The hepatic metabolism and biliary excretion of benzo[a]pyrene in guinea-pigs fed normal, high-fat or high-cholesterol diets

References

• Abou-El-Makarem M.M., Millburn P., Smith R.L., Williams R.T. Biliary excretion of foreign compounds. Species differences in biliary excretion. Biochemical Journal 1967; 105: 1289–1293
   PubMed Web of Science ®Google Scholar
• Akerboom T.P.M., Sies H. Assay of glutathione, glutathione disulphide and glutathione mixed disulphides in biological samples. Methods in Enzymology 1981; 77: 373–382
   PubMedGoogle Scholar
• Armstrong B., Doll R. Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices. International Journal of Cancer 1975; 15: 617–631
   PubMed Web of Science ®Google Scholar
• Autrup H., Grafstrom R.C., Brugh M., Lechner J.F., Haugen A., Trump B.F., Harris C.C. Comparison of benzo[a]pyrene metabolism in bronchus, oesophagus, colon, and duodenum from the same individual. Cancer Research 1982; 42: 934–938
   PubMed Web of Science ®Google Scholar
• Booth J., Boyland E., Sato T., Sims P. Metabolism of polycyclic compounds. The reaction of 1,2-dihydronaphthalene 1,2-epoxy-1,2,3,4-tetrahydronaphthalene with glutathione catalysed by tissue preparations. Biochemical Journal 1960a; 77: 182–186
   PubMed Web of Science ®Google Scholar
• Booth J., Boyland E., Sims P. Metabolism of polycyclic compounds. The conversion of naphthalene into a derivative of glutathione by rat liver slices. Biochemical Journal 1960b; 74: 117–122
   PubMed Web of Science ®Google Scholar
• Bowes S.G., Renwick A.G. The intestinal metabolism and DNA binding of benzo[a]pyrene in guinea-pigs fed normal, high-fat and high-cholesterol diets. Xenoinotica 1986; 16: 543–553
   PubMed Web of Science ®Google Scholar
• Chipman J.K., Hirom P.C., Frost G.S., Millburn P. The biliary excretion and enterohepatic circulation of bcnzo[a]pyrene and its metabolites in the rat. Biochemical Pharmacology 1981; 30: 937–944
   PubMed Web of Science ®Google Scholar
• Chipman J.K., Bhave N.A., Hirom P.C., Millburn P. Metabolism and excretion of benzo[a]pyrene in the rabbit. Xenobiotica 1982; 12: 397–404
   PubMed Web of Science ®Google Scholar
• Cohen G.M., Moore B.P. Metabolism of [3H]benzo[a]pyrene by different portions of the respiratory track. Biochemical Pharmacology 1976; 25: 1623–1629
   PubMed Web of Science ®Google Scholar
• Cruse J.P., Lewin M.R., Ferulano G.P., Clark C.G. Co-carcinogenic effects of dietary cholesterol in experimental colon cancer. Nature 1978; 276: 822–825
   PubMed Web of Science ®Google Scholar
• Drasar B.S., Irving D. Environmental factors and cancer of the colon and breast. British Journal of Cancer 1973; 27: 167–172
   PubMed Web of Science ®Google Scholar
• Haenszel W., Dawson E.A. A note on mortality from cancer of the colon and rectum in the United States. Cancer 1965; 18: 265–272
   PubMedGoogle Scholar
• Haslewood G. Appendix: Bile salts in different animal forms. Bile Salts. Methuen, London 1967; 82–107
   Google Scholar
• Hirom P.C., Millburn P., Smith R.L., Williams R.T. Species variations in the threshold molecular weight factor for the biliary excretion of organic anions. Biochemical Journal 1972; 129: 1071–1077
   PubMed Web of Science ®Google Scholar
• Hundley S.G., Freudenthal R.I. A comparison of benzo[a]pyrene metabolism by liver and lung microsomal enzymes from 3-methylcholanthrene-treated rhesus monkeys and rats. Cancer Research 1977; 37: 3120–3125
   PubMed Web of Science ®Google Scholar
• Jain M., Cook G.M., Davis F.G., Grace M.G., Howe G.R., Miller A.B. A case-control study of diet and colo-rectal cancer. International Journal of Cancer 1980; 26: 757–768
   PubMed Web of Science ®Google Scholar
• Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 1951; 193: 265–275
   PubMed Web of Science ®Google Scholar
• Mass M., Modan B. Epidemiological aspects of neoplastic disorders in Israeli migrant population. IV. Cancer of the colon and rectum. Journal of the National Cancer Institute 1969; 42: 529–536
   PubMedGoogle Scholar
• Mazel P. Experiments illustrating drug metabolism in vitro. Fundamentals of Drug Metabolism and Drug Disposition, B.N. La Du, H.G. Mandel, E.L. Way. Williams and Wilkens, Baltimore 1971; 546–582
   Google Scholar
• Miller G.L. Protein determination for large numbers of samples. Analytical Chemistry 1959; 31: 964
   Web of Science ®Google Scholar
