In vitro effects of standardized extract of Bacopa monniera and its five individual active constituents on human P-glycoprotein activity

References

• Appiah-Opong R, Commandeur JN, Van Vugt-Lussenburg B, Vermeulen NP. (2007). Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products. Toxicology 235:83–91
   PubMed Web of Science ®Google Scholar
• Bhattacharya SK, Bhattacharya A, Kumar A, Ghosal S. (2000). Antioxidant activity of Bacopa monniera in rat frontal cortex, striatum and hippocampus. Phytother Res 14:174–9
   PubMed Web of Science ®Google Scholar
• Colalto C. (2010). Herbal interactions on absorption of drugs: mechanisms of action and clinical risk assessment. Pharmacol Res 62:207–27
   PubMed Web of Science ®Google Scholar
• Dar A, Channa S. (1997). Bronchodilatory and cardiovascular effects of an ethanol extract of Bacopa monniera in anaesthetized rats. Phytomedicine 4:319–23
   PubMed Web of Science ®Google Scholar
• Dey S, Ramachandra M, Pastan I, et al. (1997). Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein. Proc Nat Acad Sci 94:10594–9
   PubMed Web of Science ®Google Scholar
• Egashira K, Ohtani H, Itoh S, et al. (2004). Inhibitory effects of pomelo on the metabolism of tacrolimus and the activities of CYP3A4 and P-glycoprotein. Drug Metab Dispos 32:828–33
   PubMed Web of Science ®Google Scholar
• Elangovan V, Govindasamy S, Ramamoorthy N, Balasu Bramanian K. (1995). In vitro studies on the anticancer activity of Bacopa monnieri. Fitoterapia 66:211–15
   Google Scholar
• Evans AM. (2000). Influence of dietary components on the gastrointestinal metabolism and transport of drugs. Ther Drug Monit 22:131–6
   PubMed Web of Science ®Google Scholar
• Funakoshi S, Murakami T, Yumoto R, et al. (2003). Role of P-glycoprotein in pharmacokinetics and drug interactions of digoxin and β-methyldigoxin in rats. J Pharm Sci 92:1455–63
   PubMed Web of Science ®Google Scholar
• Izzo AA, Ernst E. (2001). Interactions between herbal medicines and prescribed drugs: a systematic review. Drugs 61:2163–75
   PubMed Web of Science ®Google Scholar
• Ji B-S, He L, Liu G-Q. (2005). Modulation of P-glycoprotein function by amlodipine derivatives in brain microvessel endothelial cells of rats 1. Acta Pharmacol Sin 26:166–70
   PubMed Web of Science ®Google Scholar
• Kawai K-I, Shibata S. (1978). Pseudojujubogenin, a new sapogenin from Bacopa monniera. Phytochemistry 17:287–9
   Web of Science ®Google Scholar
• Kuppens IE, Breedveld P, Beijnen JH, Schellens JH. (2005). Modulation of oral drug bioavailability: from preclinical mechanism to therapeutic application. Cancer Invest 23:443–64
   PubMed Web of Science ®Google Scholar
• Lee J-S, Paull K, Alvarez M, et al. (1994). Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen. Mol Pharmacol 46:627–38
   PubMed Web of Science ®Google Scholar
• Moriguchi J, Kato R, Nakagawa M, et al. (2007). Effects of lipopolysaccharide on intestinal P-glycoprotein expression and activity. Eur J Pharmacol 565:220–4
   PubMed Web of Science ®Google Scholar
• Mosmann T. (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55–63
   PubMed Web of Science ®Google Scholar
• Oda K, Nemoto H, Nagasaka Y, et al. (2014). In vitro experimental system for evaluating inhibitory effect of investigational drugs on P-glycoprotein-mediated transcellular transport of tacrolimus (FK506). Biopharm Drug Dispos 35:135–44
   PubMed Web of Science ®Google Scholar
• Pal R, Sarin J. (1992). Quantitative determination of bacosides by UV-spectrophotometry. Indian J Pharm Sci 54:17–18
   Google Scholar
• Parasrampuria R, Mehvar R. (2008). Hepatobiliary disposition of rhodamine 123 in isolated perfused rat livers. Xenobiotica 38:1263–73
   Web of Science ®Google Scholar
• Perloff MD, Von Moltke LL, Störmer E, et al. (2001). Saint John's wort: an in vitro analysis of P-glycoprotein induction due to extended exposure. Br J Pharmacol 134:1601–8
   PubMed Web of Science ®Google Scholar
• Rao CV, Sairam K, Goel RK. (2000). Experimental evaluation of Bocopa monniera on rat gastric ulceration and secretion. Indian J Physiol Pharmacol 44:435–41
