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Research Article

The association of interleukin-18 promoter polymorphisms and serum levels with duodenal ulcer, and their correlations with bacterial CagA and VacA virulence factors

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Pages 584-592 | Received 16 Feb 2013, Accepted 27 Mar 2013, Published online: 09 Jun 2013

References

  • Akhiani AA, Schon K, Lycke N. Vaccine-induced immunity against Helicobacter pylori infection is impaired in IL-18-deficient mice. J Immunol 2004;173:3348–56.
  • Anyona SB, Kempaiah P, Raballah E, Ouma C, Were T, Davenport GC, et al. Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality. Infect Immun 2011;79: 4923–32.
  • Bai J, Zhang Y, Lin M, Zeng X, Wang Z, Shen J, et al. Interleukin-18 gene polymorphisms and haplotypes in patients with oral lichen planus: a study in an ethnic Chinese cohort. Tissue Antigens 2007;70:390–7.
  • Bauditz J, Ortner M, Bierbaum M, Niedobitek G, Lochs H, Schreiber S. Production of IL-12 in gastritis relates to infection with Helicobacter pylori. Clin Exp Immunol 1999;117: 316–23.
  • Benoit BN, Kobayashi M, Kawakubo M, Takeoka M, Sano K, Zou J, et al. Role of ASC in the mouse model of Helicobacter pylori infection. J Histochem Cytochem 2009;57:327–38.
  • Bossu P, Ciaramella A, Moro ML, Bellincampi L, Bernardini S, Federici G, et al. Interleukin 18 gene polymorphisms predict risk and outcome of Alzheimer's disease. J Neurol Neurosurg Psychiatry 2007;78:807–11.
  • Caruso R, Pallone F, Monteleone G. Emerging role of IL-23/IL-17 axis in H. pylori-associated pathology. World J Gastroenterol 2007;13:5547–51.
  • Cendron L, Zanotti G. Structural and functional aspects of unique type IV secretory components in the Helicobacter pylori cag-pathogenicity island. FEBS J 2011;278: 1223–31.
  • Chen DY, Hsieh CW, Chen KS, Chen YM, Lin FJ, Lan JL. Association of interleukin-18 promoter polymorphisms with WHO pathological classes and serum IL-18 levels in Chinese patients with lupus nephritis. Lupus 2009;18:29–37.
  • Day AS, Su B, Ceponis PJ, Jones NL, Yau E, Sieveking D, et al. Helicobacter pylori infection induces interleukin-18 production in gastric epithelial (AGS) cells. Dig Dis Sci 2004; 49:1830–5.
  • de Bernard M, D’Elios MM. The immune modulating activity of the Helicobacter pylori HP-NAP: friend or foe?Toxicon 2010;56:1186–92.
  • D’Elios MM, Amedei A, Benagiano M, Azzurri A, Del Prete G. Helicobacter pylori, T cells and cytokines: the “dangerous liaisons”. FEMS Immunol Med Microbiol 2005;44:113–9.
  • D’Elios MM, Amedei A, Del Prete G. Helicobacter pylori antigen-specific T-cell responses at gastric level in chronic gastritis, peptic ulcer, gastric cancer and low-grade mucosa-associated lymphoid tissue (MALT) lymphoma. Microbes Infect 2003;5:723–30.
  • D’Elios MM, Andersen LP. Inflammation, immunity, and vaccines for Helicobacter pylori. Helicobacter 2009;14(Suppl 1):21–8.
  • Dzierzanowska-Fangrat K, Michalkiewicz J, Cielecka-Kuszyk J, Nowak M, Celinska-Cedro D, Rozynek E, et al. Enhanced gastric IL-18 mRNA expression in Helicobacter pylori-infected children is associated with macrophage infiltration, IL-8, and IL-1 beta mRNA expression. Eur J Gastroenterol Hepatol 2008;20:314–9.
  • Eskandari-Nasab E, Sepanjnia A, Moghadampour M, Hadadi-Fishani M, Rezaeifar A, Asadi-Saghandi A, et al. Circulating levels of interleukin (IL)-12 and IL-13 in Helicobacter pylori-infected patients, and their associations with bacterial CagA and VacA virulence factors. Scand J Infect Dis 2013;45:342–9.
  • Farinati F, Cardin R, Cassaro M, Bortolami M, Nitti D, Tieppo C, et al. Helicobacter pylori, inflammation, oxidative damage and gastric cancer: a morphological, biological and molecular pathway. Eur J Cancer Prev 2008;17:195–200.
  • Fera MT, Carbone M, Buda C, Aragona M, Panetta S, Giannone M, et al. Correlation between Helicobacter pylori infection and IL-18 mRNA expression in human gastric biopsy specimens. Ann N Y Acad Sci 2002;963:326–8.
  • Garrote JA, Gomez-Gonzalez E, Bernardo D, Arranz E, Chirdo F. Celiac disease pathogenesis: the proinflammatory cytokine network. J Pediatr Gastroenterol Nutr 2008;47(Suppl 1):S27–32.
  • Giedraitis V, He B, Huang WX, Hillert J. Cloning and mutation analysis of the human IL-18 promoter: a possible role of polymorphisms in expression regulation. J Neuroimmunol 2001;112:146–52.
  • Haghshenas MR, Hosseini SV, Mahmoudi M, Saberi-Firozi M, Farjadian S, Ghaderi A. IL-18 serum level and IL-18 promoter gene polymorphism in Iranian patients with gastrointestinal cancers. J Gastroenterol Hepatol 2009;24:1119–22.
  • Hashemi M, Eskandari-Nasab E, Fazaeli A, Rezaei H, Mashhadi MA, Arbabi F, et al. Bi-directional PCR allele-specific amplification (bi-PASA) for detection of caspase-8 − 652 6N ins/del promoter polymorphism (rs3834129) in breast cancer. Gene 2012;505:176–9.
