Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 9
11
Views
7
CrossRef citations to date
0
Altmetric
Research Article

Effects of picloram on xenobiotic biotransformation in rat liver

, &
Pages 1057-1066 | Received 15 Jul 1986, Published online: 22 Sep 2008

References

  • Spray Data Sheet. Farm. The Business Magazine of Australian Agriculture 1984, Suppl. 5, Anonymous
  • Boobis A. R., Nebert D. W., Felton J. S. Comparison of β-naphthoflavone and 3-methylcholanthrene as inducers of hepatic cytochrome(s) P-448 and aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity. Molecular Pharmacology 1977; 13: 259–268
  • Boobis A. R., McQuade J., Sesardic D., Robson R. T., Hayward C., Lock E. A., Elcombe C. R., Rose M. S., Davies D. S. A monoclonal antibody raised to rat liver cytochrome P-448 (form c) which recognises an epitope common to many other forms of cytochrome P-450. Biochemical Pharmacology 1985; 34: 1671–1681
  • Burke M. D., Prough R. A., Mayer R. T. Characteristics of a microsomal cytochrome P-448 mediated reaction. Drug Metabolism and Disposition 1977; 5: 1–8
  • Carere A., Ortali V. A., Cardamone G., Torracca A. M., Raschetti R. Microbiological mutagenicity studies of pesticides, in vitro. Mutation Research 1978; 57: 277–286
  • Chaykin S. Biochemistry Laboratory Techniques. John Wiley and Sons, New York 1966
  • Creaven P. J., Parke D. V. The stimulation of hydroxylation by carcinogenic and non-carcinogenic compounds. Biochemical Pharmacology 1966; 15: 7–16
  • Fox T. R., Reitz R. H., Watanabe P. G. Evaluation of the genotoxic potential of picloram herbicide in F344 rats. Toxicologist 1984; 4: 40
  • Guengerich F. P. Microsomal enzymes involved in toxicology—analysis and separation. Principles and Methods of Toxicology, A. Wallace Hayes. Raven Press, New York 1982; 609–634
  • Guengerich F. P., Dannan S. T., Wright S. T., Martin M. V., Kaminsky L. S. Purification and characterization of microsomal cytochrome P-450s. Xenobiotica 1982; 12: 701–716
  • Ioannides C., Lum P. Y., Parke D. V. Cytochrome P-448 and the activation of toxic chemicals and carcinogens. Xenobiotica 1984; 14: 119–137
  • Jefcoate C. R. Measurement of substrate and inhibitor binding to microsomal cytochrome P-450 by optical-difference spectroscopy. Methods in Enzymology, S. Fleischer, L. Parker. Academic Press, New York 1978; Vol. 52C: 258–279
  • Johnson K. A., Landry T. D., Gorzinoki S. J., Cieszlak F. S., Kropscott B. E., Wolfe E. L. Picloram: a two-year chronic toxicity and oncogenicity study in Fischer 344 rats. Toxicologist 1986; 6: 83
  • Kearney P. C., Kaufman D. D. Herbicides: Chemistry, Degradation, Mode of Action, 2nd edition. Bekker, New York 1976
  • Kulkarni A. P., Fabacher D. L., Hodgson E. Pesticides as inducers of hepatic drug metabolizing enzymes—II. Glutathione S-transferases. General Pharmacology 1980; 11: 437–441
  • Mazel P. Experiments illustrating drug metabolism in vitro. Fundamentals of Drug Metabolism and Drug Disposition, B. N. La Du, H. G. Mandel, E. L. Way. Williams and Wilkins, Baltimore 1972; 546–582
  • National Cancer Institute. Bioassay of Picloram for Possible Carcinogenicity. 1978, Carcinogenesis Technical Reports Series, No. 23 NCI-CG-TR-23.
  • National Toxicology Program. Fiscal Year 1985 Annual Plan. Public Health Service US Department of Health and Human Services. 1985, NTP-85–055
  • Newman S. L., Guzelian P. S. Identification of the cyanopregnenolone-inducible form of hepatic cytochrome P-450 as a catalyst of aldrin epoxidation. Biochemical Pharmacology 1983; 32: 1529–1531
  • Nolan R. J., Freshour P. E., Kastil P. E., Saunders J. H. Pharmacokinetics of picloram in male volunteers. Toxicology and Applied Pharmacology 1984; 76: 264–269
  • Omura T., Sato R. The CO binding pigment of liver microsomes. Evidence for its hemoprotein nature. Journal of Biological Chemistry 1964; 239: 2370–2378
  • Parke D. V. Control of the expression of genes coding for drug-induced proteins. Survey of drug metabolising enzymes. Biochemical Society Transactions 1983; 11: 457–458
  • Parke D. V., Gray T. J. E. A comparative study of the enzymic and morphological changes of livers of rats fed butylated hydroxytoluene, Safrole, Ponceau Mx, or 2-acetamidofluorene. Primary Liver Tumours, H. Remmer, H. M. Bolt, P. Bannasch, H. Popper. MTP Press, Lancaster 1978; 335–346
  • Parke D. V., Ioannides C. Role of mixed-function oxidases in the formation of biological reactive intermediates. Advances in Experimental Medicine and Biology 1982; 135A: 23–38
  • Prough R. A., Burke M. D., Mayer R. T. Direct fluorometric methods for measuring mixed function oxidase activity. Methods in Enzymology, S. Fleischer, L. Packer. Academic Press, New York 1978; Vol. 52C: 258–279
  • Reuber M. D. Carcinogenicity of picloram. Journal of Toxicology and Environmental Health 1981; 7: 207–222
  • Robens J. F. Carcinogenicity studies of selected herbicides. Veterinary and Human Toxicology 1980; 22: 328–334
  • Ryan D. E., Thomas P. E., Reik L. M., Levin W. Purification, characterization and regulation of five hepatic microsomal cytochrome P-450 isozymes. Xenobiotica 1982; 12: 727–744
  • Snedecor G. W., Cochran W. G. Statistical Methods, 7th edition. Iowa State University Press, Iowa 1980
  • Suschetet M., Le Clerc J., Lhuissier M., Loisei W. Toxicity and nutritional effects in the rat of 2 herbicides: picloram and atrazine. Annales De La Nutrition Et De L'Alimentation 1974; 28: 29–47
  • Taylor G., Houston J. B., Elcombe C. R. Effect of Promethazine and Isosafrole on rat hepatic microsomal mono-oxygenase activity: comparison with classic inducers phenobarbitone and β-naphthoflavone. Xenobiotica 1985; 15: 243–249
  • Wilkinson C. F., Denison M. S. Pesticide interactions with biotransformation systems. Effects of Chronic Exposures to Pesticides on Animal Systems, J. E. Chambers, J. D. Yarbrough. Raven Press, New York 1982; 1–24
  • Wolff T., Deml E., Wanders H. Aldrin epoxidation a highly sensitive indicator specific for P-450 dependent monoxygenase activities. Drug Metabolism and Disposition 1979; 7: 301–305
  • Woodruff R. C., Phillips J. P., Irwan D. Pesticide-induced complete and partial chromosome loss in screens with repair-defective females of. Drosophila melanogaster. Environmental Mutagenesis 1983; 5: 835–846
  • Yeowell H. N., Linko P., Hodgson E., Goldstein J. A. Induction of specific cytochrome P-450 isozymes by methylenedioxyphenyl compounds and antagonism by 3-methylcholanthrene. Archives of Biochemistry and Biophysics 1985; 243: 408–419

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.