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Xenobiotica
the fate of foreign compounds in biological systems
Volume 39, 2009 - Issue 12
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Research Article

Inter-individual difference determinant of prednisolone pharmacokinetics for Japanese renal transplant recipients in the maintenance stage

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Pages 939-945 | Received 12 Jun 2009, Accepted 27 Aug 2009, Published online: 01 Oct 2009

References

  • Bachmann AW, Sedgley TL, Jackson RV, Gibson JN, Young RM, Torpy DJ. (2005). Glucocorticoid receptor polymorphisms and post-traumatic stress disorder. Psychoneuroendocrinology 30:297–306.
  • Bray PJ, Cotton RG. (2003). Variations of the human glucocorticoid receptor gene (NR3C1): pathological and in vitro mutations and polymorphisms. Hum Mutat 21:557–68.
  • Buemann B, Vohl MC, Chagnon M, Chagnon YC, Gagnon J, Perusse L, Dionne F, Depres JP, Tremblay A, Nadeau A, Bouchard C. (1997). Abdominal visceral fat is associated with a BclI restriction fragment length polymorphism at the glucocorticoid receptor gene locus. Obesit Res 5:186–92.
  • Cascorbi I, Gerloff T, Johne A, Meisel C, Hoffmeyer S, Schwab M, Schaeffeler E, Eichelbaum M, Brinkmann U, Roots I. (2001). Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther 69:169–74.
  • Derijk RH, Schaaf MJ, Turner G, Datson NA, Vreugdenhil E, Cidlowski J, De Kloet ER, Emery P, Sternberg EM, Detera-Wadleigh SD. (2001). A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor beta-isoform mRNA is associated with rheumatoid arthritis. J Rheumatol 28:2383–8.
  • Dring MM, Goulding CA, Trimble VI, Keegan D, Ryan AW, Brophy KM, Smyth CM, Keeling PW, O’Donoghue D, O’Sullivan M, O’Morain C, Mahmud N, Wikström AC, Kelleher D, McManus R. (2006). The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease. Gastroenterology 130:341–8.
  • Drocourt L, Ourlin JC, Pascussi JM, Maurel P, Vilarem MJ. (2002). Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes. J Biol Chem 277:25125–32.
  • Dvorak Z, Modriansky M, Pichard-Garcia L, Balaguer P, Vilarem MJ, UlrichováJ, Maurel P, Pascussi JM. (2003). Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation. Mol Pharmacol 64:160–9.
  • El-Sankary W, Plant NJ, Gibson GG, Moore DJ. (2000). Regulation of the CYP3A4 gene by hydrocortisone and xenobiotics: role of the glucocorticoid and pregnane X receptors. Drug Metab Disposit 28:493–6.
  • Fukuen S, Fukuda T, Maune H, Ikenaga Y, Yamamoto I, Inaba T, Azuma J. (2002). Novel detection assay by PCR-RFLP and frequency of the CYP3A5 SNPs, CYP3A5*3 and *6, in a Japanese population. Pharmacogenetics 12:331–4.
  • Gibson GG, Plant NJ, Swales KE, Ayrton A, El-Sankary W. (2002). Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man. Xenobiotica 32:165–206.
  • Karssen AM, Meijer OC, Van der Sandt IC, De Boer AG, De Lange EC, De Kloet ER. (2002). The role of the efflux transporter P-glycoprotein in brain penetration of prednisolone. J Endocrinol 175:251–60.
  • Kimura Y, Selmi C, Leung PS, Mao TK, Schauer J, Watnik M, Kuriyama S, Nishioka M, Ansari AA, Coppel RL, Invernizzi P, Podda M, Gershwin ME. (2005). Genetic polymorphisms influencing xenobiotic metabolism and transport in patients with primary biliary cirrhosis. Hepatology 41:55–63.
  • Koper JW, Stolk RP, De Lange P, Huizenga NA, Molijn GJ, Pols HA, Grobbee DE, Karl M, De Jong FH, Brinkmann AO, Lamberts SW. (1997). Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance. Hum Genet 99:663–8.
  • Majnik J, Patócs A, Balogh K, Tóth M, Rácz K. (2004). A rapid and simple method for detection of Asn363Ser polymorphism of the human glucocorticoid receptor gene. J Steroid Biochem Mol Biol 92:465–8.