   PubMedGoogle Scholar
• Russo A, Borrelli F. (2005). Bacopa monniera, a reputed nootropic plant: an overview. Phytomedicine 12:305–17
   PubMed Web of Science ®Google Scholar
• Saini N, Mathur R, Agrawal S. (2012). Qualitative and quantitative assessment of four marketed formulations of Brahmi. Indian J Pharm Sci 74:24–8
   PubMed Web of Science ®Google Scholar
• Sairam K, Dorababu M, Goel RK, Bhattacharya SK. (2002). Antidepressant activity of standardized extract of Bacopa monniera in experimental models of depression in rats. Phytomedicine 9:207–11
   PubMed Web of Science ®Google Scholar
• Scala S, Akhmed N, Rao U, et al. (1997). P-glycoprotein substrates and antagonists cluster into two distinct groups. Mol Pharmacol 51:1024–33
   PubMed Web of Science ®Google Scholar
• Schuetz EG, Beck WT, Schuetz JD. (1996). Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. Mol Pharmacol 49:311–18
   PubMed Web of Science ®Google Scholar
• Shanmugasundaram ER, Akbar GK, Shanmugasundaram KR. (1991). Brahmighritham, an Ayurvedic herbal formula for the control of epilepsy. J Ethnopharmacol 33:269–76
   PubMed Web of Science ®Google Scholar
• Shapiro AB, Ling V. (1997). Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities. Eur J Biochem 250:130–7
   PubMedGoogle Scholar
• Singh R, Panduri J, Kumar D, et al. 2013. Evaluation of memory enhancing clinically available standardized extract of Bacopa monniera on P-glycoprotein and cytochrome P450 3A in Sprague-Dawley rats. PLoS One 8:e72517
   Google Scholar
• Tanigawara Y, Okamura N, Hirai M, et al. (1992). Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1). J Pharmacol Exp Ther 263:840–5
   PubMed Web of Science ®Google Scholar
• Trauner M, Arrese M, Soroka C, et al. (1997). The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis. Gastroenterology 113:255–64
   PubMed Web of Science ®Google Scholar
• Tripathi YB, Chaurasia S, Tripathi E, et al. (1996). Bacopa monniera Linn. as an antioxidant: mechanism of action. Indian J Exp Biol 34:523–6
   PubMedGoogle Scholar
• Uabundit N, Wattanathorn J, Mucimapura S, Ingkaninan K. (2010). Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model. J Ethnopharmacol 127:26–31
   PubMed Web of Science ®Google Scholar
• Ueda K, Okamura N, Hirai M, et al. (1992). Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone. J Biol Chem 267:24248–52
   PubMed Web of Science ®Google Scholar
• Wacher VJ, Wu CY, Benet LZ. (1995). Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy. Mol Carcinog 13:129–34
   PubMed Web of Science ®Google Scholar
• Walter-Sack I, Klotz U. (1996). Influence of diet and nutritional status on drug metabolism. Clin Pharmacokinet 31:47–64
   PubMed Web of Science ®Google Scholar
• Watkins PB. (1997). The barrier function of CYP3A4 and P-glycoprotein in the small bowel. Adv Drug Deliv Rev 27:161–70
   PubMed Web of Science ®Google Scholar
• Yumoto R, Murakami T, Sanemasa M, et al. (2001a). Pharmacokinetic interaction of cytochrome P450 3A-related compounds with rhodamine 123, a P-glycoprotein substrate, in rats pretreated with dexamethasone. Drug Metab Dispos 29:145–51
   PubMed Web of Science ®Google Scholar
• Yumoto R, Murakami T, Sanemasa M, et al. (2001b). Pharmacokinetic interaction of cytochrome P450 3A-related compounds with rhodamine 123, a P-glycoprotein substrate, in rats pretreated with dexamethasone. Drug metab Dispos 29:145–51
   PubMed Web of Science ®Google Scholar
• Zhang W, Lim L-Y. (2008). Effects of spice constituents on P-glycoprotein-mediated transport and CYP3A4-mediated metabolism in vitro. Drug Metab Dispos 36:1283–90
   PubMed Web of Science ®Google Scholar
• Zhang W, Tan TMC, Lim L-Y. (2007). Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats. Drug Metab Dispos 35:110–15
   PubMed Web of Science ®Google Scholar
• Zhu H-J, Wang J-S, Markowitz JS, et al. (2006). Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana. J Pharmacol Exp Ther 317:850–7
   PubMed Web of Science ®Google Scholar