Tissue-specific regulation of CYP3A by hydrolysable tannins in male pigs

References

• Achour B, Barber J, Rostami-Hodjegan A. (2011). Cytochrome P450 pig liver pie: determination of individual cytochrome P450 isoform contents in microsomes from two pig livers using liquid chromatography in conjunction with mass spectrometry. Drug Metab Dispos 39:2130–4
   PubMed Web of Science ®Google Scholar
• Anzenbacher P, Soucek P, Anzenbacherova E, et al. (1998). Presence and activity of cytochrome P450 isoforms in minipig liver microsomes. Comparison with human liver samples. Drug Metab Dispos 26:56–9
   PubMed Web of Science ®Google Scholar
• Bártíková H, Boušová I, Jedličková P, et al. (2014). Effect of standardized cranberry extract on the activity and expression of selected biotransformation enzymes in rat liver and intestine. Molecules 19:14948–60
   PubMed Web of Science ®Google Scholar
• Bergheim I, Bode C, Parlesak A. (2005). Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa. BMC Clin Pharmacol 5:4
   PubMedGoogle Scholar
• Biagi G, Cipollini I, Paulicks BR, Roth FX. (2010). Effect of tannins on growth performance and intestinal ecosystem in weaned piglets. Arch Anim Nutr 64:121–35
   PubMed Web of Science ®Google Scholar
• Candek-Potokar M, Skrlep M, Batorek Lukac N, et al. (2015). Hydrolysable tannin fed to entire male pigs affects intestinal production, tissue deposition and hepatic clearance of skatole. Vet J 204:162–7
   Google Scholar
• Danielson PB. (2002). The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans. Curr Drug Metab 3:561–97
   PubMed Web of Science ®Google Scholar
• Ekstrand B, Rasmussen MK, Woll F, et al. (2015). In vitro gender-dependent inhibition of porcine cytochrome p450 activity by selected flavonoids and phenolic acids. Biomed Res Int 2015:387918
   Google Scholar
• Espín JC, González-Barrio R, Cerdá B, et al. (2007). Iberian pig as a model to clarify obscure points in the bioavailability and metabolism of ellagitannins in humans. J Agric Food Chem 55:10476–85
   PubMed Web of Science ®Google Scholar
• Hidaka M, Okumura M, Fujita K, et al. (2005). Effects of pomegranate juice on human cytochrome p450 3A (CYP3A) and carbamazepine pharmacokinetics in rats. Drug Metab Dispos 33:644–8
   PubMed Web of Science ®Google Scholar
• Gao X, Bhattacharya S, Chan WK, et al. (2014). Expression of P-glycoprotein and CYP3A4 along the porcine oral-gastrointestinal tract: implications on oral mucosal drug delivery. Drug Dev Ind Pharm 40:599–603
   PubMed Web of Science ®Google Scholar
• Gonzalez-Sarrias A, Azorin-Ortuno M, Yanez-Gascon MJ, et al. (2009). Dissimilar.in vitro and in vivo effects of ellagic acid and its microbiota-derived metabolites, urolithins, on the cytochrome P450 1A1. J Agric Food Chem 57:5623–32
   PubMed Web of Science ®Google Scholar
• Johnson TN. (2003). The development of drug metabolising enzymes and their influence on the susceptibility to adverse drug reactions in children. Toxicology 192:37–48
   PubMed Web of Science ®Google Scholar
• Khanbabaee K, Van Tee T. (2001). Tannins: classification and definition. Nat Prod Rep 18:641–9
   PubMed Web of Science ®Google Scholar
• Kumarakulasingham M, Rooney PH, Dundas SR, et al. (2005). Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis. Clin Cancer Res 11:3758–65
   PubMed Web of Science ®Google Scholar
• Lampen A, Christians U, Gonschior AK, et al. (1996). Metabolism of the macrolide immunosuppressant, tacrolimus, by the pig gut mucosa in the Ussing chamber. Br J Pharmacol 117:1730–4
   PubMed Web of Science ®Google Scholar
• Landete JM. (2011). Ellagitannins, ellagic acid and their derived metabolites: a review about source, metabolism, functions and health. Food Res Int 44:1150–60
   Web of Science ®Google Scholar
• Li HC, Dehal SS, Kupfer D. (1995). Induction of the hepatic CYP2B and CYP3A enzymes by the proestrogenic pesticide methoxychlor and by DDT in the rat. Effects on methoxychlor metabolism. J Biochem Toxicol 10:51–61
   PubMedGoogle Scholar
• Lown KS, Bailey DG, Fontana RJ, et al. (1997). Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression. J Clin Invest 99:2545–53
   PubMed Web of Science ®Google Scholar
• Markowitz JS, Donovan JL, DeVane CL, et al. (2003). Effect of St John's wort on drug metabolism by induction of cytochrome P450 3A4 enzyme. JAMA 290:1500–4
   PubMed Web of Science ®Google Scholar
• McKinnon RA, Burgess WM, Hall PM, et al. (1995). Characterisation of CYP3A gene subfamily expression in human gastrointestinal tissues. Gut 36:259–67