  • Hong SN, Jo S, Jang JH, Choi J, Kim S, Ahn SY, et al. Clinical characteristics and the expression profiles of inflammatory cytokines/cytokine regulatory factors in asymptomatic patients with nodular gastritis. Dig Dis Sci 2012;57:1486–95.
  • Jafarzadeh A, Rezayati MT, Nemati M. Specific serum immunoglobulin G to H. pylori and CagA in healthy children and adults (south-east of Iran). World J Gastroenterol 2007; 13:3117–21.
  • Kawabata T, Ichikura T, Majima T, Seki S, Chochi K, Takayama E, et al. Preoperative serum interleukin-18 level as a postoperative prognostic marker in patients with gastric carcinoma. Cancer 2001;92:2050–5.
  • Kimang'a A, Revathi G, Kariuki S, Sayed S, Devani S, Vivienne M, et al. IL-17A and IL-17F gene expression is strongly induced in the mucosa of H. pylori-infected subjects from Kenya and Germany. Scand J Immunol 2010;72:522–8.
  • Kohno K, Kataoka J, Ohtsuki T, Suemoto Y, Okamoto I, Usui M, et al. IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12. J Immunol 1997; 158:1541–50.
  • Lewontin RC. The detection of linkage disequilibrium in molecular sequence data. Genetics 1995;140:377–88.
  • Lin DY, Huang BE. The use of inferred haplotypes in downstream analyses. Am J Hum Genet 2007;80:577–9.
  • Luzza F, Parrello T, Sebkova L, Pensabene L, Imeneo M, Mancuso M, et al. Expression of proinflammatory and Th1 but not Th2 cytokines is enhanced in gastric mucosa of Helicobacter pylori infected children. Dig Liver Dis 2001;33:14–20.
  • Malfertheiner MV, Kandulski A, Schreiber J, Malfertheiner P. Helicobacter pylori infection and the respiratory system: a systematic review of the literature. Digestion 2011;84:212–20.
  • Massarrat S, Saberi-Firoozi M, Soleimani A, Himmelmann GW, Hitzges M, Keshavarz H. Peptic ulcer disease, irritable bowel syndrome and constipation in two populations in Iran. Eur J Gastroenterol Hepatol 1995;7:427–33.
  • Ming L, Wen Q, Qiao HL, Dong ZM. Interleukin-18 and IL18 − 607A/C and − 137G/C gene polymorphisms in patients with penicillin allergy. J Int Med Res 2011;39:388–98.
  • Mitchell HM, Hazell SL, Li YY, Hu PJ. Serological response to specific Helicobacter pylori antigens: antibody against CagA antigen is not predictive of gastric cancer in a developing country. Am J Gastroenterol 1996;91:1785–8.
  • Molnar B, Galamb O, Sipos F, Leiszter K, Tulassay Z. Molecular pathogenesis of Helicobacter pylori infection: the role of bacterial virulence factors. Dig Dis 2010;28:604–8.
  • Ozen A, Ertem D, Pehlivanoglu E. Natural history and symptomatology of Helicobacter pylori in childhood and factors determining the epidemiology of infection. J Pediatr Gastroenterol Nutr 2006;42:398–404.
  • Queiroz DM, Cunha RP, Saraiva IE, Rocha AM. Helicobacter pylori virulence factors as tools to study human migrations. Toxicon 2010;56:1193–7.
  • Romero-Adrian TB, Leal-Montiel J, Monsalve-Castillo F, Mengual-Moreno E, McGregor EG, Perini L, et al. Helicobacter pylori: bacterial factors and the role of cytokines in the immune response. Curr Microbiol 2010;60:143–55.
  • Sakai K, Kita M, Sawai N, Shiomi S, Sumida Y, Kanemasa K, et al. Levels of interleukin-18 are markedly increased in Helicobacter pylori-infected gastric mucosa among patients with specific IL18 genotypes. J Infect Dis 2008;197:1752–61.
  • Shimoyama A, Saeki A, Tanimura N, Tsutsui H, Miyake K, Suda Y, et al. Chemical synthesis of Helicobacter pylori lipopolysaccharide partial structures and their selective proinflammatory responses. Chemistry 2011;17:14464–74.
  • Siavoshi F, Malekzadeh R, Daneshmand M, Ashktorab H. Helicobacter pylori endemic and gastric disease. Dig Dis Sci 2005;50:2075–80.
  • Stassi G, Arena A, Speranza A, Iannello D, Mastroeni P. Different modulation by live or killed Helicobacter pylori on cytokine production from peripheral blood mononuclear cells. New Microbiol 2002;25:247–52.
  • Takeda K, Tsutsui H, Yoshimoto T, Adachi O, Yoshida N, Kishimoto T, et al. Defective NK cell activity and Th1 response in IL-18-deficient mice. Immunity 1998;8:383–90.
  • Toka FN, Pack CD, Rouse BT. Molecular adjuvants for mucosal immunity. Immunol Rev 2004;199:100–12.
  • Tomita T, Jackson AM, Hida N, Hayat M, Dixon MF, Shimoyama T, et al. Expression of interleukin-18, a Th1 cytokine, in human gastric mucosa is increased in Helicobacter pylori infection. J Infect Dis 2001;183:620–7.
  • Varbanova M, Malfertheiner P. Bacterial load and degree of gastric mucosal inflammation in Helicobacter pylori infection. Dig Dis 2011;29:592–9.
  • Yamauchi K, Choi IJ, Lu H, Ogiwara H, Graham DY, Yamaoka Y. Regulation of IL-18 in Helicobacter pylori infection. J Immunol 2008;180:1207–16.

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