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Original Article

Gastric Emptying and First-Pass Metabolism of Ethanol in Elderly Subjects with and without Atrophic Gastritis

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Pages 671-677 | Received 15 Apr 1995, Accepted 30 Dec 1995, Published online: 08 Jul 2009

References

  • Caballeria J, Frezza M, Hernandez‐Munoz R, DiPadova C, Lorsten A, Baraona E, et al. The gastric origin of the first pass metabolism of ethanol in man: effects of gastrectomy. Gastroenterology 1989; 97: 1205–9
  • Frezza M, DiPadova C, Pozzato G, Terpin M, Baraona E, Lieber C S. High blood alcohol levels in women: the role of decreased gastric alcohol dehydrogenase activity and first pass metabolism. N Engl J Med 1990; 322: 95–9
  • Seitz H K, Egerer G, Simanowski V A, Waldherr R, Eckey R, Agarwal D P, et al. Human gastric alcohol dehydrogenase activity: effect of age, sex and alcoholism. Gut 1993; 34: 1433–7
  • Seitz H K, Veith S, Czygan P, Boesche J, Simon B H, Gugler R, et al. In vivo interactions between H2‐receptor antagonists and ethanol metabolism in man and in rats. Hepatology 1984; 4: 1231–4
  • Seitz H K, Simanowski U A, Egerer G, Waldrherr R, Örtl U. Human gastric alcohol dehydrogenase: in vitro characteristics and effect of cimetidine. Digestion 1992; 59: 80–5
  • Caballeria J, Baraona E, Roadmilans M, Lieber C S. Effects of cimetidine on gastric alcohol dehydrogenase activity and blood levels of ethanol. Gastroenterology 1989; 96: 388–92
  • DiPadova C, Worner T M, Julkunen R J K, Lieber C S. Effects of fasting and chronic ethanol consumption on the first pass metabolism of ethanol. Gastroenterology 1987; 92: 1169–73
  • Levitt M D, Doizaki W, Leviar A S. Hypothesis: metabolic activity of the colonic bacteria influences organ injury from ethanol. Hepatology 1992; 2: 598–600
  • Seitz H K, Simanowski U A, Garzon F T, Rideout J M, Peters T J, Koch A, et al. Possible role of acetaldehyde in ethanol‐related rectal cocarcinogenesis in the rat. Gastroenterology 1990; 98: 406–13
  • Baraona E, Julkenen R, Tannenbaum L, Lieber C S. Role of intestinal bacteria overgrowth in ethanol production and metabolism in the rat. Gastroenterology 1986; 90: 103–10
  • Saltzman J R. Epidemiology and natural history of atrophic gastritis. Chronic gastritis and hypochlorhydria in the elderly, P R Holt, R M Russell. CRC Press, Boca Raton, FL 1993; 31–47
  • Klein S, Iber F. Alcoholism and associated malnutrition in the elderly. Nutrition 1991; 7: 75–81
  • Samloff I M, Varis K. Ihamaki initials, and next four names please! Relationships among serum pepsinogen I, serum pepsinogen II, and gastric mucosal histology. Gastroenterology 1982; 83: 204
  • Baron J H. Gastric function tests. Chronic duodenal ulcer, C Wastell. Appleton‐Century‐Crofts, New York 1972; 82–114
  • Cutter A F, Havstad S, Ma C K, Blaser M J, Perez G I, Schubert T T. Accuracy of invasive and noninvasive tests to diagnose Helicobacter pylori infection. Gastroenterology 1995; 109: 138–42
  • Bucher T, Redeteski H. Eine spezifische photometrische Bestimmung von Äthylalkohol auf fermentativem Wege. Klin Wochenschr 1951; 29: 615
  • Datz F L, Christian P E, Hutson W R, Moovre J G, Morton K A. Physiological and pharmacological interventions in radionuclide imaging of the tubular gastrointestinal tract. Semin Nucl Med 1991; 21: 140–52
  • Lowry O H, Rosebrough N J, Farr A L, Randall R. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193: 265–70
  • Batra S C, Yazdy A M, Gentry R T, Korsten M A, Lieber C S. First pass metabolism of ethanol persists in hamsters despite the absence of gastric alcohol dehydrogenase [abstract]. Gastroenterology 1993; 104: A875
  • Levitt M D. Do histamine‐2‐receptor antagonists influence the metabolism of alcohol?. Ann Intern Med 1993; 118: 564–5
  • Holt S. Observations on the relation between alcohol absorption and the rate of gastric emptying. CMA J 1981; 124: 267–77
  • Egerer G, Krämer S, Leucht T, Simanowski U A, Seitz H K. Chronic atrophic gastritis results in decreased gastric alcohol dehydrogenase activity [abstract]. Alcoholism Clin Exp Res 1992; 16: 606
  • Moreno A, Pares X. Purification and characterization of a new alcohol dehydrogenase from human stomach. J Biol Chem 1991; 266: 1128–33
  • Roine R P, Gentry T, Lim R T, Baraona E, Lieber C S. Effect of concentration of ingested ethanol on blood alcohol levels. Alcoholism Clin Exp Res 1991; 15: 734–8
  • Gupta A M, Korsten M A, Gentry R T, Lieber C S. Eradication of Helicobacter pylori increases antral gastric alcohol dehydrogenase (ADH) activity. Gastroenterology 1993; 106: A695
  • Salmela K S, Roine R P, Koivisto T, Höök‐Nikanne Kosunen T U, Salaspuro M. Characteristics of Helicobacter pylori alcohol deydrogenase. Gastroenterology 1993; 105: 325–30
  • Osswald B R, Simanowski U A, Arce L, Aderjan R, Egerer G, Waldherr R, et al. Helicobacter pylori infection decreases first pass metabolism of ethanol in man. Gastroenterology 1994; 106: A956
  • Lim R T, Gentry T, Ito D, Yokoyama H, Baraona E, Lieber C S. First pass metabolism of ethanol is predominantly gastric. Alcoholism Clin Exp Res 1993; 17: 1337–44

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