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Original Article

Protective Effect of Teprenone on Blood Flow and Incidence of Histologic Lesions in Rat Gastric Mucosa after Hemorrhage and Retransfusion

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Pages 326-333 | Received 07 Mar 1995, Accepted 15 Sep 1995, Published online: 08 Jul 2009

References

  • Murakami M, Oketani K, Fujisaki H, Wakabayashi T, Ohgo T. Antiulcer effect of geranylgeranylacetone, a new acyclic polyisoprenoid on experimentally induced gastric and duodenal ulcers in rats. Arzneimittelforsch 1981; 31: 799–804
  • Arakawa T, Yamada H, Nakamura A, Nebiki H, Fukuda T, Nakamura H, et al. Gastric cytoprotection by tetraprenylacetone in human subjects. Digestion 1988; 39: 111–7
  • Terano A, Hiraishi H, Ota S, Sugimoto T. Geranylgeranylacetone, a novel anti-ulcer drug, stimulates mucus synthesis and secretion in rat gastric cultured cells. Digestion 1986; 33: 206–10
  • Terano A, Shiga J, Hiraishi H, Ota S, Sugimoto T. Protective action of tetraprenylacetone against ethanol-induced damage in rat gastric mucosa. Digestion 1986; 35: 182–8
  • Bilski J, Murty V LN, Nadziejko C, Sarosiek J, Aono M, Moriga M, et al. Protection against alcohol-induced gastric mucosal injury by geranylgeranylacetone: effect of indomethacin. Digestion 1988; 41: 22–33
  • Cheung L Y, Ashley S W. Gastric blood flow and mucosal defense mechanisms. Clin Invest Med 1987; 10: 201–8
  • Kunisaki C, Sugiyama M. Effect of teprenone on acute gastric mucosal lesions induced by cold-restraint stress. Digestion 1992; 53: 45–53
  • Kurihara T, Akimoto M, Kurokawa K, Ishiguro H, Niimi A, Maeda A, et al. Effects of a gastric mucosal protecting agent in rats with liver cirrhosis. J Gastroenterol Hepatol 1992; 7: 405–10
  • Sakai M, Sagara K, Fujiyama S, Murata H, Sato T. Gastric mucosal hexosamine content in various liver diseases. Hepatogastroenterol 1991; 38: 302–6
  • Starlinger M, Jakesz R, Matthews J B, Yoon Ch, Schiessel R. The relative importance of HCO3- and blood flow in the protection of rat gastric mucosa during shock. Gastroenterology 1981; 81: 732–5
  • Wallace J L, Hogaboam C M, McKnight G W. Platelet-activating factor mediates gastric damage induced by hemorrhagic shock. Am J Physiol 1990; 259: G140–6
  • Urakawa T, Nagahata Y, Azumi Y, Itoh A, Sano I, Takeda K, et al. The mechanism of acute gastric ulcer after induced hemorrhagic shock. Scand J Gastroenterol 1989; 24: 193–201
  • Binnaka T, Yamaguchi T, Kubota Y, Hirohara J, Mizuno T, Sameshima Y. Gastric hemodynamic disturbance induced by hemorrhagic shock in rats. Role of platelet-activating factor. Scand J Gastroenterol 1990; 25: 555–62
  • Hachiya A, Bessho M. Relationship of blood flow to antral lesion incidence in rat gastric mucosa after hemorrhage and retransfusion. Am J Physiol 1994; 266: G1011–6
  • Sato N, Kamada T, Shichiri M, Kawano S, Abe H, Hagihara B. Measurement of hemoperfusion and oxygen sufficiency in gastric mucosa in vivo. Gastroenterology 1979; 76: 814–9
  • Lowry O H, Rosebrough N J, Farr L, Randall R J. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265–75
  • Itoh M, Paulsen G, Guth P H. Hemorrhagic shock and acid gastric injury in the rat. Comparison of gross and histologic findings. Gastroenterology 1986; 90: 1103–10
  • Yasue N, Guth P H. Role of exogenous acid and retransfusion in hemorrhagic shock-induced gastric lesions in the rat. Gastroenterology 1988; 94: 1135–43
  • Murakami M, Moriga M, Miyake T, Uchino H. Contact electrode method in hydrogen clearance technique: a new method for determination of regional gastric mucosal blood flow in animals and humans. Gastroenterology 1982; 82: 457–67
  • Angerson W J, Geraghty J G, Carter D C. An autoradiographic study of regional distribution of gastric mucosal blood flow. Am J Physiol 1988; 254: G566–74
  • Fujimoto M, Yamanaka T, Bessho M, Igarashi T. Effects of geranyl-geranylacetone on gastrointestinal secretion in rats. Eur J Pharmacol 1982; 77: 113–8
  • Smith S M, Grisham M B, Manci E A, Granger D N, Kvietys P R. Gastric mucosal injury in the rat: role of iron and xanthine oxidase. Gastroenterology 1987; 92: 950–6
  • Kobayashi S, Ishibashi C, Morita A, Masuda H, Ogiso A. Anti-ulcer activities of (E,Z,E)-7-hydroxymethyl-3,11,15-trimethyl-2,6,10,14-hexadecatetraen-1-ol (CS-684), a new acyclic diterpene alcohol from a Thai medicinal plant, on experimental acute gastric and duodenal ulcers. Pharmacometrics (Oyo Yakuri) 1982; 24: 599–607
  • Menguy R, Masters Y F. Mechanism of stress ulcer. II. Differences between the antrum, corpus, and fundus with respect to the effects of complete ischemia on gastric mucosal energy metabolism. Gastroenterology 1974; 66: 509–16
  • Asaka M, Ohtaki T, Kato M, Kudo M, Kimura T, Meguro T, et al. Causal role of Helicobacter pylori in peptic ulcer relapse. J Gastroenterol 1994; 29(Suppl VII)134–8
  • Elta G H, Appleman H D, Behler E M, Wilson J AP, Nostrant T J. A study of the correlation between endoscopic and histological diagnosis in gastroduodenitis. Am J Gastroenterol 1987; 82: 749–53
  • Price A B. The Sydney System: histological division. J Gastroenterol Hepatol 1991; 6: 209–22

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