsteroidal antiinflammatory drug-induced intestinal inflammation in humans. Gastroenterology 1987; 93: 480–9
   PubMed Web of Science ®Google Scholar
• La Brooy S J, Male P-J, Beavis A K, Misiewicz JJ. Assessment of the reproducibility of the lactulose H2 breath test as a measure of mouth to caecum transit time. Gut 1983; 24: 893–6
   PubMed Web of Science ®Google Scholar
• Korth H, Müller I, Erckenbrecht J F, Wienbeck M. Breath hydrogen as a test for gastrointestinal transit. Hepatogastroenterology 1984; 31: 282–4
   PubMedGoogle Scholar
• Blomquist L, Bark T, Hedenborg G, Svenberg T, Norman A. Comparison between the lactulose/mannitol and 51Cr-ethylenediaminetetraacetic acid/14C-mannitol methods for intestinal permeability. Scand J Gastroenterol 1993; 28: 274–80
   PubMed Web of Science ®Google Scholar
• Laker M F, Bull H J, Menzies IS. Evaluation of mannitol for use as a probe marker of gastrointestinal permeabilityin man. Eur J Clin Invest 1982; 12: 485–91
   PubMed Web of Science ®Google Scholar
• Fotherby K J, Wraight E P, Neale G. 51Cr-EDTA/14C-mannitol intestinal permeability test. Clinical use in the screening of coeliac disease. Scand J Gastroenterol 1988; 23: 171–7
   PubMed Web of Science ®Google Scholar
• Jenkins A P, Menzies I S, Nukajam W S, Creamer B. The effect of ingested lactulose on absorption of L-rhamnose, D-xylose, and 3-O-methyl-D-glucose in subjects with ileostomies. Scand J Gastroenterol 1994; 29: 820–5
   PubMed Web of Science ®Google Scholar
• Laker M F, Menzies IS. Increase in human intestinal permeability following ingestion of hypertonic solutions. J Physiol (Lond) 1977; 265: 881–94
   Google Scholar
• Bjarnason I, Maxton D, Reynolds A P, Catt S, Peters T J, Menzies IS. Comparison of four markers of intestinal permeability in control subjects and patients with coeliac disease. Scand J Gastroenterol 1994; 29: 630–9
   PubMed Web of Science ®Google Scholar
• Aabakken L. 51Cr-ethylenediaminetetraacetic acid absorption test. Methodologic aspects. Scand J Gastroenterol 1989; 24: 351–8
   PubMed Web of Science ®Google Scholar
• Andre C, Descos L, Minaire Y. Comparison between lactulose-mannitol test and 51Cr-labelled ethylene diamine tetra-acetate test in inflammatory bowel diseases. Hepatogastroenterology 1990; 37: 113–7, Suppl 2
   PubMedGoogle Scholar
• Peeters M, Hiele M, Ghoos Y, Huysmans V, Geboes K, Vantrappen G, et al. Test conditions greatly influence permeation of water soluble molecules through the intestinal mucosa: need for standardisation. Gut 1994; 35: 1404–8
   PubMed Web of Science ®Google Scholar