   PubMed Web of Science ®Google Scholar
• Moon YJ, Wang X, Morris ME. (2006). Dietary flavonoids: effects on xenobiotic and carcinogen metabolism. Toxicol in Vitro 20:187–210
   PubMed Web of Science ®Google Scholar
• Nannelli A, Chirulli V, Longo V, Gervasi PG. (2008). Expression and induction by rifampicin of CAR- and PXR-regulated CYP2B and CYP3A in liver, kidney and airways of pig. Toxicology 252:105–12
   PubMed Web of Science ®Google Scholar
• Okuda T, Ito H. (2011). Tannins of constant structure in medicinal and food plants-hydrolyzable tannins and polyphenols related to tannins. Molecules 16:2191–217
   Web of Science ®Google Scholar
• Paine MF, Hart HL, Ludington SS, et al. (2006). The human intestinal cytochrome P450 “PIE”. Drug Metab Dispos 34:880–6
   PubMed Web of Science ®Google Scholar
• Pollock CB, Rogatcheva MB, Schook LB. (2007). Comparative genomics of xenobiotic metabolism: a porcine-human PXR gene comparison. Mamm Genome 18:210–19
   PubMed Web of Science ®Google Scholar
• Pu QH, Shi L, Yu C. (2015). Time-dependent inhibition of CYP3A4 by gallic acid in human liver microsomes and recombinant systems. Xenobiotica 45:213–17
   PubMed Web of Science ®Google Scholar
• Puccinelli E, Gervasi PG, La Marca M, et al. (2010). Expression and inducibility by phenobarbital of CYP2C33, CYP2C42, CYP2C49, CYP2B22, and CYP3As in porcine liver, kidney, small intestine, and nasal tissues. Xenobiotica 40:525–35
   PubMed Web of Science ®Google Scholar
• Puccinelli E, Gervasi PG, Longo V. (2011). Xenobiotic metabolizing cytochrome P450 in pig, a promising animal model. Curr Drug Metab 12:507–25
   PubMed Web of Science ®Google Scholar
• Rasmussen MK, Zamaratskaia G, Ekstrand B. (2011a). Gender-related differences in cytochrome P450 in porcine liver – implication for activity, expression and inhibition by testicular steroids. Reprod Domest Anim 46:616–23
   PubMed Web of Science ®Google Scholar
• Rasmussen M, Ekstrand B, Zamaratskaia G. (2011b). Comparison of cytochrome P450 concentrations and metabolic activities in porcine hepatic microsomes prepared with two different methods. Toxicol In Vitro 25:343–6
   PubMed Web of Science ®Google Scholar
• Rasmussen M, Zamaratskaia G. (2014). Regulation of porcine hepatic cytochrome P450 – implication for boar taint. Comput Struct Biotechnol J 11:106–12
   PubMedGoogle Scholar
• Rodeiro I, Donato MT, Lahoz A, et al. (2008). Interactions of polyphenols with the P450 system: possible implications on human therapeutics. Mini Rev Med Chem 8:97–106
   PubMed Web of Science ®Google Scholar
• Rosenberg DW. (1991). Dietary modulation of cytochrome P450 in the small intestinal epithelium. Pharmacology 43:36–46
   PubMed Web of Science ®Google Scholar
• Skaanild MT, Friis C. (1999). Cytochrome P450 sex differences in minipigs and conventional pigs. Pharmacol Toxicol 85:174–80
   PubMedGoogle Scholar
• Sohi G, Barry EJ, Velenosi TJ, et al. (2014). Protein restoration in low-birth-weight rat offspring derived from maternal low-protein diet leads to elevated hepatic CYP3A and CYP2C11 activity in adulthood. Drug Metab Dispos 42:221–8
   PubMed Web of Science ®Google Scholar
• Stupans I, Stretch G, Hayball P. (2000). Olive oil phenols inhibit human hepatic microsomal activity. J Nutr 130:2367–70
   PubMed Web of Science ®Google Scholar
• Van Peer E, Verbueken E, Saad M, et al. (2014). Ontogeny of CYP3A and P-glycoprotein in the liver and the small intestine of the Göttingen minipig: an immunohistochemical evaluation. Basic Clin Pharmacol Toxicol 114:387–94
   PubMed Web of Science ®Google Scholar
• Vang O, Frandsen H, Hansen KT, et al. (2001). Biochemical effects of dietary intakes of different broccoli samples. I. Differential modulation of cytochrome P-450 activities in rat liver, kidney, and colon. Metab Clin Exp 50:1123–9
   PubMed Web of Science ®Google Scholar
• Werk AN, Cascorbi I. (2014). Functional gene variants of CYP3A4. Clin Pharmacol Ther 96:340–8
   PubMed Web of Science ®Google Scholar
• Yao HT, Chang YW, Lan SJ, Yeh TK. (2008). The inhibitory effect of tannic acid on cytochrome P450 enzymes and NADPH-CYP reductase in rat and human liver microsomes. Food Chem Toxicol 46:645–53
   PubMed Web of Science ®Google Scholar
• Zlabek V, Zamaratskaia G. (2012). Comparison of three fluorescent CYP3A substrates in two vertebrate models: pig and Atlantic salmon. Animal 6:633–40
   Google Scholar