• Narisawa T., Magadia N.E., Weisburger J.H., Wynder E.L. Promoting effect of bile acids on colon carcinogenesis after intra-rectal instillation of N-methyl-N'-nitro-N-nitrosoguanidine in rats. Journal of the National Cancer Institute 1974; 53: 1093–1097
   PubMedGoogle Scholar
• Nebert D.W., Gelboin H.V. Substrate inducible microsomal aryl hydroxylase in mammalian cell culture. Journal of Biological Chemistry 1968; 243: 6242–6249
   PubMed Web of Science ®Google Scholar
• Oesch F., Jerina D.M., Daly J. A radiometric assay for hepatic epoxide hydrase activity with [7-3H]styrene oxide. Biochimica et Biophysica Acta 1971; 227: 685–691
   PubMed Web of Science ®Google Scholar
• Owens C.W.I., Belcher R.V. A colorimetric micro-method for the determination of glutathione. Biochemical Journal 1965; 94: 705–711
   PubMed Web of Science ®Google Scholar
• Plummer J.L., Smith B.R., Ball L.M., Bend J.R. Metabolism and biliary excretion of benzo[a]pyrene, 4,5-oxide in the rat. Drug Metabolism and Disposition 1980; 8: 68–72
   PubMed Web of Science ®Google Scholar
• Pue M.A., Frost G.S., Hirom P.C. The enterohepatic circulation of a glutathione conjugate of naphthalene in the rat. Biochemical Society Transactions 1982; 10: 112
   Google Scholar
• Racker E. The mechanism of action of glyoxalase. Journal of Biological Chemistry 1951; 190: 685–696
   PubMed Web of Science ®Google Scholar
• Reddy B.S., Narisawa T., Weisburger J.H., Wynder E.L. Promoting effect of sodium deoxycholate on colon adenocarcinomas in germ-free rats. Journal of the National Cancer Institute 1976; 56: 441–442
   PubMed Web of Science ®Google Scholar
• Reddy B.S., Mangat S., Weisburger J.H., Wynder E.L. Effect of high-risk diets for colon carcinogenesis on intestinal mucosal and bacterial β-glucuronidase activity in F344 rats. Cancer Research 1977a; 37: 3533–3536
   PubMed Web of Science ®Google Scholar
• Reddy B.S., Watanabe K., Weisburger J.H., Wynder E.L. Promoting effect of bile acids in colon carcinogenesis in germ-free and conventional F344 rats. Cancer Research 1977b; 37: 3238–3242
   PubMed Web of Science ®Google Scholar
• Renwick A.G., Drasar B.S. Environmental carcinogens and large bowel cancer. Nature 1976; 263: 234–235
   PubMed Web of Science ®Google Scholar
• Skidegård J., Dk Pierre J.W., Moron M.S., Johannesen K.A.M., Ernster L. Characterization of rat lung epoxide (styrene oxide) hydrase with a modified radioactive assay of improved sensitivity. Cancer Research 1977; 37: 1075–1082
   PubMedGoogle Scholar
• Selkirk J.K., Croy R.G., Whitlock J.P., Jr, Gelboin H.V. In vitro metabolism of benzo[a]pyrene by human liver microsomes and lymphocytes. Cancer Research 1975; 35: 3651–3655
   PubMed Web of Science ®Google Scholar
• Sies H., Wahllander A., Waydhas C., Soboll S., Haberle D. Functions of intracellular glutathione in hepatic hydroreroxide and drug metabolism and the role of extracellular glutathione. Advances in Enzyme Regulation 1980; 18: 303–320
   PubMedGoogle Scholar
• Smith R.L., Millburn P. Enterohepatic circulation and drug bioavaiiability. Proceedings of the 6th International Congress of Pharmacology 1977; 6: 77–88
   Google Scholar
• Stohs S.G., Grafstrom R.C., Burke M.D., Orrenius S. Benzo[a]pyrene metabolism by isolated rat intestinal epithelial cells. Archives of Biochemistry and Biophysics 1977; 179: 71–80
   PubMed Web of Science ®Google Scholar
• Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidised glutathione: applications to mammalian blood and other tissues. Analytical Biochemistry 1969; 27: 502–522
   PubMed Web of Science ®Google Scholar
• Vessey D.A., Zakim D. Inhibition of glutathione-S-transferase by bile acids. Biochemical Journal 1981; 197: 321–325
   PubMed Web of Science ®Google Scholar
• Wills E.D. Effects of dietary lipids on the metabolism of polycyclic hydrocarbons and the binding of their metabolites to DNA. Biochemical Society Transactions 1983; 11: 258–261
   PubMedGoogle Scholar
• Wynder E.L., Shigematsu T. Environmental factors and cancer of the colon and rectum. Cancer 1967; 20: 1520–1561
   PubMed Web of Science ®Google Scholar
• Yang S.K., Gelboin H.V. Microsomal mixed function oxidases and epoxide hydratase convert benzo[a]pyrene stereospecifically to optically active dihydroxydihydrobenzo[a]pyrenes. Biochemical Pharmacology 1976; 25: 2221–2225
   PubMed Web of Science ®Google Scholar