Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 45, 2015 - Issue 3
Submit an article Journal homepage
827
Views
19
CrossRef citations to date
0
Altmetric
Research Article

Protein binding of fentanyl and its metabolite nor-fentanyl in human plasma, albumin and α-1 acid glycoprotein

Sudeep Raj BistaSchool of Pharmacy, Griffith Health Institute, Griffith University, Gold Coast, QLD, Australia, ;Mater Medical Research Institute, Mater Pathology Services, South Brisbane, QLD, Australia, and Correspondence[email protected]
,
Alison HaywoodSchool of Pharmacy, Griffith Health Institute, Griffith University, Gold Coast, QLD, Australia, ;Mater Medical Research Institute, Mater Pathology Services, South Brisbane, QLD, Australia, and
,
Janet HardyMater Medical Research Institute, Mater Pathology Services, South Brisbane, QLD, Australia, and
,
Michael LobbMater Medical Research Institute, Mater Pathology Services, South Brisbane, QLD, Australia, and
,
Angela TapuniMater Medical Research Institute, Mater Pathology Services, South Brisbane, QLD, Australia, and
&
Ross NorrisSchool of Pharmacy, Griffith Health Institute, Griffith University, Gold Coast, QLD, Australia, ;Mater Medical Research Institute, Mater Pathology Services, South Brisbane, QLD, Australia, and ;SydPath, St Vincent’s Hospital, Sydney, NSW, Australia
Pages 207-212 | Received 13 Aug 2014, Accepted 26 Sep 2014, Published online: 14 Oct 2014

References

  • Bista SR, Lobb M, Haywood A, et al. (2014). Development, validation and application of an HPLC-MS/MS method for the determination of fentanyl and nor-fentanyl in human plasma and saliva. J Chromatogr B Analyt Technol Biomed Life Sci 960:27–33
  • Bower S. (1981). Plasma protein binding of fentanyl. J Pharm Pharmacol 33:507–14
  • Bowers WF, Fulton S, Thompson J. (1984). Ultrafiltration vs equilibrium dialysis for determination of free fraction. Clin Pharmacokinet 9:49–60
  • Brash JL, Lyman DJ. (1969). Adsorption of plasma proteins in solution to uncharged, hydrophobic polymer surfaces. J Biomed Mater Res 3:175–89
  • Goromaru T, Matsuura H, Yoshimura N, et al. (1984). Identification and quantitative determination of fentanyl metabolites in patients by gas chromatography – mass spectrometry. Anesthesiology 61:73–7
  • Guha Thakurta S, Subramanian A. (2011). Evaluation of in situ albumin binding surfaces: a study of protein adsorption and platelet adhesion. J Mater Sci Mater Med 22:137–49
  • Kremer JM, Wilting J, Janssen LH. (1988). Drug binding to human alpha-1-acid glycoprotein in health and disease. Pharmacol Rev 40:1–47
  • Kurz H, Trunk H, Weitz B. (1977). Evaluation of methods to determine protein-binding of drugs. Equilibrium dialysis, ultrafiltration, ultracentrifugation, gel filtration. Arzneimittelforschung 27:1373–80
  • Maguire P, Tsai N, Kamal J, et al. (1992). Pharmacological profiles of fentanyl analogs at mu, delta and kappa opiate receptors. Eur J Pharmacol 213:219–25
  • Mather LE. (1983). Clinical pharmacokinetics of fentanyl and its newer derivatives. Clin Pharmacokinet 8:422–46
  • Meuldermans WE, Hurkmans RM, Heykants JJ. (1982). Plasma protein binding and distribution of fentanyl, sufentanil, alfentanil and lofentanil in blood. Arch Int Pharmacodyn Ther 257:4–19
  • Miller RS, Peterson GM, Abbott F, et al. (1995). Plasma concentrations of fentanyl with subcutaneous infusion in palliative care patients. Br J Clin Pharmacol 40:553–6
  • Pacifici GM, Viani A. (1992). Methods of determining plasma and tissue binding of drugs. Pharmacokinetic consequences. Clin Pharmacokinet 23:449–68
  • Peters T. (1996). All about albumin: biochemistry, genetics, and medical applications. San Diego, CA: Academic Press
  • Rothschild MA, Oratz M, Schreiber SS. (1988). Serum albumin. Hepatology 8:385–401
  • Rowland M, Tozer TN. (2011). Clinical pharmacokinetics and pharmacodynamics: concepts and applications. Philadelphia, PA: Wolters Kluwer Health/Lippincott William & Wilkins
  • Shargel L, Wu-Pong S, Yu ABC, et al. (2005). Applied biopharmaceutics & pharmacokinetics. New York: Appleton & Lange Reviews/McGraw-Hill, Medical Pub. Division
  • Solassol I, Bressolle F, Caumette L, et al. (2005). Inter- and intraindividual variabilities in pharmacokinetics of fentanyl after repeated 72-hour transdermal applications in cancer pain patients. Ther Drug Monit 27:491–8
  • Streisand JB, Varvel JR, Stanski DR, et al. (1991). Absorption and bioavailability of oral transmucosal fentanyl citrate. Anesthesiology 75:223–9
  • Taylor S, Harker A. (2006). Modification of the ultrafiltration technique to overcome solubility and non-specific binding challenges associated with the measurement of plasma protein binding of corticosteroids. J Pharma Biomed Anal 41:299–303
  • Tesseromatis C, Alevizou A, Tigka E, et al. (2011). Acute-phase proteins: alpha-1-acid glycoprotein. In: Veas F, ed. Acute phase proteins – regulation and functions of acute phase proteins. Croatia, UK: In Tech. ISBN: 978-953-307-252-4
  • Wang C, Williams NS. (2013). A mass balance approach for calculation of recovery and binding enables the use of ultrafiltration as a rapid method for measurement of plasma protein binding for even highly lipophilic compounds. J Pharm Biomed Anal 75:112–17
  • Wiesner G, Taeger K, Peter K. (1996). Serum protein binding of fentanyl. The effect of postoperative acute phase reaction with elevated alpha 1-acid glycoprotein and methodologic problems in determination by equilibrium dialysis. Anaesthesist 45:323–9
  • Wilson AS, Stiller RL, Davis PJ, et al. (1997). Fentanyl and alfentanil plasma protein binding in preterm and term neonates. Anesth Analg 84:315–18
  • Wright JD, Boudinot FD, Ujhelyi MR. (1996). Measurement and analysis of unbound drug concentrations. Clin Pharmacokinet 30:445–62

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.