References
- Ashton JC. (2007). Cannabinoids for the treatment of inflammation. Curr Opin Investig Drugs 8:373–84
- Dalvie D, Chen W, Zhang C, et al. (2008). Pharmacokinetics, metabolism, and excretion of torcetrapib, a cholesteryl ester transfer protein inhibitor, in humans. Drug Metab Dispos 36:2185–98
- Herkenham M, Lynn AB, Little MD, et al. (1990). Cannabinoid receptor localization in brain. Proc Natl Acad Sci USA 87:1932–6
- International Conference on Harmonization. (2009) M3(R2): Guidance on Non-Clinical Safety Studies for the Conduct of Human Clinical Trials and Marketing Authorization for Pharmaceuticals. Available at: http://www.pharmafacts.com/images/stories/Resources/ICHM3R2.pdf [last accessed 22 July 2014]
- Leleu-Chavain N, Body-Malapel M, Spencer J, et al. (2012). Recent advances in the development of selective CB(2) agonists as promising anti-inflammatory agents. Curr Med Chem 19:3457–74
- Mailleux P, Vanderhaeghen JJ. (1992). Distribution of neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistry. Neuroscience 48:655–68
- Munro S, Thomas KL, Abu-Shaar M. (1993). Molecular characterization of a peripheral receptor for cannabinoids. Nature 365:61–5
- Odan M, Ishizuka N, Hiramatsu Y, et al. (2012). Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. Bioorg Med Chem Lett 22:2803–6
- Ong PY. (2009). Emerging drugs for atopic dermatitis. Expert Opin Emerg Drugs 14:165–79
- Riley P, Figary PC, Entwisle JR, et al. (2005). The metabolic profile of azimilide in man: in vivo and in vitro evaluations. J Pharm Sci 94:2084–95
- Sekiguchi K, Kanazu T, Takeuchi H, et al. (2013). Non-clinical evaluation of the metabolism, pharmacokinetics and excretion of S-777469, a new cannabinoid receptor 2 selective agonist. Xenobiotica 44:48–58
- US FDA. (2008). United States Food and Drug Administration Guidance for Industry, Safety testing of drug metabolites, February 2008. Available at: http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm065014.htm [last accessed 22 July 2014]
- Wang WW, Khetani SR, Krzyzewski S, et al. (2010). Assessment of a micropatterned hepatocyte coculture system to generate major human excretory and circulating drug metabolites. Drug Metab Dispos 38:1900–5