Bile Acids in Health and Disease

References

• Dam H. Nutritional aspects of gallstone formation with particular reference to alimentary production of gallstones in laboratory animals. World Rev Nutr Dietetics 1969; 11: 199–239
   PubMedGoogle Scholar
• Dam H, Kruse I, Kallehauge H E, Hartkopp O E, Jensen M K. Studies on human bile. Scand J Clin Lab Invest 1966; 18: 385–404
   PubMed Web of Science ®Google Scholar
• Dam H. Determinants of cholesterol cholelithiasis in man and animals. Am J Med 1971; 51: 596–613
   PubMed Web of Science ®Google Scholar
• Thistle J L, Schoenfleld L J. Induced alteration of bile composition in humans with cholelithiasis. J Lab Clin Med 1969; 74: 1020–1, (Abstract)
   Google Scholar
• Hegardt F G, Dam H. The solubility of cholesterol in aqueous solutions of bile salts and lecithin. Z Ernährungswiss 1971; 10: 223–33
   PubMedGoogle Scholar
• Admirand W H, Small D M. The physiochemical basis of cholesterol gallstone formation in man. J Clin Invest 1968; 47: 1043–52
   PubMed Web of Science ®Google Scholar
• Holzbach R T, Marsh M, Olszewski M, Holan K. Cholesterol solubility in bile: evidence that supersaturated bile is frequent in healthy man. J Clin Invest 1973; 52: 1467–79
   PubMed Web of Science ®Google Scholar
• Carey M C, Small D M. The physical chemistry of cholesterol solubility in bile: relationship to gallstone formation and dissolution in man. J Clin Invest 1978; 61: 998–1026
   PubMed Web of Science ®Google Scholar
• Thistle J L, Hofmann A F. Efficacy and specificity of chenodeoxycholic acid therapy for dissolving gallstones. N Engl J Med 1973; 289: 655–9
   PubMed Web of Science ®Google Scholar
• Pedersen L. Medical treatment of gall-stones. Ugeskr Læger 1975; 137: 1569–74
   PubMedGoogle Scholar
• Pedersen L, Arnfred T, Thaysen E H. Cholesterol kinetics in patients with cholesterol gallstones before and during chenodeoxycholic acid treatment. Scand J Gastroenterol 1974; 9: 787–91
   PubMed Web of Science ®Google Scholar
• Pedersen L, Arnfred T, Thaysen E H. Turnover of plasma cholesterol in patients with cholesterol gallstones. Acta Med Scand 1975; 197: 421–5
   PubMedGoogle Scholar
• Pedersen L, Arnfred T. Kinetics and pool size of chenodeoxycholic acid in cholesterol gallstone patients. Scand J Gastroenterol 1975; 10: 557–60
   PubMed Web of Science ®Google Scholar
• Arnfred T, Pedersen L. Semiquantitative measurement of lithocholic acid compounds in bile from patients with gallstones, before and during treatment with chenoeoxycholic acid. Scand J Gastroenterol 1976; 11: 497–504
   PubMed Web of Science ®Google Scholar
• Bremmelgaard A, Pedersen L. Bile acids in bile during long-term chenodeoxycholic acid treatment. Scand J Gastroenterol 1976; 11: 161–5
   PubMed Web of Science ®Google Scholar
• Wheeler H O. Pathogenesis of gallstones. Gastrointestinal disease, 2nd ed, M H Sleisenger, J S Fordtran. WB Saunder, Philadelphia 1978; 1284–93
   Google Scholar
• Sauerbruch T, Delius M, Paumgartner G, Holl J, Wess O, Weber W, et al. Fragmentation of gallstones by extracorporeal shock waves. N Engl J Med 1986; 314: 818–22
   PubMed Web of Science ®Google Scholar
• Brøns J H, Damgaard B, Rasmussen S G, Juul N, Højgaard L, Kehlet H, et al. Extracorporeal shock wave lithotripsy for crushing gall stones. A preliminary report. Ugeskr Læger 1991; 153: 332–5
   PubMedGoogle Scholar
• The East-Danish Gallstone Study Group. Bile acid therapy versus placebo after extracorporeal shock wave lithotripsy. Aliment Pharmacol Ther.