  • Miura M, Satoh S, Inoue K, Kagaya H, Saito M, Inoue T, Habuchi T, Suzuki T. (2008). Influence of CYP3A5, ABCB1 and NR1I2 polymorphisms on prednisolone pharmacokinetics in renal transplant recipients. Steroids 73:1052–9.
  • Ogg MS, Williams JM, Tarbit M, Goldfarb PS, Gray TJ, Gibson GG. (1999). A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro. Xenobiotica 29:269–79.
  • Pascussi JM, Drocourt L, Fabre JM, Maurel P, Vilarem MJ. (2000a). Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators. Mol Pharmacol 58:361–72.
  • Pascussi JM, Drocourt L, Gerbal-Chaloin S, Fabre JM, Maurel P, Vilarem MJ. (2001). Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor. Eur J Biochem 268:6346–58.
  • Pascussi JM, Gerbal-Chaloin S, Drocourt L, Maurel P, Vilarem MJ. (2003). The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors. Biochim Biophys Acta 1619:243–53.
  • Pascussi JM, Gerbal-Chaloin S, Fabre JM, Maurel P, Vilarem MJ. (2000b). Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation. Mol Pharmacol 58:1441–50.
  • Pichard L, Fabre I, Daujat M, Domergue J, Joyeux H, Maurel P. (1992). Effect of corticosteroids on the expression of cytochromes P450 and on cyclosporin A oxidase activity in primary cultures of human hepatocytes. Mol Pharmacol 41:1047–55.
  • Quattrochi LC, Guzelian PS. (2001). CYP3A regulation: from pharmacology to nuclear receptors. Drug Metab Disposit 29:615–22.
  • Stevens A, Ray DW, Zeggini E, John S, Richards HL, Griffiths CE, Donn R. (2004). Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype. J Clin Endocrinol Metab 89:892–7.
  • Tanaka H, Imamura N, Oguma N, Shintani T, Tanaka K, Hyodo H, Oda K, Kimura A. (2001). Acute myelogenous leukemia with PIG-A gene mutation evolved from aplastic anemia-paroxysmal nocturnal hemoglobinuria syndrome. Int J Hematol 73:206–12.
  • Timsit YE, Negishi M. (2007). CAR and PXR: the xenobiotic-sensing receptors. Steroids 72:231–46.
  • Tirona RG, Lee W, Leake BF, Lan LB, Cline CB, Lamba V, Parviz F, Duncan SA, Inoue Y, Gonzalez FJ, Schuetz EG, Kim RB. (2003). The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4. Nat Med 9:220–4.
  • Van Rossum EF, Feelders RA, Van den Beld AW, Uitterlinden AG, Janssen JA, Ester W, Brinkmann AO, Grobbee DE, De Jong FH, Pols HA, Koper JW, Lamberts SW. (2004). Association of the ER22/23EK polymorphism in the glucocorticoid receptor gene with survival and C-reactive protein levels in elderly men. Am J Med 117:158–62.
  • Van Rossum EF, Koper JW, Huizenga NA, Uitterlinden AG, Janssen JA, Brinkmann AO, Grobbee DE, De Jong FH, Van Duyn CM, Pols HA, Lamberts SW. (2002). A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels. Diabetes 51:3128–34.
  • Weaver JU, Hitman GA, Kopelman PG. (1992). An association between a BclI restriction fragment length polymorphism of the glucocorticoid receptor locus and hyperinsulinaemia in obese women. J Mol Endocrinol 9:295–300.
  • Wu L, Xu X, Shen J, Xie H, Yu S, Liang T, Wang W, Shen Y, Zhang M, Zheng S. (2007). MDR1 gene polymorphisms and risk of recurrence in patients with hepatocellular carcinoma after liver transplantation. J Surg Oncol 96:62–8.
  • Wüst S, Van Rossum EF, Federenko IS, Koper JW, Kumsta R, Hellhammer DH. (2004). Common polymorphisms in the glucocorticoid receptor gene are associated with adrenocortical responses to psychosocial stress. J Clin Endocrinol Metab 89:565–73.
  • Yates CR, Chang C, Kearbey JD, Yasuda K, Schuetz EG, Miller DD, Dalton JT, Swaan PW. (2003). Structural determinants of P-glycoprotein-mediated transport of glucocorticoids. Pharmaceut Res 20:1794–803.
  • Zhang J, Kuehl P, Green ED, Touchman JW, Watkins PB, Daly A, Hall SD, Maurel P, Relling M, Brimer C, Yasuda K, Wrighton SA, Hancock M, Kim RB, Strom S, Thummel K, Russell CG, Hudson JR Jr, Schuetz EG, Boguski MS. (2001). The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants. Pharmacogenetics 11:555–72.

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