1
Views
5
CrossRef citations to date
0
Altmetric
Original Article

Long-term Histological Outcome in Patients with Chronic Hepatitis C Treated Repeatedly with Interferon alpha-2b without Sustained Response

, &
Pages 383-389 | Received 10 Dec 1993, Accepted 07 Mar 1994, Published online: 08 Jul 2009

References

  • Di Bisceglie A, Goodman Z, Ishak K, Hoofnagle J, Melpolder J, Alter H. Long-term clinical and histopathological follow-up of chronic post transfusion hepatitis. Hepatology 1991; 14: 969–974
  • Mattsson L, Weiland O, Glaumann H. Long-term follow-up of chronic post-transfusion non-A, non-B hepatitis: clinical and histological outcome. Liver 1988; 8: 184–188
  • Tremolada F, Casarin C, Alberti A, Drago C, Tagger A, Ribero M L, Realdi G. Long-term follow-up of non-A, non-B (type C) post-transfusion hepatitis. J Hepatol 1992; 16: 273–281
  • Wejstål R, Widell A, Norkrans G. Hepatitis C virus infection with progression to hepatocellular carcinoma: A report of five prospectively followed patients in Sweden. Scand J Infect Dis 1993; 25: 417–420
  • Tsukuma H, Hiyama T, Tanaka S, Nakao M, Yabuuchi T, Kitamura T, Nakanishi K, Fujimoto I, Inoue A, Yamazaki H, Kawashima T. Risk factors for hepatocellular carcinoma among patients with chronic liver disease. N Engl J Med 1993; 328: 1797–1801
  • Di Bisceglie A, Martin P, Kassianides C, Lisker-Melman M, Murray L WJ, Goodman Z, Banks S, Hoofnagle J. Recombinant interferon alfa therapy for chronic hepatitis C. A randomized, doubleblind, placebo-controlled trial, N Engl J Med 1989; 321: 1506–1510
  • Davis G, Balart L, Schiff E, Lindsay K, Bodenheimer H, Perillo R, Carey W, Jacobson I, Payne J, Dienstag J, VanThiel D, Tamburro C, Lefkowitch J, Albrecht J, Meschievitz C, Ortego T, Gibas A, hepatitis interventional therapy group. Treatment of chronic hepatitis C with recombinant interferon alfa. A multicenter randomized, controlled trial. N Engl J Med 1989; 321: 1501–1506, and the
  • Schvarcz R, Weiland O, Wejstål R, Nokrans G, Fryden A, Foberg U. A randomized controlled open study of interferon alpha-2b treatment of chronic non-A, non-B posttransfusion hepatitis: no correlation of outcome to presence of hepatitis C virus antibodies. Scand J Infect Dis 1989; 21: 617–625
  • Reichard O, Foberg U, Frydén A, Mattsson L, Norkrans G, Sönnerborg A, Wejstål R, Yun Z B, Weiland O. High sustained response rate and clearance of viremia in chronic hepatitis C following tieatment with interferon alpha-2b for 60 weeks. Hepatology 1994; 19: 280–285
  • Shindo M, Di Bisceglie A, Cheung L, Wai-Kuo Shih J, Cristiano K, Feinstone S, Hoofnagle J. Decrease in serum hepatitis C viral RNA during alpha-interferon therapy for chronic hepatitis C. Ann Intern Med 1991; 115: 700–704
  • Schvarcz R, Glaumann H, Weiland O, Norkrans G, Wejstål R, Frydén A. Histological outcome in interferon alpha-2b treated patients with chronic posttransfusion non-A, non-B hepatitis. Liver 1991; 11: 30–38
  • Tine F, Magrin S, Craxi A, Pagliaro L. Interferon for non-A, non-B chronic hepatitis. A meta-analysis of randomised clinical trials. J Hepatol 1991; 13: 192–199
  • Weiland O, Zhang Y, Widell A. Serum HCA RNA levels in patients with chronic hepatitis C given a second course of interferon alpha-2b treatment after relapse following initial treatment. Scand J Infect Dis 1993; 25: 25–30
  • Yun Z B, Lindh G, Weiland O, Johansson B, Sönnerborg A. Detection of hepatitis C virus (HCV) RNA by PCR related to HCV antibodies in serum and liver histology in Swedish blood donors. J Med Virol 1993; 39: 57–61
  • Weiland O, Schvarcz R, Wejstål R, Norkrans G, Frydén A. Therapy of chronic posttransfusion non-A, non-B hepatitis with interferon alpha-2b: Swedish experience. J Hepatol 1990; 11: 57–62
  • International group. Acute and chronic hepatitis revisited. Lancet 1977; 2: 914–919
  • Knodell R G, Ishak K G, Black W C, Chen T S, Craig R, Kaplowitz N, Kiernan T W, Wollman J. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981; 1: 431–435
  • Mattsson L, Weiland O, Glaumann H. Application of a histological scoring system for assessment of histological outcome in patients with chronic posttransfusion non-A, non-B hepatitis with or without antibodies to hepatitis C. Liver 1990; 10: 257–263
  • Hoofnagle J H, Di Bisceglie A M, Shindo M. Antiviral therapy of hepatitis C - present and future. J Hepatol 1993; 17: 130–136
  • Bartolomé J, Castillo I, Quiroga J A, Navas S, Carreno V. Detection of hepatitis C RNA in serum and peripheral blood mononuclear cells. J Hepatol 1993; 17: 90–93
  • Takehara T, Hayashi N, Mita E, Hagiwara H, Ueda K, Katayama K, Kasahara A, Fusamoto H, Kamada T. Detection of the minus strand of hepatitis C virus RNA by reverse transcription and polymerase chain reaction: Implications for hepatitis C virus replication in infected tissue. Hepatology 1992; 15: 387–390
  • Balart L A, Perrillo R, Roddenberry J, Regenstein F, Shim K S, Shieh C, Taylor B, Dash S, Gerber M A. Hepatitis C RNA in liver of chronic hepatitis C patients before and after interferon alfa treatment. Gastroenterology 1993; 104: 1472–1477

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.