   Google Scholar
• Schoenfield L J, Berci G, Carnovale R L, Casarella W, Caslowitz P, Chumley D, et al. The effect of ursodiol on the efficacy and safety of extracorporeal shock-wave lithotripsy of gallstones: the Dornier national biliary lithotripsy study. N Engl J Med 1990; 323: 1239–45
   PubMed Web of Science ®Google Scholar
• Wingate D L, Krag E, Mekhjian H S, Phillips S F. Relationships between ion and water movement in the human jejunum, ileum and colon during perfusion with bile acids. Clin Sci Mol Med 1973; 45: 593–606
   PubMedGoogle Scholar
• Oddsson E, Rask-Madsen J, Krag E. Effect of glycochenodeoxycholic acid on unidirectional transepithelial fluxes of electrolytes in the perfused human ileum. Scand J Gastroenterol 1977; 12: 199–204
   PubMed Web of Science ®Google Scholar
• Oddsson E, Rask-Madsen J, Krag E. Transmural ionic fluxes and electrical potential difference in the human jejunum during perfusion with a dihydroxy bile acid. Scand J Gastroenterol 1977; 12: 453–6
   PubMed Web of Science ®Google Scholar
• Oddsson E, Rask-Madsen J, Krag E. A secretory epithelium of the small intestine with increased sensitivity to bile acids in irritable bowel syndrome associated with diarrhoea. Scand J Gastroenterol 1978; 13: 409–16
   Web of Science ®Google Scholar
• Krag B, Krag E. Regional ileitis (Crohn's disease). Electrolyte and water movement in the ileum during perfusion with bile acids. Scand J Gastroenterol 1976; 11: 487–90
   PubMedGoogle Scholar
• Krejs G J, Fordtran J S. Physiology and pathophysiology of ion and water movement in the human intestine. Gastrointestinal disease, 2nd ed., M H Sleisenger, J S Fordtran. WB Saunders, Philadelphia 1978; 297–335
   Google Scholar
• Krag E, Phillips S F. Active and passive bile acid absorption in man. J Clin Invest 1974; 53: 1686–94
   PubMed Web of Science ®Google Scholar
• Stigsby B, Krag E. A computer model simulating the intestinal absorption of bile acids. Scand J Gastroenterol 1984; 19: 802–7
   PubMed Web of Science ®Google Scholar
• Thaysen E H, Bruusgaard A, Eriksen B. Evaluation of the efficiency of bile salt recirculation in patients with terminal ileopathies by means of deoxycholate determination in duodenal aspirates. Scand J Gastroenterol 1970; 5: 39–47
   PubMed Web of Science ®Google Scholar
• Bruusgaard A, Thaysen E H. Increased ratio of glycine/taurine conjugated bile acids in the early diagnosis of terminal ileopathy. Acta Med Scand 1970; 188: 547–8
   PubMedGoogle Scholar
• Fromm H, Hofmann A F. Breath test for altered bile acid metabolism. Lancet 1971; ii: 621–5
   Google Scholar
• Thaysen E H. Diagnostic value of the14C-cholylglycine breath test. Clin Gastroenterol 1977; 6: 227–45
   PubMedGoogle Scholar
• Lenz K, Jensen K B, Jarnum S. Bile acid metabolism and plasma protein turnover in Crohn's disease. Scand J Gastroenterol 1976; 11: 721–7
   PubMed Web of Science ®Google Scholar
• Lenz K. Bile acid metabolism and vitamin 812 absorption in ulcerative colitis. Scand J Gastroenterol 1976; 11: 769–75
   PubMed Web of Science ®Google Scholar
• Linnet K, Nielsen A M. Fasting and postprandial serum concentrations of glycine-and taurine-conjugated bile acids in Crohn's Disease. Scand J Gastroenterol 1983; 18: 433–8
   PubMed Web of Science ®Google Scholar
• Pedersen B H, Simonsen L, Hansen L K, Giese B, Justesen T, Tougaard L, et al. Bile acid malabsorption in patients with an ileum reservoir with a long efferent leg to an anal anastomosis. Scand J Gastroentreol 1985; 20: 995–1000
   PubMed Web of Science ®Google Scholar
• Tougaard L, Giese B, Pedersen B H, Binder V. Bile acid metabolism in patients with Crohn's disease in terminal ileum. Scand J Gastroenterol 1986; 21: 627–33
   PubMed Web of Science ®Google Scholar
• Hylander E, Ladefoged K, Nielsen M L, Nielsen O V, Thale M, Jarnum S. Excretion, deconjugation, and absorption of bile acids after colectomy for ulcerative colitis. Scand J Gastroenterol 1986; 21: 1137–43
   PubMed Web of Science ®Google Scholar
• Jacobsen O, Højgaard L, Møller E H, Wielandt T O, Thale M, Jarnum S, et al. Effect of enterocoated colestyramine on bowel habit after ileal resection: a double-blind crossover study. BMJ 1985; 290: 1315–8
   PubMed Web of Science ®Google Scholar
• Hofmann A F, Poley J R. Cholestyramine treatment of diarrhoea associated with ileal resection. N Engl J Med 1969; 281: 397–402
   PubMed Web of Science ®Google Scholar
• Thaysen E H, Pedersen L. Idiopathic bile acid catharsis. Gut 1976; 17: 965–70
   PubMed Web of Science ®Google Scholar
• Thaysen E H. Idiopathic bile acid diarrhoea reconsidered. Scand J Gastroenterol 1985; 20: 452–6
   PubMed Web of Science ®Google Scholar
• Fine K D, Krejs G J, Fordtran J S. Diarrhoea. Gastrointestinal disease,4th ed., M H Sleisenger, J S Fordtran. WB Saunders, Philadelphia 1989; 290–316
   Google Scholar
• Danö P, Lenz K. Change of bile acid metabolism and absorption of vitamin B12 after intestinal shunt operation in obesity. Scand J Gastroenterol 1974; 9: 159–65
   PubMed Web of Science ®Google Scholar
• Hippe E, Juhl E, Bruusgaard A, Korner B, Quaade F, Baden H. Malabsorption of vitamin B12 in obese patients treated with jejunoileal shunt. Scand J Gastroenterol 1974; 9(Suppl 29)81–83
   PubMedGoogle Scholar
• Danö P, Lenz K, Justesen T. Bile acid metabolism and intestinal bacterial flora after three types of intestinal shunt operation for obesity. Scand J Gastroenterol 1974; 9: 767–74
   PubMed Web of Science ®Google Scholar
• Juhl E, Bruusgaard A, Hippe E, Korner B, Quaade F, Baden H. Vitamin B12 depletion in obese patients treated with jejunoileal shunt. Scand J Gastroenterol 1974; 9: 543–7
   PubMed Web of Science ®Google Scholar
• Bruusgaard A, Sørensen T IA, Justesen T, Krag E. Bile acid metabolism after jejunoileal bypass operation for obesity. Scand J Gastroenterol 1976; 11: 833–8
   PubMed Web of Science ®Google Scholar
• Sørensen T IA, Bruusgaard A, Pedersen L R, Krag E. Lithogenic index of bile after jejunoileal bypass operation for obesity. Scand J Gastroenterol 1977; 12: 449–51
   PubMed Web of Science ®Google Scholar
• Sørensen T IA, Krag E. Fat digestion after jejunoileal bypass operation for obesity. Scand J Gastroenterol 1976; 11: 491–5
   PubMed Web of Science ®Google Scholar
• Sørensen T IA, Jensen L I, Klein H C, Andersen B, Petersen O, Laursen K, et al. Risk of gallstone formation after jejunoileal bypass increases more with a 1:3 than with a 3:1 jejunoileal ratio. Scand J Gastroenterol 1980; 15: 979–84
   PubMed Web of Science ®Google Scholar
• Sørensen T IA, Bruusgaard A, Andersen A N, Andersen B. Serum levels and clearance of bile acids are unaffected by jejunoileal bypass with 3:1 or 1:3 jejunoileal ratio. Scand J Gastroenterol 1981; 16: 705–11
   PubMed Web of Science ®Google Scholar
• Sørensen T IA, Bruusgaard Andersen A, Pedersen L R, Andersen B. Cholesterol saturation of the bile after jejunoileal bypass increases more with a 1:3 than with 3:1 jejunoileal ratio. Scand J Gastroenterol 1981; 16: 945–50
   PubMed Web of Science ®Google Scholar
• Sørensen T IA, Bruusgaard A, Andersen B. Bile acid malabsorption after jejunoileal bypass is less compensated for with a 1:3 than with a 3:1 jejunoileal ratio. Scand J Gastroenterol 1982; 17: 473–80
   PubMedGoogle Scholar
• Sørensen T IA, Hylander E, Miettinen T A. Faecal steroids after jejunoileal bypass with 3:1 or 1:3 jejunoileal ratio. Scand J Gastroenterol 1985; 20: 205–8
   PubMedGoogle Scholar
• Sørensen T IA, Andersen B, Hylander E, Jensen L I, Laursen K, Klein H C, et al. Prospective study of malabsorption induced risk of gallstone formation in relation to fall in plasma cholesterol. Gut 1988; 29: 108–13
   PubMedGoogle Scholar
• Sørensen T IA, Miettinen T A, Andersen B. Dissociation of changes in plasma cholesterol and hepatic cholesterol synthesis, assessed by precursors in bile, after jejunoileal bypass with 3:1 and 1:3 jejunoileal ratio. Scand J Gastroenterol 1989; 24: 1049–54
   PubMed Web of Science ®Google Scholar
• Bremmelgaard A, Sjövall J. Bile acid profiles in urine of patients with liver diseases. Eur J Clin Invest 1979; 9: 341–8
   PubMed Web of Science ®Google Scholar
• Bremmelgaard A, Sjövall J. Hydroxylation of cholic, chenodeoxycholic, and deoxycholic acids in patients with intrahepatic cholestasis. J Lipid Res 1980; 21: 1072–81
   PubMed Web of Science ®Google Scholar
• Peterslund N A. The concentration of serum bile acids during the course of acute hepatitis B. Scand J Gastroenterol 1980; 15: 405–10
   PubMed Web of Science ®Google Scholar
• Kelbæk H, Linnet K, Stimpel H, Glenthøj J, Thomsen H F, Bahnsen M. Cholecystokinin-stimulated and postprandial serum concentrations of bile acids in alcoholic liver cirrhosis. Scand J Gastroenterol 1984; 19: 655–60
   PubMed Web of Science ®Google Scholar
• Bremmelgaard A, Almé B. Analysis of plasma bile acid profiles in patients with liver diseases associated with cholestasis. Scand J Gastroenterol 1980; 15: 593–600
   PubMed Web of Science ®Google Scholar
• Linnet K, Kelbæk H. The patterns of glycine and taurine conjugates of bile acids in serum in hepatobiliary disease. Scand J Gastroenterol 1982; 17: 919–24
   PubMed Web of Science ®Google Scholar
• Bremmelgaard A, Ranek L, Bahnsen M, Andreasen P B, Christensen E. Cholic acid conjugation test and quantitative liver function in acute liver failure. Scand J Gastroenterol 1983; 18: 797–802
   PubMed Web of Science ®Google Scholar
• Linnet K, Andersen J R. Differential diagnostic value in hepatobiliary disease of serum conjugated bile acid concentrations and some routine liver tests assessed by discriminant analysis. Clin Chim Acta 1983; 127: 217–28
   PubMedGoogle Scholar
• Rickers H, Christensen M, Arnfred T, Dige U, Thaysen E H. The diagnostic value of fasting serum total bile acid concentration in patients with suspected liver disease. Scand J Gastroenterol 1982; 17: 565–70
   PubMed Web of Science ®Google Scholar
• Linnet K, Kelbæk H, Bahnsen M. Diagnostic values of fasting and postprandial concentrations in serum of 3α-hydroxy-bile acids and gamma-glutamyl transferase in hepatobiliary disease. Scand J Gastroenterol 1983; 18: 49–56
   PubMed Web of Science ®Google Scholar
• Linnet K, Kelbæk H, Frandsen P. Predictive value of the concentration in serum of total 3α-hydroxy bile acids in the diagnosis of hepatobiliary disease. Scand J Gastroenterol 1982; 17: 263–8
   PubMed Web of Science ®Google Scholar
• Hofmann A F. The enterohepatic circulation of bile acids in health and disease. Gastrointestinal disease,4th ed., M H Sleisenger, J S Fordtran. WB Saunders, Philadelphia 1989; 144–61
   Google Scholar
• Christensen E, Bremmelgaard A, Bahnsen M, Andreasen P B, Tygstrup N. Prediction of fatality in fulminant hepatic failure. Scand J Gastroenterol 1984; 19: 90–96
   PubMed Web of Science ®Google Scholar
• Larsen J A, Krarup N, Thomsen Ø S. The effect of glucagon, dibutyrylic cyclic AMP and theophylline on bile production in the cat. Acta Physiol Scand 1979; 106: 23–7
   PubMedGoogle Scholar
• Thomsen Ø S, Larsen J A. The effect of glucagon, dibutyrylic cyclic AMP and insulin on bile production in the intact rat and the perfused rat liver. Acta Physiol Scand 1981; 111: 23–30
   PubMedGoogle Scholar
• Thomsen Ø S, Larsen J A. Comparison of vanadate and ouabain effects on liver hemodynamics and bile production in the perfused rat liver. J Pharmacol Exp Ther 1982; 221: 197–205
   PubMedGoogle Scholar
• Thomsen Ø S, Larsen J A. Interaction of insulin, glucagon, and DBcAMP on bile acid-independent bile production in the rat. Scand J Gastroenterol 1982; 17: 687–93
   PubMed Web of Science ®Google Scholar
• Thomsen Ø S. Stimulatory effect of bile acids on insulin-induced choleresis in the rat. Am J Physiol 1983; 244: G301–7
   Google Scholar
• Thomsen Ø S. Mechanism and regulation of hepatic bile production. Scand J Gastroenterol 1984; 19(Suppl 97)1–52
   PubMedGoogle Scholar
• Scharschmidt B F. Bile formation and gallbladder and bile duct function. Gastrointestinal disease,4th ed., M H Sleisenger, J S Fordtran. WB Saunders, Philadelphia 1989; 1656–68
   Google Scholar
• Westergaard H, Dietschy J M. Delineation of the dimensions and permeability characteristics of the two major diffusion barriers to passive mucosal uptake in the rabbit intestine. J Clin Invest 1974; 54: 718–32
   PubMed Web of Science ®Google Scholar
• Westergaard H, Dietschy J M. The mechanism whereby bile acid micelles increase the rate of fatty acid and cholesterol uptake into the intestinal mucosal cell. J Clin Invest 1976; 58: 97–108
   PubMed Web of Science ®Google Scholar
• VanDyke R W. Mechanisms of digestion and absorption of food. Gastrointestinal disease,4th ed., M H Sleisenger, J S Fordtran. WB Saunders, Philadelphia 1989; 1062–88
   Google Scholar
• Westergaard H. Duodenal bile acid concentrations in fat malabsorption syndromes. Scand J Gastroenterol 1977; 12: 115–22
   PubMed Web of Science ®Google Scholar
• Andersen J R, Bendtsen F, Ovesen L, Pedersen N T, Rune S, Tage-Jensen U. Pancreatic insufficiency. Int J Pancreatol 1990; 6: 263–70
   PubMedGoogle Scholar
• Bruusgaard A. Quantitative determination of the major 3-hydroxy bile acids in biological material after thin-layer chromatographic separation. Clin Chim Acta 1970; 28: 495–504
   PubMed Web of Science ®Google Scholar
• Bruusgaard A, Sørensen H, Gilhuus-Moe C C, Skålhegg B A. Bile acid determination with different preparations of 3α-hydroxysteroid dehydrogenase. Clin Chim Acta 1977; 77: 387–95
   PubMed Web of Science ®Google Scholar
• Bruusgaard A, Sørensen H, Sylvest J. An easy procedure for determination of molar activity (or specific activity) of bile acids in bile. Clin Chim Acta 1979; 99: 247–51
   PubMedGoogle Scholar
• Bruusgaard A, Pedersen L R, Sørensen H. Determination of total 3α-hydroxy bile acids in serum. Clin Chim Acta 1979; 93: 1–8
   PubMed Web of Science ®Google Scholar
• Malchow-Møller A, Arffmann S, LaRusso N F, Krag E. Enzymatic determination of total 3α-hydroxy bile acids in faeces. Scand J Gastroenterol 1982; 17: 331–33
   PubMed Web of Science ®Google Scholar
• Bremmelgaard A, Bremmelgaard A. Bacterial metabolization of taurolithocholic acid 3-α-sulfate. Acta Path Microbiol Scand Sect B. 1974; 82: 537–40
   Google Scholar
• Linnet K. A high-pressure liquid chromatographic-enxymatic assay for glycine and taurine conjugates of cholic, chenodeoxycholic and deoxycholic acid in serum. Scand J Clin Lab Invest 1982; 42: 455–60
   PubMed Web of Science ®Google Scholar
• Linnet K. Postprandial plasma concentrations of glycine and taurine conjugated bile acids in healthy subjects. Gut 1983; 24: 249–52
   PubMed Web of Science ®Google Scholar
• Linnet K, Andersen J R, Hesselfeldt P. Cencentrations of glycine-and taurine-conjugated bile acids in portal and systemic venous serum in man. Scand J Gastroenterol 1984; 19: 575–8
   PubMed Web of Science ®Google Scholar
• Karlaganis G, Bremmelgaard A, Karlaganis V, Sjövall J. Precursor of 27-nor-5β-cholestane-3α, 7α, 12α, 24, 25-pentol in man. J Steroid Biochem 1983; 18: 725–9
   PubMedGoogle Scholar
• Arffmann S, Højgaard L, Giese B, Krag E. Effect of oat bran on lithogenic index of bile and bile acid metabolism. Digestion 1983; 28: 197–200
   PubMedGoogle Scholar
• Almé B, Bremmelgaard A, Sjövall J, Thomassen P. Analysis of metabolic profiles of bile acids in urine using a lipophilic anion exchanger and computerized gas-liquid chromatography-mass spectrometry. J Lipid Research 1977; 18: 339–62
   PubMed Web of Science ®Google Scholar